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Items: 7


MAP kinase phosphatase-2 plays a key role in the control of infection with Toxoplasma gondii by modulating iNOS and arginase-1 activities in mice.

Woods S, Schroeder J, McGachy HA, Plevin R, Roberts CW, Alexander J.

PLoS Pathog. 2013 Aug;9(8):e1003535. doi: 10.1371/journal.ppat.1003535. Epub 2013 Aug 15.


T cell hypo-responsiveness against Leishmania major in MAP kinase phosphatase (MKP) 2 deficient C57BL/6 mice does not alter the healer disease phenotype.

Schroeder J, McGachy HA, Woods S, Plevin R, Alexander J.

PLoS Negl Trop Dis. 2013;7(2):e2064. doi: 10.1371/journal.pntd.0002064. Epub 2013 Feb 21.


BALB/c mice deficient in CD4 T cell IL-4Rα expression control Leishmania mexicana Load although female but not male mice develop a healer phenotype.

Bryson KJ, Millington OR, Mokgethi T, McGachy HA, Brombacher F, Alexander J.

PLoS Negl Trop Dis. 2011 Jan 4;5(1):e930. doi: 10.1371/journal.pntd.0000930.


MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.

Al-Mutairi MS, Cadalbert LC, McGachy HA, Shweash M, Schroeder J, Kurnik M, Sloss CM, Bryant CE, Alexander J, Plevin R.

PLoS Pathog. 2010 Nov 11;6(11):e1001192. doi: 10.1371/journal.ppat.1001192.


Overexpression of the natural inhibitor of cysteine peptidases in Leishmania mexicana leads to reduced virulence and a Th1 response.

Bryson K, Besteiro S, McGachy HA, Coombs GH, Mottram JC, Alexander J.

Infect Immun. 2009 Jul;77(7):2971-8. doi: 10.1128/IAI.00558-08. Epub 2009 May 11.


An essential role for IL-13 in maintaining a non-healing response following Leishmania mexicana infection.

Alexander J, Brombacher F, McGachy HA, McKenzie AN, Walker W, Carter KC.

Eur J Immunol. 2002 Oct;32(10):2923-33.

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