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Items: 1 to 50 of 85

1.

The structure and activity of the glutathione reductase from Streptococcus pneumoniae.

Sikanyika M, Aragão D, McDevitt CA, Maher MJ.

Acta Crystallogr F Struct Biol Commun. 2019 Jan 1;75(Pt 1):54-61. doi: 10.1107/S2053230X18016527. Epub 2019 Jan 1.

PMID:
30605126
2.

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.

Bohlmann L, De Oliveira DMP, El-Deeb IM, Brazel EB, Harbison-Price N, Ong CY, Rivera-Hernandez T, Ferguson SA, Cork AJ, Phan MD, Soderholm AT, Davies MR, Nimmo GR, Dougan G, Schembri MA, Cook GM, McEwan AG, von Itzstein M, McDevitt CA, Walker MJ.

MBio. 2018 Dec 11;9(6). pii: e02391-18. doi: 10.1128/mBio.02391-18.

3.

A Liposomal Platform for Sensing of Extracellular Analytes Near Cells.

Zhang X, Heng S, Pei J, Morey JR, McDevitt CA, Abell AD.

Biosensors (Basel). 2018 Nov 26;8(4). pii: E117. doi: 10.3390/bios8040117.

4.

Synergy between Nutritional Immunity and Independent Host Defenses Contributes to the Importance of the MntABC Manganese Transporter during Staphylococcus aureus Infection.

Radin JN, Zhu J, Brazel EB, McDevitt CA, Kehl-Fie TE.

Infect Immun. 2018 Dec 19;87(1). pii: e00642-18. doi: 10.1128/IAI.00642-18. Print 2019 Jan.

PMID:
30348827
5.

Antimicrobial Susceptibility of Escherichia coli and Salmonella spp. Isolates From Healthy Pigs in Australia: Results of a Pilot National Survey.

Kidsley AK, Abraham S, Bell JM, O'Dea M, Laird TJ, Jordan D, Mitchell P, McDevitt CA, Trott DJ.

Front Microbiol. 2018 Jul 9;9:1207. doi: 10.3389/fmicb.2018.01207. eCollection 2018.

6.

Arachidonic Acid Stress Impacts Pneumococcal Fatty Acid Homeostasis.

Eijkelkamp BA, Begg SL, Pederick VG, Trapetti C, Gregory MK, Whittall JJ, Paton JC, McDevitt CA.

Front Microbiol. 2018 May 11;9:813. doi: 10.3389/fmicb.2018.00813. eCollection 2018.

7.

Structural characterisation of the HT3 motif of the polyhistidine triad protein D from Streptococcus pneumoniae.

Luo Z, Pederick VG, Paton JC, McDevitt CA, Kobe B.

FEBS Lett. 2018 Jul;592(13):2341-2350. doi: 10.1002/1873-3468.13122. Epub 2018 Jun 14.

PMID:
29856892
8.

Biotin-mediated growth and gene expression in Staphylococcus aureus is highly responsive to environmental biotin.

Satiaputra J, Eijkelkamp BA, McDevitt CA, Shearwin KE, Booker GW, Polyak SW.

Appl Microbiol Biotechnol. 2018 Apr;102(8):3793-3803. doi: 10.1007/s00253-018-8866-z. Epub 2018 Mar 5.

PMID:
29508030
9.

The Metallophore Staphylopine Enables Staphylococcus aureus To Compete with the Host for Zinc and Overcome Nutritional Immunity.

Grim KP, San Francisco B, Radin JN, Brazel EB, Kelliher JL, Párraga Solórzano PK, Kim PC, McDevitt CA, Kehl-Fie TE.

MBio. 2017 Oct 31;8(5). pii: e01281-17. doi: 10.1128/mBio.01281-17.

10.

Genome-Wide Mutagenesis of Dengue Virus Reveals Plasticity of the NS1 Protein and Enables Generation of Infectious Tagged Reporter Viruses.

Eyre NS, Johnson SM, Eltahla AA, Aloi M, Aloia AL, McDevitt CA, Bull RA, Beard MR.

J Virol. 2017 Nov 14;91(23). pii: e01455-17. doi: 10.1128/JVI.01455-17. Print 2017 Dec 1.

11.

Zinc stress induces copper depletion in Acinetobacter baumannii.

Hassan KA, Pederick VG, Elbourne LD, Paulsen IT, Paton JC, McDevitt CA, Eijkelkamp BA.

BMC Microbiol. 2017 Mar 11;17(1):59. doi: 10.1186/s12866-017-0965-y.

12.

The zinc efflux activator SczA protects Streptococcus pneumoniae serotype 2 D39 from intracellular zinc toxicity.

Martin JE, Edmonds KA, Bruce KE, Campanello GC, Eijkelkamp BA, Brazel EB, McDevitt CA, Winkler ME, Giedroc DP.

Mol Microbiol. 2017 May;104(4):636-651. doi: 10.1111/mmi.13654. Epub 2017 Mar 21.

13.

Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence.

Trappetti C, McAllister LJ, Chen A, Wang H, Paton AW, Oggioni MR, McDevitt CA, Paton JC.

MBio. 2017 Jan 24;8(1). pii: e02269-16. doi: 10.1128/mBio.02269-16.

14.

Microstructured Optical Fiber-based Biosensors: Reversible and Nanoliter-Scale Measurement of Zinc Ions.

Heng S, McDevitt CA, Kostecki R, Morey JR, Eijkelkamp BA, Ebendorff-Heidepriem H, Monro TM, Abell AD.

ACS Appl Mater Interfaces. 2016 May 25;8(20):12727-32. doi: 10.1021/acsami.6b03565. Epub 2016 May 13.

PMID:
27152578
15.

Heterogeneous nucleation is required for crystallization of the ZnuA domain of pneumococcal AdcA.

Luo Z, Morey JR, McDevitt CA, Kobe B.

Acta Crystallogr F Struct Biol Commun. 2015 Dec;71(Pt 12):1459-64. doi: 10.1107/S2053230X15021330. Epub 2015 Nov 18.

16.

The First Histidine Triad Motif of PhtD Is Critical for Zinc Homeostasis in Streptococcus pneumoniae.

Eijkelkamp BA, Pederick VG, Plumptre CD, Harvey RM, Hughes CE, Paton JC, McDevitt CA.

Infect Immun. 2015 Nov 16;84(2):407-15. doi: 10.1128/IAI.01082-15. Print 2016 Feb.

17.

Characterizing the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopy.

Deplazes E, Begg SL, van Wonderen JH, Campbell R, Kobe B, Paton JC, MacMillan F, McDevitt CA, O'Mara ML.

Biophys Chem. 2015 Dec;207:51-60. doi: 10.1016/j.bpc.2015.08.004. Epub 2015 Sep 3.

PMID:
26379256
18.

ZnuA and zinc homeostasis in Pseudomonas aeruginosa.

Pederick VG, Eijkelkamp BA, Begg SL, Ween MP, McAllister LJ, Paton JC, McDevitt CA.

Sci Rep. 2015 Aug 20;5:13139. doi: 10.1038/srep13139.

19.

Host-imposed manganese starvation of invading pathogens: two routes to the same destination.

Morey JR, McDevitt CA, Kehl-Fie TE.

Biometals. 2015 Jun;28(3):509-19. doi: 10.1007/s10534-015-9850-z. Epub 2015 Apr 3. Review.

20.

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach.

Bajaj M, Mamidyala SK, Zuegg J, Begg SL, Ween MP, Luo Z, Huang JX, McEwan AG, Kobe B, Paton JC, McDevitt CA, Cooper MA.

ACS Chem Biol. 2015 Jun 19;10(6):1511-20. doi: 10.1021/cb501032x. Epub 2015 Mar 30.

PMID:
25786639
21.

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae.

Begg SL, Eijkelkamp BA, Luo Z, Couñago RM, Morey JR, Maher MJ, Ong CL, McEwan AG, Kobe B, O'Mara ML, Paton JC, McDevitt CA.

Nat Commun. 2015 Mar 3;6:6418. doi: 10.1038/ncomms7418.

22.

Manganese uptake and streptococcal virulence.

Eijkelkamp BA, McDevitt CA, Kitten T.

Biometals. 2015 Jun;28(3):491-508. doi: 10.1007/s10534-015-9826-z. Epub 2015 Feb 5. Review.

23.

Acquisition and role of molybdate in Pseudomonas aeruginosa.

Pederick VG, Eijkelkamp BA, Ween MP, Begg SL, Paton JC, McDevitt CA.

Appl Environ Microbiol. 2014 Nov;80(21):6843-52. doi: 10.1128/AEM.02465-14. Epub 2014 Aug 29.

24.

Overlapping functionality of the Pht proteins in zinc homeostasis of Streptococcus pneumoniae.

Plumptre CD, Hughes CE, Harvey RM, Eijkelkamp BA, McDevitt CA, Paton JC.

Infect Immun. 2014 Oct;82(10):4315-24. doi: 10.1128/IAI.02155-14. Epub 2014 Jul 28.

25.

The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis.

van Wonderen JH, McMahon RM, O'Mara ML, McDevitt CA, Thomson AJ, Kerr ID, MacMillan F, Callaghan R.

FEBS J. 2014 May;281(9):2190-2201. doi: 10.1111/febs.12773. Epub 2014 Apr 1.

26.

Extracellular zinc competitively inhibits manganese uptake and compromises oxidative stress management in Streptococcus pneumoniae.

Eijkelkamp BA, Morey JR, Ween MP, Ong CL, McEwan AG, Paton JC, McDevitt CA.

PLoS One. 2014 Feb 18;9(2):e89427. doi: 10.1371/journal.pone.0089427. eCollection 2014.

27.

AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae.

Plumptre CD, Eijkelkamp BA, Morey JR, Behr F, Couñago RM, Ogunniyi AD, Kobe B, O'Mara ML, Paton JC, McDevitt CA.

Mol Microbiol. 2014 Feb;91(4):834-51. doi: 10.1111/mmi.12504. Epub 2014 Jan 16.

28.

Imperfect coordination chemistry facilitates metal ion release in the Psa permease.

Couñago RM, Ween MP, Begg SL, Bajaj M, Zuegg J, O'Mara ML, Cooper MA, McEwan AG, Paton JC, Kobe B, McDevitt CA.

Nat Chem Biol. 2014 Jan;10(1):35-41. doi: 10.1038/nchembio.1382. Epub 2013 Nov 10.

PMID:
24212134
29.

Improving the stability and function of purified ABCB1 and ABCA4: the influence of membrane lipids.

Pollock NL, McDevitt CA, Collins R, Niesten PH, Prince S, Kerr ID, Ford RC, Callaghan R.

Biochim Biophys Acta. 2014 Jan;1838(1 Pt B):134-47. doi: 10.1016/j.bbamem.2013.09.001. Epub 2013 Sep 12.

30.

Microstructured optical fibers and live cells: a water-soluble, photochromic zinc sensor.

Heng S, McDevitt CA, Stubing DB, Whittall JJ, Thompson JG, Engler TK, Abell AD, Monro TM.

Biomacromolecules. 2013 Oct 14;14(10):3376-9. doi: 10.1021/bm401040v. Epub 2013 Sep 13.

PMID:
23980997
31.

Degrees of chloroquine resistance in Plasmodium - is the redox system involved?

Lehane AM, McDevitt CA, Kirk K, Fidock DA.

Int J Parasitol Drugs Drug Resist. 2012 Dec 1;2:47-57.

32.

Prokaryotic substrate-binding proteins as targets for antimicrobial therapies.

Couñago RM, McDevitt CA, Ween MP, Kobe B.

Curr Drug Targets. 2012 Oct;13(11):1400-10.

PMID:
22664093
33.

The role of ATP-binding cassette transporters in bacterial pathogenicity.

Lewis VG, Ween MP, McDevitt CA.

Protoplasma. 2012 Oct;249(4):919-42. Epub 2012 Jan 13. Review.

PMID:
22246051
34.

A molecular mechanism for bacterial susceptibility to zinc.

McDevitt CA, Ogunniyi AD, Valkov E, Lawrence MC, Kobe B, McEwan AG, Paton JC.

PLoS Pathog. 2011 Nov;7(11):e1002357. doi: 10.1371/journal.ppat.1002357. Epub 2011 Nov 3.

35.

Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae.

Ogunniyi AD, Mahdi LK, Jennings MP, McEwan AG, McDevitt CA, Van der Hoek MB, Bagley CJ, Hoffmann P, Gould KA, Paton JC.

J Bacteriol. 2010 Sep;192(17):4489-97. doi: 10.1128/JB.00064-10. Epub 2010 Jul 2.

36.

Generating inhibitors of P-glycoprotein: where to, now?

Crowley E, McDevitt CA, Callaghan R.

Methods Mol Biol. 2010;596:405-32. doi: 10.1007/978-1-60761-416-6_18.

PMID:
19949934
37.

Purification and structural analyses of ABCG2.

McDevitt CA, Collins R, Kerr ID, Callaghan R.

Adv Drug Deliv Rev. 2009 Jan 31;61(1):57-65. doi: 10.1016/j.addr.2008.07.004. Epub 2008 Dec 13. Review.

PMID:
19124053
38.

Structural insights into P-glycoprotein (ABCB1) by small angle X-ray scattering and electron crystallography.

McDevitt CA, Shintre CA, Grossmann JG, Pollock NL, Prince SM, Callaghan R, Ford RC.

FEBS Lett. 2008 Aug 20;582(19):2950-6. doi: 10.1016/j.febslet.2008.07.022. Epub 2008 Jul 25.

39.

Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2?

McDevitt CA, Crowley E, Hobbs G, Starr KJ, Kerr ID, Callaghan R.

FEBS J. 2008 Sep;275(17):4354-62. doi: 10.1111/j.1742-4658.2008.06578.x. Epub 2008 Jul 24.

40.
41.

How can we best use structural information on P-glycoprotein to design inhibitors?

McDevitt CA, Callaghan R.

Pharmacol Ther. 2007 Feb;113(2):429-41. Epub 2006 Nov 18. Review.

PMID:
17208306
42.

Purification and 3D structural analysis of oligomeric human multidrug transporter ABCG2.

McDevitt CA, Collins RF, Conway M, Modok S, Storm J, Kerr ID, Ford RC, Callaghan R.

Structure. 2006 Nov;14(11):1623-32.

43.

The TatA component of the twin-arginine protein transport system forms channel complexes of variable diameter.

Gohlke U, Pullan L, McDevitt CA, Porcelli I, de Leeuw E, Palmer T, Saibil HR, Berks BC.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10482-6. Epub 2005 Jul 18.

45.

Characterisation of Tat protein transport complexes carrying inactivating mutations.

McDevitt CA, Hicks MG, Palmer T, Berks BC.

Biochem Biophys Res Commun. 2005 Apr 8;329(2):693-8.

PMID:
15737641
46.

Spatial organization of types I and II collagen in the canine meniscus.

Kambic HE, McDevitt CA.

J Orthop Res. 2005 Jan;23(1):142-9.

47.

Transforming growth factor-beta1 in a sterilized tissue derived from the pig small intestine submucosa.

McDevitt CA, Wildey GM, Cutrone RM.

J Biomed Mater Res A. 2003 Nov 1;67(2):637-40.

PMID:
14566807
48.

Characterization of the redox centers in dimethyl sulfide dehydrogenase from Rhodovulum sulfidophilum.

McDevitt CA, Hanson GR, Noble CJ, Cheesman MR, McEwan AG.

Biochemistry. 2002 Dec 24;41(51):15234-44.

PMID:
12484761
50.

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