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Items: 15

1.

Smooth Muscle Cell-Mineralocorticoid Receptor as a Mediator of Cardiovascular Stiffness With Aging.

Kim SK, McCurley AT, DuPont JJ, Aronovitz M, Moss ME, Stillman IE, Karumanchi SA, Christou DD, Jaffe IZ.

Hypertension. 2018 Apr;71(4):609-621. doi: 10.1161/HYPERTENSIONAHA.117.10437. Epub 2018 Feb 20.

2.

Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury.

McCurley A, Alimperti S, Campos-Bilderback SB, Sandoval RM, Calvino JE, Reynolds TL, Quigley C, Mugford JW, Polacheck WJ, Gomez IG, Dovey J, Marsh G, Huang A, Qian F, Weinreb PH, Dolinski BM, Moore S, Duffield JS, Chen CS, Molitoris BA, Violette SM, Crackower MA.

J Am Soc Nephrol. 2017 Jun;28(6):1741-1752. doi: 10.1681/ASN.2016020200. Epub 2017 Jan 6.

3.

Vascular mineralocorticoid receptor regulates microRNA-155 to promote vasoconstriction and rising blood pressure with aging.

DuPont JJ, McCurley A, Davel AP, McCarthy J, Bender SB, Hong K, Yang Y, Yoo JK, Aronovitz M, Baur WE, Christou DD, Hill MA, Jaffe IZ.

JCI Insight. 2016 Sep 8;1(14):e88942. doi: 10.1172/jci.insight.88942.

4.

Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia.

Burke SD, Zsengellér ZK, Khankin EV, Lo AS, Rajakumar A, DuPont JJ, McCurley A, Moss ME, Zhang D, Clark CD, Wang A, Seely EW, Kang PM, Stillman IE, Jaffe IZ, Karumanchi SA.

J Clin Invest. 2016 Jul 1;126(7):2561-74. doi: 10.1172/JCI83918. Epub 2016 Jun 6.

5.

Exposure to experimental preeclampsia in mice enhances the vascular response to future injury.

Pruthi D, Khankin EV, Blanton RM, Aronovitz M, Burke SD, McCurley A, Karumanchi SA, Jaffe IZ.

Hypertension. 2015 Apr;65(4):863-70. doi: 10.1161/HYPERTENSIONAHA.114.04971. Epub 2015 Feb 23.

6.

Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function.

Barrett Mueller K, Lu Q, Mohammad NN, Luu V, McCurley A, Williams GH, Adler GK, Karas RH, Jaffe IZ.

Endocrinology. 2014 Nov;155(11):4461-72. doi: 10.1210/en.2014-1270. Epub 2014 Jul 22.

7.

Hydrogen sulfide attenuates sFlt1-induced hypertension and renal damage by upregulating vascular endothelial growth factor.

Holwerda KM, Burke SD, Faas MM, Zsengeller Z, Stillman IE, Kang PM, van Goor H, McCurley A, Jaffe IZ, Karumanchi SA, Lely AT.

J Am Soc Nephrol. 2014 Apr;25(4):717-25. doi: 10.1681/ASN.2013030291. Epub 2013 Dec 12.

8.

Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors.

Pruthi D, McCurley A, Aronovitz M, Galayda C, Karumanchi SA, Jaffe IZ.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):355-64. doi: 10.1161/ATVBAHA.113.302854. Epub 2013 Dec 5.

9.

Mineralocorticoid receptors in vascular disease: connecting molecular pathways to clinical implications.

McGraw AP, McCurley A, Preston IR, Jaffe IZ.

Curr Atheroscler Rep. 2013 Jul;15(7):340. doi: 10.1007/s11883-013-0340-x. Review.

10.

Direct contribution of vascular mineralocorticoid receptors to blood pressure regulation.

Barrett KV, McCurley AT, Jaffe IZ.

Clin Exp Pharmacol Physiol. 2013 Dec;40(12):902-9. doi: 10.1111/1440-1681.12125. Review.

11.

Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease.

McCurley A, McGraw A, Pruthi D, Jaffe IZ.

Pflugers Arch. 2013 Dec;465(12):1661-70. doi: 10.1007/s00424-013-1282-4. Epub 2013 May 1. Review.

12.

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors.

McCurley A, Pires PW, Bender SB, Aronovitz M, Zhao MJ, Metzger D, Chambon P, Hill MA, Dorrance AM, Mendelsohn ME, Jaffe IZ.

Nat Med. 2012 Sep;18(9):1429-33.

13.

Mineralocorticoid receptors in vascular function and disease.

McCurley A, Jaffe IZ.

Mol Cell Endocrinol. 2012 Mar 24;350(2):256-65. doi: 10.1016/j.mce.2011.06.014. Epub 2011 Jun 24. Review.

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