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Items: 43

1.

Chromosome ends as adaptive beginnings: the potential role of dysfunctional telomeres in subtelomeric evolvability.

Mason JMO, McEachern MJ.

Curr Genet. 2018 Oct;64(5):997-1000. doi: 10.1007/s00294-018-0822-z. Epub 2018 Mar 27. Review.

PMID:
29589105
2.

Mild Telomere Dysfunction as a Force for Altering the Adaptive Potential of Subtelomeric Genes.

Mason JMO, McEachern MJ.

Genetics. 2018 Feb;208(2):537-548. doi: 10.1534/genetics.117.300607. Epub 2017 Dec 14.

3.

Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scrambling.

Xu J, McEachern MJ.

PLoS Genet. 2012;8(11):e1003017. doi: 10.1371/journal.pgen.1003017. Epub 2012 Nov 1.

5.

Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance.

Hsu M, Yu EY, Sprušanský O, McEachern MJ, Lue NF.

Eukaryot Cell. 2012 Jul;11(7):932-42. doi: 10.1128/EC.05319-11. Epub 2012 Apr 27.

6.

Recombination can either help maintain very short telomeres or generate longer telomeres in yeast cells with weak telomerase activity.

Basenko E, Topcu Z, McEachern MJ.

Eukaryot Cell. 2011 Aug;10(8):1131-42. doi: 10.1128/EC.05079-11. Epub 2011 Jun 10.

7.

Recombination can cause telomere elongations as well as truncations deep within telomeres in wild-type Kluyveromyces lactis cells.

Bechard LH, Jamieson N, McEachern MJ.

Eukaryot Cell. 2011 Feb;10(2):226-36. doi: 10.1128/EC.00209-10. Epub 2010 Dec 10.

8.

Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination.

Basenko EY, Cesare AJ, Iyer S, Griffith JD, McEachern MJ.

Nucleic Acids Res. 2010 Jan;38(1):182-9. doi: 10.1093/nar/gkp814. Epub 2009 Oct 25.

9.

Evidence for an additional base-pairing element between the telomeric repeat and the telomerase RNA template in Kluyveromyces lactis and other yeasts.

Wang ZR, Guo L, Chen L, McEachern MJ.

Mol Cell Biol. 2009 Oct;29(20):5389-98. doi: 10.1128/MCB.00528-09. Epub 2009 Aug 17.

10.

Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype.

Bechard LH, Butuner BD, Peterson GJ, McRae W, Topcu Z, McEachern MJ.

Mol Cell Biol. 2009 Feb;29(3):626-39. doi: 10.1128/MCB.00423-08. Epub 2008 Nov 24.

11.

Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain.

Cesare AJ, Groff-Vindman C, Compton SA, McEachern MJ, Griffith JD.

Mol Cell Biol. 2008 Jan;28(1):20-9. Epub 2007 Oct 29.

12.

Telomerase core components protect Candida telomeres from aberrant overhang accumulation.

Hsu M, McEachern MJ, Dandjinou AT, Tzfati Y, Orr E, Blackburn EH, Lue NF.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11682-7. Epub 2007 Jul 3.

13.

The role of nonhomologous end-joining components in telomere metabolism in Kluyveromyces lactis.

Carter SD, Iyer S, Xu J, McEachern MJ, Aström SU.

Genetics. 2007 Mar;175(3):1035-45. Epub 2007 Jan 21.

14.

Break-induced replication and recombinational telomere elongation in yeast.

McEachern MJ, Haber JE.

Annu Rev Biochem. 2006;75:111-35. Review.

PMID:
16756487
15.

Screening for telomeric recombination in wild-type Kluyveromyces lactis.

Natarajan S, Nickles K, McEachern MJ.

FEMS Yeast Res. 2006 May;6(3):442-8.

17.

Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles.

Groff-Vindman C, Cesare AJ, Natarajan S, Griffith JD, McEachern MJ.

Mol Cell Biol. 2005 Jun;25(11):4406-12.

18.

Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis.

Topcu Z, Nickles K, Davis C, McEachern MJ.

Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3348-53. Epub 2005 Feb 15.

20.

Alternatives to telomerase: keeping linear chromosomes via telomeric circles.

Tomaska L, McEachern MJ, Nosek J.

FEBS Lett. 2004 Jun 1;567(1):142-6. Review.

21.

A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length.

Askree SH, Yehuda T, Smolikov S, Gurevich R, Hawk J, Coker C, Krauskopf A, Kupiec M, McEachern MJ.

Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8658-63. Epub 2004 May 25.

22.
23.

Template requirements for telomerase translocation in Kluyveromyces lactis.

Underwood DH, Zinzen RP, McEachern MJ.

Mol Cell Biol. 2004 Jan;24(2):912-23.

24.

Factors influencing the recombinational expansion and spread of telomeric tandem arrays in Kluyveromyces lactis.

Natarajan S, Groff-Vindman C, McEachern MJ.

Eukaryot Cell. 2003 Oct;2(5):1115-27.

25.

Recombinational telomere elongation promoted by DNA circles.

Natarajan S, McEachern MJ.

Mol Cell Biol. 2002 Jul;22(13):4512-21.

26.

Dynamics of telomeric DNA turnover in yeast.

McEachern MJ, Underwood DH, Blackburn EH.

Genetics. 2002 Jan;160(1):63-73.

27.

Totally mutant telomeres: single-step mutagenesis of tandem repeat DNA sequences.

Underwood DH, McEachern MJ.

Biotechniques. 2001 May;30(5):934-5, 938. No abstract available.

28.

Short telomeres in yeast are highly recombinogenic.

McEachern MJ, Iyer S.

Mol Cell. 2001 Apr;7(4):695-704.

29.

Telomeres and their control.

McEachern MJ, Krauskopf A, Blackburn EH.

Annu Rev Genet. 2000;34:331-358. Review.

PMID:
11092831
30.

Telomere fusions caused by mutating the terminal region of telomeric DNA.

McEachern MJ, Iyer S, Fulton TB, Blackburn EH.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11409-14.

31.

Telomeric sequence diversity within the genus Saccharomyces.

Cohn M, McEachern MJ, Blackburn EH.

Curr Genet. 1998 Feb;33(2):83-91.

PMID:
9506895
33.

Runaway telomere elongation caused by telomerase RNA gene mutations.

McEachern MJ, Blackburn EH.

Nature. 1995 Aug 3;376(6539):403-9.

PMID:
7630414
34.

A conserved sequence motif within the exceptionally diverse telomeric sequences of budding yeasts.

McEachern MJ, Blackburn EH.

Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3453-7.

35.

Unusually large telomeric repeats in the yeast Candida albicans.

McEachern MJ, Hicks JB.

Mol Cell Biol. 1993 Jan;13(1):551-60.

38.

Telomeric and dispersed repeat sequences in Candida yeasts and their use in strain identification.

Sadhu C, McEachern MJ, Rustchenko-Bulgac EP, Schmid J, Soll DR, Hicks JB.

J Bacteriol. 1991 Jan;173(2):842-50.

39.

N-terminal truncated forms of the bifunctional pi initiation protein express negative activity on plasmid R6K replication.

Greener A, Filutowicz MS, McEachern MJ, Helinski DR.

Mol Gen Genet. 1990 Oct;224(1):24-32.

PMID:
2277631
40.

Negative control of plasmid R6K replication: possible role of intermolecular coupling of replication origins.

McEachern MJ, Bott MA, Tooker PA, Helinski DR.

Proc Natl Acad Sci U S A. 1989 Oct;86(20):7942-6.

41.

DNA and protein interactions in the regulation of plasmid replication.

Filutowicz M, McEachern MJ, Mukhopadhyay P, Greener A, Yang SL, Helinski DR.

J Cell Sci Suppl. 1987;7:15-31.

PMID:
3332651
42.

Positive and negative roles of an initiator protein at an origin of replication.

Filutowicz M, McEachern MJ, Helinski DR.

Proc Natl Acad Sci U S A. 1986 Dec;83(24):9645-9.

43.

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