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Development of transplant immunosuppressive agents - considerations in the use of animal models.

Costello R, Kissenpfennig A, Martins PN, McDaid J.

Expert Opin Drug Discov. 2018 Nov;13(11):1041-1053. doi: 10.1080/17460441.2018.1535589. Epub 2018 Oct 17. Review.


Heat Stroke as a Cause of Liver Failure and Evaluation of Liver Transplant.

Martins PN, Brüggenwirth IMA, McDaid J, Hertl M, Kawai T, Elias N, Chung RT, Markmann JF.

Exp Clin Transplant. 2018 Aug 17. doi: 10.6002/ect.2018.0003. [Epub ahead of print]


Long-Term Outcomes of Renal Transplant in Recipients With Lower Urinary Tract Dysfunction.

Wilson RS, Courtney AE, Ko DSC, Maxwell AP, McDaid J.

Exp Clin Transplant. 2019 Feb;17(1):11-17. doi: 10.6002/ect.2017.0137. Epub 2018 Jan 2.


Variability in iodine in temperate seaweeds and iodine accumulation kinetics of Fucus vesiculosus and Laminaria digitata (Phaeophyceae, Ochrophyta).

Nitschke U, Walsh P, McDaid J, Stengel DB.

J Phycol. 2018 Feb;54(1):114-125. doi: 10.1111/jpy.12606. Epub 2017 Dec 15.


Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum.

Abburi C, Wolfman SL, Metz RA, Kamber R, McGehee DS, McDaid J.

eNeuro. 2016 Aug 4;3(4). pii: ENEURO.0112-15.2016. doi: 10.1523/ENEURO.0112-15.2016. eCollection 2016 Jul-Aug.


Ethanol-Induced Motor Impairment Mediated by Inhibition of α7 Nicotinic Receptors.

McDaid J, Abburi C, Wolfman SL, Gallagher K, McGehee DS.

J Neurosci. 2016 Jul 20;36(29):7768-78. doi: 10.1523/JNEUROSCI.0154-16.2016.


Preoperative radial artery volume flow is predictive of arteriovenous fistula outcomes.

Masengu A, McDaid J, Maxwell AP, Hanko JB.

J Vasc Surg. 2016 Feb;63(2):429-35. doi: 10.1016/j.jvs.2015.08.106. Erratum in: J Vasc Surg. 2016 Apr;63(4):1133.


Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier.

Keaney J, Walsh DM, O'Malley T, Hudson N, Crosbie DE, Loftus T, Sheehan F, McDaid J, Humphries MM, Callanan JJ, Brett FM, Farrell MA, Humphries P, Campbell M.

Sci Adv. 2015 Sep 4;1(8):e1500472.


Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.

Thiele M, Kerschbaumer RJ, Tam FW, Völkel D, Douillard P, Schinagl A, Kühnel H, Smith J, McDaid JP, Bhangal G, Yu MC, Pusey CD, Cook HT, Kovarik J, Magelky E, Bhan A, Rieger M, Mudde GC, Ehrlich H, Jilma B, Tilg H, Moschen A, Terhorst C, Scheiflinger F.

J Immunol. 2015 Sep 1;195(5):2343-52. doi: 10.4049/jimmunol.1500572. Epub 2015 Jul 24.


A case report of primary ciliary dyskinesia, laterality defects and developmental delay caused by the co-existence of a single gene and chromosome disorder.

Casey JP, Goggin P, McDaid J, White M, Ennis S, Betts DR, Lucas JS, Elnazir B, Lynch SA.

BMC Med Genet. 2015 Jun 30;16:45. doi: 10.1186/s12881-015-0192-z.


The utility of animal models in developing immunosuppressive agents.

McDaid J, Scott CJ, Kissenpfennig A, Chen H, Martins PN.

Eur J Pharmacol. 2015 Jul 15;759:295-302. doi: 10.1016/j.ejphar.2015.03.025. Epub 2015 Mar 24. Review.


A chromosomal 5q31.1 gain involving PITX1 causes Liebenberg syndrome.

Seoighe DM, Gadancheva V, Regan R, McDaid J, Brenner C, Ennis S, Betts DR, Eadie PA, Lynch SA.

Am J Med Genet A. 2014 Nov;164A(11):2958-60. doi: 10.1002/ajmg.a.36712. Epub 2014 Aug 14. No abstract available.


Vocal cord paralysis in association with 9q34 duplication.

Gadancheva VG, Casey JP, Russell JD, McDaid J, Betts DR, Lynch SA.

Clin Dysmorphol. 2014 Jul;23(3):105-8. doi: 10.1097/MCD.0000000000000040. No abstract available.


Spleen tyrosine kinase inhibition attenuates autoantibody production and reverses experimental autoimmune GN.

McAdoo SP, Reynolds J, Bhangal G, Smith J, McDaid JP, Tanna A, Jackson WD, Masuda ES, Cook HT, Pusey CD, Tam FW.

J Am Soc Nephrol. 2014 Oct;25(10):2291-302. doi: 10.1681/ASN.2013090978. Epub 2014 Apr 3.


Left accessory hepatic artery damage by a misplaced gastric band in a deceased liver donor.

Martins PN, McDaid J, Markmann JF.

Transplantation. 2013 Sep;96(6):e45-6. doi: 10.1097/TP.0b013e3182a1c253. No abstract available.


Transitional cell carcinoma arising within a pediatric donor renal transplant in association with BK nephropathy.

McDaid J, Farkash EA, Steele DJ, Martins PN, Kotton CN, Elias N, Ko DS, Colvin RB, Hertl M.

Transplantation. 2013 Mar 15;95(5):e28-30. doi: 10.1097/TP.0b013e31828235ec. No abstract available.


A role for dopamine-mediated learning in the pathophysiology and treatment of Parkinson's disease.

Beeler JA, Frank MJ, McDaid J, Alexander E, Turkson S, Bernardez Sarria MS, McGehee DS, Zhuang X.

Cell Rep. 2012 Dec 27;2(6):1747-61. doi: 10.1016/j.celrep.2012.11.014. Epub 2012 Dec 13. Erratum in: Cell Rep. 2014 Jul 24;8(2):646. Bernandez, Maria Sol [corrected to Bernardez Sarria, Maria Sol].


Sickle cell and renal transplant: a national survey and literature review.

Nath J, McDaid J, Bentall A, Ball S, Ready AR, Inston NG.

Exp Clin Transplant. 2012 Feb;10(1):1-7. Review.


Mice with defective Fas ligand are protected from crescentic glomerulonephritis.

Tarzi RM, Sharp PE, McDaid JP, Fossati-Jimack L, Herbert PE, Pusey CD, Cook HT, Warrens AN.

Kidney Int. 2012 Jan;81(2):170-8. doi: 10.1038/ki.2011.319. Epub 2011 Sep 14.


DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.

Loughery JE, Dunne PD, O'Neill KM, Meehan RR, McDaid JR, Walsh CP.

Hum Mol Genet. 2011 Aug 15;20(16):3241-55. doi: 10.1093/hmg/ddr236. Epub 2011 Jun 2.


Diverticular fistulation is associated with nicorandil usage.

McDaid J, Reichl C, Hamzah I, Fitter S, Harbach L, Savage AP.

Ann R Coll Surg Engl. 2010 Sep;92(6):463-5. doi: 10.1308/003588410X12699663904673.


Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study.

Sunnotel O, Hiripi L, Lagan K, McDaid JR, De León JM, Miyagawa Y, Crowe H, Kaluskar S, Ward M, Scullion C, Campbell A, Downes CS, Hirst D, Barton D, Mocanu E, Tsujimura A, Cox MB, Robson T, Walsh CP.

Reprod Biol Endocrinol. 2010 Mar 8;8:22. doi: 10.1186/1477-7827-8-22.


A spleen tyrosine kinase inhibitor reduces the severity of established glomerulonephritis.

Smith J, McDaid JP, Bhangal G, Chawanasuntorapoj R, Masuda ES, Cook HT, Pusey CD, Tam FW.

J Am Soc Nephrol. 2010 Feb;21(2):231-6. doi: 10.1681/ASN.2009030263. Epub 2009 Dec 3.


Pkd2 dosage influences cellular repair responses following ischemia-reperfusion injury.

Prasad S, McDaid JP, Tam FW, Haylor JL, Ong AC.

Am J Pathol. 2009 Oct;175(4):1493-503. doi: 10.2353/ajpath.2009.090227. Epub 2009 Sep 3.


MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea.

McDaid JR, Loughery J, Dunne P, Boyer JC, Downes CS, Farber RA, Walsh CP.

Br J Cancer. 2009 Aug 4;101(3):441-51. doi: 10.1038/sj.bjc.6605186. Epub 2009 Jul 21. Erratum in: Br J Cancer. 2010 Mar 16;102(6):1080.


Generation of an epigenetic signature by chronic hypoxia in prostate cells.

Watson JA, Watson CJ, McCrohan AM, Woodfine K, Tosetto M, McDaid J, Gallagher E, Betts D, Baugh J, O'Sullivan J, Murrell A, Watson RW, McCann A.

Hum Mol Genet. 2009 Oct 1;18(19):3594-604. doi: 10.1093/hmg/ddp307. Epub 2009 Jul 7.


P2X7 deficiency attenuates renal injury in experimental glomerulonephritis.

Taylor SR, Turner CM, Elliott JI, McDaid J, Hewitt R, Smith J, Pickering MC, Whitehouse DL, Cook HT, Burnstock G, Pusey CD, Unwin RJ, Tam FW.

J Am Soc Nephrol. 2009 Jun;20(6):1275-81. doi: 10.1681/ASN.2008060559. Epub 2009 Apr 23.


Ethanol effects on dopaminergic ventral tegmental area neurons during block of Ih: involvement of barium-sensitive potassium currents.

McDaid J, McElvain MA, Brodie MS.

J Neurophysiol. 2008 Sep;100(3):1202-10. doi: 10.1152/jn.00994.2007. Epub 2008 Jul 9.


Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity.

Palmer CD, Mutch BE, Workman S, McDaid JP, Horwood NJ, Foxwell BM.

Blood. 2008 Feb 15;111(4):1781-8. Epub 2007 Nov 19.


Genes expressed by both mesangial cells and bone marrow-derived cells underlie genetic susceptibility to crescentic glomerulonephritis in the rat.

Smith J, Lai PC, Behmoaras J, Roufosse C, Bhangal G, McDaid JP, Aitman T, Tam FW, Pusey CD, Cook HT.

J Am Soc Nephrol. 2007 Jun;18(6):1816-23. Epub 2007 May 2.


Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1beta or IL-6.

Sheryanna A, Bhangal G, McDaid J, Smith J, Manning A, Foxwell BM, Feldmann M, Cook HT, Pusey CD, Tam FW.

J Am Soc Nephrol. 2007 Apr;18(4):1167-79. Epub 2007 Feb 21.


Pretransplant bilirubin concentration does not correlate with early reperfusion injury following liver transplantation.

Manzinate F, McDaid J, Devey L, Gunson B, Wigmore SJ.

Transplantation. 2007 Jan 15;83(1):103-4. No abstract available.


Methamphetamine-induced sensitization differentially alters pCREB and DeltaFosB throughout the limbic circuit of the mammalian brain.

McDaid J, Graham MP, Napier TC.

Mol Pharmacol. 2006 Dec;70(6):2064-74. Epub 2006 Sep 1.


Nullifying drug-induced sensitization: behavioral and electrophysiological evaluations of dopaminergic and serotonergic ligands in methamphetamine-sensitized rats.

McDaid J, Tedford CE, Mackie AR, Dallimore JE, Mickiewicz AL, Shen F, Angle JM, Napier TC.

Drug Alcohol Depend. 2007 Jan 5;86(1):55-66. Epub 2006 Jun 8.


The effects of long chain-length n-alcohols on the firing frequency of dopaminergic neurons of the ventral tegmental area.

Appel SB, Wise L, McDaid J, Koyama S, McElvain MA, Brodie MS.

J Pharmacol Exp Ther. 2006 Sep;318(3):1137-45. Epub 2006 Jun 1.


Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production.

Horwood NJ, Page TH, McDaid JP, Palmer CD, Campbell J, Mahon T, Brennan FM, Webster D, Foxwell BM.

J Immunol. 2006 Mar 15;176(6):3635-41.


Heme oxygenase-1 is essential for and promotes tolerance to transplanted organs.

Yamashita K, Ollinger R, McDaid J, Sakahama H, Wang H, Tyagi S, Csizmadia E, Smith NR, Soares MP, Bach FH.

FASEB J. 2006 Apr;20(6):776-8. Epub 2006 Feb 10.


Bilirubin: a natural inhibitor of vascular smooth muscle cell proliferation.

Ollinger R, Bilban M, Erat A, Froio A, McDaid J, Tyagi S, Csizmadia E, Graça-Souza AV, Liloia A, Soares MP, Otterbein LE, Usheva A, Yamashita K, Bach FH.

Circulation. 2005 Aug 16;112(7):1030-9. Epub 2005 Aug 8.


Donor treatment with carbon monoxide can yield islet allograft survival and tolerance.

Wang H, Lee SS, Gao W, Czismadia E, McDaid J, Ollinger R, Soares MP, Yamashita K, Bach FH.

Diabetes. 2005 May;54(5):1400-6.


Heme oxygenase-1 modulates the allo-immune response by promoting activation-induced cell death of T cells.

McDaid J, Yamashita K, Chora A, Ollinger R, Strom TB, Li XC, Bach FH, Soares MP.

FASEB J. 2005 Mar;19(3):458-60. Epub 2005 Jan 7.


Identification of 11 pseudogenes in the DNA methyltransferase gene family in rodents and humans and implications for the functional loci.

Lees-Murdock DJ, McLoughlin GA, McDaid JR, Quinn LM, O'Doherty A, Hiripi L, Hack CJ, Walsh CP.

Genomics. 2004 Jul;84(1):193-204.


Eosinophilic gastroenteritis presenting as obstructive jaundice.

Whitaker IS, Gulati A, McDaid JO, Bugajska-Carr U, Arends MJ.

Eur J Gastroenterol Hepatol. 2004 Apr;16(4):407-9.


Biliverdin, a natural product of heme catabolism, induces tolerance to cardiac allografts.

Yamashita K, McDaid J, Ollinger R, Tsui TY, Berberat PO, Usheva A, Csizmadia E, Smith RN, Soares MP, Bach FH.

FASEB J. 2004 Apr;18(6):765-7. Epub 2004 Feb 20.


PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation.

Firulli BA, Howard MJ, McDaid JR, McIlreavey L, Dionne KM, Centonze VE, Cserjesi P, Virshup DM, Firulli AB.

Mol Cell. 2003 Nov;12(5):1225-37.


Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production.

Horwood NJ, Mahon T, McDaid JP, Campbell J, Mano H, Brennan FM, Webster D, Foxwell BM.

J Exp Med. 2003 Jun 16;197(12):1603-11.


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