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'When you hear hooves, think zebras, not horses'; two challenging cases of interstitial lung disease (ILD).

O'Callaghan M, Fabre A, Keane M, McDonnell TJ.

BMJ Case Rep. 2019 Feb 11;12(2). pii: bcr-2018-224507. doi: 10.1136/bcr-2018-224507.


Cytogenetics-based risk prediction of blastic transformation of chronic myeloid leukemia in the era of TKI therapy.

Gong Z, Medeiros LJ, Cortes JE, Chen Z, Zheng L, Li Y, Bai S, Lin P, Miranda RN, Jorgensen JL, McDonnell TJ, Wang W, Kantarjian HM, Hu S.

Blood Adv. 2017 Dec 8;1(26):2541-2552. doi: 10.1182/bloodadvances.2017011858. eCollection 2017 Dec 12.


Comparison of outpatient and home-based exercise training programmes for COPD: A systematic review and meta-analysis.

Wuytack F, Devane D, Stovold E, McDonnell M, Casey M, McDonnell TJ, Gillespie P, Raymakers A, Lacasse Y, McCarthy B.

Respirology. 2018 Mar;23(3):272-283. doi: 10.1111/resp.13224. Epub 2017 Nov 30. Review.


Case of coccidioidomycosis in Ireland.

Duggan PT, Deegan AP, McDonnell TJ.

BMJ Case Rep. 2016 Aug 11;2016. pii: bcr2016215898. doi: 10.1136/bcr-2016-215898.


Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell lymphoma patients treated with rituximab-CHOP.

Xu-Monette ZY, Dabaja BS, Wang X, Tu M, Manyam GC, Tzankov A, Xia Y, Zhang L, Sun R, Visco C, Dybkaer K, Yin L, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Ferreri AJ, Møller MB, Parsons BM, Zhao X, Winter JN, Piris MA, McDonnell TJ, Miranda RN, Li Y, Medeiros LJ, Young KH.

Mod Pathol. 2015 Dec;28(12):1555-73. doi: 10.1038/modpathol.2015.118. Epub 2015 Nov 6.


Clinical and prognostic significance of 3q26.2 and other chromosome 3 abnormalities in CML in the era of tyrosine kinase inhibitors.

Wang W, Cortes JE, Lin P, Beaty MW, Ai D, Amin HM, McDonnell TJ, Ok CY, Kantarjian HM, Medeiros LJ, Hu S.

Blood. 2015 Oct 1;126(14):1699-706. doi: 10.1182/blood-2015-05-646489. Epub 2015 Aug 4.


Defining exacerbations in chronic obstructive pulmonary disease.

Hawkins PE, Alam J, McDonnell TJ, Kelly E.

Expert Rev Respir Med. 2015 Jun;9(3):277-86. doi: 10.1586/17476348.2015.1046438. Review.


Pulmonary non-tuberculous mycobacteria in a general respiratory population.

Chong SG, Kent BD, Fitzgerald S, McDonnell TJ.

Ir Med J. 2014 Jul-Aug;107(7):207-9.


Recurrent pneumothoraces in a 65-year-old female: an unusual case of cystic lung disease.

Giin Chong S, Mitchell P, Fabre A, McDonnell TJ.

Eur Respir Rev. 2014 Jun;23(132):271-2. doi: 10.1183/09059180.00005013. No abstract available.


Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma.

Yoshimura M, Ishizawa J, Ruvolo V, Dilip A, Quintás-Cardama A, McDonnell TJ, Neelapu SS, Kwak LW, Shacham S, Kauffman M, Tabe Y, Yokoo M, Kimura S, Andreeff M, Kojima K.

Cancer Sci. 2014 Jul;105(7):795-801. doi: 10.1111/cas.12430. Epub 2014 Jun 3.


COPD exacerbations -- a comparison of Irish data with European data from the ERS COPD Audit.

Crinion S, Cotter O, Kennedy B, O'Connor B, Curran DR, McCormack S, McDonnell TJ, O'Connor TM.

Ir Med J. 2013 Oct;106(9):268, 270-2.


Combined pulmonary involvement in hereditary lysozyme amyloidosis with associated pulmonary sarcoidosis: a case report.

McCarthy C, Deegan AP, Garvey JF, McDonnell TJ.

Sarcoidosis Vasc Diffuse Lung Dis. 2013 Dec 17;30(4):321-4.


Use of a care bundle in the emergency department for acute exacerbations of chronic obstructive pulmonary disease: a feasibility study.

McCarthy C, Brennan JR, Brown L, Donaghy D, Jones P, Whelan R, McCormack N, Callanan I, Ryan J, McDonnell TJ.

Int J Chron Obstruct Pulmon Dis. 2013;8:605-11. doi: 10.2147/COPD.S52883. Epub 2013 Nov 28.


Late onset tuberculosis infection in patients receiving anti-TNFα therapy.

Mongey AB, Doran JP, Kleinerova J, Fitzgerald O, McDonnell TJ.

QJM. 2014 Jan;107(1):69-71. doi: 10.1093/qjmed/hct174. Epub 2013 Aug 22. No abstract available.


Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.

Chari NS, Romano RA, Koster MI, Jaks V, Roop D, Flores ER, Teglund S, Sinha S, Gruber W, Aberger F, Medeiros LJ, Toftgard R, McDonnell TJ.

Cell Death Differ. 2013 Aug;20(8):1080-8. doi: 10.1038/cdd.2013.41. Epub 2013 May 17.


Overwhelming support among urban Irish COPD patients for lung cancer screening by low-dose CT scan.

Pallin M, Walsh S, O'Driscoll MF, Murray C, Cahalane A, Brown L, Carter M, Mitchell P, McDonnell TJ, Butler MW.

Lung. 2012 Dec;190(6):621-8. doi: 10.1007/s00408-012-9421-9. Epub 2012 Oct 12.


Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies.

Xu-Monette ZY, Medeiros LJ, Li Y, Orlowski RZ, Andreeff M, Bueso-Ramos CE, Greiner TC, McDonnell TJ, Young KH.

Blood. 2012 Apr 19;119(16):3668-83. doi: 10.1182/blood-2011-11-366062. Epub 2012 Jan 24. Review.


The E1B19K oncoprotein complexes with Beclin 1 to regulate autophagy in adenovirus-infected cells.

Piya S, White EJ, Klein SR, Jiang H, McDonnell TJ, Gomez-Manzano C, Fueyo J.

PLoS One. 2011;6(12):e29467. doi: 10.1371/journal.pone.0029467. Epub 2011 Dec 29.


Therapy-related myeloid neoplasms following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.

Zhou Y, Tang G, Medeiros LJ, McDonnell TJ, Keating MJ, Wierda WG, Wang SA.

Mod Pathol. 2012 Feb;25(2):237-45. doi: 10.1038/modpathol.2011.158. Epub 2011 Nov 11.


ARDS: survival has improved but is life worth living?

Pallin M, McDonnell TJ.

Ir Med J. 2011 Jul-Aug;104(7):197-8. No abstract available.


PI3 Kinase inhibition on TRAIL-induced apoptosis correlates with androgen-sensitivity and p21 expression in prostate cancer cells.

Kadowaki Y, Chari NS, Teo AE, Hashi A, Spurgers KB, McDonnell TJ.

Apoptosis. 2011 Jun;16(6):627-35. doi: 10.1007/s10495-011-0591-3.


Chemotherapy-associated recurrent pneumothoraces in lymphangioleiomyomatosis.

Kelly E, Mhurchu EN, Sukor S, McDonnell TJ, Tryfonopoulos D, Keane MP.

Respir Care. 2010 Nov;55(11):1491-4.


Organising pneumonia associated with fumaric acid ester treatment for psoriasis.

Deegan AP, Kirby B, Rogers S, Crotty TB, McDonnell TJ.

Clin Respir J. 2010 Oct;4(4):248-51. doi: 10.1111/j.1752-699X.2009.00180.x.


Herbal medicine--sets the heart racing!

McGovern E, McDonnell TJ.

Ir Med J. 2010 Jul-Aug;103(7):219.


The RB-E2F1 pathway regulates autophagy.

Jiang H, Martin V, Gomez-Manzano C, Johnson DG, Alonso M, White E, Xu J, McDonnell TJ, Shinojima N, Fueyo J.

Cancer Res. 2010 Oct 15;70(20):7882-93. doi: 10.1158/0008-5472.CAN-10-1604. Epub 2010 Aug 31.


Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features.

Wang SA, Jabbar K, Lu G, Chen SS, Galili N, Vega F, Jones D, Raza A, Kantarjian H, Garcia-Manero G, McDonnell TJ, Medeiros LJ.

Leukemia. 2010 Apr;24(4):740-7. doi: 10.1038/leu.2009.289. Epub 2010 Jan 14.


HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis.

Liang M, Han X, Vadhan-Raj S, Nguyen M, Zhang YH, Fernandez M, Drakos E, Konoplev SN, Yin CC, Miranda RN, McDonnell TJ, Medeiros LJ, Bueso-Ramos CE.

Mod Pathol. 2010 Mar;23(3):381-91. doi: 10.1038/modpathol.2009.170. Epub 2010 Jan 8.


Theoretical study of Mg+-X and [X-Mg-Y]+ complexes important in the chemistry of ionospheric magnesium (X, Y = H2O, CO2, N2, O2, and O).

Plowright RJ, McDonnell TJ, Wright TG, Plane JM.

J Phys Chem A. 2009 Aug 20;113(33):9354-64. doi: 10.1021/jp905642h.


Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer.

Tsavachidou D, McDonnell TJ, Wen S, Wang X, Vakar-Lopez F, Pisters LL, Pettaway CA, Wood CG, Do KA, Thall PF, Stephens C, Efstathiou E, Taylor R, Menter DG, Troncoso P, Lippman SM, Logothetis CJ, Kim J.

J Natl Cancer Inst. 2009 Mar 4;101(5):306-20. doi: 10.1093/jnci/djn512. Epub 2009 Feb 24.


The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death.

Chari NS, Pinaire NL, Thorpe L, Medeiros LJ, Routbort MJ, McDonnell TJ.

Apoptosis. 2009 Apr;14(4):336-47. doi: 10.1007/s10495-009-0327-9. Review.


Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer.

McDonnell TJ, Chari NS, Cho-Vega JH, Troncoso P, Wang X, Bueso-Ramos CE, Coombes K, Brisbay S, Lopez R, Prendergast G, Logothetis C, Do KA.

BMC Med Genomics. 2008 Jan 31;1:1. doi: 10.1186/1755-8794-1-1.


Bilateral olecranon fracture as first presentation of sarcoidosis: case report and review of the literature.

O'Daly BJ, Harty JA, O'Malley N, Killeen R, McDonnell TJ, Quinlan WR.

J Shoulder Elbow Surg. 2008 Jul-Aug;17(4):e1-5. doi: 10.1016/j.jse.2007.06.016. Epub 2008 Jan 7. Review. No abstract available.


Dicarbonyl/L-xylulose reductase: a potential biomarker identified by laser-capture microdissection-micro serial analysis of gene expression of human prostate adenocarcinoma.

Cho-Vega JH, Tsavachidis S, Do KA, Nakagawa J, Medeiros LJ, McDonnell TJ.

Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2615-22.


Predicting altered pathways using extendable scaffolds.

Broom BM, McDonnell TJ, Subramanian D.

Int J Bioinform Res Appl. 2006;2(1):3-18.


The sonic hedgehog signaling network in development and neoplasia.

Chari NS, McDonnell TJ.

Adv Anat Pathol. 2007 Sep;14(5):344-52. Review.


Adverse reaction to Bacille-Calmette-Guérin vaccine in a HIV positive healthcare worker.

Garvey JF, Gueret P, McDonnell TJ.

Ir J Med Sci. 2007 Sep;176(3):237-8. Epub 2007 Aug 16.


Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.

Lee S, Chari NS, Kim HW, Wang X, Roop DR, Cho SH, DiGiovanni J, McDonnell TJ.

Mol Carcinog. 2007 Dec;46(12):949-57.


Does prior treatment with fumaric acid esters predispose to tuberculosis in patients on etanercept?

Ahmad K, McDonnell TJ, Rogers S.

Clin Exp Dermatol. 2007 May;32(3):329. No abstract available.


Initial modulation of the tumor microenvironment accounts for thalidomide activity in prostate cancer.

Efstathiou E, Troncoso P, Wen S, Do KA, Pettaway CA, Pisters LL, McDonnell TJ, Logothetis CJ.

Clin Cancer Res. 2007 Feb 15;13(4):1224-31.


Merging microarray data, robust feature selection, and predicting prognosis in prostate cancer.

Wang J, Do KA, Wen S, Tsavachidis S, McDonnell TJ, Logothetis CJ, Coombes KR.

Cancer Inform. 2007 Feb 14;2:87-97.


HDM4 (HDMX) is widely expressed in adult pre-B acute lymphoblastic leukemia and is a potential therapeutic target.

Han X, Garcia-Manero G, McDonnell TJ, Lozano G, Medeiros LJ, Xiao L, Rosner G, Nguyen M, Fernandez M, Valentin-Vega YA, Barboza J, Jones DM, Rassidakis GZ, Kantarjian HM, Bueso-Ramos CE.

Mod Pathol. 2007 Jan;20(1):54-62. Epub 2006 Nov 24.


Effectiveness of pulmonary rehabilitation in restrictive lung disease.

Naji NA, Connor MC, Donnelly SC, McDonnell TJ.

J Cardiopulm Rehabil. 2006 Jul-Aug;26(4):237-43.


Bcl-2 and bax expression and prostate cancer outcome in men treated with radiotherapy in Radiation Therapy Oncology Group protocol 86-10.

Khor LY, Desilvio M, Li R, McDonnell TJ, Hammond ME, Sause WT, Pilepich MV, Okunieff P, Sandler HM, Pollack A.

Int J Radiat Oncol Biol Phys. 2006 Sep 1;66(1):25-30. Epub 2006 Jul 11.


Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression.

Spurgers KB, Gold DL, Coombes KR, Bohnenstiehl NL, Mullins B, Meyn RE, Logothetis CJ, McDonnell TJ.

J Biol Chem. 2006 Sep 1;281(35):25134-42. Epub 2006 Jun 23.


Molecular mediators of cell death in multistep carcinogenesis: a path to targeted therapy.

Spurgers KB, Chari NS, Bohnenstiehl NL, McDonnell TJ.

Cell Death Differ. 2006 Aug;13(8):1360-70. Epub 2006 Jun 9. Review.


Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer.

Kim J, Sun P, Lam YW, Troncoso P, Sabichi AL, Babaian RJ, Pisters LL, Pettaway CA, Wood CG, Lippman SM, McDonnell TJ, Lieberman R, Logothetis C, Ho SM.

Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1697-702.


Protein expression of a triad of frequently methylated genes, p73, p57Kip2, and p15, has prognostic value in adult acute lymphocytic leukemia independently of its methylation status.

Bueso-Ramos C, Xu Y, McDonnell TJ, Brisbay S, Pierce S, Kantarjian H, Rosner G, Garcia-Manero G.

J Clin Oncol. 2005 Jun 10;23(17):3932-9. Epub 2005 Apr 25.


Immunosuppressant-responsive idiopathic lymphocytic pleuritis.

O'Connor TM, Haider W, Crotty T, McDonnell TJ, McNicholas WT.

Respiration. 2005 Mar-Apr;72(2):202-4.


Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes.

Bigelow RL, Jen EY, Delehedde M, Chari NS, McDonnell TJ.

J Invest Dermatol. 2005 Feb;124(2):457-65.


Combined laser capture microdissection and serial analysis of gene expression from human tissue samples.

Cho-Vega JH, Troncoso P, Do KA, Rago C, Wang X, Tsavachidis S, Medeiros LJ, Spurgers K, Logothetis C, McDonnell TJ.

Mod Pathol. 2005 Apr;18(4):577-84.

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