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Items: 21

1.

Structural and functional analysis of the GABARAP interaction motif (GIM).

Rogov VV, Stolz A, Ravichandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Löhr F, Wakatsuki S, Dötsch V, Dikic I, Dobson RC, McEwan DG.

EMBO Rep. 2018 Dec;19(12). pii: e47268. doi: 10.15252/embr.201847268. No abstract available.

2.

Host-pathogen interactions and subversion of autophagy.

McEwan DG.

Essays Biochem. 2017 Dec 12;61(6):687-697. doi: 10.1042/EBC20170058. Print 2017 Dec 12. Review.

3.

Structural and functional analysis of the GABARAP interaction motif (GIM).

Rogov VV, Stolz A, Ravichandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Löhr F, Wakatsuki S, Dötsch V, Dikic I, Dobson RC, McEwan DG.

EMBO Rep. 2017 Aug;18(8):1382-1396. doi: 10.15252/embr.201643587. Epub 2017 Jun 27. Erratum in: EMBO Rep. 2018 Dec;19(12):.

4.

Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation.

Habisov S, Huber J, Ichimura Y, Akutsu M, Rogova N, Loehr F, McEwan DG, Johansen T, Dikic I, Doetsch V, Komatsu M, Rogov VV, Kirkin V.

J Biol Chem. 2016 Apr 22;291(17):9025-41. doi: 10.1074/jbc.M116.715474. Epub 2016 Feb 29.

5.

Rab7a and Rab27b control secretion of endothelial microRNA through extracellular vesicles.

Jaé N, McEwan DG, Manavski Y, Boon RA, Dimmeler S.

FEBS Lett. 2015 Oct 7;589(20 Pt B):3182-8. doi: 10.1016/j.febslet.2015.08.040. Epub 2015 Sep 5.

6.

PLEKHM1: Adapting to life at the lysosome.

McEwan DG, Dikic I.

Autophagy. 2015 Apr 3;11(4):720-2. doi: 10.1080/15548627.2015.1034419.

7.

Cullins keep autophagy under control.

McEwan DG, Dikic I.

Dev Cell. 2014 Dec 22;31(6):675-6. doi: 10.1016/j.devcel.2014.12.010.

8.

PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.

McEwan DG, Richter B, Claudi B, Wigge C, Wild P, Farhan H, McGourty K, Coxon FP, Franz-Wachtel M, Perdu B, Akutsu M, Habermann A, Kirchof A, Helfrich MH, Odgren PR, Van Hul W, Frangakis AS, Rajalingam K, Macek B, Holden DW, Bumann D, Dikic I.

Cell Host Microbe. 2015 Jan 14;17(1):58-71. doi: 10.1016/j.chom.2014.11.011. Epub 2014 Dec 11.

9.

PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.

McEwan DG, Popovic D, Gubas A, Terawaki S, Suzuki H, Stadel D, Coxon FP, Miranda de Stegmann D, Bhogaraju S, Maddi K, Kirchof A, Gatti E, Helfrich MH, Wakatsuki S, Behrends C, Pierre P, Dikic I.

Mol Cell. 2015 Jan 8;57(1):39-54. doi: 10.1016/j.molcel.2014.11.006. Epub 2014 Dec 11.

10.

The LC3 interactome at a glance.

Wild P, McEwan DG, Dikic I.

J Cell Sci. 2014 Jan 1;127(Pt 1):3-9. doi: 10.1242/jcs.140426. Epub 2013 Dec 17. Review.

11.

Structural basis for phosphorylation-triggered autophagic clearance of Salmonella.

Rogov VV, Suzuki H, Fiskin E, Wild P, Kniss A, Rozenknop A, Kato R, Kawasaki M, McEwan DG, Löhr F, Güntert P, Dikic I, Wakatsuki S, Dötsch V.

Biochem J. 2013 Sep 15;454(3):459-66.

PMID:
23805866
12.

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling.

Sandilands E, Serrels B, McEwan DG, Morton JP, Macagno JP, McLeod K, Stevens C, Brunton VG, Langdon WY, Vidal M, Sansom OJ, Dikic I, Wilkinson S, Frame MC.

Nat Cell Biol. 2011 Dec 4;14(1):51-60. doi: 10.1038/ncb2386.

PMID:
22138575
13.

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth.

Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady NR, Richter B, Korac J, Waidmann O, Choudhary C, Dötsch V, Bumann D, Dikic I.

Science. 2011 Jul 8;333(6039):228-33. doi: 10.1126/science.1205405. Epub 2011 May 26.

14.

The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation.

McEwan DG, Dikic I.

Trends Cell Biol. 2011 Apr;21(4):195-201. doi: 10.1016/j.tcb.2010.12.006. Epub 2011 Jan 27.

15.

Not all autophagy membranes are created equal.

McEwan DG, Dikic I.

Cell. 2010 May 14;141(4):564-6. doi: 10.1016/j.cell.2010.04.030.

16.

Nix is a selective autophagy receptor for mitochondrial clearance.

Novak I, Kirkin V, McEwan DG, Zhang J, Wild P, Rozenknop A, Rogov V, Löhr F, Popovic D, Occhipinti A, Reichert AS, Terzic J, Dötsch V, Ney PA, Dikic I.

EMBO Rep. 2010 Jan;11(1):45-51. doi: 10.1038/embor.2009.256. Epub 2009 Dec 11.

17.

A role for ubiquitin in selective autophagy.

Kirkin V, McEwan DG, Novak I, Dikic I.

Mol Cell. 2009 May 15;34(3):259-69. doi: 10.1016/j.molcel.2009.04.026. Review.

18.

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.

Kirkin V, Lamark T, Sou YS, Bjørkøy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Øvervatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T.

Mol Cell. 2009 Feb 27;33(4):505-16. doi: 10.1016/j.molcel.2009.01.020.

19.

Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors.

Sandilands E, Akbarzadeh S, Vecchione A, McEwan DG, Frame MC, Heath JK.

EMBO Rep. 2007 Dec;8(12):1162-9. Epub 2007 Nov 2.

20.
21.

Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2.

Bolger GB, Peden AH, Steele MR, MacKenzie C, McEwan DG, Wallace DA, Huston E, Baillie GS, Houslay MD.

J Biol Chem. 2003 Aug 29;278(35):33351-63. Epub 2003 Jun 16.

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