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Items: 20


Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells.

Keating R, Morris MY, Yue W, Reynolds CE, Harris TL, Brown SA, Doherty PC, Thomas PG, McGargill MA.

Immunol Cell Biol. 2018 Jul 4. doi: 10.1111/imcb.12189. [Epub ahead of print]


Extracellular Signal-Regulated Kinase Signaling in CD4-Expressing Cells Inhibits Osteochondromas.

Wehenkel M, Corr M, Guy CS, Edwards BA, Castellaw AH, Calabrese C, Pagès G, Pouysségur J, Vogel P, McGargill MA.

Front Immunol. 2017 May 1;8:482. doi: 10.3389/fimmu.2017.00482. eCollection 2017.


mTOR Regulation of Lymphoid Cells in Immunity to Pathogens.

Keating R, McGargill MA.

Front Immunol. 2016 May 11;7:180. doi: 10.3389/fimmu.2016.00180. eCollection 2016. Review.


Drak2 Does Not Regulate TGF-β Signaling in T Cells.

Harris TL, McGargill MA.

PLoS One. 2015 May 7;10(5):e0123650. doi: 10.1371/journal.pone.0123650. eCollection 2015.


Drak2 is not required for tumor surveillance and suppression.

Edwards BA, Harris TL, Floersh H, Lukens JR, Zaki MH, Vogel P, Kanneganti TD, Bui JD, McGargill MA.

Int Immunol. 2015 Mar;27(3):161-6. doi: 10.1093/intimm/dxu146. Epub 2015 Jan 7.


The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.

Keating R, Hertz T, Wehenkel M, Harris TL, Edwards BA, McClaren JL, Brown SA, Surman S, Wilson ZS, Bradley P, Hurwitz J, Chi H, Doherty PC, Thomas PG, McGargill MA.

Nat Immunol. 2013 Dec;14(12):1266-76. doi: 10.1038/ni.2741. Epub 2013 Oct 20.


TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation.

Anand PK, Tait SW, Lamkanfi M, Amer AO, Nunez G, Pagès G, Pouysségur J, McGargill MA, Green DR, Kanneganti TD.

J Biol Chem. 2011 Dec 16;286(50):42981-91. doi: 10.1074/jbc.M111.310599. Epub 2011 Oct 27.


Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity.

Shaw PJ, Barr MJ, Lukens JR, McGargill MA, Chi H, Mak TW, Kanneganti TD.

Immunity. 2011 Jan 28;34(1):75-84. doi: 10.1016/j.immuni.2010.12.015. Epub 2011 Jan 13.


Foxo transcription factors control regulatory T cell development and function.

Kerdiles YM, Stone EL, Beisner DR, McGargill MA, Ch'en IL, Stockmann C, Katayama CD, Hedrick SM.

Immunity. 2010 Dec 14;33(6):890-904. doi: 10.1016/j.immuni.2010.12.002. Erratum in: Immunity. 2011 Jan 28;34(1):135. Beisner, Daniel L [corrected to Beisner, Daniel R].


Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis.

Shaw PJ, Lukens JR, Burns S, Chi H, McGargill MA, Kanneganti TD.

J Immunol. 2010 May 1;184(9):4610-4. doi: 10.4049/jimmunol.1000217. Epub 2010 Apr 5.


Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells.

McGargill MA, Ch'en IL, Katayama CD, Pagès G, Pouysségur J, Hedrick SM.

J Immunol. 2009 Oct 15;183(8):4838-42. doi: 10.4049/jimmunol.0902208.


Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7.

Hayashi T, Gray CS, Chan M, Tawatao RI, Ronacher L, McGargill MA, Datta SK, Carson DA, Corr M.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2764-9. doi: 10.1073/pnas.0813037106. Epub 2009 Feb 2.


Drak2 regulates the survival of activated T cells and is required for organ-specific autoimmune disease.

McGargill MA, Choy C, Wen BG, Hedrick SM.

J Immunol. 2008 Dec 1;181(11):7593-605.


Active Ca2+/calmodulin-dependent protein kinase II gamma B impairs positive selection of T cells by modulating TCR signaling.

McGargill MA, Sharp LL, Bui JD, Hedrick SM, Calbo S.

J Immunol. 2005 Jul 15;175(2):656-64.


A deficiency in Drak2 results in a T cell hypersensitivity and an unexpected resistance to autoimmunity.

McGargill MA, Wen BG, Walsh CM, Hedrick SM.

Immunity. 2004 Dec;21(6):781-91.


A spontaneous CD8 T cell-dependent autoimmune disease to an antigen expressed under the human keratin 14 promoter.

McGargill MA, Mayerova D, Stefanski HE, Koehn B, Parke EA, Jameson SC, Panoskaltsis-Mortari A, Hogquist KA.

J Immunol. 2002 Aug 15;169(4):2141-7.


Receptor editing in developing T cells.

McGargill MA, Derbinski JM, Hogquist KA.

Nat Immunol. 2000 Oct;1(4):336-41.


T cell receptor editing.

McGargill MA, Hogquist KA.

Immunol Lett. 2000 Dec 1;75(1):27-31. Review. No abstract available.


Antigen-induced coreceptor down-regulation on thymocytes is not a result of apoptosis.

McGargill MA, Hogquist KA.

J Immunol. 1999 Feb 1;162(3):1237-45.


Identification of a naturally occurring ligand for thymic positive selection.

Hogquist KA, Tomlinson AJ, Kieper WC, McGargill MA, Hart MC, Naylor S, Jameson SC.

Immunity. 1997 Apr;6(4):389-99.

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