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Items: 40

1.

Phase I study of the novel Cdc2/CDK1 and AKT inhibitor terameprocol in patients with advanced leukemias.

Tibes R, McDonagh KT, Lekakis L, Bogenberger JM, Kim S, Frazer N, Mohrland S, Bassett D, Garcia R, Schroeder K, Shanmugam V, Carpten J, Hagelstrom RT, Beaudry C, Von Hoff D, Shea TC.

Invest New Drugs. 2015 Apr;33(2):389-96. doi: 10.1007/s10637-014-0198-y. Epub 2014 Dec 19.

PMID:
25523151
2.

Phase I study of MLN8237--investigational Aurora A kinase inhibitor--in relapsed/refractory multiple myeloma, non-Hodgkin lymphoma and chronic lymphocytic leukemia.

Kelly KR, Shea TC, Goy A, Berdeja JG, Reeder CB, McDonagh KT, Zhou X, Danaee H, Liu H, Ecsedy JA, Niu H, Benaim E, Iyer SP.

Invest New Drugs. 2014 Jun;32(3):489-99. doi: 10.1007/s10637-013-0050-9. Epub 2013 Dec 20.

3.

The reversal of inhibitors in congenital hemophilia.

DeFrates SR, McDonagh KT, Adams VR.

Pharmacotherapy. 2013 Feb;33(2):157-64. doi: 10.1002/phar.1173. Epub 2013 Jan 25. Review.

PMID:
23355059
4.

An open-label, single-arm, phase 2 (PX-171-004) study of single-agent carfilzomib in bortezomib-naive patients with relapsed and/or refractory multiple myeloma.

Vij R, Wang M, Kaufman JL, Lonial S, Jakubowiak AJ, Stewart AK, Kukreti V, Jagannath S, McDonagh KT, Alsina M, Bahlis NJ, Reu FJ, Gabrail NY, Belch A, Matous JV, Lee P, Rosen P, Sebag M, Vesole DH, Kunkel LA, Wear SM, Wong AF, Orlowski RZ, Siegel DS.

Blood. 2012 Jun 14;119(24):5661-70. doi: 10.1182/blood-2012-03-414359. Epub 2012 May 3.

5.

Identifying grant funding: mentored career development and transition awards.

McDonagh KT.

Hematology Am Soc Hematol Educ Program. 2008:12-5. doi: 10.1182/asheducation-2008.1.12.

PMID:
19074047
6.

Genetically engineered T cells expressing a HER2-specific chimeric receptor mediate antigen-specific tumor regression.

Li S, Yang J, Urban FA, MacGregor JN, Hughes DP, Chang AE, McDonagh KT, Li Q.

Cancer Gene Ther. 2008 Jun;15(6):382-92. doi: 10.1038/cgt.2008.5. Epub 2008 Feb 22.

PMID:
18292797
7.

High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study.

Nash RA, McSweeney PA, Crofford LJ, Abidi M, Chen CS, Godwin JD, Gooley TA, Holmberg L, Henstorf G, LeMaistre CF, Mayes MD, McDonagh KT, McLaughlin B, Molitor JA, Nelson JL, Shulman H, Storb R, Viganego F, Wener MH, Seibold JR, Sullivan KM, Furst DE.

Blood. 2007 Aug 15;110(4):1388-96. Epub 2007 Apr 23.

8.
9.

Fate and function of anti-CD3/CD28-activated T cells following adoptive transfer: IL-2 promotes development of anti-tumor memory T cells in vivo.

Hughes DP, Baskar D, Urban FF, Friedman MS, Braun TM, McDonagh KT.

Cytotherapy. 2005;7(5):396-407.

PMID:
16236629
10.

Essential erbB family phosphorylation in osteosarcoma as a target for CI-1033 inhibition.

Hughes DP, Thomas DG, Giordano TJ, McDonagh KT, Baker LH.

Pediatr Blood Cancer. 2006 May 1;46(5):614-23. Erratum in: Pediatr Blood Cancer. 2013 Jan;60(1):169.

12.

[Chimeric T cell receptor N29gamma redirect T lymphocytes response specific to p185HER2 in A murine model of metastatic breast cancer].

Li SP, Urban FA, Macgregor JN, Hughes DP, McDonagh KT.

Ai Zheng. 2004 Nov;23(11 Suppl):1370-5. Chinese.

PMID:
15566639
13.

MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix.

Chun TH, Sabeh F, Ota I, Murphy H, McDonagh KT, Holmbeck K, Birkedal-Hansen H, Allen ED, Weiss SJ.

J Cell Biol. 2004 Nov 22;167(4):757-67. Epub 2004 Nov 15.

14.

Adenovirus binding to cultured synoviocytes triggers signaling through MAPK pathways and induces expression of cyclooxygenase-2.

Crofford LJ, McDonagh KT, Guo S, Mehta H, Bian H, Petruzelli LM, Roessler BJ.

J Gene Med. 2005 Mar;7(3):288-96.

15.

Cell surface expression of epidermal growth factor receptor and Her-2 with nuclear expression of Her-4 in primary osteosarcoma.

Hughes DP, Thomas DG, Giordano TJ, Baker LH, McDonagh KT.

Cancer Res. 2004 Mar 15;64(6):2047-53. Erratum in: Cancer Res. 2013 Jul 1;73(13):4169.

16.

Gene therapy in tissue-engineered blood vessels.

Fields RC, Solan A, McDonagh KT, Niklason LE, Lawson JH.

Tissue Eng. 2003 Dec;9(6):1281-7.

17.

Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases.

Nash RA, Dansey R, Storek J, Georges GE, Bowen JD, Holmberg LA, Kraft GH, Mayes MD, McDonagh KT, Chen CS, Dipersio J, Lemaistre CF, Pavletic S, Sullivan KM, Sunderhaus J, Furst DE, McSweeney PA.

Biol Blood Marrow Transplant. 2003 Sep;9(9):583-91.

18.

Antigen-specific tumor vaccine efficacy in vivo against prostate cancer with low class I MHC requires competent class II MHC.

Neeley YC, McDonagh KT, Overwijk WW, Restifo NP, Sanda MG.

Prostate. 2002 Nov 1;53(3):183-91.

19.

High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes.

McSweeney PA, Nash RA, Sullivan KM, Storek J, Crofford LJ, Dansey R, Mayes MD, McDonagh KT, Nelson JL, Gooley TA, Holmberg LA, Chen CS, Wener MH, Ryan K, Sunderhaus J, Russell K, Rambharose J, Storb R, Furst DE.

Blood. 2002 Sep 1;100(5):1602-10.

20.

Highly efficient genetic transduction of primary human synoviocytes with concentrated retroviral supernatant.

Yang J, Friedman MS, Bian H, Crofford LJ, Roessler B, McDonagh KT.

Arthritis Res. 2002;4(3):215-9. Epub 2002 Feb 28.

21.

Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis.

Morita Y, Yang J, Gupta R, Shimizu K, Shelden EA, Endres J, Mulé JJ, McDonagh KT, Fox DA.

J Clin Invest. 2001 May;107(10):1275-84.

22.

Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors. A report of four cases.

Crofford LJ, Oates JC, McCune WJ, Gupta S, Kaplan MJ, Catella-Lawson F, Morrow JD, McDonagh KT, Schmaier AH.

Arthritis Rheum. 2000 Aug;43(8):1891-6.

23.

Retrovirus mediated gene transfer of the self antigen MBP into the bone marrow of mice alters resistance to experimental autoimmune encephalomyelitis.

Peters TR, Bodine DM, McDonagh KT, Lovett-Racke A, McFarland HF, McFarlin DE, Nienhuis AW, Racke MK.

J Neuroimmunol. 2000 Feb 1;103(1):51-62.

PMID:
10674989
24.
25.

Dendritic cell-based vaccines in the setting of peripheral blood stem cell transplantation: CD34+ cell-depleted mobilized peripheral blood can serve as a source of potent dendritic cells.

Choi D, Perrin M, Hoffmann S, Chang AE, Ratanatharathorn V, Uberti J, McDonagh KT, Mulé JJ.

Clin Cancer Res. 1998 Nov;4(11):2709-16.

26.
27.

Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial.

Collins AF, Pearson HA, Giardina P, McDonagh KT, Brusilow SW, Dover GJ.

Blood. 1995 Jan 1;85(1):43-9.

28.

Retroviral mediated transfer of the human multidrug resistance gene (MDR-1) into hematopoietic stem cells during autologous transplantation after intensive chemotherapy for metastatic breast cancer.

O'Shaughnessy JA, Cowan KH, Nienhuis AW, McDonagh KT, Sorrentino BP, Dunbar CE, Chiang Y, Wilson W, Goldspiel B, Kohler D, et al.

Hum Gene Ther. 1994 Jul;5(7):891-911.

PMID:
7526902
29.

Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate.

McDonagh KT, Dover GJ, Donahue RE, Nathan DG, Agricola B, Byrne E, Nienhuis AW.

Exp Hematol. 1992 Nov;20(10):1156-64.

PMID:
1385194
30.

Upstream sequences within the terminal hairpin positively regulate the P6 promoter of B19 parvovirus.

Liu JM, Green SW, Hao YS, McDonagh KT, Young NS, Shimada T.

Virology. 1991 Nov;185(1):39-47.

PMID:
1926783
31.

The upstream region of the human gamma-globin gene promoter. Identification and functional analysis of nuclear protein binding sites.

McDonagh KT, Lin HJ, Lowrey CH, Bodine DM, Nienhuis AW.

J Biol Chem. 1991 Jun 25;266(18):11965-74.

32.

Gene transfer into hematopoietic stem cells.

Nienhuis AW, McDonagh KT, Bodine DM.

Cancer. 1991 May 15;67(10 Suppl):2700-4. Review.

PMID:
2015571
33.

Survival and retrovirus infection of murine hematopoietic stem cells in vitro: effects of 5-FU and method of infection.

Bodine DM, McDonagh KT, Seidel NE, Nienhuis AW.

Exp Hematol. 1991 Mar;19(3):206-12.

PMID:
1704844
34.
35.

Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.

Bodine DM, McDonagh KT, Brandt SJ, Ney PA, Agricola B, Byrne E, Nienhuis AW.

Proc Natl Acad Sci U S A. 1990 May;87(10):3738-42.

36.
37.

Transcriptional regulation of human gamma globin gene expression.

McDonagh KT, Lin H, Bodine DM, Lowrey C, Purucker M, Ley T, Nienhuis AW.

Prog Clin Biol Res. 1989;316A:149-62. No abstract available.

PMID:
2594803
38.

Manipulation of HbF production with hematopoietic growth factors.

McDonagh KT, Dover GJ, Donahue R, Nathan DG, Nienhuis AW.

Prog Clin Biol Res. 1989;316B:307-15. No abstract available.

PMID:
2482500
39.

Regulatory regions flanking the human fetal gamma-globin genes.

Lin HJ, Bodine DM, Rutherford TR, Anagnou NP, McDonagh KT, Ley TJ, Nienhuis AW.

Ann N Y Acad Sci. 1989;565:13-22. No abstract available.

PMID:
2476058
40.

First example of familial posttransfusion purpura in two PlA1-negative sisters.

Chaplin H, Aster RH, Morgan LK, Horn B, McDonagh KT, Baskin R.

Transfusion. 1988 Jul-Aug;28(4):326-9.

PMID:
3388478

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