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Items: 1 to 50 of 204

1.

Human genome-wide measurement of drug-responsive regulatory activity.

Johnson GD, Barrera A, McDowell IC, D'Ippolito AM, Majoros WH, Vockley CM, Wang X, Allen AS, Reddy TE.

Nat Commun. 2018 Dec 21;9(1):5317. doi: 10.1038/s41467-018-07607-x.

2.

Coronary heart disease mortality in severe vs. non-severe familial hypercholesterolaemia in the Simon Broome Register.

Humphries SE, Cooper JA, Capps N, Durrington PN, Jones B, McDowell IFW, Soran H, Neil AHW; Simon Broome Familial Hyperlipidaemia Register Group.

Atherosclerosis. 2019 Feb;281:207-212. doi: 10.1016/j.atherosclerosis.2018.11.014. Epub 2018 Nov 12.

3.

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding.

McDowell IC, Barrera A, D'Ippolito AM, Vockley CM, Hong LK, Leichter SM, Bartelt LC, Majoros WH, Song L, Safi A, Koçak DD, Gersbach CA, Hartemink AJ, Crawford GE, Engelhardt BE, Reddy TE.

Genome Res. 2018 Sep;28(9):1272-1284. doi: 10.1101/gr.233346.117. Epub 2018 Aug 10.

4.

Estimation of the prevalence of cholesteryl ester storage disorder in a cohort of patients with clinical features of familial hypercholesterolaemia.

Ashfield-Watt P, Haralambos K, Edwards R, Townsend D, Gingell R, Wa Li K, Humphries SE, McDowell I.

Ann Clin Biochem. 2019 Jan;56(1):112-117. doi: 10.1177/0004563218793165. Epub 2018 Aug 8.

PMID:
30056760
5.

Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids.

D'Ippolito AM, McDowell IC, Barrera A, Hong LK, Leichter SM, Bartelt LC, Vockley CM, Majoros WH, Safi A, Song L, Gersbach CA, Crawford GE, Reddy TE.

Cell Syst. 2018 Aug 22;7(2):146-160.e7. doi: 10.1016/j.cels.2018.06.007. Epub 2018 Jul 18.

PMID:
30031775
6.

Testing for Turkeys Faith-Based Community HIV Testing Initiative: An Update.

DeGrezia M, Baker D, McDowell I.

J Assoc Nurses AIDS Care. 2018 Sep - Oct;29(5):782-784. doi: 10.1016/j.jana.2018.05.007. Epub 2018 Jun 4.

PMID:
29907519
7.

Obesity in Pregnancy: Risks and Management.

Riley L, Wertz M, McDowell I.

Am Fam Physician. 2018 May 1;97(9):559-561. No abstract available.

8.

Coronary heart disease mortality in treated familial hypercholesterolaemia: Update of the UK Simon Broome FH register.

Humphries SE, Cooper JA, Seed M, Capps N, Durrington PN, Jones B, McDowell IFW, Soran H, Neil HAW; Simon Broome Familial Hyperlipidaemia Register Group.

Atherosclerosis. 2018 Jul;274:41-46. doi: 10.1016/j.atherosclerosis.2018.04.040. Epub 2018 May 1.

9.

Clustering gene expression time series data using an infinite Gaussian process mixture model.

McDowell IC, Manandhar D, Vockley CM, Schmid AK, Reddy TE, Engelhardt BE.

PLoS Comput Biol. 2018 Jan 16;14(1):e1005896. doi: 10.1371/journal.pcbi.1005896. eCollection 2018 Jan.

10.

Co-expression networks reveal the tissue-specific regulation of transcription and splicing.

Saha A, Kim Y, Gewirtz ADH, Jo B, Gao C, McDowell IC; GTEx Consortium, Engelhardt BE, Battle A.

Genome Res. 2017 Nov;27(11):1843-1858. doi: 10.1101/gr.216721.116. Epub 2017 Oct 11.

11.

A long-range flexible billboard model of gene activation.

Vockley CM, McDowell IC, D'Ippolito AM, Reddy TE.

Transcription. 2017 Aug 8;8(4):261-267. doi: 10.1080/21541264.2017.1317694. Epub 2017 Jun 9.

12.

Transversions have larger regulatory effects than transitions.

Guo C, McDowell IC, Nodzenski M, Scholtens DM, Allen AS, Lowe WL, Reddy TE.

BMC Genomics. 2017 May 19;18(1):394. doi: 10.1186/s12864-017-3785-4.

13.

Genetic determinants of adiponectin regulation revealed by pregnancy.

Hivert MF, Scholtens DM, Allard C, Nodzenski M, Bouchard L, Brisson D, Lowe LP, McDowell I, Reddy T, Dastani Z, Richards JB, Hayes MG, Lowe WL Jr.

Obesity (Silver Spring). 2017 May;25(5):935-944. doi: 10.1002/oby.21805. Epub 2017 Mar 20.

14.

Requesting a unique personal identifier or providing a souvenir incentive did not affect overall consent to health record linkage: evidence from an RCT nested within a cohort.

Ni MY, Li TK, Hui RWH, McDowell I, Leung GM.

J Clin Epidemiol. 2017 Apr;84:142-149. doi: 10.1016/j.jclinepi.2017.01.003. Epub 2017 Jan 20.

PMID:
28115256
15.

What it means to be a midwife.

McDowell I.

Nurs Stand. 2016 Dec 7;31(15):36.

PMID:
27925535
16.

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome.

Vockley CM, D'Ippolito AM, McDowell IC, Majoros WH, Safi A, Song L, Crawford GE, Reddy TE.

Cell. 2016 Aug 25;166(5):1269-1281.e19. doi: 10.1016/j.cell.2016.07.049.

17.

Context Specific and Differential Gene Co-expression Networks via Bayesian Biclustering.

Gao C, McDowell IC, Zhao S, Brown CD, Engelhardt BE.

PLoS Comput Biol. 2016 Jul 28;12(7):e1004791. doi: 10.1371/journal.pcbi.1004791. eCollection 2016 Jul.

18.

Diagnostic scoring for familial hypercholesterolaemia in practice.

Haralambos K, Ashfield-Watt P, McDowell IF.

Curr Opin Lipidol. 2016 Aug;27(4):367-74. doi: 10.1097/MOL.0000000000000325. Review.

PMID:
27389632
19.

Multi-species protein similarity clustering reveals novel expanded immune gene families in the eastern oyster Crassostrea virginica.

McDowell IC, Modak TH, Lane CE, Gomez-Chiarri M.

Fish Shellfish Immunol. 2016 Jun;53:13-23. doi: 10.1016/j.fsi.2016.03.157. Epub 2016 Mar 28. Review.

PMID:
27033806
20.

Zinc in denture adhesive: a rare cause of copper deficiency in a patient on home parenteral nutrition.

Prasad R, Hawthorne B, Durai D, McDowell I.

BMJ Case Rep. 2015 Oct 9;2015. pii: bcr2015211390. doi: 10.1136/bcr-2015-211390.

21.

Structure and validity of Family Harmony Scale: An instrument for measuring harmony.

Kavikondala S, Stewart SM, Ni MY, Chan BH, Lee PH, Li KK, McDowell I, Johnston JM, Chan SS, Lam TH, Lam WW, Fielding R, Leung GM.

Psychol Assess. 2016 Mar;28(3):307-18. doi: 10.1037/pas0000131. Epub 2015 Jul 6.

PMID:
26146946
22.

Clinical experience of scoring criteria for Familial Hypercholesterolaemia (FH) genetic testing in Wales.

Haralambos K, Whatley SD, Edwards R, Gingell R, Townsend D, Ashfield-Watt P, Lansberg P, Datta DB, McDowell IF.

Atherosclerosis. 2015 May;240(1):190-6. doi: 10.1016/j.atherosclerosis.2015.03.003. Epub 2015 Mar 6.

PMID:
25797312
23.

Cohort Profile: FAMILY Cohort.

Leung GM, Ni MY, Wong PT, Lee PH, Chan BH, Stewart SM, Schooling CM, Johnston JM, Lam WW, Chan SS, McDowell I, Lam TH, Pang H, Fielding R.

Int J Epidemiol. 2017 Apr 1;46(2):e1. doi: 10.1093/ije/dyu257.

PMID:
25617647
24.
25.

Transcriptome of American oysters, Crassostrea virginica, in response to bacterial challenge: insights into potential mechanisms of disease resistance.

McDowell IC, Nikapitiya C, Aguiar D, Lane CE, Istrail S, Gomez-Chiarri M.

PLoS One. 2014 Aug 14;9(8):e105097. doi: 10.1371/journal.pone.0105097. eCollection 2014.

26.

Identification of potential general markers of disease resistance in American oysters, Crassostrea virginica through gene expression studies.

Nikapitiya C, McDowell IC, Villamil L, Muñoz P, Sohn S, Gomez-Chiarri M.

Fish Shellfish Immunol. 2014 Nov;41(1):27-36. doi: 10.1016/j.fsi.2014.06.015. Epub 2014 Jun 26.

PMID:
24973516
27.

Psychometric evaluation of the Chinese version of the Subjective Happiness Scale: evidence from the Hong Kong FAMILY Cohort.

Nan H, Ni MY, Lee PH, Tam WW, Lam TH, Leung GM, McDowell I.

Int J Behav Med. 2014 Aug;21(4):646-52. doi: 10.1007/s12529-014-9389-3.

28.

Patient experience. Telling tales could cut complaints.

McDowell I.

Health Serv J. 2013 Jan 10;123(6334):30-1. No abstract available.

PMID:
23437749
29.

For non-exercising people, the number of steps walked is more strongly associated with health than time spent walking.

Lee PH, Nan H, Yu YY, McDowell I, Leung GM, Lam TH.

J Sci Med Sport. 2013 May;16(3):227-30. doi: 10.1016/j.jsams.2012.10.005. Epub 2012 Nov 13.

PMID:
23154156
30.

Depressive symptoms in people with chronic physical conditions: prevalence and risk factors in a Hong Kong community sample.

Nan H, Lee PH, McDowell I, Ni MY, Stewart SM, Lam TH.

BMC Psychiatry. 2012 Nov 14;12:198. doi: 10.1186/1471-244X-12-198.

31.

Differential prediction of vascular dementia and Alzheimer's disease in nondemented older adults within 5 years of initial testing.

Brewster PW, McDowell I, Moineddin R, Tierney MC.

Alzheimers Dement. 2012 Nov;8(6):528-35. doi: 10.1016/j.jalz.2011.09.233.

PMID:
23102122
32.

Perspectives on family health, happiness and harmony (3H) among Hong Kong Chinese people: a qualitative study.

Lam WW, Fielding R, McDowell I, Johnston J, Chan S, Leung GM, Lam TH.

Health Educ Res. 2012 Oct;27(5):767-79. doi: 10.1093/her/cys087. Epub 2012 Aug 20.

PMID:
22907531
33.

A cluster analysis of patterns of objectively measured physical activity in Hong Kong.

Lee PH, Yu YY, McDowell I, Leung GM, Lam TH.

Public Health Nutr. 2013 Aug;16(8):1436-44. doi: 10.1017/S1368980012003631. Epub 2012 Aug 16.

PMID:
22894896
34.

A primer on population health: a new resource for students and clinicians.

Shore B, McDowell I, Johnson IL, Donovan D.

Am J Prev Med. 2011 Oct;41(4 Suppl 3):S302-3. doi: 10.1016/j.amepre.2011.05.023.

PMID:
21961680
35.

Performance of the international physical activity questionnaire (short form) in subgroups of the Hong Kong chinese population.

Lee PH, Yu YY, McDowell I, Leung GM, Lam TH, Stewart SM.

Int J Behav Nutr Phys Act. 2011 Aug 1;8:81. doi: 10.1186/1479-5868-8-81.

36.

Culturally Safe Epidemiology: Oxymoron or Scientific Imperative.

Cameron M, Andersson N, McDowell I, Ledogar RJ.

Pimatisiwin. 2010 Fall;8(2):89-116.

37.

Prediction of all-cause dementia using neuropsychological tests within 10 and 5 years of diagnosis in a community-based sample.

Tierney MC, Moineddin R, McDowell I.

J Alzheimers Dis. 2010;22(4):1231-40. doi: 10.3233/JAD-2010-100516.

PMID:
20930315
38.

Measures of self-perceived well-being.

McDowell I.

J Psychosom Res. 2010 Jul;69(1):69-79. doi: 10.1016/j.jpsychores.2009.07.002. Epub 2009 Sep 30. Review.

PMID:
20630265
39.

Integrating provision of specialist lipid services with cascade testing for familial hypercholesterolaemia.

Datta BN, McDowell IF, Rees A.

Curr Opin Lipidol. 2010 Aug;21(4):366-71. doi: 10.1097/MOL.0b013e32833c14e2. Review.

PMID:
20613514
40.

All-cause and cardiovascular mortality in treated patients with severe hypertriglyceridaemia: A long-term prospective registry study.

Neil HA, Cooper J, Betteridge DJ, Capps N, McDowell IF, Durrington PN, Seed M, Mann JI, Humphries SE; Simon Broome Familial Hyperlipidaemia Register Group.

Atherosclerosis. 2010 Aug;211(2):618-23. doi: 10.1016/j.atherosclerosis.2010.03.006. Epub 2010 Mar 9.

PMID:
20356595
41.

Conceptualizing the healthscape: contributions of time geography, location technologies and spatial ecology to place and health research.

Rainham D, McDowell I, Krewski D, Sawada M.

Soc Sci Med. 2010 Mar;70(5):668-76. doi: 10.1016/j.socscimed.2009.10.035. Epub 2009 Dec 4.

PMID:
19963310
42.

A survey of Cambodian health-care providers' HIV knowledge, attitudes and intentions to take a sexual history.

Webber G, Edwards N, Graham ID, Amaratunga C, Gaboury I, Keane V, Ros S, McDowell I.

Int J STD AIDS. 2009 May;20(5):346-50. doi: 10.1258/ijsa.2008.008390.

PMID:
19386973
43.

Development of a wearable global positioning system for place and health research.

Rainham D, Krewski D, McDowell I, Sawada M, Liekens B.

Int J Health Geogr. 2008 Nov 25;7:59. doi: 10.1186/1476-072X-7-59.

44.

The feasibility of establishing correction factors to adjust self-reported estimates of obesity.

Connor Gorber S, Shields M, Tremblay MS, McDowell I.

Health Rep. 2008 Sep;19(3):71-82.

45.

Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercholesterolaemia: a prospective registry study.

Neil A, Cooper J, Betteridge J, Capps N, McDowell I, Durrington P, Seed M, Humphries SE.

Eur Heart J. 2008 Nov;29(21):2625-33. doi: 10.1093/eurheartj/ehn422. Epub 2008 Oct 7.

46.

From risk factors to explanation in public health.

McDowell I.

J Public Health (Oxf). 2008 Sep;30(3):219-23. doi: 10.1093/pubmed/fdn051. Epub 2008 Jul 11. No abstract available. Erratum in: J Public Health (Oxf). 2008 Dec;30(4):517.

PMID:
18621784
47.

The contribution of ApoB and ApoA1 measurements to cardiovascular risk assessment.

Andrikoula M, McDowell IF.

Diabetes Obes Metab. 2008 Apr;10(4):271-8. doi: 10.1111/j.1463-1326.2007.00714.x. Review.

PMID:
18333887
48.

Lipid-lowering agents and the risk of cognitive impairment that does not meet criteria for dementia, in relation to apolipoprotein E status.

Rockwood K, Howlett S, Fisk J, Darvesh S, Tuokko H, Hogan DB, Wolfson C, McDowell I.

Neuroepidemiology. 2007;29(3-4):201-7. Epub 2007 Nov 27.

PMID:
18043005
49.

Living long and keeping well: elderly Canadians account for success in aging.

Bassett R, Bourbonnais V, McDowell I.

Can J Aging. 2007 Summer;26(2):113-26.

PMID:
17613443
50.

Mapping the connections between education and dementia.

McDowell I, Xi G, Lindsay J, Tierney M.

J Clin Exp Neuropsychol. 2007 Feb;29(2):127-41.

PMID:
17365248

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