Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 489

1.

A large impact crater beneath Hiawatha Glacier in northwest Greenland.

Kjær KH, Larsen NK, Binder T, Bjørk AA, Eisen O, Fahnestock MA, Funder S, Garde AA, Haack H, Helm V, Houmark-Nielsen M, Kjeldsen KK, Khan SA, Machguth H, McDonald I, Morlighem M, Mouginot J, Paden JD, Waight TE, Weikusat C, Willerslev E, MacGregor JA.

Sci Adv. 2018 Nov 14;4(11):eaar8173. doi: 10.1126/sciadv.aar8173. eCollection 2018 Nov.

2.

Unlocking P(V): Reagents for chiral phosphorothioate synthesis.

Knouse KW, deGruyter JN, Schmidt MA, Zheng B, Vantourout JC, Kingston C, Mercer SE, Mcdonald IM, Olson RE, Zhu Y, Hang C, Zhu J, Yuan C, Wang Q, Park P, Eastgate MD, Baran PS.

Science. 2018 Sep 21;361(6408):1234-1238. doi: 10.1126/science.aau3369. Epub 2018 Aug 2.

PMID:
30072577
3.

Microbial biogeography of 925 geothermal springs in New Zealand.

Power JF, Carere CR, Lee CK, Wakerley GLJ, Evans DW, Button M, White D, Climo MD, Hinze AM, Morgan XC, McDonald IR, Cary SC, Stott MB.

Nat Commun. 2018 Jul 23;9(1):2876. doi: 10.1038/s41467-018-05020-y.

4.

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth.

Krulikas LJ, McDonald IM, Lee B, Okumu DO, East MP, Gilbert TSK, Herring LE, Golitz BT, Wells CI, Axtman AD, Zuercher WJ, Willson TM, Kireev D, Yeh JJ, Johnson GL, Baines AT, Graves LM.

SLAS Discov. 2018 Sep;23(8):850-861. doi: 10.1177/2472555218773045. Epub 2018 May 9.

PMID:
29742358
5.

Total Synthesis of (±)-Phomoidride D.

Leung JC, Bedermann AA, Njardarson JT, Spiegel DA, Murphy GK, Hama N, Twenter BM, Dong P, Shirahata T, McDonald IM, Inoue M, Taniguchi N, McMahon TC, Schneider CM, Tao N, Stoltz BM, Wood JL.

Angew Chem Int Ed Engl. 2018 Feb 12;57(7):1991-1994. doi: 10.1002/anie.201712369. Epub 2018 Jan 17.

PMID:
29286556
6.

Prior exposure to non-pathogenic calicivirus RCV-A1 reduces both infection rate and mortality from rabbit haemorrhagic disease in a population of wild rabbits in Australia.

Cooke BD, Duncan RP, McDonald I, Liu J, Capucci L, Mutze GJ, Strive T.

Transbound Emerg Dis. 2018 Apr;65(2):e470-e477. doi: 10.1111/tbed.12786. Epub 2017 Dec 17.

PMID:
29250929
7.

Design and synthesis of a novel series of (1'S,2R,4'S)-3H-4'-azaspiro[benzo[4,5]imidazo[2,1-b]oxazole-2,2'-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor.

Cook J, Zusi FC, Hill MD, Fang H, Pearce B, Park H, Gallagher L, McDonald IM, Bristow L, Macor JE, Olson RE.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):5002-5005. doi: 10.1016/j.bmcl.2017.10.009. Epub 2017 Oct 10.

PMID:
29050783
8.

Measuring Kinase Activity-A Global Challenge.

Cann ML, McDonald IM, East MP, Johnson GL, Graves LM.

J Cell Biochem. 2017 Nov;118(11):3595-3606. doi: 10.1002/jcb.26103. Epub 2017 May 31. Review.

PMID:
28464261
9.

Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents.

Pieschl RL, Miller R, Jones KM, Post-Munson DJ, Chen P, Newberry K, Benitex Y, Molski T, Morgan D, McDonald IM, Macor JE, Olson RE, Asaka Y, Digavalli S, Easton A, Herrington J, Westphal RS, Lodge NJ, Zaczek R, Bristow LJ, Li YW.

Eur J Pharmacol. 2017 Jul 15;807:1-11. doi: 10.1016/j.ejphar.2017.04.024. Epub 2017 Apr 22.

PMID:
28438647
10.

BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.

King D, Iwuagwu C, Cook J, McDonald IM, Mate R, Zusi FC, Hill MD, Fang H, Zhao R, Wang B, Easton AE, Miller R, Post-Munson D, Knox RJ, Gallagher L, Westphal R, Molski T, Fan J, Clarke W, Benitex Y, Lentz KA, Denton R, Morgan D, Zaczek R, Lodge NJ, Bristow LJ, Macor JE, Olson RE.

ACS Med Chem Lett. 2017 Feb 8;8(3):366-371. doi: 10.1021/acsmedchemlett.7b00032. eCollection 2017 Mar 9.

11.

Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals.

Arend KC, Lenarcic EM, Vincent HA, Rashid N, Lazear E, McDonald IM, Gilbert TS, East MP, Herring LE, Johnson GL, Graves LM, Moorman NJ.

Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S263-S276. doi: 10.1074/mcp.M116.065375. Epub 2017 Feb 25.

12.

Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR.

Iwuagwu C, King D, McDonald IM, Cook J, Zusi FC, Hill MD, Mate RA, Fang H, Knox R, Gallagher L, Post-Munson Amy Easton D, Miller R, Benitex Y, Siuciak J, Lodge N, Zaczek R, Morgan D, Bristow L, Macor JE, Olson RE.

Bioorg Med Chem Lett. 2017 Mar 1;27(5):1261-1266. doi: 10.1016/j.bmcl.2017.01.058. Epub 2017 Jan 20.

PMID:
28169167
13.

B-973, a novel piperazine positive allosteric modulator of the α7 nicotinic acetylcholine receptor.

Post-Munson DJ, Pieschl RL, Molski TF, Graef JD, Hendricson AW, Knox RJ, McDonald IM, Olson RE, Macor JE, Weed MR, Bristow LJ, Kiss L, Ahlijanian MK, Herrington J.

Eur J Pharmacol. 2017 Mar 15;799:16-25. doi: 10.1016/j.ejphar.2017.01.037. Epub 2017 Jan 26.

PMID:
28132910
14.

Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists.

Hill MD, Fang H, King HD, Iwuagwu CI, McDonald IM, Cook J, Zusi FC, Mate RA, Knox RJ, Post-Munson D, Easton A, Miller R, Lentz K, Clarke W, Benitex Y, Lodge N, Zaczek R, Denton R, Morgan D, Bristow L, Macor JE, Olson R.

ACS Med Chem Lett. 2016 Dec 1;8(1):133-137. doi: 10.1021/acsmedchemlett.6b00471. eCollection 2017 Jan 12.

15.

Microbial community dynamics in Inferno Crater Lake, a thermally fluctuating geothermal spring.

Ward L, Taylor MW, Power JF, Scott BJ, McDonald IR, Stott MB.

ISME J. 2017 May;11(5):1158-1167. doi: 10.1038/ismej.2016.193. Epub 2017 Jan 10.

16.

Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship.

Cook J, Zusi FC, McDonald IM, King D, Hill MD, Iwuagwu C, Mate RA, Fang H, Zhao R, Wang B, Cutrone J, Ma B, Gao Q, Knox RJ, Matchett M, Gallagher L, Ferrante M, Post-Munson D, Molski T, Easton A, Miller R, Jones K, Digavalli S, Healy F, Lentz K, Benitex Y, Clarke W, Natale J, Siuciak JA, Lodge N, Zaczek R, Denton R, Morgan D, Bristow LJ, Macor JE, Olson RE.

J Med Chem. 2016 Dec 22;59(24):11171-11181. doi: 10.1021/acs.jmedchem.6b01506. Epub 2016 Dec 13.

PMID:
27958732
17.

The Chthonomonas calidirosea Genome Is Highly Conserved across Geographic Locations and Distinct Chemical and Microbial Environments in New Zealand's Taupō Volcanic Zone.

Lee KC, Stott MB, Dunfield PF, Huttenhower C, McDonald IR, Morgan XC.

Appl Environ Microbiol. 2016 May 31;82(12):3572-81. doi: 10.1128/AEM.00139-16. Print 2016 Jun 15.

18.

'Venus trapped, Mars transits': Cu and Fe redox chemistry, cellular topography and in situ ligand binding in terrestrial isopod hepatopancreas.

Kille P, Morgan AJ, Powell K, Mosselmans JF, Hart D, Gunning P, Hayes A, Scarborough D, McDonald I, Charnock JM.

Open Biol. 2016 Mar;6(3). pii: 150270. doi: 10.1098/rsob.150270.

19.

General Method for the Preparation of Electron-Deficient Imidazo[1,2-a]pyridines and Related Heterocycles.

McDonald IM, Peese KM.

Org Lett. 2015 Dec 18;17(24):6002-5. doi: 10.1021/acs.orglett.5b02966. Epub 2015 Nov 24.

PMID:
26598965
20.

Thermorudis pharmacophila sp. nov., a novel member of the class Thermomicrobia isolated from geothermal soil, and emended descriptions of Thermomicrobium roseum, Thermomicrobium carboxidum, Thermorudis peleae and Sphaerobacter thermophilus.

Houghton KM, Morgan XC, Lagutin K, MacKenzie AD, Vyssotskii M, Mitchell KA, McDonald IR, Morgan HW, Power JF, Moreau JW, Hanssen E, Stott MB.

Int J Syst Evol Microbiol. 2015 Dec;65(12):4479-87. doi: 10.1099/ijsem.0.000598. Epub 2015 Sep 14.

PMID:
26374291
21.

Whole-Retina Reduced Electrophysiological Activity in Mice Bearing Retina-Specific Deletion of Vesicular Acetylcholine Transporter.

Bedore J, Martyn AC, Li AK, Dolinar EA, McDonald IS, Coupland SG, Prado VF, Prado MA, Hill KA.

PLoS One. 2015 Jul 30;10(7):e0133989. doi: 10.1371/journal.pone.0133989. eCollection 2015.

22.

Benthic microbial communities of coastal terrestrial and ice shelf Antarctic meltwater ponds.

Archer SD, McDonald IR, Herbold CW, Lee CK, Cary CS.

Front Microbiol. 2015 May 27;6:485. doi: 10.3389/fmicb.2015.00485. eCollection 2015.

23.

Role of cytokines and chemokines in itch.

Storan ER, O'Gorman SM, McDonald ID, Steinhoff M.

Handb Exp Pharmacol. 2015;226:163-76. doi: 10.1007/978-3-662-44605-8_9. Review.

PMID:
25861779
24.

Molecular and Morphological Characterization of Inflammatory Infiltrate in Rosacea Reveals Activation of Th1/Th17 Pathways.

Buhl T, Sulk M, Nowak P, Buddenkotte J, McDonald I, Aubert J, Carlavan I, Déret S, Reiniche P, Rivier M, Voegel JJ, Steinhoff M.

J Invest Dermatol. 2015 Sep;135(9):2198-2208. doi: 10.1038/jid.2015.141. Epub 2015 Apr 7.

25.

Blistering psoriatic plaques during narrowband UVB phototherapy.

Fahy CM, McDonald I, Gaynor L, Murphy GM, Mulligan N, Lenane P, Moloney FJ.

Photodermatol Photoimmunol Photomed. 2015 May;31(3):167-9. doi: 10.1111/phpp.12167. Epub 2015 Mar 3. No abstract available.

PMID:
25684540
26.

Straightforward assay for quantification of social avoidance in Drosophila melanogaster.

Fernandez RW, Nurilov M, Feliciano O, McDonald IS, Simon AF.

J Vis Exp. 2014 Dec 13;(94). doi: 10.3791/52011.

27.

Vismodegib in the treatment of advanced BCC.

O'Kane GM, Lyons T, McDonald I, Mulligan N, Moloney FJ, Murray D, Kelly CM.

Ir Med J. 2014 Jul-Aug;107(7):215-6.

PMID:
25226719
28.

Tandem ring-closing metathesis/transfer hydrogenation: practical chemoselective hydrogenation of alkenes.

Connolly T, Wang Z, Walker MA, McDonald IM, Peese KM.

Org Lett. 2014 Sep 5;16(17):4444-7. doi: 10.1021/ol5019739. Epub 2014 Aug 20.

PMID:
25140991
29.

Parenteral administration of GnRH constructs and adjuvants: immune responses and effects on reproductive tissues of male mice.

Sharma S, McDonald I, Miller L, Hinds LA.

Vaccine. 2014 Sep 29;32(43):5555-63. doi: 10.1016/j.vaccine.2014.07.075. Epub 2014 Aug 15.

PMID:
25130539
30.

Characterisation of bacterioplankton communities in the meltwater ponds of Bratina Island, Victoria Land, Antarctica.

Archer SD, McDonald IR, Herbold CW, Cary SC.

FEMS Microbiol Ecol. 2014 Aug;89(2):451-64. doi: 10.1111/1574-6941.12358. Epub 2014 Jun 17.

31.

Evidence of global-scale aeolian dispersal and endemism in isolated geothermal microbial communities of Antarctica.

Herbold CW, Lee CK, McDonald IR, Cary SC.

Nat Commun. 2014 May 20;5:3875. doi: 10.1038/ncomms4875.

PMID:
24846491
32.

Effect of long-term starvation on the survival, recovery, and carbon utilization profiles of a bovine Escherichia coli O157:H7 isolate from New Zealand.

Xavier RN, Morgan HW, McDonald IR, Withers H.

Appl Environ Microbiol. 2014 Jul;80(14):4383-90. doi: 10.1128/AEM.00045-14. Epub 2014 May 9.

33.

Influence of soil properties on archaeal diversity and distribution in the McMurdo Dry Valleys, Antarctica.

Richter I, Herbold CW, Lee CK, McDonald IR, Barrett JE, Cary SC.

FEMS Microbiol Ecol. 2014 Aug;89(2):347-59. doi: 10.1111/1574-6941.12322. Epub 2014 Apr 16.

34.

Genomic analysis of Chthonomonas calidirosea, the first sequenced isolate of the phylum Armatimonadetes.

Lee KC, Morgan XC, Dunfield PF, Tamas I, McDonald IR, Stott MB.

ISME J. 2014 Jul;8(7):1522-33. doi: 10.1038/ismej.2013.251. Epub 2014 Jan 30.

35.

A Reproductive Management Program for an Urban Population of Eastern Grey Kangaroos (Macropus giganteus).

Tribe A, Hanger J, McDonald IJ, Loader J, Nottidge BJ, McKee JJ, Phillips CJ.

Animals (Basel). 2014 Sep 15;4(3):562-82. doi: 10.3390/ani4030562.

36.

Effect of alpha7 nicotinic acetylcholine receptor agonists on attentional set-shifting impairment in rats.

Jones KM, McDonald IM, Bourin C, Olson RE, Bristow LJ, Easton A.

Psychopharmacology (Berl). 2014 Feb;231(4):673-83. doi: 10.1007/s00213-013-3275-6. Epub 2013 Sep 21.

PMID:
24057763
37.

PXS-4681A, a potent and selective mechanism-based inhibitor of SSAO/VAP-1 with anti-inflammatory effects in vivo.

Foot JS, Yow TT, Schilter H, Buson A, Deodhar M, Findlay AD, Guo L, McDonald IA, Turner CI, Zhou W, Jarolimek W.

J Pharmacol Exp Ther. 2013 Nov;347(2):365-74. doi: 10.1124/jpet.113.207613. Epub 2013 Aug 13.

38.

Maximal extent of translocation of single-walled carbon nanotubes from lung airways of the rat.

Matthews IP, Gregory CJ, Aljayyoussi G, Morris CJ, McDonald I, Hoogendoorn B, Gumbleton M.

Environ Toxicol Pharmacol. 2013 May;35(3):461-4. doi: 10.1016/j.etap.2013.02.002. Epub 2013 Feb 20.

PMID:
23501606
39.

Discovery of a novel series of quinolone α7 nicotinic acetylcholine receptor agonists.

McDonald IM, Mate RA, Zusi FC, Huang H, Post-Munson DJ, Ferrante MA, Gallagher L, Bertekap RL Jr, Knox RJ, Robertson BJ, Harden DG, Morgan DG, Lodge NJ, Dworetzky SI, Olson RE, Macor JE.

Bioorg Med Chem Lett. 2013 Mar 15;23(6):1684-8. doi: 10.1016/j.bmcl.2013.01.070. Epub 2013 Jan 29.

PMID:
23414838
40.

Phylogenetic delineation of the novel phylum Armatimonadetes (former candidate division OP10) and definition of two novel candidate divisions.

Lee KC, Herbold CW, Dunfield PF, Morgan XC, McDonald IR, Stott MB.

Appl Environ Microbiol. 2013 Apr;79(7):2484-7. doi: 10.1128/AEM.03333-12. Epub 2013 Feb 1.

41.

Toward the synthesis of phomoidride D.

Murphy GK, Shirahata T, Hama N, Bedermann A, Dong P, McMahon TC, Twenter BM, Spiegel DA, McDonald IM, Taniguchi N, Inoue M, Wood JL.

J Org Chem. 2013 Jan 18;78(2):477-89. doi: 10.1021/jo302353g. Epub 2013 Jan 10.

PMID:
23245580
42.

Groundtruthing next-gen sequencing for microbial ecology-biases and errors in community structure estimates from PCR amplicon pyrosequencing.

Lee CK, Herbold CW, Polson SW, Wommack KE, Williamson SJ, McDonald IR, Cary SC.

PLoS One. 2012;7(9):e44224. doi: 10.1371/journal.pone.0044224. Epub 2012 Sep 6.

43.

Outcomes and patterns of infections in patients with underlying haematological malignancies admitted to intensive care.

José RJ, Pfeffer PE, McDonald I, Shaw S, Padate B, McNamara C, Kibbler C, Agarwal B.

Br J Anaesth. 2012 Aug;109(2):291-2. doi: 10.1093/bja/aes242. No abstract available.

44.

Diversity of methyl halide-degrading microorganisms in oceanic and coastal waters.

Cox MJ, Schäfer H, Nightingale PD, McDonald IR, Murrell JC.

FEMS Microbiol Lett. 2012 Sep;334(2):111-8. doi: 10.1111/j.1574-6968.2012.02624.x. Epub 2012 Jul 9.

45.

A review of psoriasis, a known risk factor for cardiovascular disease and its impact on folate and homocysteine metabolism.

McDonald I, Connolly M, Tobin AM.

J Nutr Metab. 2012;2012:965385. doi: 10.1155/2012/965385. Epub 2012 May 29.

46.

The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1).

Foot JS, Deodhar M, Turner CI, Yin P, van Dam EM, Silva DG, Olivieri A, Holt A, McDonald IA.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):3935-40. doi: 10.1016/j.bmcl.2012.04.111. Epub 2012 Apr 30.

PMID:
22595173
47.

Electing a candidate: a speculative history of the bacterial phylum OP10.

Dunfield PF, Tamas I, Lee KC, Morgan XC, McDonald IR, Stott MB.

Environ Microbiol. 2012 Dec;14(12):3069-80. doi: 10.1111/j.1462-2920.2012.02742.x. Epub 2012 Apr 13.

PMID:
22497633
48.

Evaluation of lactic acid bacterium from chilli waste as a potential antifungal agent for wood products.

O'Callahan DR, Singh T, McDonald IR.

J Appl Microbiol. 2012 Mar;112(3):436-42. doi: 10.1111/j.1365-2672.2011.05226.x.

49.

Rapid microbial response to the presence of an ancient relic in the Antarctic Dry Valleys.

Tiao G, Lee CK, McDonald IR, Cowan DA, Cary SC.

Nat Commun. 2012 Feb 7;3:660. doi: 10.1038/ncomms1645.

PMID:
22314356
50.

Identifying acute coronary syndromes from a single measure of plasma lipids?

McDonald I.

Eur Heart J. 2011 Nov;32(22):2727-8. No abstract available.

PMID:
22195297

Supplemental Content

Loading ...
Support Center