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Items: 17


Thymidine Kinase PET Reporter Gene Imaging of Cancer Cells In Vivo.

McCracken MN.

Methods Mol Biol. 2018;1790:137-151. doi: 10.1007/978-1-4939-7860-1_11.


PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.

Gordon SR, Maute RL, Dulken BW, Hutter G, George BM, McCracken MN, Gupta R, Tsai JM, Sinha R, Corey D, Ring AM, Connolly AJ, Weissman IL.

Nature. 2017 May 25;545(7655):495-499. doi: 10.1038/nature22396. Epub 2017 May 17.


Normal and Neoplastic Stem Cells.

McCracken MN, George BM, Kao KS, Marjon KD, Raveh T, Weissman IL.

Cold Spring Harb Symp Quant Biol. 2016;81:1-9. doi: 10.1101/sqb.2016.81.030965. Epub 2017 Apr 17. Review.


Practical Immuno-PET Radiotracer Design Considerations for Human Immune Checkpoint Imaging.

Mayer AT, Natarajan A, Gordon SR, Maute RL, McCracken MN, Ring AM, Weissman IL, Gambhir SS.

J Nucl Med. 2017 Apr;58(4):538-546. doi: 10.2967/jnumed.116.177659. Epub 2016 Dec 15.


Advances in PET Detection of the Antitumor T Cell Response.

McCracken MN, Tavaré R, Witte ON, Wu AM.

Adv Immunol. 2016;131:187-231. doi: 10.1016/ Epub 2016 Apr 5. Review.


Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo.

Zhang M, Hutter G, Kahn SA, Azad TD, Gholamin S, Xu CY, Liu J, Achrol AS, Richard C, Sommerkamp P, Schoen MK, McCracken MN, Majeti R, Weissman I, Mitra SS, Cheshier SH.

PLoS One. 2016 Apr 19;11(4):e0153550. doi: 10.1371/journal.pone.0153550. eCollection 2016.


Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging.

Maute RL, Gordon SR, Mayer AT, McCracken MN, Natarajan A, Ring NG, Kimura R, Tsai JM, Manglik A, Kruse AC, Gambhir SS, Weissman IL, Ring AM.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6506-14. doi: 10.1073/pnas.1519623112. Epub 2015 Nov 10.


An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.

Tavaré R, Escuin-Ordinas H, Mok S, McCracken MN, Zettlitz KA, Salazar FB, Witte ON, Ribas A, Wu AM.

Cancer Res. 2016 Jan 1;76(1):73-82. doi: 10.1158/0008-5472.CAN-15-1707. Epub 2015 Nov 16.


Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 "Don't Eat Me" Signals.

McCracken MN, Cha AC, Weissman IL.

Clin Cancer Res. 2015 Aug 15;21(16):3597-601. doi: 10.1158/1078-0432.CCR-14-2520. Epub 2015 Jun 26.


Immuno-PET of Murine T Cell Reconstitution Postadoptive Stem Cell Transplantation Using Anti-CD4 and Anti-CD8 Cys-Diabodies.

Tavaré R, McCracken MN, Zettlitz KA, Salazar FB, Olafsen T, Witte ON, Wu AM.

J Nucl Med. 2015 Aug;56(8):1258-64. doi: 10.2967/jnumed.114.153338. Epub 2015 May 7.


Targeted noninvasive imaging of the innate immune response.

McCracken MN, Radu CG.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):5868-9. doi: 10.1073/pnas.1505899112. Epub 2015 May 1. No abstract available.


Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.

McCracken MN, Vatakis DN, Dixit D, McLaughlin J, Zack JA, Witte ON.

J Clin Invest. 2015 May;125(5):1815-26. doi: 10.1172/JCI77326. Epub 2015 Mar 30.


Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance.

Bunimovich YL, Nair-Gill E, Riedinger M, McCracken MN, Cheng D, McLaughlin J, Radu CG, Witte ON.

PLoS One. 2014 Aug 7;9(8):e104125. doi: 10.1371/journal.pone.0104125. eCollection 2014.


HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice.

Gschweng EH, McCracken MN, Kaufman ML, Ho M, Hollis RP, Wang X, Saini N, Koya RC, Chodon T, Ribas A, Witte ON, Kohn DB.

Cancer Res. 2014 Sep 15;74(18):5173-83. doi: 10.1158/0008-5472.CAN-14-0376. Epub 2014 Jul 18.


Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver.

Clark PM, Flores G, Evdokimov NM, McCracken MN, Chai T, Nair-Gill E, O'Mahony F, Beaven SW, Faull KF, Phelps ME, Jung ME, Witte ON.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2866-74. doi: 10.1073/pnas.1410326111. Epub 2014 Jun 30.


Engineered antibody fragments for immuno-PET imaging of endogenous CD8+ T cells in vivo.

Tavaré R, McCracken MN, Zettlitz KA, Knowles SM, Salazar FB, Olafsen T, Witte ON, Wu AM.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1108-13. doi: 10.1073/pnas.1316922111. Epub 2014 Jan 3.


Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene.

McCracken MN, Gschweng EH, Nair-Gill E, McLaughlin J, Cooper AR, Riedinger M, Cheng D, Nosala C, Kohn DB, Witte ON.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1857-62. doi: 10.1073/pnas.1221840110. Epub 2013 Jan 14.

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