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Items: 30


Fetal exposure to maternal inflammation interrupts murine intestinal development and increases susceptibility to neonatal intestinal injury.

Elgin TG, Fricke EM, Gong H, Reese J, Mills DA, Kalantera KM, Underwood MA, McElroy SJ.

Dis Model Mech. 2019 Oct 21;12(10). pii: dmm040808. doi: 10.1242/dmm.040808.


A direct comparison of mouse and human intestinal development using epithelial gene expression patterns.

Stanford AH, Gong H, Noonan M, Lewis AN, Gong Q, Lanik WE, Hsieh JJ, Lueschow SR, Frey MR, Good M, McElroy SJ.

Pediatr Res. 2019 Jun 26. doi: 10.1038/s41390-019-0472-y. [Epub ahead of print]


Dithizone-induced Paneth cell disruption significantly decreases intestinal perfusion in the murine small intestine.

Berger JN, Gong H, Good M, McElroy SJ.

J Pediatr Surg. 2019 Feb 23. pii: S0022-3468(19)30138-1. doi: 10.1016/j.jpedsurg.2019.02.021. [Epub ahead of print]


Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis.

Lueschow SR, Stumphy J, Gong H, Kern SL, Elgin TG, Underwood MA, Kalanetra KM, Mills DA, Wong MH, Meyerholz DK, Good M, McElroy SJ.

PLoS One. 2018 Oct 1;13(10):e0204967. doi: 10.1371/journal.pone.0204967. eCollection 2018.


Limited achievement of NIH research independence by pediatric K award recipients.

Good M, McElroy SJ, Berger JN, Moore DJ, Wynn JL.

Pediatr Res. 2018 Oct;84(4):479-480. doi: 10.1038/s41390-018-0056-2. Epub 2018 Jun 14. No abstract available.


Lipopolysaccharide-induced maternal inflammation induces direct placental injury without alteration in placental blood flow and induces a secondary fetal intestinal injury that persists into adulthood.

Fricke EM, Elgin TG, Gong H, Reese J, Gibson-Corley KN, Weiss RM, Zimmerman K, Bowdler NC, Kalantera KM, Mills DA, Underwood MA, McElroy SJ.

Am J Reprod Immunol. 2018 May;79(5):e12816. doi: 10.1111/aji.12816. Epub 2018 Jan 25.


Name and Characteristics of National Institutes of Health R01-Funded Pediatric Physician-Scientists: Hope and Challenges for the Vanishing Pediatric Physician-Scientists.

Good M, McElroy SJ, Berger JN, Wynn JL.

JAMA Pediatr. 2018 Mar 1;172(3):297-299. doi: 10.1001/jamapediatrics.2017.4947. No abstract available.


The science and necessity of using animal models in the study of necrotizing enterocolitis.

Ares GJ, McElroy SJ, Hunter CJ.

Semin Pediatr Surg. 2018 Feb;27(1):29-33. doi: 10.1053/j.sempedsurg.2017.11.006. Epub 2017 Nov 6. Review.


Jack Widness: the importance of connections.

McElroy SJ.

Pediatr Res. 2018 Apr;83(4):757-759. doi: 10.1038/pr.2017.317. Epub 2018 Jan 10. No abstract available.


Intraoperative High-Frequency Jet Ventilation Is Equivalent to Conventional Ventilation During Patent Ductus Arteriosus Ligation.

Noonan M, Turek JW, Dagle JM, McElroy SJ.

World J Pediatr Congenit Heart Surg. 2017 Sep;8(5):570-574. doi: 10.1177/2150135117717974.


Paneth-cell-disruption-induced necrotizing enterocolitis in mice requires live bacteria and occurs independently of TLR4 signaling.

White JR, Gong H, Pope B, Schlievert P, McElroy SJ.

Dis Model Mech. 2017 Jun 1;10(6):727-736. doi: 10.1242/dmm.028589. Epub 2017 Apr 27.


Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18.

Wynn JL, Wilson CS, Hawiger J, Scumpia PO, Marshall AF, Liu JH, Zharkikh I, Wong HR, Lahni P, Benjamin JT, Plosa EJ, Weitkamp JH, Sherwood ER, Moldawer LL, Ungaro R, Baker HV, Lopez MC, McElroy SJ, Colliou N, Mohamadzadeh M, Moore DJ.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2627-35. doi: 10.1073/pnas.1515793113. Epub 2016 Apr 25.


Development of the Neonatal Intestinal Microbiome and Its Association With Necrotizing Enterocolitis.

Elgin TG, Kern SL, McElroy SJ.

Clin Ther. 2016 Apr;38(4):706-15. doi: 10.1016/j.clinthera.2016.01.005. Epub 2016 Feb 3. Review.


Intrauterine Growth Restriction Alters Mouse Intestinal Architecture during Development.

Fung CM, White JR, Brown AS, Gong H, Weitkamp JH, Frey MR, McElroy SJ.

PLoS One. 2016 Jan 8;11(1):e0146542. doi: 10.1371/journal.pone.0146542. eCollection 2016.


Evaluation of hematologic variables in newborn C57/BL6 mice up to day 35.

White JR, Gong H, Colaizy TT, Moreland JG, Flaherty H, McElroy SJ.

Vet Clin Pathol. 2016 Mar;45(1):87-95. doi: 10.1111/vcp.12314. Epub 2015 Dec 30.


The Role of Bacteria in Necrotizing Enterocolitis: Understanding the Forest for the Trees.

McElroy SJ.

Neonatology. 2015;108(3):196-7. doi: 10.1159/000437205. Epub 2015 Aug 7. No abstract available.


Unraveling the enigma that is neonatal necrotizing enterocolitis.

McElroy SJ.

J Perinatol. 2014 Oct;34(10):729-30. doi: 10.1038/jp.2014.155. No abstract available.


Tumor necrosis factor induces developmental stage-dependent structural changes in the immature small intestine.

Brown KS, Gong H, Frey MR, Pope B, Golden M, Martin K, Obey M, McElroy SJ.

Mediators Inflamm. 2014;2014:852378. doi: 10.1155/2014/852378. Epub 2014 Aug 27.


The ErbB4 ligand neuregulin-4 protects against experimental necrotizing enterocolitis.

McElroy SJ, Castle SL, Bernard JK, Almohazey D, Hunter CJ, Bell BA, Al Alam D, Wang L, Ford HR, Frey MR.

Am J Pathol. 2014 Oct;184(10):2768-78. doi: 10.1016/j.ajpath.2014.06.015. Epub 2014 Sep 9.


Correlation of abdominal rSO2 with superior mesenteric artery velocities in preterm infants.

Gillam-Krakauer M, Cochran CM, Slaughter JC, Polavarapu S, McElroy SJ, Hernanz-Schulman M, Engelhardt B.

J Perinatol. 2013 Aug;33(8):609-12. doi: 10.1038/jp.2013.3. Epub 2013 Feb 7.


Paneth cells and necrotizing enterocolitis: a novel hypothesis for disease pathogenesis.

McElroy SJ, Underwood MA, Sherman MP.

Neonatology. 2013;103(1):10-20. doi: 10.1159/000342340. Epub 2012 Sep 20. Review.


Epidermal growth factor receptor inhibits colitis-associated cancer in mice.

Dubé PE, Yan F, Punit S, Girish N, McElroy SJ, Washington MK, Polk DB.

J Clin Invest. 2012 Aug;122(8):2780-92. doi: 10.1172/JCI62888. Epub 2012 Jul 9.


Transactivation of EGFR by LPS induces COX-2 expression in enterocytes.

McElroy SJ, Hobbs S, Kallen M, Tejera N, Rosen MJ, Grishin A, Matta P, Schneider C, Upperman J, Ford H, Polk DB, Weitkamp JH.

PLoS One. 2012;7(5):e38373. doi: 10.1371/journal.pone.0038373. Epub 2012 May 31.


Innate Immunity in the Small Intestine of the Preterm Infant.

McElroy SJ, Weitkamp JH.

Neoreviews. 2011 Sep 1;12(9):e517-e526.


Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature mice.

Zhang C, Sherman MP, Prince LS, Bader D, Weitkamp JH, Slaughter JC, McElroy SJ.

Dis Model Mech. 2012 Jul;5(4):522-32. doi: 10.1242/dmm.009001. Epub 2012 Feb 10.


Tumor necrosis factor receptor 1-dependent depletion of mucus in immature small intestine: a potential role in neonatal necrotizing enterocolitis.

McElroy SJ, Prince LS, Weitkamp JH, Reese J, Slaughter JC, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G656-66. doi: 10.1152/ajpgi.00550.2010. Epub 2011 Jul 7.


TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB.

Edelblum KL, Goettel JA, Koyama T, McElroy SJ, Yan F, Polk DB.

J Biol Chem. 2008 Oct 24;283(43):29485-94. doi: 10.1074/jbc.M801269200. Epub 2008 Aug 18.


Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism.

McElroy SJ, Frey MR, Yan F, Edelblum KL, Goettel JA, John S, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2008 Aug;295(2):G285-93. doi: 10.1152/ajpgi.00425.2007. Epub 2008 May 8.


Foley catheter tamponade of intercostal hemorrhage in preterm infants.

McElroy SJ, Pietsch JB, Reese J.

J Pediatr. 2004 Aug;145(2):241. No abstract available.


Enhanced skill building.

Streeter KJ, McElroy SJ, Zarro V.

Acad Med. 1997 May;72(5):438. No abstract available.


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