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Items: 1 to 50 of 547

1.

Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation.

Austin JW, Buckner CM, Kardava L, Wang W, Zhang X, Melson VA, Swanson RG, Martins AJ, Zhou JQ, Hoehn KB, Fisk JN, Dimopoulos Y, Chassiakos A, O'Dell S, Smelkinson MG, Seamon CA, Kwan RW, Sneller MC, Pittaluga S, Doria-Rose NA, McDermott A, Li Y, Chun TW, Kleinstein SH, Tsang JS, Petrovas C, Moir S.

Sci Transl Med. 2019 Nov 27;11(520). pii: eaax0904. doi: 10.1126/scitranslmed.aax0904.

PMID:
31776286
2.

Hemagglutinin head-specific responses dominate over stem-specific responses following prime boost with mismatched vaccines.

Jegaskanda S, Andrews SF, Wheatley AK, Yewdell JW, McDermott AB, Subbarao K.

JCI Insight. 2019 Nov 14;4(22). pii: 129035. doi: 10.1172/jci.insight.129035.

3.

Science and Culture: Why "seeing" some scientific phenomena entails a touch of artistry and a dash of interpretation.

McDermott A.

Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):21953-21956. doi: 10.1073/pnas.1916741116. No abstract available.

4.

Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice.

Figueroa-Romero C, Guo K, Murdock BJ, Paez-Colasante X, Bassis CM, Mikhail KA, Raue KD, Evans MC, Taubman GF, McDermott AJ, O'Brien PD, Savelieff MG, Hur J, Feldman EL.

Dis Model Mech. 2019 Nov 15;13(2). pii: dmm041947. doi: 10.1242/dmm.041947.

5.

News Feature: Fighting a fungal scourge.

McDermott A.

Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20245-20249. doi: 10.1073/pnas.1915365116. No abstract available.

6.

TmDOTP: An NMR-based thermometer for magic angle spinning NMR experiments.

Zhang D, Itin B, McDermott AE.

J Magn Reson. 2019 Nov;308:106574. doi: 10.1016/j.jmr.2019.106574. Epub 2019 Aug 16.

PMID:
31541931
7.

Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair.

Herberg S, McDermott AM, Dang PN, Alt DS, Tang R, Dawahare JH, Varghai D, Shin JY, McMillan A, Dikina AD, He F, Lee YB, Cheng Y, Umemori K, Wong PC, Park H, Boerckel JD, Alsberg E.

Sci Adv. 2019 Aug 28;5(8):eaax2476. doi: 10.1126/sciadv.aax2476. eCollection 2019 Aug.

8.

Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial.

Gaudinski MR, Houser KV, Doria-Rose NA, Chen GL, Rothwell RSS, Berkowitz N, Costner P, Holman LA, Gordon IJ, Hendel CS, Kaltovich F, Conan-Cibotti M, Gomez Lorenzo M, Carter C, Sitar S, Carlton K, Gall J, Laurencot C, Lin BC, Bailer RT, McDermott AB, Ko SY, Pegu A, Kwon YD, Kwong PD, Namboodiri AM, Pandey JP, Schwartz R, Arnold F, Hu Z, Zhang L, Huang Y, Koup RA, Capparelli EV, Graham BS, Mascola JR, Ledgerwood JE; VRC 605 study team.

Lancet HIV. 2019 Oct;6(10):e667-e679. doi: 10.1016/S2352-3018(19)30181-X. Epub 2019 Aug 28.

PMID:
31473167
9.

First Pediatric Experience With a Novel, Adhesive Adapter Retained, Bone Conduction Hearing Aid System.

Osborne MS, Child-Hymas A, Gill J, Lloyd MS, McDermott AL.

Otol Neurotol. 2019 Oct;40(9):1199-1207. doi: 10.1097/MAO.0000000000002363.

PMID:
31469800
10.

Global identifiability of latent class models with applications to diagnostic test accuracy studies: A Gröbner basis approach.

Duan R, Cao M, Ning Y, Zhu M, Zhang B, McDermott A, Chu H, Zhou X, Moore JH, Ibrahim JG, Scharfstein DO, Chen Y.

Biometrics. 2019 Aug 24. doi: 10.1111/biom.13133. [Epub ahead of print]

PMID:
31444807
11.

Science and Culture: Light-seeking mobile houseplants raise big questions about the future of technology.

McDermott A.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15313-15315. doi: 10.1073/pnas.1909980116. No abstract available.

12.

Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin.

Andrews SF, Chambers MJ, Schramm CA, Plyler J, Raab JE, Kanekiyo M, Gillespie RA, Ransier A, Darko S, Hu J, Chen X, Yassine HM, Boyington JC, Crank MC, Chen GL, Coates E, Mascola JR, Douek DC, Graham BS, Ledgerwood JE, McDermott AB.

Immunity. 2019 Aug 20;51(2):398-410.e5. doi: 10.1016/j.immuni.2019.06.024. Epub 2019 Jul 23.

PMID:
31350180
13.

Influence of type 2 diabetes on muscle deoxygenation during ramp incremental cycle exercise.

Gildea N, Rocha J, McDermott A, O'Shea D, Green S, Egaña M.

Respir Physiol Neurobiol. 2019 Nov;269:103258. doi: 10.1016/j.resp.2019.103258. Epub 2019 Jul 23.

PMID:
31349019
14.

Infectious particle identity determines dissemination and disease outcome for the inhaled human fungal pathogen Cryptococcus.

Walsh NM, Botts MR, McDermott AJ, Ortiz SC, Wüthrich M, Klein B, Hull CM.

PLoS Pathog. 2019 Jun 27;15(6):e1007777. doi: 10.1371/journal.ppat.1007777. eCollection 2019 Jun.

15.

Science and Culture: Artists and scientists come together to explore the meaning of natural sound.

McDermott A.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12580-12583. doi: 10.1073/pnas.1908588116. No abstract available.

16.

News Feature: Probing the limits of "evolutionary rescue".

McDermott A.

Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12116-12120. doi: 10.1073/pnas.1907565116. No abstract available.

17.

Outflanking immunodominance to target subdominant broadly neutralizing epitopes.

Angeletti D, Kosik I, Santos JJS, Yewdell WT, Boudreau CM, Mallajosyula VVA, Mankowski MC, Chambers M, Prabhakaran M, Hickman HD, McDermott AB, Alter G, Chaudhuri J, Yewdell JW.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13474-13479. doi: 10.1073/pnas.1816300116. Epub 2019 Jun 18.

PMID:
31213541
18.

Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration.

McDermott AM, Herberg S, Mason DE, Collins JM, Pearson HB, Dawahare JH, Tang R, Patwa AN, Grinstaff MW, Kelly DJ, Alsberg E, Boerckel JD.

Sci Transl Med. 2019 Jun 5;11(495). pii: eaav7756. doi: 10.1126/scitranslmed.aav7756.

PMID:
31167930
19.

Stability of nitroxide biradical TOTAPOL in biological samples.

McCoy KM, Rogawski R, Stovicek O, McDermott AE.

J Magn Reson. 2019 Jun;303:115-120. doi: 10.1016/j.jmr.2019.04.013. Epub 2019 Apr 22.

PMID:
31039521
20.

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.

Matsuda K, Huang J, Zhou T, Sheng Z, Kang BH, Ishida E, Griesman T, Stuccio S, Bolkhovitinov L, Wohlbold TJ, Chromikova V, Cagigi A, Leung K, Andrews S, Cheung CSF, Pullano AA, Plyler J, Soto C, Zhang B, Yang Y, Joyce MG, Tsybovsky Y, Wheatley A, Narpala SR, Guo Y, Darko S, Bailer RT, Poole A, Liang CJ, Smith J, Alexander J, Gurwith M, Migueles SA, Koup RA, Golding H, Khurana S, McDermott AB, Shapiro L, Krammer F, Kwong PD, Connors M.

Sci Immunol. 2019 Apr 19;4(34). pii: eaau2710. doi: 10.1126/sciimmunol.aau2710.

PMID:
31004012
21.

Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial.

Crowell TA, Colby DJ, Pinyakorn S, Sacdalan C, Pagliuzza A, Intasan J, Benjapornpong K, Tangnaree K, Chomchey N, Kroon E, de Souza MS, Tovanabutra S, Rolland M, Eller MA, Paquin-Proulx D, Bolton DL, Tokarev A, Thomas R, Takata H, Trautmann L, Krebs SJ, Modjarrad K, McDermott AB, Bailer RT, Doria-Rose N, Patel B, Gorelick RJ, Fullmer BA, Schuetz A, Grandin PV, O'Connell RJ, Ledgerwood JE, Graham BS, Tressler R, Mascola JR, Chomont N, Michael NL, Robb ML, Phanuphak N, Ananworanich J; RV397 Study Group.

Lancet HIV. 2019 May;6(5):e297-e306. doi: 10.1016/S2352-3018(19)30053-0. Epub 2019 Apr 15.

PMID:
31000477
22.

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.

Kanekiyo M, Joyce MG, Gillespie RA, Gallagher JR, Andrews SF, Yassine HM, Wheatley AK, Fisher BE, Ambrozak DR, Creanga A, Leung K, Yang ES, Boyoglu-Barnum S, Georgiev IS, Tsybovsky Y, Prabhakaran MS, Andersen H, Kong WP, Baxa U, Zephir KL, Ledgerwood JE, Koup RA, Kwong PD, Harris AK, McDermott AB, Mascola JR, Graham BS.

Nat Immunol. 2019 Jun;20(6):765. doi: 10.1038/s41590-019-0395-0.

PMID:
30980067
23.

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells.

Bu W, Joyce MG, Nguyen H, Banh DV, Aguilar F, Tariq Z, Yap ML, Tsujimura Y, Gillespie RA, Tsybovsky Y, Andrews SF, Narpala SR, McDermott AB, Rossmann MG, Yasutomi Y, Nabel GJ, Kanekiyo M, Cohen JI.

Immunity. 2019 May 21;50(5):1305-1316.e6. doi: 10.1016/j.immuni.2019.03.010. Epub 2019 Apr 9.

PMID:
30979688
24.

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.

Hernández-Santos N, Wiesner DL, Fites JS, McDermott AJ, Warner T, Wüthrich M, Klein BS.

Cell Host Microbe. 2019 Apr 10;25(4):630. doi: 10.1016/j.chom.2019.03.013. No abstract available.

25.

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.

Lu M, Ma X, Castillo-Menendez LR, Gorman J, Alsahafi N, Ermel U, Terry DS, Chambers M, Peng D, Zhang B, Zhou T, Reichard N, Wang K, Grover JR, Carman BP, Gardner MR, Nikić-Spiegel I, Sugawara A, Arthos J, Lemke EA, Smith AB 3rd, Farzan M, Abrams C, Munro JB, McDermott AB, Finzi A, Kwong PD, Blanchard SC, Sodroski JG, Mothes W.

Nature. 2019 Apr;568(7752):415-419. doi: 10.1038/s41586-019-1101-y. Epub 2019 Apr 10.

26.

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.

Krebs SJ, Kwon YD, Schramm CA, Law WH, Donofrio G, Zhou KH, Gift S, Dussupt V, Georgiev IS, Schätzle S, McDaniel JR, Lai YT, Sastry M, Zhang B, Jarosinski MC, Ransier A, Chenine AL, Asokan M, Bailer RT, Bose M, Cagigi A, Cale EM, Chuang GY, Darko S, Driscoll JI, Druz A, Gorman J, Laboune F, Louder MK, McKee K, Mendez L, Moody MA, O'Sullivan AM, Owen C, Peng D, Rawi R, Sanders-Buell E, Shen CH, Shiakolas AR, Stephens T, Tsybovsky Y, Tucker C, Verardi R, Wang K, Zhou J, Zhou T, Georgiou G, Alam SM, Haynes BF, Rolland M, Matyas GR, Polonis VR, McDermott AB, Douek DC, Shapiro L, Tovanabutra S, Michael NL, Mascola JR, Robb ML, Kwong PD, Doria-Rose NA.

Immunity. 2019 Mar 19;50(3):677-691.e13. doi: 10.1016/j.immuni.2019.02.008. Epub 2019 Mar 12.

PMID:
30876875
27.

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages.

Corbett KS, Moin SM, Yassine HM, Cagigi A, Kanekiyo M, Boyoglu-Barnum S, Myers SI, Tsybovsky Y, Wheatley AK, Schramm CA, Gillespie RA, Shi W, Wang L, Zhang Y, Andrews SF, Joyce MG, Crank MC, Douek DC, McDermott AB, Mascola JR, Graham BS, Boyington JC.

MBio. 2019 Feb 26;10(1). pii: e02810-18. doi: 10.1128/mBio.02810-18.

28.

Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy.

de Armas LR, Pallikkuth S, Pan L, Rinaldi S, Cotugno N, Andrews S, Pahwa R, McDermott AB, Palma P, Pahwa S.

Sci Rep. 2019 Feb 21;9(1):2482. doi: 10.1038/s41598-019-38906-y.

29.

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.

Kanekiyo M, Joyce MG, Gillespie RA, Gallagher JR, Andrews SF, Yassine HM, Wheatley AK, Fisher BE, Ambrozak DR, Creanga A, Leung K, Yang ES, Boyoglu-Barnum S, Georgiev IS, Tsybovsky Y, Prabhakaran MS, Andersen H, Kong WP, Baxa U, Zephir KL, Ledgerwood JE, Koup RA, Kwong PD, Harris AK, McDermott AB, Mascola JR, Graham BS.

Nat Immunol. 2019 Mar;20(3):362-372. doi: 10.1038/s41590-018-0305-x. Epub 2019 Feb 11. Erratum in: Nat Immunol. 2019 Apr 12;:.

30.

Dynamic Perspectives on the Search for a Universal Influenza Vaccine.

Saad-Roy CM, McDermott AB, Grenfell BT.

J Infect Dis. 2019 Apr 8;219(Supplement_1):S46-S56. doi: 10.1093/infdis/jiz044.

PMID:
30715467
31.

Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study.

Gaudinski MR, Coates EE, Novik L, Widge A, Houser KV, Burch E, Holman LA, Gordon IJ, Chen GL, Carter C, Nason M, Sitar S, Yamshchikov G, Berkowitz N, Andrews C, Vazquez S, Laurencot C, Misasi J, Arnold F, Carlton K, Lawlor H, Gall J, Bailer RT, McDermott A, Capparelli E, Koup RA, Mascola JR, Graham BS, Sullivan NJ, Ledgerwood JE; VRC 608 Study team.

Lancet. 2019 Mar 2;393(10174):889-898. doi: 10.1016/S0140-6736(19)30036-4. Epub 2019 Jan 24.

PMID:
30686586
32.

Identifying coupled clusters of allostery participants through chemical shift perturbations.

Xu Y, Zhang D, Rogawski R, Nimigean CM, McDermott AE.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2078-2085. doi: 10.1073/pnas.1811168116. Epub 2019 Jan 24.

33.

Immunity to Influenza: Catching a Moving Target To Improve Vaccine Design.

Paules CI, McDermott AB, Fauci AS.

J Immunol. 2019 Jan 15;202(2):327-331. doi: 10.4049/jimmunol.1890025. No abstract available.

PMID:
30617113
34.

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, Wiehe K, Trama AM, Saunders KO, Gladden MA, Monroe A, Bonsignori M, Kanekiyo M, Wheatley AK, McDermott AB, Farney SK, Chuang GY, Zhang B, Kc N, Chakravarty S, Kwong PD, Sinnis P, Bhatia SN, Kappe SHI, Sim BKL, Hoffman SL, Zavala F, Pancera M, Seder RA.

Nat Med. 2019 Jan;25(1):188-189. doi: 10.1038/s41591-018-0315-0.

PMID:
30552419
35.

Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge.

Welles HC, Jennewein MF, Mason RD, Narpala S, Wang L, Cheng C, Zhang Y, Todd JP, Lifson JD, Balazs AB, Alter G, McDermott AB, Mascola JR, Roederer M.

PLoS Pathog. 2018 Dec 5;14(12):e1007395. doi: 10.1371/journal.ppat.1007395. eCollection 2018 Dec.

36.

Thermal Inactivation of Listeria monocytogenes in Crab Meat.

McDermott A, Whyte P, Brunton N, Bolton DJ.

J Food Prot. 2018 Dec;81(12):2003-2006. doi: 10.4315/0362-028X.JFP-18-276.

PMID:
30476441
37.

Pathology in Practice.

Elliott JE, McDermott AJ, Camus AC.

J Am Vet Med Assoc. 2018 Nov 15;253(10):1273-1275. doi: 10.2460/javma.253.10.1273. No abstract available.

PMID:
30398429
38.

Refocusing CSA during magic angle spinning rotating-frame relaxation experiments.

Keeler EG, Fritzsching KJ, McDermott AE.

J Magn Reson. 2018 Nov;296:130-137. doi: 10.1016/j.jmr.2018.09.004. Epub 2018 Sep 14.

39.

Will children ever learn? Removal of nasal and aural foreign bodies: a study of hospital episode statistics.

Morris S, Osborne MS, McDermott AL.

Ann R Coll Surg Engl. 2018 Jul 3:1-3. doi: 10.1308/rcsann.2018.0115. [Epub ahead of print]

40.

Clinical outcomes following Cochlear™ BIA300 bone anchored hearing aid implantation in children.

Fussey JM, Harterink E, Gill J, Child-Hymas A, McDermott AL.

Int J Pediatr Otorhinolaryngol. 2018 Aug;111:89-92. doi: 10.1016/j.ijporl.2018.05.033. Epub 2018 May 31.

PMID:
29958622
41.

Increasing the Yield of Irish Brown Crab (Cancer pagurus) during Processing without Adversely Affecting Shelf-Life.

McDermott A, Whyte P, Brunton N, Lyng J, Bolton DJ.

Foods. 2018 Jun 27;7(7). pii: E99. doi: 10.3390/foods7070099.

42.

The D-KEFS Trails as performance validity tests.

Erdodi LA, Hurtubise JL, Charron C, Dunn A, Enache A, McDermott A, Hirst RB.

Psychol Assess. 2018 Aug;30(8):1082-1095. doi: 10.1037/pas0000561. Epub 2018 Jun 28.

PMID:
29952596
43.

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.

Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, Chambers M, Chen X, Choi CW, Dandey VP, Doria-Rose NA, Druz A, Eng ET, Farney SK, Foulds KE, Geng H, Georgiev IS, Gorman J, Hill KR, Jafari AJ, Kwon YD, Lai YT, Lemmin T, McKee K, Ohr TY, Ou L, Peng D, Rowshan AP, Sheng Z, Todd JP, Tsybovsky Y, Viox EG, Wang Y, Wei H, Yang Y, Zhou AF, Chen R, Yang L, Scorpio DG, McDermott AB, Shapiro L, Carragher B, Potter CS, Mascola JR, Kwong PD.

Nat Med. 2018 Jun;24(6):857-867. doi: 10.1038/s41591-018-0042-6. Epub 2018 Jun 4.

44.

Short Tandem Repeat (STR) Profiles of Commonly Used Human Ocular Surface Cell Lines.

McDermott AM, Baidouri H, Woodward AM, Kam WR, Liu Y, Chen X, Ziemanski JF, Vistisen K, Hazlett LD, Nichols KK, Argüeso P, Sullivan DA.

Curr Eye Res. 2018 Sep;43(9):1097-1101. doi: 10.1080/02713683.2018.1480043. Epub 2018 Jun 4.

45.

Helper T-cell responses and pulmonary fungal infections.

McDermott AJ, Klein BS.

Immunology. 2018 Oct;155(2):155-163. doi: 10.1111/imm.12953. Epub 2018 Jun 14. Review.

46.

Croup: Diagnosis and Management.

Smith DK, McDermott AJ, Sullivan JF.

Am Fam Physician. 2018 May 1;97(9):575-580.

47.

Shaping a universally broad antibody response to influenza amidst a variable immunoglobulin landscape.

Andrews SF, McDermott AB.

Curr Opin Immunol. 2018 Aug;53:96-101. doi: 10.1016/j.coi.2018.04.009. Epub 2018 May 4. Review.

PMID:
29730560
48.

The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex.

Mompeán M, Li W, Li J, Laage S, Siemer AB, Bozkurt G, Wu H, McDermott AE.

Cell. 2018 May 17;173(5):1244-1253.e10. doi: 10.1016/j.cell.2018.03.032. Epub 2018 Apr 19.

49.

Accumulation of follicular CD8+ T cells in pathogenic SIV infection.

Ferrando-Martinez S, Moysi E, Pegu A, Andrews S, Nganou Makamdop K, Ambrozak D, McDermott AB, Palesch D, Paiardini M, Pavlakis GN, Brenchley JM, Douek D, Mascola JR, Petrovas C, Koup RA.

J Clin Invest. 2018 May 1;128(5):2089-2103. doi: 10.1172/JCI96207. Epub 2018 Apr 16.

50.

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.

Hernández-Santos N, Wiesner DL, Fites JS, McDermott AJ, Warner T, Wüthrich M, Klein BS.

Cell Host Microbe. 2018 Apr 11;23(4):511-522.e5. doi: 10.1016/j.chom.2018.02.011. Epub 2018 Mar 22. Erratum in: Cell Host Microbe. 2019 Apr 10;25(4):630.

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