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Seasonal temperatures and hydrological conditions improve the prediction of West Nile virus infection rates in Culex mosquitoes and human case counts in New York and Connecticut.

Keyel AC, Elison Timm O, Backenson PB, Prussing C, Quinones S, McDonough KA, Vuille M, Conn JE, Armstrong PM, Andreadis TG, Kramer LD.

PLoS One. 2019 Jun 3;14(6):e0217854. doi: 10.1371/journal.pone.0217854. eCollection 2019.


Insights Into the Evolution of Staphylococcus aureus Daptomycin Resistance From an in vitro Bioreactor Model.

Lasek-Nesselquist E, Lu J, Schneider R, Ma Z, Russo V, Mishra S, Pai MP, Pata JD, McDonough KA, Malik M.

Front Microbiol. 2019 Feb 28;10:345. doi: 10.3389/fmicb.2019.00345. eCollection 2019.


Discovery of Small-Molecule Antibiotics against a Unique tRNA-Mediated Regulation of Transcription in Gram-Positive Bacteria.

Frohlich KM, Weintraub SF, Bell JT, Todd GC, Väre VYP, Schneider R, Kloos ZA, Tabe ES, Cantara WA, Stark CJ, Onwuanaibe UJ, Duffy BC, Basanta-Sanchez M, Kitchen DB, McDonough KA, Agris PF.

ChemMedChem. 2019 Apr 3;14(7):758-769. doi: 10.1002/cmdc.201800744. Epub 2019 Mar 1.


AbmR (Rv1265) is a novel transcription factor of Mycobacterium tuberculosis that regulates host cell association and expression of the non-coding small RNA Mcr11.

Girardin RC, Bai G, He J, Sui H, McDonough KA.

Mol Microbiol. 2018 Dec;110(5):811-830. doi: 10.1111/mmi.14126. Epub 2018 Oct 21.


Cyclic nucleotide signaling in Mycobacterium tuberculosis: an expanding repertoire.

Johnson RM, McDonough KA.

Pathog Dis. 2018 Jul 1;76(5). doi: 10.1093/femspd/fty048.


Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.

Ranganathan S, Cheung J, Cassidy M, Ginter C, Pata JD, McDonough KA.

Nucleic Acids Res. 2018 Jan 9;46(1):403-420. doi: 10.1093/nar/gkx1148.


Interprofessional Error Disclosure Training for Medical, Nursing, Pharmacy, Dental, and Physician Assistant Students.

McDonough KA, White AA, Odegard PS, Shannon SE.

MedEdPORTAL. 2017 Jul 21;13:10606. doi: 10.15766/mep_2374-8265.10606.


Chemical activation of adenylyl cyclase Rv1625c inhibits growth of Mycobacterium tuberculosis on cholesterol and modulates intramacrophage signaling.

Johnson RM, Bai G, DeMott CM, Banavali NK, Montague CR, Moon C, Shekhtman A, VanderVen B, McDonough KA.

Mol Microbiol. 2017 Jul;105(2):294-308. doi: 10.1111/mmi.13701. Epub 2017 May 23.


Combined Bioinformatic and Rational Design Approach To Develop Antimicrobial Peptides against Mycobacterium tuberculosis.

Pearson CS, Kloos Z, Murray B, Tabe E, Gupta M, Kwak JH, Karande P, McDonough KA, Belfort G.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):2757-64. doi: 10.1128/AAC.00940-15. Print 2016 May.


Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon.

Ranganathan S, Bai G, Lyubetskaya A, Knapp GS, Peterson MW, Gazdik M, C Gomes AL, Galagan JE, McDonough KA.

Nucleic Acids Res. 2016 Jan 8;44(1):134-51. doi: 10.1093/nar/gkv889. Epub 2015 Sep 10.


Role of intragenic binding of cAMP responsive protein (CRP) in regulation of the succinate dehydrogenase genes Rv0249c-Rv0247c in TB complex mycobacteria.

Knapp GS, Lyubetskaya A, Peterson MW, Gomes AL, Ma Z, Galagan JE, McDonough KA.

Nucleic Acids Res. 2015 Jun 23;43(11):5377-93. doi: 10.1093/nar/gkv420. Epub 2015 May 4.


Caught in action: selecting peptide aptamers against intrinsically disordered proteins in live cells.

Cobbert JD, DeMott C, Majumder S, Smith EA, Reverdatto S, Burz DS, McDonough KA, Shekhtman A.

Sci Rep. 2015 Mar 24;5:9402. doi: 10.1038/srep09402.


Cyclic AMP Signaling in Mycobacteria.

Knapp GS, McDonough KA.

Microbiol Spectr. 2014 Apr;2(2). doi: 10.1128/microbiolspec.MGM2-0011-2013. Review.


Identification of novel sRNAs in mycobacterial species.

Tsai CH, Baranowski C, Livny J, McDonough KA, Wade JT, Contreras LM.

PLoS One. 2013 Nov 14;8(11):e79411. doi: 10.1371/journal.pone.0079411. eCollection 2013.


Identification and characterization of small RNAs in Yersinia pestis.

Beauregard A, Smith EA, Petrone BL, Singh N, Karch C, McDonough KA, Wade JT.

RNA Biol. 2013 Mar;10(3):397-405. doi: 10.4161/rna.23590. Epub 2013 Jan 16.


Definition and annotation of (myco)bacterial non-coding RNA.

Lamichhane G, Arnvig KB, McDonough KA.

Tuberculosis (Edinb). 2013 Jan;93(1):26-9. doi: 10.1016/ Epub 2013 Jan 4.


The myriad roles of cyclic AMP in microbial pathogens: from signal to sword.

McDonough KA, Rodriguez A.

Nat Rev Microbiol. 2011 Nov 14;10(1):27-38. doi: 10.1038/nrmicro2688. Review.


Dysregulation of serine biosynthesis contributes to the growth defect of a Mycobacterium tuberculosis crp mutant.

Bai G, Schaak DD, Smith EA, McDonough KA.

Mol Microbiol. 2011 Oct;82(1):180-98. doi: 10.1111/j.1365-2958.2011.07806.x. Epub 2011 Sep 8.


Cyclic AMP signalling in mycobacteria: redirecting the conversation with a common currency.

Bai G, Knapp GS, McDonough KA.

Cell Microbiol. 2011 Mar;13(3):349-58. doi: 10.1111/j.1462-5822.2010.01562.x. Epub 2010 Dec 28. Review.


The importance of the small RNA chaperone Hfq for growth of epidemic Yersinia pestis, but not Yersinia pseudotuberculosis, with implications for plague biology.

Bai G, Golubov A, Smith EA, McDonough KA.

J Bacteriol. 2010 Aug;192(16):4239-45. doi: 10.1128/JB.00504-10. Epub 2010 Jun 11.


Multiple small RNAs identified in Mycobacterium bovis BCG are also expressed in Mycobacterium tuberculosis and Mycobacterium smegmatis.

DiChiara JM, Contreras-Martinez LM, Livny J, Smith D, McDonough KA, Belfort M.

Nucleic Acids Res. 2010 Jul;38(12):4067-78. doi: 10.1093/nar/gkq101. Epub 2010 Feb 24.


cAMP levels within Mycobacterium tuberculosis and Mycobacterium bovis BCG increase upon infection of macrophages.

Bai G, Schaak DD, McDonough KA.

FEMS Immunol Med Microbiol. 2009 Jan;55(1):68-73. doi: 10.1111/j.1574-695X.2008.00500.x. Epub 2008 Dec 6.


Rv1675c (cmr) regulates intramacrophage and cyclic AMP-induced gene expression in Mycobacterium tuberculosis-complex mycobacteria.

Gazdik MA, Bai G, Wu Y, McDonough KA.

Mol Microbiol. 2009 Jan;71(2):434-48. doi: 10.1111/j.1365-2958.2008.06541.x. Epub 2008 Nov 14.


Expression of the Mycobacterium tuberculosis acr-coregulated genes from the DevR (DosR) regulon is controlled by multiple levels of regulation.

Vasudeva-Rao HM, McDonough KA.

Infect Immun. 2008 Jun;76(6):2478-89. doi: 10.1128/IAI.01443-07. Epub 2008 Apr 7.


Severe drug hypersensitivity reaction in a young woman treated with doxycycline.

Robles DT, Leonard JL, Compton N, Waghmare A, McDonough KA, George E, Wolgamot G, Fleckman P.

Dermatology. 2008;217(1):23-6. doi: 10.1159/000119753. Epub 2008 Mar 10.


A Mycobacterium marinum zone of inhibition assay as a method for screening potential antimycobacterial compounds from marine extracts.

Barker LP, Lien BA, Brun OS, Schaak DD, McDonough KA, Chang LC.

Planta Med. 2007 Jun;73(6):559-63. Epub 2007 May 30.


Evidence that accumulation of mutants in a biofilm reflects natural selection rather than stress-induced adaptive mutation.

Banas JA, Miller JD, Fuschino ME, Hazlett KR, Toyofuku W, Porter KA, Reutzel SB, Florczyk MA, McDonough KA, Michalek SM.

Appl Environ Microbiol. 2007 Jan;73(1):357-61. Epub 2006 Nov 3.


Development and evaluation of a 4-target multiplex real-time polymerase chain reaction assay for the detection and characterization of Yersinia pestis.

Woron AM, Nazarian EJ, Egan C, McDonough KA, Cirino NM, Limberger RJ, Musser KA.

Diagn Microbiol Infect Dis. 2006 Nov;56(3):261-8. Epub 2006 Sep 1.


Inpatient management of diabetes.

McDonough KA, DeWitt DE.

Prim Care. 2003 Sep;30(3):557-67. Review.


A family of acr-coregulated Mycobacterium tuberculosis genes shares a common DNA motif and requires Rv3133c (dosR or devR) for expression.

Florczyk MA, McCue LA, Purkayastha A, Currenti E, Wolin MJ, McDonough KA.

Infect Immun. 2003 Sep;71(9):5332-43.


Genome sequence of Yersinia pestis KIM.

Deng W, Burland V, Plunkett G 3rd, Boutin A, Mayhew GF, Liss P, Perna NT, Rose DJ, Mau B, Zhou S, Schwartz DC, Fetherston JD, Lindler LE, Brubaker RR, Plano GV, Straley SC, McDonough KA, Nilles ML, Matson JS, Blattner FR, Perry RD.

J Bacteriol. 2002 Aug;184(16):4601-11.


SSP2, a sporulation-specific gene necessary for outer spore wall assembly in the yeast Saccharomyces cerevisiae.

Sarkar PK, Florczyk MA, McDonough KA, Nag DK.

Mol Genet Genomics. 2002 May;267(3):348-58. Epub 2002 Apr 5.


Fluorescence-based detection of lacZ reporter gene expression in intact and viable bacteria including Mycobacterium species.

Rowland B, Purkayastha A, Monserrat C, Casart Y, Takiff H, McDonough KA.

FEMS Microbiol Lett. 1999 Oct 15;179(2):317-25.


The interaction of Mycobacterium tuberculosis with macrophages: a study of phagolysosome fusion.

McDonough KA, Kress Y, Bloom BR.

Infect Agents Dis. 1993 Aug;2(4):232-5. No abstract available.


Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages.

McDonough KA, Kress Y, Bloom BR.

Infect Immun. 1993 Jul;61(7):2763-73. Erratum in: Infect Immun 1993 Sep;61(9):4021-4.


Mutation in the pla gene of Yersinia pestis alters the course of the plague bacillus-flea (Siphonaptera: Ceratophyllidae) interaction.

McDonough KA, Barnes AM, Quan TJ, Montenieri J, Falkow S.

J Med Entomol. 1993 Jul;30(4):772-80.


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