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Items: 1 to 50 of 139

1.

Prevalence, Risk Factors, and Outcomes of Bacteremic Pneumonia in Children.

Fritz CQ, Edwards KM, Self WH, Grijalva CG, Zhu Y, Arnold SR, McCullers JA, Ampofo K, Pavia AT, Wunderink RG, Anderson EJ, Bramley AM, Jain S, Williams DJ.

Pediatrics. 2019 Jul;144(1). pii: e20183090. doi: 10.1542/peds.2018-3090.

PMID:
31217309
2.

Enhanced IL-1╬▓ production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae.

Rodriguez AE, Bogart C, Gilbert CM, McCullers JA, Smith AM, Kanneganti TD, Lupfer CR.

PLoS One. 2019 Feb 22;14(2):e0212236. doi: 10.1371/journal.pone.0212236. eCollection 2019.

3.

Influenza: annual seasonal severity.

Gavigan P, McCullers JA.

Curr Opin Pediatr. 2019 Feb;31(1):112-118. doi: 10.1097/MOP.0000000000000712.

PMID:
30480557
4.

Prevalence of Staphylococcus aureus and Use of Antistaphylococcal Therapy in Children Hospitalized with Pneumonia.

Frush JM, Zhu Y, Edwards KM, Grijalva CG, Thomsen IP, Self WH, Jain S, Anderson EJ, Ampofo K, Pavia AT, Arnold SR, McCullers JA, Williams DJ.

J Hosp Med. 2018 Dec 1;13(12):848-852. doi: 10.12788/jhm.3093. Epub 2018 Oct 31.

5.

Use of Multiple Imputation to Estimate the Proportion of Respiratory Virus Detections Among Patients Hospitalized With Community-Acquired Pneumonia.

Bozio CH, Flanders WD, Finelli L, Bramley AM, Reed C, Gandhi NR, Vidal JE, Erdman D, Levine MZ, Lindstrom S, Ampofo K, Arnold SR, Self WH, Williams DJ, Grijalva CG, Anderson EJ, McCullers JA, Edwards KM, Pavia AT, Wunderink RG, Jain S.

Open Forum Infect Dis. 2018 Mar 16;5(4):ofy061. doi: 10.1093/ofid/ofy061. eCollection 2018 Apr.

6.

Mycoplasma pneumoniae Among Children Hospitalized With Community-acquired Pneumonia.

Kutty PK, Jain S, Taylor TH, Bramley AM, Diaz MH, Ampofo K, Arnold SR, Williams DJ, Edwards KM, McCullers JA, Pavia AT, Winchell JM, Schrag SJ, Hicks LA.

Clin Infect Dis. 2019 Jan 1;68(1):5-12. doi: 10.1093/cid/ciy419.

7.

Virulent PB1-F2 residues: effects on fitness of H1N1 influenza A virus in mice and changes during evolution of human influenza A viruses.

Alymova IV, McCullers JA, Kamal RP, Vogel P, Green AM, Gansebom S, York IA.

Sci Rep. 2018 May 10;8(1):7474. doi: 10.1038/s41598-018-25707-y.

8.

Etiology and Impact of Coinfections in Children Hospitalized With Community-Acquired Pneumonia.

Nolan VG, Arnold SR, Bramley AM, Ampofo K, Williams DJ, Grijalva CG, Self WH, Anderson EJ, Wunderink RG, Edwards KM, Pavia AT, Jain S, McCullers JA.

J Infect Dis. 2018 Jun 20;218(2):179-188. doi: 10.1093/infdis/jix641.

PMID:
29228381
9.

Effectiveness of ╬▓-Lactam Monotherapy vs Macrolide Combination Therapy for Children Hospitalized With Pneumonia.

Williams DJ, Edwards KM, Self WH, Zhu Y, Arnold SR, McCullers JA, Ampofo K, Pavia AT, Anderson EJ, Hicks LA, Bramley AM, Jain S, Grijalva CG.

JAMA Pediatr. 2017 Dec 1;171(12):1184-1191. doi: 10.1001/jamapediatrics.2017.3225.

10.

Rhinovirus Viremia in Patients Hospitalized With Community-Acquired Pneumonia.

Lu X, Schneider E, Jain S, Bramley AM, Hymas W, Stockmann C, Ampofo K, Arnold SR, Williams DJ, Self WH, Patel A, Chappell JD, Grijalva CG, Anderson EJ, Wunderink RG, McCullers JA, Edwards KM, Pavia AT, Erdman DD.

J Infect Dis. 2017 Nov 27;216(9):1104-1111. doi: 10.1093/infdis/jix455.

11.

Human Bocavirus Capsid Messenger RNA Detection in Children With Pneumonia.

Schlaberg R, Ampofo K, Tardif KD, Stockmann C, Simmon KE, Hymas W, Flygare S, Kennedy B, Blaschke A, Eilbeck K, Yandell M, McCullers JA, Williams DJ, Edwards K, Arnold SR, Bramley A, Jain S, Pavia AT.

J Infect Dis. 2017 Sep 15;216(6):688-696. doi: 10.1093/infdis/jix352.

12.

Low Retinol-Binding Protein and Vitamin D Levels Are Associated with Severe Outcomes in Children Hospitalized with Lower Respiratory Tract Infection and Respiratory Syncytial Virus or Human Metapneumovirus Detection.

Hurwitz JL, Jones BG, Penkert RR, Gansebom S, Sun Y, Tang L, Bramley AM, Jain S, McCullers JA, Arnold SR.

J Pediatr. 2017 Aug;187:323-327. doi: 10.1016/j.jpeds.2017.04.061. Epub 2017 May 31.

13.

Relationship Between Body Mass Index and Outcomes Among Hospitalized Patients With Community-Acquired Pneumonia.

Bramley AM, Reed C, Finelli L, Self WH, Ampofo K, Arnold SR, Williams DJ, Grijalva CG, Anderson EJ, Stockmann C, Trabue C, Fakhran S, Balk R, McCullers JA, Pavia AT, Edwards KM, Wunderink RG, Jain S; Centers for Disease Control and Prevention Etiology of Pneumonia in the Community (EPIC) Study Team.

J Infect Dis. 2017 Jun 15;215(12):1873-1882. doi: 10.1093/infdis/jix241.

14.

Influence of Antibiotics on the Detection of Bacteria by Culture-Based and Culture-Independent Diagnostic Tests in Patients Hospitalized With Community-Acquired Pneumonia.

Harris AM, Bramley AM, Jain S, Arnold SR, Ampofo K, Self WH, Williams DJ, Anderson EJ, Grijalva CG, McCullers JA, Pavia AT, Wunderink RG, Edwards KM, Winchell JM, Hicks LA.

Open Forum Infect Dis. 2017 Feb 10;4(1):ofx014. doi: 10.1093/ofid/ofx014. eCollection 2017 Winter.

15.

Oseltamivir Use Among Children and Adults Hospitalized With Community-Acquired Pneumonia.

Oboho IK, Bramley A, Finelli L, Fry A, Ampofo K, Arnold SR, Self WH, Williams DJ, Courtney DM, Zhu Y, Anderson EJ, Grijalva CG, McCullers JA, Wunderink RG, Pavia AT, Edwards KM, Jain S.

Open Forum Infect Dis. 2016 Dec 27;4(1):ofw254. doi: 10.1093/ofid/ofw254. eCollection 2017 Winter.

16.

Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus.

Samarasinghe AE, Melo RC, Duan S, LeMessurier KS, Liedmann S, Surman SL, Lee JJ, Hurwitz JL, Thomas PG, McCullers JA.

J Immunol. 2017 Apr 15;198(8):3214-3226. doi: 10.4049/jimmunol.1600787. Epub 2017 Mar 10.

17.

Procalcitonin Accurately Identifies Hospitalized Children With Low Risk of Bacterial Community-Acquired Pneumonia.

Stockmann C, Ampofo K, Killpack J, Williams DJ, Edwards KM, Grijalva CG, Arnold SR, McCullers JA, Anderson EJ, Wunderink RG, Self WH, Bramley A, Jain S, Pavia AT, Blaschke AJ.

J Pediatric Infect Dis Soc. 2018 Feb 19;7(1):46-53. doi: 10.1093/jpids/piw091.

18.

Glycosylation changes in the globular head of H3N2 influenza hemagglutinin modulate receptor binding without affecting virus virulence.

Alymova IV, York IA, Air GM, Cipollo JF, Gulati S, Baranovich T, Kumar A, Zeng H, Gansebom S, McCullers JA.

Sci Rep. 2016 Oct 31;6:36216. doi: 10.1038/srep36216.

19.

Serology Enhances Molecular Diagnosis of Respiratory Virus Infections Other than Influenza in Children and Adults Hospitalized with Community-Acquired Pneumonia.

Zhang Y, Sakthivel SK, Bramley A, Jain S, Haynes A, Chappell JD, Hymas W, Lenny N, Patel A, Qi C, Ampofo K, Arnold SR, Self WH, Williams DJ, Hillyard D, Anderson EJ, Grijalva CG, Zhu Y, Wunderink RG, Edwards KM, Pavia AT, McCullers JA, Erdman DD.

J Clin Microbiol. 2016 Dec 28;55(1):79-89. doi: 10.1128/JCM.01701-16. Print 2017 Jan.

20.

Predicting Severe Pneumonia Outcomes in Children.

Williams DJ, Zhu Y, Grijalva CG, Self WH, Harrell FE Jr, Reed C, Stockmann C, Arnold SR, Ampofo KK, Anderson EJ, Bramley AM, Wunderink RG, McCullers JA, Pavia AT, Jain S, Edwards KM.

Pediatrics. 2016 Oct;138(4). pii: e20161019.

21.

Antimicrobial peptides alter early immune response to influenza A virus infection in C57BL/6 mice.

LeMessurier KS, Lin Y, McCullers JA, Samarasinghe AE.

Antiviral Res. 2016 Sep;133:208-17. doi: 10.1016/j.antiviral.2016.08.013. Epub 2016 Aug 13.

22.

Association of sputum microbiota profiles with severity of community-acquired pneumonia in children.

Pettigrew MM, Gent JF, Kong Y, Wade M, Gansebom S, Bramley AM, Jain S, Arnold SL, McCullers JA.

BMC Infect Dis. 2016 Jul 8;16:317. doi: 10.1186/s12879-016-1670-4.

23.

The Role of Punctuated Evolution in the Pathogenicity of Influenza Viruses.

McCullers JA.

Microbiol Spectr. 2016 Apr;4(2). doi: 10.1128/microbiolspec.EI10-0001-2015. Review.

PMID:
27227306
24.

Identification of Bacterial and Viral Codetections With Mycoplasma pneumoniae Using the TaqMan Array Card in Patients Hospitalized With Community-Acquired Pneumonia.

Diaz MH, Cross KE, Benitez AJ, Hicks LA, Kutty P, Bramley AM, Chappell JD, Hymas W, Patel A, Qi C, Williams DJ, Arnold SR, Ampofo K, Self WH, Grijalva CG, Anderson EJ, McCullers JA, Pavia AT, Wunderink RG, Edwards KM, Jain S, Winchell JM.

Open Forum Infect Dis. 2016 Mar 30;3(2):ofw071. doi: 10.1093/ofid/ofw071. eCollection 2016 Mar.

25.

Immunogenicity and safety of high-dose trivalent inactivated influenza vaccine compared to standard-dose vaccine in children and young adults with cancer or HIV infection.

Hakim H, Allison KJ, Van de Velde LA, Tang L, Sun Y, Flynn PM, McCullers JA.

Vaccine. 2016 Jun 8;34(27):3141-3148. doi: 10.1016/j.vaccine.2016.04.053. Epub 2016 Apr 26.

26.

Community-Acquired Pneumonia Hospitalization among Children with Neurologic Disorders.

Millman AJ, Finelli L, Bramley AM, Peacock G, Williams DJ, Arnold SR, Grijalva CG, Anderson EJ, McCullers JA, Ampofo K, Pavia AT, Edwards KM, Jain S.

J Pediatr. 2016 Jun;173:188-195.e4. doi: 10.1016/j.jpeds.2016.02.049. Epub 2016 Mar 23.

27.

Molecular Detection and Characterization of Mycoplasma pneumoniae Among Patients Hospitalized With Community-Acquired Pneumonia in the United States.

Diaz MH, Benitez AJ, Cross KE, Hicks LA, Kutty P, Bramley AM, Chappell JD, Hymas W, Patel A, Qi C, Williams DJ, Arnold SR, Ampofo K, Self WH, Grijalva CG, Anderson EJ, McCullers JA, Pavia AT, Wunderink RG, Edwards KM, Jain S, Winchell JM.

Open Forum Infect Dis. 2015 Jul 16;2(3):ofv106. doi: 10.1093/ofid/ofv106. eCollection 2015 Sep.

28.

Secondhand Smoke Exposure and Illness Severity among Children Hospitalized with Pneumonia.

Ahn A, Edwards KM, Grijalva CG, Self WH, Zhu Y, Chappell JD, Arnold SR, McCullers JA, Ampofo K, Pavia AT, Bramley AM, Jain S, Williams DJ.

J Pediatr. 2015 Oct;167(4):869-874.e1. doi: 10.1016/j.jpeds.2015.06.049. Epub 2015 Jul 29.

29.

Glycosylation Analysis of Engineered H3N2 Influenza A Virus Hemagglutinins with Sequentially Added Historically Relevant Glycosylation Sites.

An Y, McCullers JA, Alymova I, Parsons LM, Cipollo JF.

J Proteome Res. 2015 Sep 4;14(9):3957-69. doi: 10.1021/acs.jproteome.5b00416. Epub 2015 Aug 10.

PMID:
26202417
30.

Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults.

Jain S, Self WH, Wunderink RG, Fakhran S, Balk R, Bramley AM, Reed C, Grijalva CG, Anderson EJ, Courtney DM, Chappell JD, Qi C, Hart EM, Carroll F, Trabue C, Donnelly HK, Williams DJ, Zhu Y, Arnold SR, Ampofo K, Waterer GW, Levine M, Lindstrom S, Winchell JM, Katz JM, Erdman D, Schneider E, Hicks LA, McCullers JA, Pavia AT, Edwards KM, Finelli L; CDC EPIC Study Team.

N Engl J Med. 2015 Jul 30;373(5):415-27. doi: 10.1056/NEJMoa1500245. Epub 2015 Jul 14.

31.

Antibiotic Choice for Children Hospitalized With Pneumonia and Adherence to National Guidelines.

Williams DJ, Edwards KM, Self WH, Zhu Y, Ampofo K, Pavia AT, Hersh AL, Arnold SR, McCullers JA, Hicks LA, Bramley AM, Jain S, Grijalva CG.

Pediatrics. 2015 Jul;136(1):44-52. doi: 10.1542/peds.2014-3047.

32.

Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway.

Hrincius ER, Liedmann S, Finkelstein D, Vogel P, Gansebom S, Samarasinghe AE, You D, Cormier SA, McCullers JA.

Cell Rep. 2015 Jun 16;11(10):1591-603. doi: 10.1016/j.celrep.2015.05.012. Epub 2015 Jun 4.

33.

Community-acquired pneumonia requiring hospitalization among U.S. children.

Jain S, Williams DJ, Arnold SR, Ampofo K, Bramley AM, Reed C, Stockmann C, Anderson EJ, Grijalva CG, Self WH, Zhu Y, Patel A, Hymas W, Chappell JD, Kaufman RA, Kan JH, Dansie D, Lenny N, Hillyard DR, Haynes LM, Levine M, Lindstrom S, Winchell JM, Katz JM, Erdman D, Schneider E, Hicks LA, Wunderink RG, Edwards KM, Pavia AT, McCullers JA, Finelli L; CDC EPIC Study Team.

N Engl J Med. 2015 Feb 26;372(9):835-45. doi: 10.1056/NEJMoa1405870.

34.

Comparison of immune response to the influenza vaccine in obese and nonobese healthcare workers.

Sweet MA, McCullers JA, Lasala PR, Briggs FE, Smithmyer A, Khakoo RA.

Infect Control Hosp Epidemiol. 2015 Mar;36(3):249-53. doi: 10.1017/ice.2014.59.

PMID:
25695164
35.

Randomized, double-blind comparison of standard-dose vs. high-dose trivalent inactivated influenza vaccine in pediatric solid organ transplant patients.

GiaQuinta S, Michaels MG, McCullers JA, Wang L, Fonnesbeck C, O'Shea A, Green M, Halasa NB.

Pediatr Transplant. 2015 Mar;19(2):219-28. doi: 10.1111/petr.12419. Epub 2014 Dec 18.

PMID:
25523718
36.

Live attenuated influenza virus increases pneumococcal translocation and persistence within the middle ear.

Mina MJ, Klugman KP, Rosch JW, McCullers JA.

J Infect Dis. 2015 Jul 15;212(2):195-201. doi: 10.1093/infdis/jiu804. Epub 2014 Dec 11.

37.

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions.

Liedmann S, Hrincius ER, Guy C, Anhlan D, Dierkes R, Carter R, Wu G, Staeheli P, Green DR, Wolff T, McCullers JA, Ludwig S, Ehrhardt C.

Nat Commun. 2014 Dec 9;5:5645. doi: 10.1038/ncomms6645.

38.

Non-avian animal reservoirs present a source of influenza A PB1-F2 proteins with novel virulence-enhancing markers.

Alymova IV, York IA, McCullers JA.

PLoS One. 2014 Nov 4;9(11):e111603. doi: 10.1371/journal.pone.0111603. eCollection 2014.

39.

Nonstructural protein 1 (NS1)-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections: insights into 1918 H1N1 pandemic?

Hrincius ER, Liedmann S, Finkelstein D, Vogel P, Gansebom S, Ehrhardt C, Ludwig S, Hains DS, Webby R, McCullers JA.

J Infect Dis. 2015 May 1;211(9):1418-28. doi: 10.1093/infdis/jiu609. Epub 2014 Nov 2.

PMID:
25367299
40.

Chronic helminth infections impair pneumococcal vaccine responses.

Apiwattanakul N, Thomas PG, Iverson AR, McCullers JA.

Vaccine. 2014 Sep 22;32(42):5405-10. doi: 10.1016/j.vaccine.2014.07.107. Epub 2014 Aug 13.

PMID:
25131738
41.

Secondary bacterial infections in influenza virus infection pathogenesis.

Smith AM, McCullers JA.

Curr Top Microbiol Immunol. 2014;385:327-56. doi: 10.1007/82_2014_394. Review.

PMID:
25027822
42.

The public health policy implications of understanding metabiosis.

McCullers JA.

Cell Host Microbe. 2014 Jul 9;16(1):3-4. doi: 10.1016/j.chom.2014.06.010.

43.

Helminth infections predispose mice to pneumococcal pneumonia but not to other pneumonic pathogens.

Apiwattanakul N, Thomas PG, Kuhn RE, Herbert DR, McCullers JA.

Med Microbiol Immunol. 2014 Oct;203(5):357-64. doi: 10.1007/s00430-014-0344-3. Epub 2014 Jun 21.

PMID:
24952091
44.

NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein.

Jaworska J, Coulombe F, Downey J, Tzelepis F, Shalaby K, Tattoli I, Berube J, Rousseau S, Martin JG, Girardin SE, McCullers JA, Divangahi M.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2110-9. doi: 10.1073/pnas.1322118111. Epub 2014 May 5.

45.

The co-pathogenesis of influenza viruses with bacteria in the lung.

McCullers JA.

Nat Rev Microbiol. 2014 Apr;12(4):252-62. doi: 10.1038/nrmicro3231. Epub 2014 Mar 3. Review.

PMID:
24590244
46.

Live attenuated influenza vaccine enhances colonization of Streptococcus pneumoniae and Staphylococcus aureus in mice.

Mina MJ, McCullers JA, Klugman KP.

MBio. 2014 Feb 18;5(1). pii: e01040-13. doi: 10.1128/mBio.01040-13.

47.

The immune profile associated with acute allergic asthma accelerates clearance of influenza virus.

Samarasinghe AE, Woolard SN, Boyd KL, Hoselton SA, Schuh JM, McCullers JA.

Immunol Cell Biol. 2014 May-Jun;92(5):449-59. doi: 10.1038/icb.2013.113. Epub 2014 Jan 28.

48.

A live-attenuated pneumococcal vaccine elicits CD4+ T-cell dependent class switching and provides serotype independent protection against acute otitis media.

Rosch JW, Iverson AR, Humann J, Mann B, Gao G, Vogel P, Mina M, Murrah KA, Perez AC, Edward Swords W, Tuomanen EI, McCullers JA.

EMBO Mol Med. 2014 Jan;6(1):141-54. doi: 10.1002/emmm.201202150.

49.

Adjunctive corticosteroid therapy improves lung immunopathology and survival during severe secondary pneumococcal pneumonia in mice.

Ghoneim HE, McCullers JA.

J Infect Dis. 2014 May 1;209(9):1459-68. doi: 10.1093/infdis/jit653. Epub 2013 Nov 23.

PMID:
24273183
50.

Safety of high dose trivalent inactivated influenza vaccine in pediatric patients with acute lymphoblastic leukemia.

McManus M, Frangoul H, McCullers JA, Wang L, O'Shea A, Halasa N.

Pediatr Blood Cancer. 2014 May;61(5):815-20. doi: 10.1002/pbc.24863. Epub 2013 Nov 19.

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