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Items: 1 to 50 of 86

1.

Discrepancies in the Tumor Microenvironment of Spontaneous and Orthotopic Murine Models of Pancreatic Cancer Uncover a New Immunostimulatory Phenotype for B Cells.

Spear S, Candido JB, McDermott JR, Ghirelli C, Maniati E, Beers SA, Balkwill FR, Kocher HM, Capasso M.

Front Immunol. 2019 Mar 27;10:542. doi: 10.3389/fimmu.2019.00542. eCollection 2019.

2.

Neoadjuvant Chemotherapy Modulates the Immune Microenvironment in Metastases of Tubo-Ovarian High-Grade Serous Carcinoma.

Böhm S, Montfort A, Pearce OM, Topping J, Chakravarty P, Everitt GL, Clear A, McDermott JR, Ennis D, Dowe T, Fitzpatrick A, Brockbank EC, Lawrence AC, Jeyarajah A, Faruqi AZ, McNeish IA, Singh N, Lockley M, Balkwill FR.

Clin Cancer Res. 2016 Jun 15;22(12):3025-36. doi: 10.1158/1078-0432.CCR-15-2657.

3.

Zinc- and bicarbonate-dependent ZIP8 transporter mediates selenite uptake.

McDermott JR, Geng X, Jiang L, Gálvez-Peralta M, Chen F, Nebert DW, Liu Z.

Oncotarget. 2016 Jun 7;7(23):35327-40. doi: 10.18632/oncotarget.9205.

4.

Formation and activation of thermogenic fat.

Wu J, Jun H, McDermott JR.

Trends Genet. 2015 May;31(5):232-8. doi: 10.1016/j.tig.2015.03.003. Epub 2015 Apr 4. Review.

5.

Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio.

Hamdi M, Yoshinaga M, Packianathan C, Qin J, Hallauer J, McDermott JR, Yang HC, Tsai KJ, Liu Z.

Toxicol Appl Pharmacol. 2012 Jul 15;262(2):185-93. doi: 10.1016/j.taap.2012.04.035. Epub 2012 May 7.

6.

Trivalent arsenicals and glucose use different translocation pathways in mammalian GLUT1.

Jiang X, McDermott JR, Ajees AA, Rosen BP, Liu Z.

Metallomics. 2010 Mar;2(3):211-9. doi: 10.1039/b920471g. Epub 2009 Dec 8.

7.

Jen1p: a high affinity selenite transporter in yeast.

McDermott JR, Rosen BP, Liu Z.

Mol Biol Cell. 2010 Nov 15;21(22):3934-41. doi: 10.1091/mbc.E10-06-0513. Epub 2010 Sep 22.

8.

Pentavalent methylated arsenicals are substrates of human AQP9.

McDermott JR, Jiang X, Beene LC, Rosen BP, Liu Z.

Biometals. 2010 Feb;23(1):119-27. doi: 10.1007/s10534-009-9273-9. Epub 2009 Oct 4.

9.

Immune control of food intake: enteroendocrine cells are regulated by CD4+ T lymphocytes during small intestinal inflammation.

McDermott JR, Leslie FC, D'Amato M, Thompson DG, Grencis RK, McLaughlin JT.

Gut. 2006 Apr;55(4):492-7. Epub 2005 Nov 18.

10.

Intraepithelial NK cell-derived IL-13 induces intestinal pathology associated with nematode infection.

McDermott JR, Humphreys NE, Forman SP, Donaldson DD, Grencis RK.

J Immunol. 2005 Sep 1;175(5):3207-13.

11.

Mast cells disrupt epithelial barrier function during enteric nematode infection.

McDermott JR, Bartram RE, Knight PA, Miller HR, Garrod DR, Grencis RK.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7761-6. Epub 2003 Jun 9.

12.

Leucocyte recruitment during enteric nematode infection.

McDermott JR, Grencis RK, Else KJ.

Immunology. 2001 Aug;103(4):505-10.

13.

Beta7 integrin-deficient mice: delayed leukocyte recruitment and attenuated protective immunity in the small intestine during enteric helminth infection.

Artis D, Humphreys NE, Potten CS, Wagner N, Müller W, McDermott JR, Grencis RK, Else KJ.

Eur J Immunol. 2000 Jun;30(6):1656-64.

14.
15.

Degradation of Alzheimer's beta-amyloid protein by human cathepsin D.

McDermott JR, Gibson AM.

Neuroreport. 1996 Sep 2;7(13):2163-6.

PMID:
8930981
16.

Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides.

Hornshaw MP, McDermott JR, Candy JM, Lakey JH.

Biochem Biophys Res Commun. 1995 Sep 25;214(3):993-9.

PMID:
7575574
17.

Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein.

Hornshaw MP, McDermott JR, Candy JM.

Biochem Biophys Res Commun. 1995 Feb 15;207(2):621-9.

PMID:
7864852
18.

Purification and characterization of tripeptidylpeptidase-II from post-mortem human brain.

Wilson C, Gibson AM, McDermott JR.

Neurochem Res. 1993 Jul;18(7):743-9.

PMID:
8396212
19.

Dipeptidylpeptidase IV initiates the degradation of neuropeptide Y in cardiac muscle membranes.

McDermott JR, Gibson AM, Boublik J, Biggins JA.

Biochem Soc Trans. 1992 Nov;20(4):351S. No abstract available.

PMID:
1362546
20.

Human brain peptidase activity with the specificity to generate the N-terminus of the Alzheimer beta-amyloid protein from its precursor.

McDermott JR, Biggins JA, Gibson AM.

Biochem Biophys Res Commun. 1992 Jun 15;185(2):746-52.

PMID:
1610365
21.

Identification of a human brain peptidase with the specificity to generate the N-terminus of A4/beta-amyloid protein from its precursor.

McDermott JR, Biggins JA, Gibson AM.

Biochem Soc Trans. 1992 May;20(2):206S. No abstract available.

PMID:
1397581
22.
23.

Human brain leucyl aminopeptidase: isolation, characterization and specificity against some neuropeptides.

Gibson AM, Biggins JA, Lauffart B, Mantle D, McDermott JR.

Neuropeptides. 1991 Jul;19(3):163-8.

PMID:
1680222
24.

Multicatalytic, high-Mr endopeptidase from postmortem human brain.

McDermott JR, Gibson AM, Oakley AE, Biggins JA.

J Neurochem. 1991 May;56(5):1509-17.

PMID:
2013752
25.

Specificity of action of human brain alanyl aminopeptidase on Leu-enkephalin and dynorphin-related peptides.

Gibson AM, McDermott JR, Lauffart B, Mantle D.

Neuropeptides. 1989 May-Jun;13(4):259-62.

PMID:
2568598
26.

Removal of Arg1 and Phe22 from CLIP (ACTH18-39) by rodent pituitary and blood peptidases.

McDermott JR, Biggins JA, Smith AI, Gibson AM, Keith AB, Edwardson JA.

Peptides. 1988 Jul-Aug;9(4):757-61.

PMID:
2852359
27.

Amino acid neurotransmitter levels in gliomas and their relationship to the incidence of epilepsy.

Bateman DE, Hardy JA, McDermott JR, Parker DS, Edwardson JA.

Neurol Res. 1988 Jun;10(2):112-4.

PMID:
2902524
28.
29.

Raised thyrotrophin-releasing hormone, pyroglutamylamino peptidase, and proline endopeptidase are present in the spinal cord of wobbler mice but not in human motor neurone disease.

Court JA, McDermott JR, Gibson AM, Marshall E, Bloxham CA, Perry RH, Edwardson JA.

J Neurochem. 1987 Oct;49(4):1084-90.

PMID:
2442304
30.

Thyrotrophin releasing hormone degradation by rat synaptosomal peptidases: production of the metabolite His-Pro.

Coggins PJ, McDermott JR, Snell CR, Gibson AM.

Neuropeptides. 1987 Aug-Sep;10(2):147-56.

PMID:
2891073
31.

Involvement of endopeptidase 24.15 in the inactivation of bradykinin by rat brain slices.

McDermott JR, Gibson AM, Turner JD.

Biochem Biophys Res Commun. 1987 Jul 15;146(1):154-8.

PMID:
2886123
32.

High affinity specific binding of the thyrotrophin releasing hormone metabolite histidylproline to rat brain membranes.

Coggins PJ, McDermott JR, Snell CR.

Neuropeptides. 1987 Jan;9(1):83-91. Erratum in: Neuropeptides 1987 May-Jun;9(4):379.

PMID:
3104816
33.

Stability of [D-Trp11]-neurotensin to rat brain peptidases.

McDermott JR, Gibson AM, Biggins JA.

Neurosci Lett. 1986 Dec 3;72(1):79-83.

PMID:
3543750
34.

Neuropeptides in gliomas: identification of somatostatin 14 in a medulloblastoma.

Bateman DE, McDermott JR, Perry RH, Dimaline R, Biggins JA, Edwardson JA.

J Neurol Neurosurg Psychiatry. 1986 Sep;49(9):1074-6.

35.

Histidyl-proline, a rapidly degraded metabolite of thyrotropin releasing hormone, has behavioural activity.

Coggins PJ, Sahgal A, McDermott JR, Snell CR, Keith AB, Edwardson JA.

Pharmacol Biochem Behav. 1986 May;24(5):1229-33.

PMID:
3088606
36.

Molecular forms of somatostatin, substance P and neurotensin in fresh human cerebral cortex.

Bateman DE, McDermott JR, Smith AI, Biggins JA, Edwardson JA.

Regul Pept. 1986 May;14(3):211-6.

PMID:
2425398
37.

Peptidases involved in the catabolism of neurotensin: inhibitor studies using superfused rat hypothalamic slices.

McDermott JR, Virmani MA, Turner JD, Kidd AM.

Peptides. 1986 Mar-Apr;7(2):225-30.

PMID:
3526299
38.

Somatostatin immunoreactivity in cortical and some subcortical regions in Alzheimer's disease.

Candy JM, Gascoigne AD, Biggins JA, Smith AI, Perry RH, Perry EK, McDermott JR, Edwardson JA.

J Neurol Sci. 1985 Dec;71(2-3):315-23.

PMID:
2868073
39.

Purification and characterization of a neuropeptide-degrading aminopeptidase from human brain.

McDermott JR, Mantle D, Lauffart B, Kidd AM.

J Neurochem. 1985 Sep;45(3):752-9.

PMID:
4031861
40.

Specificity of neuropeptide degradation by two calcium-activated neutral proteases from human skeletal muscle.

McDermott JR, Mantle D, Biggins JA, Kidd AM, Davison K, Lauffart B, Pennington RJ.

Life Sci. 1985 Aug 26;37(8):725-30.

PMID:
2410757
41.

Purification and characterization of two Cl- -activated aminopeptidases hydrolysing basic termini from human skeletal muscle.

Mantle D, Lauffart B, McDermott JR, Kidd AM, Pennington RJ.

Eur J Biochem. 1985 Mar 1;147(2):307-12.

42.

Metabolism of neuropeptides at brain and pituitary sites.

Edwardson JA, McDermott JR.

Biochem Soc Trans. 1985 Feb;13(1):50-3. No abstract available.

PMID:
3888723
43.

Biotransformation of neuropeptides.

Griffths EC, McDermott JR.

Neuroendocrinology. 1984 Dec;39(6):573-81.

PMID:
6083500
44.

Chromatographic characterization of neuropeptides in post mortem human brain.

Biggins JA, McDermott JR, Smith AI, Candy JM, Perry RH, Bateman DE, Edwardson JA.

J Neurol Sci. 1984 Oct;66(1):47-58.

PMID:
6084049
46.
47.

A comparative study of neurotensin inactivation by brain peptidases from different vertebrate species.

Griffiths EC, McDermott JR, Smith AI.

Comp Biochem Physiol C. 1984;77(2):363-6.

PMID:
6144444
48.

Enzymic inactivation of hypothalamic regulatory hormones.

Griffiths EC, McDermott JR.

Mol Cell Endocrinol. 1983 Nov;33(1):1-25. Review.

PMID:
6416908
49.

Failure of gel filtration and HPLC purification to increase levels of immunoreactive TRH in rat brain extracts.

Court JA, Smith AI, McDermott JR, Biggins JA, Edwardson JA.

Peptides. 1983 Jul-Aug;4(4):585-7.

PMID:
6417633
50.

Purification and characterization of the major aminopeptidase from human skeletal muscle.

Mantle D, Hardy MF, Lauffart B, McDermott JR, Smith AI, Pennington RJ.

Biochem J. 1983 Jun 1;211(3):567-73.

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