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A novel plasmid-encoded mcr-4.3 gene in a colistin-resistant Acinetobacter baumannii clinical strain.

Martins-Sorenson N, Snesrud E, Xavier DE, Cacci LC, Iavarone AT, McGann P, Riley LW, Moreira BM.

J Antimicrob Chemother. 2019 Oct 3. pii: dkz413. doi: 10.1093/jac/dkz413. [Epub ahead of print]


Contribution of the Transforming Clinical Practice Initiative in Advancing the Movement to Value-Based Care.

Abraham MR, McGann P.

Ann Fam Med. 2019 Aug 12;17(Suppl 1):S6-S8. doi: 10.1370/afm.2425. No abstract available.


Robust clinical and laboratory response to hydroxyurea using pharmacokinetically guided dosing for young children with sickle cell anemia.

McGann PT, Niss O, Dong M, Marahatta A, Howard TA, Mizuno T, Lane A, Kalfa TA, Malik P, Quinn CT, Ware RE, Vinks AA.

Am J Hematol. 2019 Aug;94(8):871-879. doi: 10.1002/ajh.25510. Epub 2019 Jun 12.


Use of whole-genome sequencing to guide a Clostridioides difficile diagnostic stewardship program.

Jakharia KK, Ilaiwy G, Moose SS, Waga M, Appalla L, McAlduff JD, Karanfil LV, McGann PT, Wortmann GW.

Infect Control Hosp Epidemiol. 2019 Jul;40(7):804-806. doi: 10.1017/ice.2019.124. Epub 2019 May 15.


Hydroxyurea for children with sickle cell anemia: Prescribe it early and often.

Ware RE, McGann PT, Quinn CT.

Pediatr Blood Cancer. 2019 Aug;66(8):e27778. doi: 10.1002/pbc.27778. Epub 2019 Apr 30. No abstract available.


Non-transfusion-dependent β-Thalassemia Because of a Single β-Thalassemia Mutation and Coinherited α-Globin Gene Triplication: Need for Increased Awareness to Prevent Incorrect and Delayed Diagnosis.

Gurunathan A, Tarango C, McGann PT, Niss O, Quinn CT.

J Pediatr Hematol Oncol. 2019 Apr 8. doi: 10.1097/MPH.0000000000001470. [Epub ahead of print]


Rapid detection of colistin resistance protein MCR-1 by LC-MS/MS.

Wang H, Chen Y, Strich JR, Drake SK, Youn JH, Rosenberg AZ, Gucek M, McGann PT, Suffredini AF, Dekker JP.

Clin Proteomics. 2019 Feb 26;16:8. doi: 10.1186/s12014-019-9228-2. eCollection 2019.


Identification of the OXA-48 Carbapenemase Family by Use of Tryptic Peptides and Liquid Chromatography-Tandem Mass Spectrometry.

Strich JR, Wang H, Cissé OH, Youn JH, Drake SK, Chen Y, Rosenberg AZ, Gucek M, McGann PT, Dekker JP, Suffredini AF.

J Clin Microbiol. 2019 Apr 26;57(5). pii: e01240-18. doi: 10.1128/JCM.01240-18. Print 2019 May.


Bacteraemia due to Microbacterium paraoxydans in a patient with chronic kidney disease, refractory hypertension and sarcoidosis.

Chorost MS, Smith NC, Hutter JN, Ong AC, Stam JA, McGann PT, Hinkle MK, Schaecher KE, Kamau E.

JMM Case Rep. 2018 Oct 31;5(11):e005169. doi: 10.1099/jmmcr.0.005169. eCollection 2018 Nov.


A Rapidly Fatal Infection With Haemophilus influenzae Serotype E Harboring bla ROB-1: The Dilemma of Safe De-escalation in the Setting of Potential Extended-Spectrum β-Lactamase Production.

Hanna J, Ogunsesan Y, Snesrud E, Maybank R, Ong A, Kwak Y, Jones A, McGann P, Lesho E.

Open Forum Infect Dis. 2018 Nov 12;5(12):ofy302. doi: 10.1093/ofid/ofy302. eCollection 2018 Dec. No abstract available.


Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa.

Tshilolo L, Tomlinson G, Williams TN, Santos B, Olupot-Olupot P, Lane A, Aygun B, Stuber SE, Latham TS, McGann PT, Ware RE; REACH Investigators.

N Engl J Med. 2019 Jan 10;380(2):121-131. doi: 10.1056/NEJMoa1813598. Epub 2018 Dec 1.


An intervention to control an ICU outbreak of carbapenem-resistant Acinetobacter baumannii: long-term impact for the ICU and hospital.

Ben-Chetrit E, Wiener-Well Y, Lesho E, Kopuit P, Broyer C, Bier L, Assous MV, Benenson S, Cohen MJ, McGann PT, Snesrud E, Levin PD.

Crit Care. 2018 Nov 21;22(1):319. doi: 10.1186/s13054-018-2247-y.


Prevalence of inherited blood disorders and associations with malaria and anemia in Malawian children.

McGann PT, Williams AM, Ellis G, McElhinney KE, Romano L, Woodall J, Howard TA, Tegha G, Krysiak R, Lark RM, Ander EL, Mapango C, Ataga KI, Gopal S, Key NS, Ware RE, Suchdev PS.

Blood Adv. 2018 Nov 13;2(21):3035-3044. doi: 10.1182/bloodadvances.2018023069.


Hereditary elliptocytosis-associated alpha-spectrin mutation p.L155dup as a modifier of sickle cell disease severity.

Risinger M, Christakopoulos GE, Schultz CL, McGann PT, Zhang W, Kalfa TA.

Pediatr Blood Cancer. 2019 Feb;66(2):e27531. doi: 10.1002/pbc.27531. Epub 2018 Nov 4.


Successful Use of Colistin Monotherapy as Outpatient Parenteral Antibiotic Therapy for XDR Acinetobacter Hepatic Abscesses.

Prestwood J, Chang D, McGann P, Barsoumian AE.

Mil Med. 2019 Mar 1;184(3-4):e311-e313. doi: 10.1093/milmed/usy241.


Clinical and Genomic Features of the First Cases of Elizabethkingia anophelis Infection in New York, Including the First Case in a Healthy Infant Without Previous Nosocomial Exposure.

Snesrud E, McGann P, Walsh E, Ong A, Maybank R, Kwak Y, Campbell J, Jones A, Vore K, Hinkle M, Lesho E.

J Pediatric Infect Dis Soc. 2019 Jul 1;8(3):269-271. doi: 10.1093/jpids/piy071.


The Collaborative Role of North American Departments of Pediatrics in Global Child Health.

Gladding SP, McGann PT, Summer A, Russ CM, Uwemedimo OT, Matamoros Aguilar M, Chakraborty R, Moore M, Lieh-Lai M, Opoka R, Howard C, John CC; Global Health Task Force of the American Board of Pediatrics.

Pediatrics. 2018 Jul;142(1). pii: e20172966. doi: 10.1542/peds.2017-2966. Epub 2018 Jun 12. Review.


Chromosomally Encoded mcr-5 in Colistin-Nonsusceptible Pseudomonas aeruginosa.

Snesrud E, Maybank R, Kwak YI, Jones AR, Hinkle MK, McGann P.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00679-18. doi: 10.1128/AAC.00679-18. Print 2018 Aug.


Genomic Characterization of Nonclonal mcr-1-Positive Multidrug-Resistant Klebsiella pneumoniae from Clinical Samples in Thailand.

Srijan A, Margulieux KR, Ruekit S, Snesrud E, Maybank R, Serichantalergs O, Kormanee R, Sukhchat P, Sriyabhaya J, Hinkle M, Crawford JM, McGann P, Swierczewski BE.

Microb Drug Resist. 2018 May;24(4):403-410. doi: 10.1089/mdr.2017.0400. Epub 2018 Apr 24.


Model-based dosing with concentration feedback as an integral part of personalized hydroxycarbamide management.

Dong M, McGann PT, Mizuno T, Ware RE, Vinks AA.

Br J Clin Pharmacol. 2018 Jul;84(7):1410-1412. doi: 10.1111/bcp.13585. Epub 2018 Apr 17. No abstract available.


Got GAS? Ease the Bloat with Real-Time Whole-Genome Sequencing.

Lesho EP, Snesrud E, Bronstein M, Pettis M, Ong A, Maybank R, Kwak Y, Jones A, Vore K, McGann P, Hinkle M.

Infect Control Hosp Epidemiol. 2018 Jun;39(6):760-762. doi: 10.1017/ice.2018.73. Epub 2018 Apr 2. No abstract available.


The Birth and Demise of the ISApl1-mcr-1-ISApl1 Composite Transposon: the Vehicle for Transferable Colistin Resistance.

Snesrud E, McGann P, Chandler M.

MBio. 2018 Feb 13;9(1). pii: e02381-17. doi: 10.1128/mBio.02381-17.


Utilization trends and safety of intravenous iron replacement in pediatric specialty care: A large retrospective cohort study.

Boucher AA, Pfeiffer A, Bedel A, Young J, McGann PT.

Pediatr Blood Cancer. 2018 Jun;65(6):e26995. doi: 10.1002/pbc.26995. Epub 2018 Jan 25.


Realizing effectiveness across continents with hydroxyurea: Enrollment and baseline characteristics of the multicenter REACH study in Sub-Saharan Africa.

McGann PT, Williams TN, Olupot-Olupot P, Tomlinson GA, Lane A, Luís Reis da Fonseca J, Kitenge R, Mochamah G, Wabwire H, Stuber S, Howard TA, McElhinney K, Aygun B, Latham T, Santos B, Tshilolo L, Ware RE; REACH Investigators.

Am J Hematol. 2018 Aug;93(4):537-545. doi: 10.1002/ajh.25034. Epub 2018 Jan 27.


Changing Healthcare Service Delivery to Improve Health Outcomes For Older Adults: Opportunities Not to Be Missed.

Ling SM, McGann P.

J Am Geriatr Soc. 2018 Feb;66(2):235-238. doi: 10.1111/jgs.15254. Epub 2017 Dec 28. No abstract available.


Importation, Mitigation, and Genomic Epidemiology of Candida auris at a Large Teaching Hospital.

Lesho EP, Bronstein MZ, McGann P, Stam J, Kwak Y, Maybank R, McNamara J, Callahan M, Campbell J, Hinkle MK, Walsh EE.

Infect Control Hosp Epidemiol. 2018 Jan;39(1):53-57. doi: 10.1017/ice.2017.231. Epub 2017 Dec 6.


Simultaneous point-of-care detection of anemia and sickle cell disease in Tanzania: the RAPID study.

Smart LR, Ambrose EE, Raphael KC, Hokororo A, Kamugisha E, Tyburski EA, Lam WA, Ware RE, McGann PT.

Ann Hematol. 2018 Feb;97(2):239-246. doi: 10.1007/s00277-017-3182-8. Epub 2017 Nov 16.


Clinical Features of β-Thalassemia and Sickle Cell Disease.

McGann PT, Nero AC, Ware RE.

Adv Exp Med Biol. 2017;1013:1-26. doi: 10.1007/978-1-4939-7299-9_1.


The pressing need for point-of-care diagnostics for sickle cell disease: A review of current and future technologies.

McGann PT, Hoppe C.

Blood Cells Mol Dis. 2017 Sep;67:104-113. doi: 10.1016/j.bcmd.2017.08.010. Epub 2017 Aug 8. Review.


Consumption of Chlorhexidine and Mupirocin Across the Health System of the US Department of Defense (DOD) and the Incidence of the qacA/B and mupA Genes in the DOD Facilities of the National Capital Region.

Morgan M, McGann P, Gierhart S, Chukwuma U, Richesson D, Hinkle M, Lesho E.

Clin Infect Dis. 2017 Jun 15;64(12):1801-1802. doi: 10.1093/cid/cix276. No abstract available.


Analysis of Serial Isolates of mcr-1-Positive Escherichia coli Reveals a Highly Active ISApl1 Transposon.

Snesrud E, Ong AC, Corey B, Kwak YI, Clifford R, Gleeson T, Wood S, Whitman TJ, Lesho EP, Hinkle M, McGann P.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e00056-17. doi: 10.1128/AAC.00056-17. Print 2017 May.


Sickle cell anemia in sub-Saharan Africa: advancing the clinical paradigm through partnerships and research.

McGann PT, Hernandez AG, Ware RE.

Blood. 2017 Jan 12;129(2):155-161. doi: 10.1182/blood-2016-09-702324. Epub 2016 Nov 7. No abstract available.


Stable-Isotope Dilution HPLC-Electrospray Ionization Tandem Mass Spectrometry Method for Quantifying Hydroxyurea in Dried Blood Samples.

Marahatta A, Megaraj V, McGann PT, Ware RE, Setchell KD.

Clin Chem. 2016 Dec;62(12):1593-1601. Epub 2016 Sep 30.


Genotype-phenotype correlations in hereditary elliptocytosis and hereditary pyropoikilocytosis.

Niss O, Chonat S, Dagaonkar N, Almansoori MO, Kerr K, Rogers ZR, McGann PT, Quarmyne MO, Risinger M, Zhang K, Kalfa TA.

Blood Cells Mol Dis. 2016 Oct;61:4-9. doi: 10.1016/j.bcmd.2016.07.003. Epub 2016 Jul 17.


A Model for Transposition of the Colistin Resistance Gene mcr-1 by ISApl1.

Snesrud E, He S, Chandler M, Dekker JP, Hickman AB, McGann P, Dyda F.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6973-6976. doi: 10.1128/AAC.01457-16. Print 2016 Nov.


Better Care, Smarter Spending, Healthier Outcomes.

McGann P.

Consult Pharm. 2016;31(8):410-1. doi: 10.4140/TCP.n.2016.410. No abstract available.


Erratum for McGann et al., Escherichia coli Harboring mcr-1 and blaCTX-M on a Novel IncF Plasmid: First Report of mcr-1 in the United States.

McGann P, Snesrud E, Maybank R, Corey B, Ong AC, Clifford R, Hinkle M, Whitman T, Lesho E, Schaecher KE.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):5107. doi: 10.1128/AAC.01353-16. Print 2016 Aug. No abstract available.


In vivo efficacy of humanized high dose meropenem and comparators against Pseudomonas aeruginosa isolates producing verona integron-encoded metallo-β-lactamase (VIM).

Ghazi IM, Crandon JL, Lesho EP, McGann P, Nicolau DP.

Heliyon. 2016 Jun 16;2(6):e00121. doi: 10.1016/j.heliyon.2016.e00121. eCollection 2016 Jun.


From the Battlefield to the Bedside: Supporting Warfighter and Civilian Health With the "ART" of Whole Genome Sequencing for Antibiotic Resistance and Outbreak Investigations.

Lesho E, Lin X, Clifford R, Snesrud E, Onmus-Leone F, Appalla L, Ong A, Maybank R, Nielsen L, Kwak Y, Hinkle M, Turco J, Marin JA, Hooks S, Matthews S, Hyland S, Little J, Waterman P, McGann P.

Mil Med. 2016 Jul;181(7):621-4. doi: 10.7205/MILMED-D-15-00197.


Time to Invest in Sickle Cell Anemia as a Global Health Priority.

McGann PT.

Pediatrics. 2016 Jun;137(6). pii: e20160348. doi: 10.1542/peds.2016-0348. Epub 2016 May 4. No abstract available.


Escherichia coli Harboring mcr-1 and blaCTX-M on a Novel IncF Plasmid: First Report of mcr-1 in the United States.

McGann P, Snesrud E, Maybank R, Corey B, Ong AC, Clifford R, Hinkle M, Whitman T, Lesho E, Schaecher KE.

Antimicrob Agents Chemother. 2016 Jun 20;60(7):4420-1. doi: 10.1128/AAC.01103-16. Print 2016 Jul. No abstract available. Erratum in: Antimicrob Agents Chemother. 2016 Aug;60(8):5107.


Correlating Cleaning Thoroughness with Effectiveness and Briefly Intervening to Affect Cleaning Outcomes: How Clean Is Cleaned?

Clifford R, Sparks M, Hosford E, Ong A, Richesson D, Fraser S, Kwak Y, Miller S, Julius M, McGann P, Lesho E.

PLoS One. 2016 May 19;11(5):e0155779. doi: 10.1371/journal.pone.0155779. eCollection 2016.


The Challenges of Implementing Next Generation Sequencing Across a Large Healthcare System, and the Molecular Epidemiology and Antibiotic Susceptibilities of Carbapenemase-Producing Bacteria in the Healthcare System of the U.S. Department of Defense.

Lesho E, Clifford R, Onmus-Leone F, Appalla L, Snesrud E, Kwak Y, Ong A, Maybank R, Waterman P, Rohrbeck P, Julius M, Roth A, Martinez J, Nielsen L, Steele E, McGann P, Hinkle M.

PLoS One. 2016 May 19;11(5):e0155770. doi: 10.1371/journal.pone.0155770. eCollection 2016.


Real time application of whole genome sequencing for outbreak investigation - What is an achievable turnaround time?

McGann P, Bunin JL, Snesrud E, Singh S, Maybank R, Ong AC, Kwak YI, Seronello S, Clifford RJ, Hinkle M, Yamada S, Barnhill J, Lesho E.

Diagn Microbiol Infect Dis. 2016 Jul;85(3):277-282. doi: 10.1016/j.diagmicrobio.2016.04.020. Epub 2016 Apr 30.


Hydroxyurea for abnormal TCDs: safe to switch?

McGann PT.

Blood. 2016 Apr 7;127(14):1738-40. doi: 10.1182/blood-2016-02-699074.


Improving survival for children with sickle cell disease: newborn screening is only the first step.

McGann PT.

Paediatr Int Child Health. 2015;35(4):285-6. doi: 10.1080/20469047.2015.1109255.


Development of a pharmacokinetic-guided dose individualization strategy for hydroxyurea treatment in children with sickle cell anaemia.

Dong M, McGann PT, Mizuno T, Ware RE, Vinks AA.

Br J Clin Pharmacol. 2016 Apr;81(4):742-52. doi: 10.1111/bcp.12851. Epub 2016 Feb 5.


Characteristics of a rapid, point-of-care lateral flow immunoassay for the diagnosis of sickle cell disease.

McGann PT, Schaefer BA, Paniagua M, Howard TA, Ware RE.

Am J Hematol. 2016 Feb;91(2):205-10. doi: 10.1002/ajh.24232. Epub 2015 Nov 26.


Detecting 16S rRNA Methyltransferases in Enterobacteriaceae by Use of Arbekacin.

McGann P, Chahine S, Okafor D, Ong AC, Maybank R, Kwak YI, Wilson K, Zapor M, Lesho E, Hinkle M.

J Clin Microbiol. 2016 Jan;54(1):208-11. doi: 10.1128/JCM.02642-15. Epub 2015 Nov 4.

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