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Items: 29

1.

Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.

Bohn JA, Van Etten JL, Schagat TL, Bowman BM, McEachin RC, Freddolino PL, Goldstrohm AC.

Nucleic Acids Res. 2018 Jan 9;46(1):362-386. doi: 10.1093/nar/gkx1120.

2.

Group B streptococcus activates transcriptomic pathways related to premature birth in human extraplacental membranes in vitro.

Park HR, Harris SM, Boldenow E, McEachin RC, Sartor M, Chames M, Loch-Caruso R.

Biol Reprod. 2018 Mar 1;98(3):396-407. doi: 10.1093/biolre/iox147.

3.

A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.

Ramani B, Harris GM, Huang R, Seki T, Murphy GG, Carmo Costa MD, Fischer S, Saunders TL, Xia G, McEachin RC, Paulson HL.

Hum Mol Genet. 2017 Aug 15;26(16):3232-3233. doi: 10.1093/hmg/ddx176. No abstract available.

4.

Canalization Leads to Similar Whole Bone Mechanical Function at Maturity in Two Inbred Strains of Mice.

Schlecht SH, Smith LM, Ramcharan MA, Bigelow EM, Nolan BT, Mathis NJ, Cathey A, Manley E Jr, Menon R, McEachin RC, Nadeau JH, Jepsen KJ.

J Bone Miner Res. 2017 May;32(5):1002-1013. doi: 10.1002/jbmr.3093. Epub 2017 Feb 27.

5.

Developmental programming: Interaction between prenatal BPA and postnatal overfeeding on cardiac tissue gene expression in female sheep.

Koneva LA, Vyas AK, McEachin RC, Puttabyatappa M, Wang HS, Sartor MA, Padmanabhan V.

Environ Mol Mutagen. 2017 Jan;58(1):4-18. doi: 10.1002/em.22071. Epub 2017 Jan 12.

6.

Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas.

Bayliss J, Mukherjee P, Lu C, Jain SU, Chung C, Martinez D, Sabari B, Margol AS, Panwalkar P, Parolia A, Pekmezci M, McEachin RC, Cieslik M, Tamrazi B, Garcia BA, La Rocca G, Santi M, Lewis PW, Hawkins C, Melnick A, David Allis C, Thompson CB, Chinnaiyan AM, Judkins AR, Venneti S.

Sci Transl Med. 2016 Nov 23;8(366):366ra161.

7.

Bisphenol A-associated alterations in genome-wide DNA methylation and gene expression patterns reveal sequence-dependent and non-monotonic effects in human fetal liver.

Faulk C, Kim JH, Jones TR, McEachin RC, Nahar MS, Dolinoy DC, Sartor MA.

Environ Epigenet. 2015 Dec;1(1). pii: dvv006. Epub 2015 Jan 1.

8.

Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegans.

Chen AT, Guo C, Itani OA, Budaitis BG, Williams TW, Hopkins CE, McEachin RC, Pande M, Grant AR, Yoshina S, Mitani S, Hu PJ.

Genetics. 2015 Oct;201(2):613-29. doi: 10.1534/genetics.115.177998. Epub 2015 Jul 27.

9.

Reversal of the Transcriptome by Prostaglandin E2 during Myofibroblast Dedifferentiation.

Wettlaufer SH, Scott JP, McEachin RC, Peters-Golden M, Huang SK.

Am J Respir Cell Mol Biol. 2016 Jan;54(1):114-27. doi: 10.1165/rcmb.2014-0468OC.

10.

Blunted cardiomyocyte remodeling response in exercise-resistant rats.

Wisløff U, Bye A, Stølen T, Kemi OJ, Pollott GE, Pande M, McEachin RC, Britton SL, Koch LG.

J Am Coll Cardiol. 2015 Apr 7;65(13):1378-1380. doi: 10.1016/j.jacc.2015.01.041. No abstract available.

11.

Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.

Chua JP, Reddy SL, Yu Z, Giorgetti E, Montie HL, Mukherjee S, Higgins J, McEachin RC, Robins DM, Merry DE, Iñiguez-Lluhí JA, Lieberman AP.

J Clin Invest. 2015 Feb;125(2):831-45. doi: 10.1172/JCI73214. Epub 2015 Jan 20.

12.

A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.

Ramani B, Harris GM, Huang R, Seki T, Murphy GG, Costa Mdo C, Fischer S, Saunders TL, Xia G, McEachin RC, Paulson HL.

Hum Mol Genet. 2015 Mar 1;24(5):1211-24. doi: 10.1093/hmg/ddu532. Epub 2014 Oct 15. Erratum in: Hum Mol Genet. 2017 Aug 15;26(16):3232-3233.

13.

Lung fibroblasts from patients with idiopathic pulmonary fibrosis exhibit genome-wide differences in DNA methylation compared to fibroblasts from nonfibrotic lung.

Huang SK, Scruggs AM, McEachin RC, White ES, Peters-Golden M.

PLoS One. 2014 Sep 12;9(9):e107055. doi: 10.1371/journal.pone.0107055. eCollection 2014.

14.

A bioinformatics approach reveals novel interactions of the OVOL transcription factors in the regulation of epithelial - mesenchymal cell reprogramming and cancer progression.

Roca H, Pande M, Huo JS, Hernandez J, Cavalcoli JD, Pienta KJ, McEachin RC.

BMC Syst Biol. 2014 Mar 10;8:29. doi: 10.1186/1752-0509-8-29.

15.

H2A.B facilitates transcription elongation at methylated CpG loci.

Chen Y, Chen Q, McEachin RC, Cavalcoli JD, Yu X.

Genome Res. 2014 Apr;24(4):570-9. doi: 10.1101/gr.156877.113. Epub 2014 Jan 8.

16.

Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer.

Roca H, Hernandez J, Weidner S, McEachin RC, Fuller D, Sud S, Schumann T, Wilkinson JE, Zaslavsky A, Li H, Maher CA, Daignault-Newton S, Healy PN, Pienta KJ.

PLoS One. 2013 Oct 4;8(10):e76773. doi: 10.1371/journal.pone.0076773. eCollection 2013.

17.

Prostaglandin E₂ increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression.

Huang SK, Scruggs AM, Donaghy J, McEachin RC, Fisher AS, Richardson BC, Peters-Golden M.

FASEB J. 2012 Sep;26(9):3703-14. doi: 10.1096/fj.11-203323. Epub 2012 May 29.

18.

Convergence of genetic influences in comorbidity.

McEachin RC, Sannareddy KS, Cavalcoli JD, Karnovsky A, Vink JM, Sartor MA.

BMC Bioinformatics. 2012 Mar 13;13 Suppl 2:S8. doi: 10.1186/1471-2105-13-S2-S8.

19.

A genetic network model of cellular responses to lithium treatment and cocaine abuse in bipolar disorder.

McEachin RC, Chen H, Sartor MA, Saccone SF, Keller BJ, Prossin AR, Cavalcoli JD, McInnis MG.

BMC Syst Biol. 2010 Nov 19;4:158. doi: 10.1186/1752-0509-4-158.

20.

Modeling complex genetic and environmental influences on comorbid bipolar disorder with tobacco use disorder.

McEachin RC, Saccone NL, Saccone SF, Kleyman-Smith YD, Kar T, Kare RK, Ade AS, Sartor MA, Cavalcoli JD, McInnis MG.

BMC Med Genet. 2010 Jan 26;11:14. doi: 10.1186/1471-2350-11-14.

21.

Identifying hypothetical genetic influences on complex disease phenotypes.

Keller BJ, McEachin RC.

BMC Bioinformatics. 2009 Feb 5;10 Suppl 2:S13. doi: 10.1186/1471-2105-10-S2-S13.

22.

Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics approach.

McEachin RC, Keller BJ, Saunders EF, McInnis MG.

BioData Min. 2008 Jul 17;1(1):2. doi: 10.1186/1756-0381-1-2.

23.

Prioritizing Disease Genes by Analysis of Common Elements (PDG-ACE).

McEachin RC, Keller BJ, Zandi PP, Almani M, McInnis MG.

AMIA Annu Symp Proc. 2007 Oct 11:1068.

PMID:
18694166
24.

Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans.

Black MH, Fingerlin TE, Allayee H, Zhang W, Xiang AH, Trigo E, Hartiala J, Lehtinen AB, Haffner SM, Bergman RN, McEachin RC, Kjos SL, Lawrence JM, Buchanan TA, Watanabe RM.

Diabetes. 2008 Apr;57(4):1048-56. Epub 2007 Dec 27.

25.

SAGA: a subgraph matching tool for biological graphs.

Tian Y, McEachin RC, Santos C, States DJ, Patel JM.

Bioinformatics. 2007 Jan 15;23(2):232-9. Epub 2006 Nov 16.

PMID:
17110368
26.

SNP Function Portal: a web database for exploring the function implication of SNP alleles.

Wang P, Dai M, Xuan W, McEachin RC, Jackson AU, Scott LJ, Athey B, Watson SJ, Meng F.

Bioinformatics. 2006 Jul 15;22(14):e523-9.

PMID:
16873516
27.

Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH.

Huo JS, McEachin RC, Cui TX, Duggal NK, Hai T, States DJ, Schwartz J.

J Biol Chem. 2006 Feb 17;281(7):4132-41. Epub 2005 Dec 1.

28.

Computationally identifying novel NF-kappa B-regulated immune genes in the human genome.

Liu R, McEachin RC, States DJ.

Genome Res. 2003 Apr;13(4):654-61. Epub 2003 Mar 12.

29.

The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci.

Watanabe RM, Ghosh S, Langefeld CD, Valle TT, Hauser ER, Magnuson VL, Mohlke KL, Silander K, Ally DS, Chines P, Blaschak-Harvan J, Douglas JA, Duren WL, Epstein MP, Fingerlin TE, Kaleta HS, Lange EM, Li C, McEachin RC, Stringham HM, Trager E, White PP, Balow J Jr, Birznieks G, Chang J, Eldridge W.

Am J Hum Genet. 2000 Nov;67(5):1186-200. Epub 2000 Oct 13.

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