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Items: 1 to 50 of 67


Development of a cytology-based multivariate analytical risk index for oral cancer.

Abram TJ, Floriano PN, James R, Kerr AR, Thornhill MH, Redding SW, Vigneswaran N, Raja R, McRae MP, McDevitt JT.

Oral Oncol. 2019 May;92:6-11. doi: 10.1016/j.oraloncology.2019.02.011. Epub 2019 Mar 13.


Sensors that Learn: The Evolution from Taste Fingerprints to Patterns of Early Disease Detection.

Christodoulides N, McRae MP, Simmons GW, Modak SS, McDevitt JT.

Micromachines (Basel). 2019 Apr 16;10(4). pii: E251. doi: 10.3390/mi10040251. Review.


Risk Stratification of Oral Potentially Malignant Disorders in Fanconi Anemia Patients Using Autofluorescence Imaging and Cytology-On-A Chip Assay.

Abram TJ, Pickering CR, Lang AK, Bass NE, Raja R, Meena C, Alousi AM, Myers JN, McDevitt JT, Gillenwater AM, Vigneswaran N.

Transl Oncol. 2018 Apr;11(2):477-486. doi: 10.1016/j.tranon.2018.01.014. Epub 2018 Feb 24.


Innovative Programmable Bio-Nano-Chip Digitizes Biology Using Sensors That Learn Bridging Biomarker Discovery and Clinical Implementation.

Christodoulides NJ, McRae MP, Abram TJ, Simmons GW, McDevitt JT.

Front Public Health. 2017 May 22;5:110. doi: 10.3389/fpubh.2017.00110. eCollection 2017. Review.


'Cytology-on-a-chip' based sensors for monitoring of potentially malignant oral lesions.

Abram TJ, Floriano PN, Christodoulides N, James R, Kerr AR, Thornhill MH, Redding SW, Vigneswaran N, Speight PM, Vick J, Murdoch C, Freeman C, Hegarty AM, D'Apice K, Phelan JA, Corby PM, Khouly I, Bouquot J, Demian NM, Weinstock YE, Rowan S, Yeh CK, McGuff HS, Miller FR, Gaur S, Karthikeyan K, Taylor L, Le C, Nguyen M, Talavera H, Raja R, Wong J, McDevitt JT.

Oral Oncol. 2016 Sep;60:103-11. doi: 10.1016/j.oraloncology.2016.07.002. Epub 2016 Jul 20.


Programmable Bio-nanochip Platform: A Point-of-Care Biosensor System with the Capacity To Learn.

McRae MP, Simmons G, Wong J, McDevitt JT.

Acc Chem Res. 2016 Jul 19;49(7):1359-68. doi: 10.1021/acs.accounts.6b00112. Epub 2016 Jul 6.


Challenges and opportunities for translating medical microdevices: insights from the programmable bio-nano-chip.

McRae MP, Simmons G, McDevitt JT.

Bioanalysis. 2016 May;8(9):905-19. doi: 10.4155/bio-2015-0023. Epub 2016 Apr 13.


Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group.

King K, Grazette LP, Paltoo DN, McDevitt JT, Sia SK, Barrett PM, Apple FS, Gurbel PA, Weissleder R, Leeds H, Iturriaga EJ, Rao A, Adhikari B, Desvigne-Nickens P, Galis ZS, Libby P.

JACC Basic Transl Sci. 2016 Jan-Feb;1(1-2):73-86.


Next Generation Programmable Bio-Nano-Chip System for On-Site Detection in Oral Fluids.

Christodoulides N, De La Garza R 2nd, Simmons GW, McRae MP, Wong J, Newton TF, Kosten TR, Haque A, McDevitt JT.

J Drug Abuse. 2015 Nov 23;1(1):1-6.


Programmable bio-nano-chip system: a flexible point-of-care platform for bioscience and clinical measurements.

McRae MP, Simmons GW, Wong J, Shadfan B, Gopalkrishnan S, Christodoulides N, McDevitt JT.

Lab Chip. 2015 Oct 21;15(20):4020-31. doi: 10.1039/c5lc00636h. Epub 2015 Aug 26.


Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials.

Speight PM, Abram TJ, Floriano PN, James R, Vick J, Thornhill MH, Murdoch C, Freeman C, Hegarty AM, D'Apice K, Kerr AR, Phelan J, Corby P, Khouly I, Vigneswaran N, Bouquot J, Demian NM, Weinstock YE, Redding SW, Rowan S, Yeh CK, McGuff HS, Miller FR, McDevitt JT.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Oct;120(4):474-82.e2. doi: 10.1016/j.oooo.2015.05.023. Epub 2015 Jun 17.


Enhancement of performance in porous bead-based microchip sensors: Effects of chip geometry on bio-agent capture.

Kulla E, Chou J, Simmons G, Wong J, McRae MP, Patel R, Floriano PN, Christodoulides N, Leach RJ, Thompson IM, McDevitt JT.

RSC Adv. 2015;5(60):48194-48206.


Application of programmable bio-nano-chip system for the quantitative detection of drugs of abuse in oral fluids.

Christodoulides N, De La Garza R 2nd, Simmons GW, McRae MP, Wong J, Newton TF, Smith R, Mahoney JJ III, Hohenstein J, Gomez S, Floriano PN, Talavera H, Sloan DJ, Moody DE, Andrenyak DM, Kosten TR, Haque A, McDevitt JT.

Drug Alcohol Depend. 2015 Aug 1;153:306-13. doi: 10.1016/j.drugalcdep.2015.04.026. Epub 2015 May 22.


Programmable bio-nano-chip system: a flexible diagnostic platform that learns.

McDevitt JT, McRae MP, Simmons GW, Christodoulides N.

J Biosens Bioelectron. 2015;6(2). pii: e137. doi: 10.4172/2155-6210.1000e137. Epub 2015 May 10. No abstract available.


A multiplexable, microfluidic platform for the rapid quantitation of a biomarker panel for early ovarian cancer detection at the point-of-care.

Shadfan BH, Simmons AR, Simmons GW, Ho A, Wong J, Lu KH, Bast RC Jr, McDevitt JT.

Cancer Prev Res (Phila). 2015 Jan;8(1):37-48. doi: 10.1158/1940-6207.CAPR-14-0248. Epub 2014 Nov 11.


Utility of salivary biomarkers for demonstrating acute myocardial infarction.

Miller CS, Foley JD 3rd, Floriano PN, Christodoulides N, Ebersole JL, Campbell CL, Bailey AL, Rose BG, Kinane DF, Novak MJ, McDevitt JT, Ding X, Kryscio RJ.

J Dent Res. 2014 Jul;93(7 Suppl):72S-79S. doi: 10.1177/0022034514537522. Epub 2014 May 30.


Hot embossed polyethylene through-hole chips for bead-based microfluidic devices.

Chou J, Du N, Ou T, Floriano PN, Christodoulides N, McDevitt JT.

Biosens Bioelectron. 2013 Apr 15;42:653-60. doi: 10.1016/j.bios.2012.09.056. Epub 2012 Oct 4.


Effects of sample delivery on analyte capture in porous bead sensors.

Chou J, Li LE, Kulla E, Christodoulides N, Floriano PN, McDevitt JT.

Lab Chip. 2012 Dec 21;12(24):5249-56. doi: 10.1039/c2lc40752c.


Salivary biomarkers associated with myocardial necrosis: results from an alcohol septal ablation model.

Foley JD 3rd, Sneed JD, Steinhubl SR, Kolasa JR, Ebersole JL, Lin Y, Kryscio RJ, McDevitt JT, Campbell CL, Miller CS.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Nov;114(5):616-23. doi: 10.1016/j.oooo.2012.05.024. Epub 2012 Sep 28.


Programmable bio-nanochip technology for the diagnosis of cardiovascular disease at the point-of-care.

Christodoulides N, Pierre FN, Sanchez X, Li L, Hocquard K, Patton A, Muldoon R, Miller CS, Ebersole JL, Redding S, Yeh CK, Furmaga WB, Wampler DA, Bozkurt B, Ballantyne CM, McDevitt JT.

Methodist Debakey Cardiovasc J. 2012 Jan;8(1):6-12. Review. Erratum in: Methodist Debakey Cardiovasc J. 2012 Jul-Sep;8(3):48.


Oral fluids that detect cardiovascular disease biomarkers.

Foley JD 3rd, Sneed JD, Steinhubl SR, Kolasa J, Ebersole JL, Lin Y, Kryscio RJ, McDevitt JT, Campbell CL, Miller CS.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Aug;114(2):207-14. doi: 10.1016/j.oooo.2012.03.003.


Programmable bio-nano-chip systems for serum CA125 quantification: toward ovarian cancer diagnostics at the point-of-care.

Raamanathan A, Simmons GW, Christodoulides N, Floriano PN, Furmaga WB, Redding SW, Lu KH, Bast RC Jr, McDevitt JT.

Cancer Prev Res (Phila). 2012 May;5(5):706-16. doi: 10.1158/1940-6207.CAPR-11-0508. Epub 2012 Apr 9.


Modeling analyte transport and capture in porous bead sensors.

Chou J, Lennart A, Wong J, Ali MF, Floriano PN, Christodoulides N, Camp J, McDevitt JT.

Anal Chem. 2012 Mar 6;84(5):2569-75. doi: 10.1021/ac2022822. Epub 2012 Feb 9.


Perspective on diagnostics for global health.

Fu E, Yager P, Floriano PN, Christodoulides N, McDevitt JT.

IEEE Pulse. 2011 Nov;2(6):40-50. doi: 10.1109/MPUL.2011.942766. No abstract available.


Translational and clinical applications of salivary diagnostics.

Giannobile WV, McDevitt JT, Niedbala RS, Malamud D.

Adv Dent Res. 2011 Oct;23(4):375-80. doi: 10.1177/0022034511420434.


A disposable bio-nano-chip using agarose beads for high performance immunoassays.

Du N, Chou J, Kulla E, Floriano PN, Christodoulides N, McDevitt JT.

Biosens Bioelectron. 2011 Oct 15;28(1):251-6. doi: 10.1016/j.bios.2011.07.027. Epub 2011 Jul 23.


Location of biomarkers and reagents within agarose beads of a programmable bio-nano-chip.

Jokerst JV, Chou J, Camp JP, Wong J, Lennart A, Pollard AA, Floriano PN, Christodoulides N, Simmons GW, Zhou Y, Ali MF, McDevitt JT.

Small. 2011 Mar 7;7(5):613-24. doi: 10.1002/smll.201002089. Epub 2011 Feb 2.


Current developments in salivary diagnostics.

Miller CS, Foley JD, Bailey AL, Campell CL, Humphries RL, Christodoulides N, Floriano PN, Simmons G, Bhagwandin B, Jacobson JW, Redding SW, Ebersole JL, McDevitt JT.

Biomark Med. 2010 Feb;4(1):171-89. Review.


Nano-bio-chip sensor platform for examination of oral exfoliative cytology.

Weigum SE, Floriano PN, Redding SW, Yeh CK, Westbrook SD, McGuff HS, Lin A, Miller FR, Villarreal F, Rowan SD, Vigneswaran N, Williams MD, McDevitt JT.

Cancer Prev Res (Phila). 2010 Apr;3(4):518-28. doi: 10.1158/1940-6207.CAPR-09-0139. Epub 2010 Mar 23.


Programmable nano-bio-chip sensors: analytical meets clinical.

Jokerst JV, Jacobson JW, Bhagwandin BD, Floriano PN, Christodoulides N, McDevitt JT.

Anal Chem. 2010 Mar 1;82(5):1571-9. doi: 10.1021/ac901743u.


Programmable nano-bio-chips: multifunctional clinical tools for use at the point-of-care.

Jokerst JV, McDevitt JT.

Nanomedicine (Lond). 2010 Jan;5(1):143-55. doi: 10.2217/nnm.09.94. Erratum in: Nanomedicine (Lond). 2013 Jan;8(1):160.


Nano-bio-chips for high performance multiplexed protein detection: determinations of cancer biomarkers in serum and saliva using quantum dot bioconjugate labels.

Jokerst JV, Raamanathan A, Christodoulides N, Floriano PN, Pollard AA, Simmons GW, Wong J, Gage C, Furmaga WB, Redding SW, McDevitt JT.

Biosens Bioelectron. 2009 Aug 15;24(12):3622-9. doi: 10.1016/j.bios.2009.05.026. Epub 2009 May 27.


Use of saliva-based nano-biochip tests for acute myocardial infarction at the point of care: a feasibility study.

Floriano PN, Christodoulides N, Miller CS, Ebersole JL, Spertus J, Rose BG, Kinane DF, Novak MJ, Steinhubl S, Acosta S, Mohanty S, Dharshan P, Yeh CK, Redding S, Furmaga W, McDevitt JT.

Clin Chem. 2009 Aug;55(8):1530-8. doi: 10.1373/clinchem.2008.117713. Epub 2009 Jun 25.


Integration of semiconductor quantum dots into nano-bio-chip systems for enumeration of CD4+ T cell counts at the point-of-need.

Jokerst JV, Floriano PN, Christodoulides N, Simmons GW, McDevitt JT.

Lab Chip. 2008 Dec;8(12):2079-90. doi: 10.1039/b817116e. Epub 2008 Nov 5.


A microchip-based assay for interleukin-6.

Christodoulides N, Dharshan P, Wong J, Floriano PN, Neikirk D, McDevitt JT.

Methods Mol Biol. 2007;385:131-44.


Microchip-based enumeration of human white blood cells.

Floriano PN, Acosta S, Christodoulides N, Weigum S, McDevitt JT.

Methods Mol Biol. 2007;385:53-64.


Immobilization of a hexaphyrin( derivative onto a tentagel-amino resin and its use in uranyl cation detection.

Melfi PJ, Camiolo S, Lee JT, Ali MF, McDevitt JT, Lynch VM, Sessler JL.

Dalton Trans. 2008 Mar 28;(12):1538-40. doi: 10.1039/b718627d. Epub 2008 Feb 7.


Boronic acid based peptidic receptors for pattern-based saccharide sensing in neutral aqueous media, an application in real-life samples.

Edwards NY, Sager TW, McDevitt JT, Anslyn EV.

J Am Chem Soc. 2007 Nov 7;129(44):13575-83. Epub 2007 Oct 10.


The discriminatory power of differential receptor arrays is improved by prescreening-a demonstration in the analysis of tachykinins and similar peptides.

Wright AT, Edwards NY, Anslyn EV, McDevitt JT.

Angew Chem Int Ed Engl. 2007;46(43):8212-5. No abstract available.


Cell-based sensor for analysis of EGFR biomarker expression in oral cancer.

Weigum SE, Floriano PN, Christodoulides N, McDevitt JT.

Lab Chip. 2007 Aug;7(8):995-1003. Epub 2007 Jul 11.


Lab-on-a-chip methods for point-of-care measurements of salivary biomarkers of periodontitis.

Christodoulides N, Floriano PN, Miller CS, Ebersole JL, Mohanty S, Dharshan P, Griffin M, Lennart A, Ballard KL, King CP Jr, Langub MC, Kryscio RJ, Thomas MV, McDevitt JT.

Ann N Y Acad Sci. 2007 Mar;1098:411-28.


A Continuous-Flow Polymerase Chain Reaction Microchip With Regional Velocity Control.

Li S, Fozdar DY, Ali MF, Li H, Shao D, Vykoukal DM, Vykoukal J, Floriano PN, Olsen M, McDevitt JT, Gascoyne PR, Chen S.

J Microelectromech Syst. 2006 Feb 1;15(1):223-236.


A differential array of metalated synthetic receptors for the analysis of tripeptide mixtures.

Wright AT, Anslyn EV, McDevitt JT.

J Am Chem Soc. 2005 Dec 14;127(49):17405-11.


Toward the development of a lab-on-a-chip dual-function leukocyte and C-reactive protein analysis method for the assessment of inflammation and cardiac risk.

Christodoulides N, Floriano PN, Acosta SA, Ballard KL, Weigum SE, Mohanty S, Dharshan P, Romanovicz D, McDevitt JT.

Clin Chem. 2005 Dec;51(12):2391-5. No abstract available.


Disposable polydimethylsiloxane/silicon hybrid chips for protein detection.

Li S, Floriano PN, Christodoulides N, Fozdar DY, Shao D, Ali MF, Dharshan P, Mohanty S, Neikirk D, McDevitt JT, Chen S.

Biosens Bioelectron. 2005 Oct 15;21(4):574-80. Epub 2005 Jan 22.


Differential receptors create patterns that distinguish various proteins.

Wright AT, Griffin MJ, Zhong Z, McCleskey SC, Anslyn EV, McDevitt JT.

Angew Chem Int Ed Engl. 2005 Oct 7;44(39):6375-8. No abstract available.


A microbead array chemical sensor using capillary-based sample introduction: toward the development of an "electronic tongue".

Sohn YS, Goodey A, Anslyn EV, McDevitt JT, Shear JB, Neikirk DP.

Biosens Bioelectron. 2005 Aug 15;21(2):303-12. Epub 2004 Dec 2.


A microchip CD4 counting method for HIV monitoring in resource-poor settings.

Rodriguez WR, Christodoulides N, Floriano PN, Graham S, Mohanty S, Dixon M, Hsiang M, Peter T, Zavahir S, Thior I, Romanovicz D, Bernard B, Goodey AP, Walker BD, McDevitt JT.

PLoS Med. 2005 Jul;2(7):e182. Epub 2005 Jul 19.


Membrane-based on-line optical analysis system for rapid detection of bacteria and spores.

Floriano PN, Christodoulides N, Romanovicz D, Bernard B, Simmons GW, Cavell M, McDevitt JT.

Biosens Bioelectron. 2005 Apr 15;20(10):2079-88.


Application of microchip assay system for the measurement of C-reactive protein in human saliva.

Christodoulides N, Mohanty S, Miller CS, Langub MC, Floriano PN, Dharshan P, Ali MF, Bernard B, Romanovicz D, Anslyn E, Fox PC, McDevitt JT.

Lab Chip. 2005 Mar;5(3):261-9. Epub 2005 Jan 13.


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