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GAD65 antibodies and incident type 2 Diabetes mellitus.

Koopman ADM, Beulens JW, Voerman E, Rauh SP, van der Heijden AA, McDonald TJ, Gort M, Rutters F.

Metabolism. 2019 Mar 7. pii: S0026-0495(19)30049-6. doi: 10.1016/j.metabol.2019.03.001. [Epub ahead of print] Review.


Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study.

Kennedy NA, Heap GA, Green HD, Hamilton B, Bewshea C, Walker GJ, Thomas A, Nice R, Perry MH, Bouri S, Chanchlani N, Heerasing NM, Hendy P, Lin S, Gaya DR, Cummings JRF, Selinger CP, Lees CW, Hart AL, Parkes M, Sebastian S, Mansfield JC, Irving PM, Lindsay J, Russell RK, McDonald TJ, McGovern D, Goodhand JR, Ahmad T; UK Inflammatory Bowel Disease Pharmacogenetics Study Group.

Lancet Gastroenterol Hepatol. 2019 Feb 26. pii: S2468-1253(19)30012-3. doi: 10.1016/S2468-1253(19)30012-3. [Epub ahead of print]


Domestic Exposures to Polycyclic Aromatic Hydrocarbons in a Houston, Texas, Environmental Justice Neighborhood.

Sansom GT, Kirsch KR, Stone KW, McDonald TJ, Horney JA.

Environ Justice. 2018 Oct;11(5):183-191. doi: 10.1089/env.2018.0004. Epub 2018 Oct 16.


Splenic Embolization After Trauma: An Opportunity to Improve Best Immunization Practices.

Crooker KG, Howard JM, Alvarado AR, McDonald TJ, Berry SD, Green JL, Winfield RD.

J Surg Res. 2018 Dec;232:293-297. doi: 10.1016/j.jss.2018.06.036. Epub 2018 Jul 14.


Zinc Transporter 8 Autoantibodies (ZnT8A) and a Type 1 Diabetes Genetic Risk Score Can Exclude Individuals With Type 1 Diabetes From Inappropriate Genetic Testing for Monogenic Diabetes.

Patel KA, Weedon MN, Shields BM, Pearson ER, Hattersley AT, McDonald TJ; UNITED study team.

Diabetes Care. 2019 Feb;42(2):e16-e17. doi: 10.2337/dc18-0373. Epub 2018 Nov 8. No abstract available.


A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy.

Grubb AL, McDonald TJ, Rutters F, Donnelly LA, Hattersley AT, Oram RA, Palmer CNA, van der Heijden AA, Carr F, Elders PJM, Weedon MN, Slieker RC, 't Hart LM, Pearson ER, Shields BM, Jones AG.

Diabetes Care. 2019 Feb;42(2):208-214. doi: 10.2337/dc18-0431. Epub 2018 Oct 23.


Ketogenic Diets for Adult Neurological Disorders.

McDonald TJW, Cervenka MC.

Neurotherapeutics. 2018 Oct;15(4):1018-1031. doi: 10.1007/s13311-018-0666-8. Review.


Accelerated Oxidation of Organic Contaminants by Ferrate(VI): The Overlooked Role of Reducing Additives.

Feng M, Jinadatha C, McDonald TJ, Sharma VK.

Environ Sci Technol. 2018 Oct 2;52(19):11319-11327. doi: 10.1021/acs.est.8b03770. Epub 2018 Sep 18.


The governance structure for data access in the DIRECT consortium: an innovative medicines initiative (IMI) project.

Teare HJA, de Masi F, Banasik K, Barnett A, Herrgard S, Jablonka B, Postma JWM, McDonald TJ, Forgie I, Chmura PJ, Rydzka EK, Gupta R, Brunak S, Pearson E, Kaye J.

Life Sci Soc Policy. 2018 Sep 4;14(1):20. doi: 10.1186/s40504-018-0083-0.


The Expanding Role of Ketogenic Diets in Adult Neurological Disorders.

McDonald TJW, Cervenka MC.

Brain Sci. 2018 Aug 8;8(8). pii: E148. doi: 10.3390/brainsci8080148. Review.


Exocrine pancreatic dysfunction is common in hepatocyte nuclear factor 1β-associated renal disease and can be symptomatic.

Clissold RL, Fulford J, Hudson M, Shields BM, McDonald TJ, Ellard S, Hattersley AT, Bingham C.

Clin Kidney J. 2018 Aug;11(4):453-458. doi: 10.1093/ckj/sfx150. Epub 2018 Jan 30.


Improving compliance in adults with epilepsy on a modified Atkins diet: A randomized trial.

McDonald TJW, Henry-Barron BJ, Felton EA, Gutierrez EG, Barnett J, Fisher R, Lwin M, Jan A, Vizthum D, Kossoff EH, Cervenka MC.

Seizure. 2018 Aug;60:132-138. doi: 10.1016/j.seizure.2018.06.019. Epub 2018 Jun 22.


C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase.

Shields BM, McDonald TJ, Oram R, Hill A, Hudson M, Leete P, Pearson ER, Richardson SJ, Morgan NG, Hattersley AT; TIGI Consortium.

Diabetes Care. 2018 Jul;41(7):1486-1492. doi: 10.2337/dc18-0465. Epub 2018 Jun 7.


Determination of Thyreostats in Urine Using Supported Liquid Extraction and Mixed-Mode Cation-Exchange Solid-Phase Extraction: Screening and Confirmatory Methods.

Tölgyesi Á, Giri A, Barta E, McDonald TJ, Sharma VK.

J Chromatogr Sci. 2018 Oct 1;56(9):858-866. doi: 10.1093/chromsci/bmy054.


A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells.

Knight AR, Taylor EL, Lukaszewski R, Jensen KT, Jones HE, Carré JE, Isupov MN, Littlechild JA, Bailey SJ, Brewer E, McDonald TJ, Pitt AR, Spickett CM, Winyard PG.

Free Radic Biol Med. 2018 May 20;120:246-254. doi: 10.1016/j.freeradbiomed.2018.03.026. Epub 2018 Mar 17.


Comment on: "Dulaglutide treatment results in effective glycaemic control in latent autoimmune diabetes in adults (LADA): A post-hoc analysis of the AWARD-2, -4 and -5 trials".

Jones AG, McDonald TJ.

Diabetes Obes Metab. 2018 Jun;20(6):1549-1550. doi: 10.1111/dom.13290. Epub 2018 Apr 17. No abstract available.


Faecal calprotectin effectively excludes inflammatory bowel disease in 789 symptomatic young adults with/without alarm symptoms: a prospective UK primary care cohort study.

Walker GJ, Moore L, Heerasing N, Hendy P, Perry MH, McDonald TJ, Debenham T, Bethune R, Bewshea C, Hyde C, Heap GA, Singh A, Calvert C, Kennedy NA, Goodhand JR, Ahmad T.

Aliment Pharmacol Ther. 2018 Apr;47(8):1103-1116. doi: 10.1111/apt.14563. Epub 2018 Mar 5.


Comparing residential contamination in a Houston environmental justice neighborhood before and after Hurricane Harvey.

Horney JA, Casillas GA, Baker E, Stone KW, Kirsch KR, Camargo K, Wade TL, McDonald TJ.

PLoS One. 2018 Feb 8;13(2):e0192660. doi: 10.1371/journal.pone.0192660. eCollection 2018.


A type 1 diabetes genetic risk score can discriminate monogenic autoimmunity with diabetes from early-onset clustering of polygenic autoimmunity with diabetes.

Johnson MB, Patel KA, De Franco E, Houghton JAL, McDonald TJ, Ellard S, Flanagan SE, Hattersley AT.

Diabetologia. 2018 Apr;61(4):862-869. doi: 10.1007/s00125-018-4551-0. Epub 2018 Feb 7.


Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-term Glycemic Response to DPP-4 Inhibitor Therapy.

Dennis JM, Shields BM, Hill AV, Knight BA, McDonald TJ, Rodgers LR, Weedon MN, Henley WE, Sattar N, Holman RR, Pearson ER, Hattersley AT, Jones AG; MASTERMIND Consortium.

Diabetes Care. 2018 Apr;41(4):705-712. doi: 10.2337/dc17-1827. Epub 2018 Jan 31.


Impact of the modified Atkins diet on cardiovascular health in adults with epilepsy.

McDonald TJW, Ratchford EV, Henry-Barron BJ, Kossoff EH, Cervenka MC.

Epilepsy Behav. 2018 Feb;79:82-86. doi: 10.1016/j.yebeh.2017.10.035. Epub 2017 Dec 15.


Biological Limitations of Dechlorination of cis-Dichloroethene during Transport in Porous Media.

Mendoza-Sanchez I, Autenrieth RL, McDonald TJ, Cunningham JA.

Environ Sci Technol. 2018 Jan 16;52(2):684-691. doi: 10.1021/acs.est.7b04426. Epub 2017 Dec 28.


Ketogenic Diets for Adults With Highly Refractory Epilepsy.

McDonald TJW, Cervenka MC.

Epilepsy Curr. 2017 Nov-Dec;17(6):346-350. doi: 10.5698/1535-7597.17.6.346.


Occurrence, distribution and composition of aliphatic and polycyclic aromatic hydrocarbons in sediment cores from the Lower Fox River, Wisconsin, US.

Brewster CS, Sharma VK, Cizmas L, McDonald TJ.

Environ Sci Pollut Res Int. 2018 Feb;25(5):4974-4988. doi: 10.1007/s11356-017-0819-z. Epub 2017 Dec 5.


Random non-fasting C-peptide testing can identify patients with insulin-treated type 2 diabetes at high risk of hypoglycaemia.

Hope SV, Knight BA, Shields BM, Hill AV, Choudhary P, Strain WD, McDonald TJ, Jones AG.

Diabetologia. 2018 Jan;61(1):66-74. doi: 10.1007/s00125-017-4449-2. Epub 2017 Oct 5.


Assessment of toxicity of selenium and cadmium selenium quantum dots: A review.

Sharma VK, McDonald TJ, Sohn M, Anquandah GAK, Pettine M, Zboril R.

Chemosphere. 2017 Dec;188:403-413. doi: 10.1016/j.chemosphere.2017.08.130. Epub 2017 Aug 26. Review.


Screening and confirmation of steroids and nitroimidazoles in urine, blood, and food matrices: Sample preparation methods and liquid chromatography tandem mass spectrometric separations.

Tölgyesi Á, Barta E, Simon A, McDonald TJ, Sharma VK.

J Pharm Biomed Anal. 2017 Oct 25;145:805-813. doi: 10.1016/j.jpba.2017.08.005. Epub 2017 Aug 5.


Screening for neonatal diabetes at day 5 of life using dried blood spot glucose measurement.

McDonald TJ, Besser RE, Perry M, Babiker T, Knight BA, Shepherd MH, Ellard S, Flanagan SE, Hattersley AT.

Diabetologia. 2017 Nov;60(11):2168-2173. doi: 10.1007/s00125-017-4383-3. Epub 2017 Aug 5.


Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients.

Shields BM, Shepherd M, Hudson M, McDonald TJ, Colclough K, Peters J, Knight B, Hyde C, Ellard S, Pearson ER, Hattersley AT; UNITED study team.

Diabetes Care. 2017 Aug;40(8):1017-1025. doi: 10.2337/dc17-0224.


Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population.

Cichocki JA, Furuya S, Venkatratnam A, McDonald TJ, Knap AH, Wade T, Sweet S, Chiu WA, Threadgill DW, Rusyn I.

Environ Health Perspect. 2017 May 30;125(5):057006. doi: 10.1289/EHP788.


Impacts of Heronries on Water Quality as Evaluated through Escherichia coli and Fecal Sterol Analyses.

Telesford-Checkley JM, Mora MA, Gentry TJ, McDonald TJ, Boellstorff DE.

Water Environ Res. 2017 Jun 1;89(6):508-518. doi: 10.2175/106143017X14902968254430.


Determination of VH Family Usage in B-Cell Malignancies via the BIOMED-2 IGH PCR Clonality Assay.

McDonald TJ, Kuo L, Kuo FC.

Am J Clin Pathol. 2017 Jun 1;147(6):549-556. doi: 10.1093/ajcp/aqx007.


Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice.

Cichocki JA, Furuya S, Konganti K, Luo YS, McDonald TJ, Iwata Y, Chiu WA, Threadgill DW, Pogribny IP, Rusyn I.

J Pharmacol Exp Ther. 2017 Apr;361(1):17-28. doi: 10.1124/jpet.116.238790. Epub 2017 Feb 1.


Current laboratory requirements for adrenocorticotropic hormone and renin/aldosterone sample handling are unnecessarily restrictive.

Chakera AJ, McDonald TJ, Knight BA, Vaidya B, Jones AG.

Clin Med (Lond). 2017 Feb;17(1):18-21. doi: 10.7861/clinmedicine.17-1-18.


Low IgE Is a Useful Tool to Identify STAT3 Gain-of-Function Mutations.

Johnson MB, Flanagan SE, Martins TB, Hill HR, Hattersley AT, McDonald TJ.

Clin Chem. 2016 Nov;62(11):1536-1538. Epub 2016 Sep 8. No abstract available.


A cautionary tale: Unforeseen consequences of lean processing in a blood sciences laboratory.

Perry M, O'Connor J, James AJ, Cudmore AP, Lewis AV, Salzmann MB, McDonald TJ.

Clin Biochem. 2016 Nov;49(16-17):1311-1312. doi: 10.1016/j.clinbiochem.2016.08.011. Epub 2016 Aug 18. No abstract available.


Random non-fasting C-peptide: bringing robust assessment of endogenous insulin secretion to the clinic.

Hope SV, Knight BA, Shields BM, Hattersley AT, McDonald TJ, Jones AG.

Diabet Med. 2016 Nov;33(11):1554-1558. doi: 10.1111/dme.13142. Epub 2016 May 26.


Interleukin-1 antagonism in type 1 diabetes of long duration.

Seelig E, Timper K, Falconnier C, Stoeckli R, Bilz S, Oram R, McDonald TJ, Donath MY.

Diabetes Metab. 2016 Dec;42(6):453-456. doi: 10.1016/j.diabet.2016.08.005. Epub 2016 Oct 5. No abstract available.


Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.

Williams GM, Long AE, Wilson IV, Aitken RJ, Wyatt RC, McDonald TJ, Wong FS, Hattersley AT, Williams AJ, Bingley PJ, Gillespie KM.

Diabetologia. 2016 Dec;59(12):2722-2726. Epub 2016 Sep 3.


Clinical, functional, and surgical findings in chronic bilateral otitis media with effusion in childhood.

Diacova S, McDonald TJ, Ababii I.

Ear Nose Throat J. 2016 Aug;95(8):E31-7.


Systematic Population Screening, Using Biomarkers and Genetic Testing, Identifies 2.5% of the U.K. Pediatric Diabetes Population With Monogenic Diabetes.

Shepherd M, Shields B, Hammersley S, Hudson M, McDonald TJ, Colclough K, Oram RA, Knight B, Hyde C, Cox J, Mallam K, Moudiotis C, Smith R, Fraser B, Robertson S, Greene S, Ellard S, Pearson ER, Hattersley AT; UNITED Team.

Diabetes Care. 2016 Nov;39(11):1879-1888. Epub 2016 Jun 6.


Highly accurate molecular genetic testing for HFE hereditary hemochromatosis: results from 10 years of blinded proficiency surveys by the College of American Pathologists.

Press RD, Eickelberg G, McDonald TJ, Halley J, Long T, Tafe LJ, Weck KE.

Genet Med. 2016 Dec;18(12):1206-1213. doi: 10.1038/gim.2016.34. Epub 2016 Apr 28.


Detection of C-Peptide in Urine as a Measure of Ongoing Beta Cell Function.

McDonald TJ, Perry MH.

Methods Mol Biol. 2016;1433:93-102. doi: 10.1007/7651_2016_330.


Prenatal Exposure to Nitrosatable Drugs, Dietary Intake of Nitrites, and Preterm Birth.

Vuong AM, Shinde MU, Brender JD, Shipp EM, Huber JC Jr, Sharkey JR, McDonald TJ, Werler MM, Kelley KE, Griesenbeck JS, Langlois PH, Canfield MA; National Birth Defects Prevention Study Investigators.

Am J Epidemiol. 2016 Apr 1;183(7):634-42. doi: 10.1093/aje/kwv250. Epub 2016 Mar 6.


A review of the influence of treatment strategies on antibiotic resistant bacteria and antibiotic resistance genes.

Sharma VK, Johnson N, Cizmas L, McDonald TJ, Kim H.

Chemosphere. 2016 May;150:702-714. doi: 10.1016/j.chemosphere.2015.12.084. Epub 2016 Jan 13. Review.


Pharmaceuticals and personal care products in waters: occurrence, toxicity, and risk.

Cizmas L, Sharma VK, Gray CM, McDonald TJ.

Environ Chem Lett. 2015 Dec;13(4):381-394. doi: 10.1007/s10311-015-0524-4. Epub 2015 Aug 26.


A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults.

Oram RA, Patel K, Hill A, Shields B, McDonald TJ, Jones A, Hattersley AT, Weedon MN.

Diabetes Care. 2016 Mar;39(3):337-44. doi: 10.2337/dc15-1111. Epub 2015 Nov 17.


Maternal obesity disrupts the methionine cycle in baboon pregnancy.

Nathanielsz PW, Yan J, Green R, Nijland M, Miller JW, Wu G, McDonald TJ, Caudill MA.

Physiol Rep. 2015 Nov;3(11). pii: e12564. doi: 10.14814/phy2.12564.


Magnetic graphene-carbon nanotube iron nanocomposites as adsorbents and antibacterial agents for water purification.

Sharma VK, McDonald TJ, Kim H, Garg VK.

Adv Colloid Interface Sci. 2015 Nov;225:229-40. doi: 10.1016/j.cis.2015.10.006. Epub 2015 Oct 22. Review.


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