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Items: 18


Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus.

Quinodoz SA, Ollikainen N, Tabak B, Palla A, Schmidt JM, Detmar E, Lai MM, Shishkin AA, Bhat P, Takei Y, Trinh V, Aznauryan E, Russell P, Cheng C, Jovanovic M, Chow A, Cai L, McDonel P, Garber M, Guttman M.

Cell. 2018 Jul 26;174(3):744-757.e24. doi: 10.1016/j.cell.2018.05.024. Epub 2018 Jun 7.


Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon.

Donnard E, Vangala P, Afik S, McCauley S, Nowosielska A, Kucukural A, Tabak B, Zhu X, Diehl W, McDonel P, Yosef N, Luban J, Garber M.

Cell Syst. 2018 Mar 28;6(3):381-394.e7. doi: 10.1016/j.cels.2018.01.002. Epub 2018 Feb 14.


Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic.

Diehl WE, Lin AE, Grubaugh ND, Carvalho LM, Kim K, Kyawe PP, McCauley SM, Donnard E, Kucukural A, McDonel P, Schaffner SF, Garber M, Rambaut A, Andersen KG, Sabeti PC, Luban J.

Cell. 2016 Nov 3;167(4):1088-1098.e6. doi: 10.1016/j.cell.2016.10.014.


Local regulation of gene expression by lncRNA promoters, transcription and splicing.

Engreitz JM, Haines JE, Perez EM, Munson G, Chen J, Kane M, McDonel PE, Guttman M, Lander ES.

Nature. 2016 Nov 17;539(7629):452-455. doi: 10.1038/nature20149. Epub 2016 Oct 26.


Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing.

Chen CK, Blanco M, Jackson C, Aznauryan E, Ollikainen N, Surka C, Chow A, Cerase A, McDonel P, Guttman M.

Science. 2016 Oct 28;354(6311):468-472. Epub 2016 Aug 4.


Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits.

Ulirsch JC, Nandakumar SK, Wang L, Giani FC, Zhang X, Rogov P, Melnikov A, McDonel P, Do R, Mikkelsen TS, Sankaran VG.

Cell. 2016 Jun 2;165(6):1530-1545. doi: 10.1016/j.cell.2016.04.048.


Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.

Wakabayashi A, Ulirsch JC, Ludwig LS, Fiorini C, Yasuda M, Choudhuri A, McDonel P, Zon LI, Sankaran VG.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4434-9. doi: 10.1073/pnas.1521754113. Epub 2016 Apr 4.


Multiple cell and population-level interactions with mouse embryonic stem cell heterogeneity.

Cannon D, Corrigan AM, Miermont A, McDonel P, Chubb JR.

Development. 2015 Aug 15;142(16):2840-9. doi: 10.1242/dev.120741. Epub 2015 Jul 24.


The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M.

Nature. 2015 May 14;521(7551):232-6. doi: 10.1038/nature14443. Epub 2015 Apr 27.


RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.

Engreitz JM, Sirokman K, McDonel P, Shishkin AA, Surka C, Russell P, Grossman SR, Chow AY, Guttman M, Lander ES.

Cell. 2014 Sep 25;159(1):188-199. doi: 10.1016/j.cell.2014.08.018.


The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome.

Engreitz JM, Pandya-Jones A, McDonel P, Shishkin A, Sirokman K, Surka C, Kadri S, Xing J, Goren A, Lander ES, Plath K, Guttman M.

Science. 2013 Aug 16;341(6147):1237973. doi: 10.1126/science.1237973. Epub 2013 Jul 4.


Sin3a is essential for the genome integrity and viability of pluripotent cells.

McDonel P, Demmers J, Tan DW, Watt F, Hendrich BD.

Dev Biol. 2012 Mar 1;363(1):62-73. doi: 10.1016/j.ydbio.2011.12.019. Epub 2011 Dec 20.


Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development.

McDonel P, Costello I, Hendrich B.

Int J Biochem Cell Biol. 2009 Jan;41(1):108-16. doi: 10.1016/j.biocel.2008.07.022. Epub 2008 Aug 14. Review.


Clustered DNA motifs mark X chromosomes for repression by a dosage compensation complex.

McDonel P, Jans J, Peterson BK, Meyer BJ.

Nature. 2006 Nov 30;444(7119):614-8. Epub 2006 Nov 19.


Sex and X-chromosome-wide repression in Caenorhabditis elegans.

Meyer BJ, McDonel P, Csankovszki G, Ralston E.

Cold Spring Harb Symp Quant Biol. 2004;69:71-9. Review. No abstract available.


Recruitment and spreading of the C. elegans dosage compensation complex along X chromosomes.

Csankovszki G, McDonel P, Meyer BJ.

Science. 2004 Feb 20;303(5661):1182-5.


Phylogenetic relationships in Gleditsia (Leguminosae) based on ITS sequences.

Schnabel A, McDonel PE, Wendel JF.

Am J Bot. 2003 Feb;90(2):310-20. doi: 10.3732/ajb.90.2.310.


Evaluation of PCR-generated chimeras, mutations, and heteroduplexes with 16S rRNA gene-based cloning.

Qiu X, Wu L, Huang H, McDonel PE, Palumbo AV, Tiedje JM, Zhou J.

Appl Environ Microbiol. 2001 Feb;67(2):880-7.

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