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Items: 43

1.

Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era.

van der Heul HU, Bilyk BL, McDowall KJ, Seipke RF, van Wezel GP.

Nat Prod Rep. 2018 Jun 20;35(6):575-604. doi: 10.1039/c8np00012c. Review.

2.

An Improved Binary Vector and Escherichia coli Strain for Agrobacterium tumefaciens-Mediated Plant Transformation.

Watson MR, Lin YF, Hollwey E, Dodds RE, Meyer P, McDowall KJ.

G3 (Bethesda). 2016 Jul 7;6(7):2195-201. doi: 10.1534/g3.116.029405.

3.

Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family.

Kime L, Vincent HA, Gendoo DM, Jourdan SS, Fishwick CW, Callaghan AJ, McDowall KJ.

Sci Rep. 2015 Jul 13;5:9781. doi: 10.1038/srep09781. No abstract available.

4.

Transcriptional analysis of the cell division-related ssg genes in Streptomyces coelicolor reveals direct control of ssgR by AtrA.

Kim SH, Traag BA, Hasan AH, McDowall KJ, Kim BG, van Wezel GP.

Antonie Van Leeuwenhoek. 2015 Jul;108(1):201-13. doi: 10.1007/s10482-015-0479-2. Epub 2015 May 23.

5.

Binding of a biosynthetic intermediate to AtrA modulates the production of lidamycin by Streptomyces globisporus.

Li X, Yu T, He Q, McDowall KJ, Jiang B, Jiang Z, Wu L, Li G, Li Q, Wang S, Shi Y, Wang L, Hong B.

Mol Microbiol. 2015 Jun;96(6):1257-71. doi: 10.1111/mmi.13004. Epub 2015 Apr 24.

6.

The first small-molecule inhibitors of members of the ribonuclease E family.

Kime L, Vincent HA, Gendoo DM, Jourdan SS, Fishwick CW, Callaghan AJ, McDowall KJ.

Sci Rep. 2015 Jan 26;5:8028. doi: 10.1038/srep08028. Erratum in: Sci Rep. 2015;5:9781.

7.

A comparison of key aspects of gene regulation in Streptomyces coelicolor and Escherichia coli using nucleotide-resolution transcription maps produced in parallel by global and differential RNA sequencing.

Romero DA, Hasan AH, Lin YF, Kime L, Ruiz-Larrabeiti O, Urem M, Bucca G, Mamanova L, Laing EE, van Wezel GP, Smith CP, Kaberdin VR, McDowall KJ.

Mol Microbiol. 2014 Sep 30. doi: 10.1111/mmi.12810. [Epub ahead of print]

8.

Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli.

Clarke JE, Kime L, Romero A D, McDowall KJ.

Nucleic Acids Res. 2014 Oct;42(18):11733-51. doi: 10.1093/nar/gku808. Epub 2014 Sep 18.

9.

Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry.

Kime L, Clarke JE, Romero A D, Grasby JA, McDowall KJ.

Nucleic Acids Res. 2014 Apr;42(7):4577-89. doi: 10.1093/nar/gkt1403. Epub 2014 Jan 21.

11.

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances.

van Wezel GP, McDowall KJ.

Nat Prod Rep. 2011 Jul;28(7):1311-33. doi: 10.1039/c1np00003a. Epub 2011 May 25. Review.

PMID:
21611665
12.

Dietary zinc oxide affects the expression of genes associated with inflammation: Transcriptome analysis in piglets challenged with ETEC K88.

Sargeant HR, McDowall KJ, Miller HM, Shaw MA.

Vet Immunol Immunopathol. 2010 Sep 15;137(1-2):120-9. doi: 10.1016/j.vetimm.2010.05.001. Epub 2010 May 13.

PMID:
20605641
13.

The permease gene nagE2 is the key to N-acetylglucosamine sensing and utilization in Streptomyces coelicolor and is subject to multi-level control.

Nothaft H, Rigali S, Boomsma B, Swiatek M, McDowall KJ, van Wezel GP, Titgemeyer F.

Mol Microbiol. 2010 Mar;75(5):1133-44. doi: 10.1111/j.1365-2958.2009.07020.x.

14.

The sequence of sites recognised by a member of the RNase E/G family can control the maximal rate of cleavage, while a 5'-monophosphorylated end appears to function cooperatively in mediating RNA binding.

Jourdan SS, Kime L, McDowall KJ.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):879-83. doi: 10.1016/j.bbrc.2009.11.156. Epub 2009 Nov 27.

PMID:
19945430
15.

Rapid cleavage of RNA by RNase E in the absence of 5' monophosphate stimulation.

Kime L, Jourdan SS, Stead JA, Hidalgo-Sastre A, McDowall KJ.

Mol Microbiol. 2010 May;76(3):590-604. doi: 10.1111/j.1365-2958.2009.06935.x. Epub 2009 Nov 2.

16.

Endonucleolytic initiation of mRNA decay in Escherichia coli.

Carpousis AJ, Luisi BF, McDowall KJ.

Prog Mol Biol Transl Sci. 2009;85:91-135. doi: 10.1016/S0079-6603(08)00803-9. Review.

PMID:
19215771
17.

Identifying and characterizing substrates of the RNase E/G family of enzymes.

Kime L, Jourdan SS, McDowall KJ.

Methods Enzymol. 2008;447:215-41. doi: 10.1016/S0076-6879(08)02212-X.

PMID:
19161846
18.

Translational activation by the noncoding RNA DsrA involves alternative RNase III processing in the rpoS 5'-leader.

Resch A, Afonyushkin T, Lombo TB, McDowall KJ, Bläsi U, Kaberdin VR.

RNA. 2008 Mar;14(3):454-9. doi: 10.1261/rna.603108. Epub 2008 Jan 11.

20.

Two-dimensional gel electrophoresis for identifying proteins that bind DNA or RNA.

Stead JA, McDowall KJ.

Nat Protoc. 2007;2(8):1839-48.

PMID:
17703194
21.

Streptomycin production by Streptomyces griseus can be modulated by a mechanism not associated with change in the adpA component of the A-factor cascade.

Hong B, Phornphisutthimas S, Tilley E, Baumberg S, McDowall KJ.

Biotechnol Lett. 2007 Jan;29(1):57-64. Epub 2006 Nov 22.

PMID:
17120093
22.
23.
24.

Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover.

Callaghan AJ, Marcaida MJ, Stead JA, McDowall KJ, Scott WG, Luisi BF.

Nature. 2005 Oct 20;437(7062):1187-91.

25.

Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor.

Uguru GC, Stephens KE, Stead JA, Towle JE, Baumberg S, McDowall KJ.

Mol Microbiol. 2005 Oct;58(1):131-50.

26.

Differential expression and extent of fungal/plant and fungal/bacterial chitinases of Aspergillus fumigatus.

Taib M, Pinney JW, Westhead DR, McDowall KJ, Adams DJ.

Arch Microbiol. 2005 Oct;184(1):78-81. Epub 2005 Nov 3.

PMID:
16096835
27.

"Zn-link": a metal-sharing interface that organizes the quaternary structure and catalytic site of the endoribonuclease, RNase E.

Callaghan AJ, Redko Y, Murphy LM, Grossmann JG, Yates D, Garman E, Ilag LL, Robinson CV, Symmons MF, McDowall KJ, Luisi BF.

Biochemistry. 2005 Mar 29;44(12):4667-75.

PMID:
15779893
28.

Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain.

Callaghan AJ, Grossmann JG, Redko YU, Ilag LL, Moncrieffe MC, Symmons MF, Robinson CV, McDowall KJ, Luisi BF.

Biochemistry. 2003 Dec 2;42(47):13848-55.

PMID:
14636052
29.

Determination of the catalytic parameters of the N-terminal half of Escherichia coli ribonuclease E and the identification of critical functional groups in RNA substrates.

Redko Y, Tock MR, Adams CJ, Kaberdin VR, Grasby JA, McDowall KJ.

J Biol Chem. 2003 Nov 7;278(45):44001-8. Epub 2003 Aug 27.

30.

A stereodivergent, two-directional synthesis of stereoisomeric C-linked disaccharide mimetics.

Harding M, Hodgson R, Majid T, McDowall KJ, Nelson A.

Org Biomol Chem. 2003 Jan 21;1(2):338-49.

PMID:
12929429
31.
32.

Cleavage of poly(A) tails on the 3'-end of RNA by ribonuclease E of Escherichia coli.

Walsh AP, Tock MR, Mallen MH, Kaberdin VR, von Gabain A, McDowall KJ.

Nucleic Acids Res. 2001 May 1;29(9):1864-71.

33.

Enhanced cleavage of RNA mediated by an interaction between substrates and the arginine-rich domain of E. coli ribonuclease E.

Kaberdin VR, Walsh AP, Jakobsen T, McDowall KJ, von Gabain A.

J Mol Biol. 2000 Aug 11;301(2):257-64.

PMID:
10926508
34.
36.
37.

RNase E: still a wonderfully mysterious enzyme.

Cohen SN, McDowall KJ.

Mol Microbiol. 1997 Mar;23(6):1099-106. Review.

39.

Site-specific RNase E cleavage of oligonucleotides and inhibition by stem-loops.

McDowall KJ, Kaberdin VR, Wu SW, Cohen SN, Lin-Chao S.

Nature. 1995 Mar 16;374(6519):287-90.

PMID:
7533896
40.
41.

A+U content rather than a particular nucleotide order determines the specificity of RNase E cleavage.

McDowall KJ, Lin-Chao S, Cohen SN.

J Biol Chem. 1994 Apr 8;269(14):10790-6.

43.

Characterization of an oxytetracycline-resistance gene, otrA, of Streptomyces rimosus.

Doyle D, McDowall KJ, Butler MJ, Hunter IS.

Mol Microbiol. 1991 Dec;5(12):2923-33.

PMID:
1809836

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