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Items: 1 to 50 of 268

1.

The role of interferon alpha in initiation of type I diabetes in the NOD mouse.

Li Q, McDevitt HO.

Clin Immunol. 2011 Jul;140(1):3-7. doi: 10.1016/j.clim.2011.04.010. Epub 2011 Apr 22.

PMID:
21592863
2.

Autoimmune diabetes mellitus--much progress, but many challenges.

McDevitt HO, Unanue ER.

Adv Immunol. 2008;100:1-12. doi: 10.1016/S0065-2776(08)00801-8. Review. No abstract available.

PMID:
19111161
3.

Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice.

Li Q, Xu B, Michie SA, Rubins KH, Schreriber RD, McDevitt HO.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12439-44. doi: 10.1073/pnas.0806439105. Epub 2008 Aug 20.

4.

Genomic expression profiling of TNF-alpha-treated BDC2.5 diabetogenic CD4+ T cells.

Lee LF, Lih CJ, Huang CJ, Cao T, Cohen SN, McDevitt HO.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10107-12. doi: 10.1073/pnas.0803336105. Epub 2008 Jul 15.

5.

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.

Chaparro RJ, Konigshofer Y, Beilhack GF, Shizuru JA, McDevitt HO, Chien YH.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12475-80. Epub 2006 Aug 8. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15273.

6.

DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.

Durinovic-Belló I, Rosinger S, Olson JA, Congia M, Ahmad RC, Rickert M, Hampl J, Kalbacher H, Drijfhout JW, Mellins ED, Al Dahouk S, Kamradt T, Maeurer MJ, Nhan C, Roep BO, Boehm BO, Polychronakos C, Nepom GT, Karges W, McDevitt HO, Sønderstrup G.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11683-8. Epub 2006 Jul 25.

7.
8.

The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation.

Lee LF, Xu B, Michie SA, Beilhack GF, Warganich T, Turley S, McDevitt HO.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15995-6000. Epub 2005 Oct 24.

9.

Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene.

Ranheim EA, Tarbell KV, Krogsgaard M, Mallet-Designe V, Teyton L, McDevitt HO, Weissman IL.

Autoimmunity. 2004 Dec;37(8):555-67.

PMID:
15763918
10.

Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells.

Kim SK, Tarbell KV, Sanna M, Vadeboncoeur M, Warganich T, Lee M, Davis M, McDevitt HO.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14204-9. Epub 2004 Sep 20.

11.

Genetic control of the antibody responses: relationship between immune response and histocompatibility (H-2) type. 1969.

McDevitt HO, Chinitz A.

J Immunol. 2004 Aug 1;173(3):1500-1. No abstract available.

12.

Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice.

Wu AJ, Hua H, Munson SH, McDevitt HO.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12287-92. Epub 2002 Sep 9.

13.

A critical role for lymphotoxin-beta receptor in the development of diabetes in nonobese diabetic mice.

Ettinger R, Munson SH, Chao CC, Vadeboncoeur M, Toma J, McDevitt HO.

J Exp Med. 2001 Jun 4;193(11):1333-40.

14.

DR, DQ, and you: MHC alleles and autoimmunity.

Sønderstrup G, McDevitt HO.

J Clin Invest. 2001 Apr;107(7):795-6. Review. No abstract available.

15.

Discovering the role of the major histocompatibility complex in the immune response.

McDevitt HO.

Annu Rev Immunol. 2000;18:1-17. Review.

PMID:
10837050
16.

HLA class II transgenic mice: models of the human CD4+ T-cell immune response.

Sønderstrup G, Cope AP, Patel S, Congia M, Hain N, Hall FC, Parry SL, Fugger LH, Michie S, McDevitt HO.

Immunol Rev. 1999 Dec;172:335-43. Review.

PMID:
10631958
17.

The role of MHC class II molecules in susceptibility to type I diabetes: identification of peptide epitopes and characterization of the T cell repertoire.

Chao CC, Sytwu HK, Chen EL, Toma J, McDevitt HO.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9299-304. Erratum in: Proc Natl Acad Sci U S A 1999 Oct 26;96(22):12970.

18.

Redirecting Th1 and Th2 responses in autoimmune disease.

Pearson CI, McDevitt HO.

Curr Top Microbiol Immunol. 1999;238:79-122. Review. No abstract available.

PMID:
10087651
19.

Autoimmunity

McDevitt HO, Wakeland EK.

Curr Opin Immunol. 1998 Dec;10(6):647-8. No abstract available.

PMID:
9914230
20.

The role of MHC class II molecules in susceptibility and resistance to autoimmunity.

McDevitt HO.

Curr Opin Immunol. 1998 Dec;10(6):677-81. Review.

PMID:
9914229
21.

A small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11.

Pearson CI, Gautam AM, Rulifson IC, Liblau RS, McDevitt HO.

Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):197-202.

22.

Prevention of diabetes in NOD mice by a mutated I-Ab transgene.

Singer SM, Tisch R, Yang XD, Sytwu HK, Liblau R, McDevitt HO.

Diabetes. 1998 Oct;47(10):1570-7.

PMID:
9753294
23.

Effects of tumor necrosis factor and lymphotoxin on peripheral lymphoid tissue development.

Ettinger R, Mebius R, Browning JL, Michie SA, van Tuijl S, Kraal G, van Ewijk W, McDevitt HO.

Int Immunol. 1998 Jun;10(6):727-41.

PMID:
9678753
24.

Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice.

Tisch R, Liblau RS, Yang XD, Liblau P, McDevitt HO.

Diabetes. 1998 Jun;47(6):894-9.

PMID:
9604865
25.

Systemic antigen in the treatment of T-cell-mediated autoimmune diseases.

Liblau R, Tisch R, Bercovici N, McDevitt HO.

Immunol Today. 1997 Dec;18(12):599-604. Review.

PMID:
9425739
26.

Reduction in diabetes incidence in an I-Ag7 transgenic nonobese diabetic mouse line.

Wherrett DK, Singer SM, McDevitt HO.

Diabetes. 1997 Dec;46(12):1970-4.

PMID:
9392482
27.

CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice.

Balasa B, Krahl T, Patstone G, Lee J, Tisch R, McDevitt HO, Sarvetnick N.

J Immunol. 1997 Nov 1;159(9):4620-7.

PMID:
9379064
28.
29.
30.

Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling.

Cope AP, Liblau RS, Yang XD, Congia M, Laudanna C, Schreiber RD, Probert L, Kollias G, McDevitt HO.

J Exp Med. 1997 May 5;185(9):1573-84.

31.

Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation.

Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3195-9.

33.
34.

Association of DPB1 genes with systemic lupus erythematosus.

Fronek Z, Cheung MM, McDevitt HO.

J Rheumatol. 1997 Jan;24(1):232-4. No abstract available.

PMID:
9002053
35.

Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-beta receptor-IgG1 fusion protein.

Ettinger R, Browning JL, Michie SA, van Ewijk W, McDevitt HO.

Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13102-7.

36.

No linkage or association of telomeric and centromeric T-cell receptor beta-chain markers with susceptibility to type 1 insulin-dependent diabetes in HLA-DR4 multiplex families.

McDermott MF, Schmidt-Wolf G, Sinha AA, Koo M, Porter MA, Briant L, Cambon-Thomsen A, Maclaren NK, Fiske D, Bertera S, Trucco M, Amos CI, McDevitt HO, Kastner DL.

Eur J Immunogenet. 1996 Oct;23(5):361-70.

PMID:
8909943
37.

CD8(+) T cell-mediated spontaneous diabetes in neonatal mice.

Morgan DJ, Liblau R, Scott B, Fleck S, McDevitt HO, Sarvetnick N, Lo D, Sherman LA.

J Immunol. 1996 Aug 1;157(3):978-83.

PMID:
8757600
38.
39.

The role of cell adhesion molecules in the development of IDDM: implications for pathogenesis and therapy.

Yang XD, Michie SA, Mebius RE, Tisch R, Weissman I, McDevitt HO.

Diabetes. 1996 Jun;45(6):705-10. Review.

PMID:
8635641
40.

Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis.

Liblau RS, Tisch R, Shokat K, Yang X, Dumont N, Goodnow CC, McDevitt HO.

Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):3031-6.

41.

High copy number I-Ab transgenes induce production of IgE through an interluekin 4-dependent mechanism.

Singer SM, Umetsu DT, McDevitt HO.

Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2947-52.

43.

Albert Hewett Coons - June 28, 1912-September 30, 1978.

McDevitt HO.

Biogr Mem Natl Acad Sci. 1996;69:27-36. No abstract available.

PMID:
11616256
44.

Autoimmune diabetes and its antigenic triggers.

McDevitt HO.

Hosp Pract (1995). 1995 Jul 15;30(7):55-62. Review.

PMID:
7601898
45.

Binding of an invariant-chain peptide, CLIP, to I-A major histocompatibility complex class II molecules.

Gautam AM, Pearson C, Quinn V, McDevitt HO, Milburn PJ.

Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):335-9.

46.

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

Liblau RS, Singer SM, McDevitt HO.

Immunol Today. 1995 Jan;16(1):34-8. Review.

PMID:
7880387
47.

Selective targets for immunotherapy in autoimmune disease.

Yang XD, Tisch R, McDevitt HO.

Chem Immunol. 1995;60:20-31. Review. No abstract available.

PMID:
7857527
48.

A predominant role of integrin alpha 4 in the spontaneous development of autoimmune diabetes in nonobese diabetic mice.

Yang XD, Michie SA, Tisch R, Karin N, Steinman L, McDevitt HO.

Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12604-8.

49.

Administering glutamic acid decarboxylase to NOD mice prevents diabetes.

Tisch R, Yang XD, Liblau RS, McDevitt HO.

J Autoimmun. 1994 Dec;7(6):845-50.

PMID:
7888040
50.

High-dose soluble antigen: peripheral T-cell proliferation or apoptosis.

Liblau RS, Pearson CI, Shokat K, Tisch R, Yang XD, McDevitt HO.

Immunol Rev. 1994 Dec;142:193-208. Review. No abstract available.

PMID:
7698794

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