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Items: 9


Discovery of a novel and potent class of anti-HIV-1 maturation inhibitors with improved virology profile against gag polymorphisms.

Tang J, Jones SA, Jeffrey JL, Miranda SR, Galardi CM, Irlbeck DM, Brown KW, McDanal CB, Johns BA.

Bioorg Med Chem Lett. 2017 Jun 15;27(12):2689-2694. doi: 10.1016/j.bmcl.2017.04.042. Epub 2017 Apr 20.


Synthesis and Biological Evaluation of Macrocyclized Betulin Derivatives as a Novel Class of Anti-HIV-1 Maturation Inhibitors.

Tang J, Jones SA, Jeffery JL, Miranda SR, Galardi CM, Irlbeck DM, Brown KW, McDanal CB, Han N, Gao D, Wu Y, Shen B, Liu C, Xi C, Yang H, Li R, Yu Y, Sun Y, Jin Z, Wang E, Johns BA.

Open Med Chem J. 2014 Sep 3;8:23-7. doi: 10.2174/1874104501408010023. eCollection 2014.


In vitro and clinical investigation of the relationship between CCR5 receptor occupancy and anti-HIV activity of Aplaviroc.

Demarest JF, Sparks SS, Schell K, Shibayama S, McDanal CB, Fang L, Adkison KK, Shachoy-Clark A, Piscitelli SC.

J Clin Pharmacol. 2008 Oct;48(10):1179-88. doi: 10.1177/0091270008322178. Epub 2008 Aug 1.


A distinctive clade B HIV type 1 is heterosexually transmitted in Trinidad and Tobago.

Cleghorn FR, Jack N, Carr JK, Edwards J, Mahabir B, Sill A, McDanal CB, Connolly SM, Goodman D, Bennetts RQ, O'Brien TR, Weinhold KJ, Bartholomew C, Blattner WA, Greenberg ML.

Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10532-7.


CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression.

Tomaras GD, Lacey SF, McDanal CB, Ferrari G, Weinhold KJ, Greenberg ML.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3503-8.


The CXC chemokine stromal cell-derived factor 1 is not responsible for CD8+ T cell suppression of syncytia-inducing strains of HIV-1.

Lacey SF, McDanal CB, Horuk R, Greenberg ML.

Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9842-7.


Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection.

Wild CT, Shugars DC, Greenwell TK, McDanal CB, Matthews TJ.

Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9770-4.


Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4.

Skinner MA, Langlois AJ, McDanal CB, McDougal JS, Bolognesi DP, Matthews TJ.

J Virol. 1988 Nov;62(11):4195-200.

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