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Items: 1 to 50 of 120


The effects of metformin on age-related changes in the liver sinusoidal endothelial cell.

Hunt NJ, Lockwood GP, Kang SWS, Pulpitel T, Clark X, Mao H, McCourt PAG, Cooney GJ, Wali JA, Le Couteur FH, Le Couteur DG, Cogger VC.

J Gerontol A Biol Sci Med Sci. 2019 Jun 14. pii: glz153. doi: 10.1093/gerona/glz153. [Epub ahead of print]


Variable cytoplasmic actin expression impacts the sensitivity of different dystrophin-deficient mdx skeletal muscles to eccentric contraction.

Lindsay A, Southern WM, McCourt PM, Larson AA, Hodges JS, Lowe DA, Ervasti JM.

FEBS J. 2019 Jul;286(13):2562-2576. doi: 10.1111/febs.14831. Epub 2019 Apr 11.


Distinct mechanical properties in homologous spectrin-like repeats of utrophin.

Rajaganapathy S, McCourt JL, Ghosal S, Lindsay A, McCourt PM, Lowe DA, Ervasti JM, Salapaka MV.

Sci Rep. 2019 Mar 26;9(1):5210. doi: 10.1038/s41598-019-41569-4.


A femtomolar-range suicide germination stimulant for the parasitic plant Striga hermonthica.

Uraguchi D, Kuwata K, Hijikata Y, Yamaguchi R, Imaizumi H, Am S, Rakers C, Mori N, Akiyama K, Irle S, McCourt P, Kinoshita T, Ooi T, Tsuchiya Y.

Science. 2018 Dec 14;362(6420):1301-1305. doi: 10.1126/science.aau5445.


Xanthine oxidase is hyper-active in Duchenne muscular dystrophy.

Lindsay A, McCourt PM, Karachunski P, Lowe DA, Ervasti JM.

Free Radic Biol Med. 2018 Dec;129:364-371. doi: 10.1016/j.freeradbiomed.2018.10.404. Epub 2018 Oct 10.


Manipulating fenestrations in young and old liver sinusoidal endothelial cells.

Hunt NJ, Lockwood GP, Warren A, Mao H, McCourt PAG, Le Couteur DG, Cogger VC.

Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G144-G154. doi: 10.1152/ajpgi.00179.2018. Epub 2018 Oct 4.


Novel targets for delaying aging: The importance of the liver and advances in drug delivery.

Hunt NJ, McCourt PAG, Le Couteur DG, Cogger VC.

Adv Drug Deliv Rev. 2018 Oct;135:39-49. doi: 10.1016/j.addr.2018.09.006. Epub 2018 Sep 21. Review.


Plant Chemical Biology.

Kinoshita T, McCourt P, Asami T, Torii KU.

Plant Cell Physiol. 2018 Aug 1;59(8):1483-1486. doi: 10.1093/pcp/pcy142. No abstract available.


Chemical Screening for Strigolactone Receptor Antagonists Using Arabidopsis thaliana.

Holbrook-Smith D, McCourt P.

Methods Mol Biol. 2018;1795:117-126. doi: 10.1007/978-1-4939-7874-8_10.


Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms.

O'Rourke AR, Lindsay A, Tarpey MD, Yuen S, McCourt P, Nelson DM, Perrin BJ, Thomas DD, Spangenburg EE, Lowe DA, Ervasti JM.

FEBS J. 2018 Feb;285(3):481-500. doi: 10.1111/febs.14367. Epub 2018 Jan 8.


Mouse models of two missense mutations in actin-binding domain 1 of dystrophin associated with Duchenne or Becker muscular dystrophy.

McCourt JL, Talsness DM, Lindsay A, Arpke RW, Chatterton PD, Nelson DM, Chamberlain CM, Olthoff JT, Belanto JJ, McCourt PM, Kyba M, Lowe DA, Ervasti JM.

Hum Mol Genet. 2018 Feb 1;27(3):451-462. doi: 10.1093/hmg/ddx414.


Chemical genetics and strigolactone perception.

Lumba S, Bunsick M, McCourt P.

F1000Res. 2017 Jun 22;6:975. doi: 10.12688/f1000research.11379.1. eCollection 2017. Review.


The perception of strigolactones in vascular plants.

Lumba S, Holbrook-Smith D, McCourt P.

Nat Chem Biol. 2017 May 17;13(6):599-606. doi: 10.1038/nchembio.2340. Review.


Found in Translation: Applying Lessons from Model Systems to Strigolactone Signaling in Parasitic Plants.

Lumba S, Subha A, McCourt P.

Trends Biochem Sci. 2017 Jul;42(7):556-565. doi: 10.1016/j.tibs.2017.04.006. Epub 2017 May 9. Review.


Independent variability of microtubule perturbations associated with dystrophinopathy.

Belanto JJ, Olthoff JT, Mader TL, Chamberlain CM, Nelson DM, McCourt PM, Talsness DM, Gundersen GG, Lowe DA, Ervasti JM.

Hum Mol Genet. 2016 Nov 15;25(22):4951-4961. doi: 10.1093/hmg/ddw318.


Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence.

McCourt P, Liu HY, Parker JE, Gallo-Ebert C, Donigan M, Bata A, Giordano C, Kelly SL, Nickels JT Jr.

G3 (Bethesda). 2016 Nov 8;6(11):3455-3465. doi: 10.1534/g3.116.033969.


Farnesylation mediates brassinosteroid biosynthesis to regulate abscisic acid responses.

Northey JG, Liang S, Jamshed M, Deb S, Foo E, Reid JB, McCourt P, Samuel MA.

Nat Plants. 2016 Jul 25;2:16114. doi: 10.1038/nplants.2016.114.


Small-molecule antagonists of germination of the parasitic plant Striga hermonthica.

Holbrook-Smith D, Toh S, Tsuchiya Y, McCourt P.

Nat Chem Biol. 2016 Sep;12(9):724-9. doi: 10.1038/nchembio.2129. Epub 2016 Jul 18.


The ERF11 Transcription Factor Promotes Internode Elongation by Activating Gibberellin Biosynthesis and Signaling.

Zhou X, Zhang ZL, Park J, Tyler L, Yusuke J, Qiu K, Nam EA, Lumba S, Desveaux D, McCourt P, Kamiya Y, Sun TP.

Plant Physiol. 2016 Aug;171(4):2760-70. doi: 10.1104/pp.16.00154. Epub 2016 Jun 2.


The Small Molecule Hyperphyllin Enhances Leaf Formation Rate and Mimics Shoot Meristem Integrity Defects Associated with AMP1 Deficiency.

Poretska O, Yang S, Pitorre D, Rozhon W, Zwerger K, Uribe MC, May S, McCourt P, Poppenberger B, Sieberer T.

Plant Physiol. 2016 Jun;171(2):1277-90. doi: 10.1104/pp.15.01633. Epub 2016 May 3.


50 years of Arabidopsis research: highlights and future directions.

Provart NJ, Alonso J, Assmann SM, Bergmann D, Brady SM, Brkljacic J, Browse J, Chapple C, Colot V, Cutler S, Dangl J, Ehrhardt D, Friesner JD, Frommer WB, Grotewold E, Meyerowitz E, Nemhauser J, Nordborg M, Pikaard C, Shanklin J, Somerville C, Stitt M, Torii KU, Waese J, Wagner D, McCourt P.

New Phytol. 2016 Feb;209(3):921-44. doi: 10.1111/nph.13687. Epub 2015 Oct 14. Review.


Structure-function analysis identifies highly sensitive strigolactone receptors in Striga.

Toh S, Holbrook-Smith D, Stogios PJ, Onopriyenko O, Lumba S, Tsuchiya Y, Savchenko A, McCourt P.

Science. 2015 Oct 9;350(6257):203-7. doi: 10.1126/science.aac9476.


PARASITIC PLANTS. Probing strigolactone receptors in Striga hermonthica with fluorescence.

Tsuchiya Y, Yoshimura M, Sato Y, Kuwata K, Toh S, Holbrook-Smith D, Zhang H, McCourt P, Itami K, Kinoshita T, Hagihara S.

Science. 2015 Aug 21;349(6250):864-8. doi: 10.1126/science.aab3831.


Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage.

Ahluwalia BS, McCourt P, Oteiza A, Wilkinson JS, Huser TR, Hellesø OG.

Analyst. 2015 Jan 7;140(1):223-9. doi: 10.1039/c4an01181c.


Isolation of murine bone marrow scavenging sinusoidal endothelial cells.

McCourt PA, Oteiza A, Cao B, Nilsson SK.

Methods Mol Biol. 2015;1235:59-71. doi: 10.1007/978-1-4939-1785-3_6.


Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta.

Simon-Santamaria J, Rinaldo CH, Kardas P, Li R, Malovic I, Elvevold K, McCourt P, Smedsrød B, Hirsch HH, Sørensen KK.

PLoS One. 2014 Nov 6;9(11):e111762. doi: 10.1371/journal.pone.0111762. eCollection 2014.


Towards personalized agriculture: what chemical genomics can bring to plant biotechnology.

Stokes ME, McCourt P.

Front Plant Sci. 2014 Jul 11;5:344. doi: 10.3389/fpls.2014.00344. eCollection 2014.


Detection of parasitic plant suicide germination compounds using a high-throughput Arabidopsis HTL/KAI2 strigolactone perception system.

Toh S, Holbrook-Smith D, Stokes ME, Tsuchiya Y, McCourt P.

Chem Biol. 2014 Aug 14;21(8):988-98. doi: 10.1016/j.chembiol.2014.07.005. Epub 2014 Aug 7. Erratum in: Chem Biol. 2014 Sep 18;21(9):1253.


Imaging fenestrations in liver sinusoidal endothelial cells by optical localization microscopy.

Mönkemöller V, Schüttpelz M, McCourt P, Sørensen K, Smedsrød B, Huser T.

Phys Chem Chem Phys. 2014 Jun 28;16(24):12576-81. doi: 10.1039/c4cp01574f.


A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis.

Lumba S, Toh S, Handfield LF, Swan M, Liu R, Youn JY, Cutler SR, Subramaniam R, Provart N, Moses A, Desveaux D, McCourt P.

Dev Cell. 2014 May 12;29(3):360-72. doi: 10.1016/j.devcel.2014.04.004.


ABI3 controls embryo degreening through Mendel's I locus.

Delmas F, Sankaranarayanan S, Deb S, Widdup E, Bournonville C, Bollier N, Northey JG, McCourt P, Samuel MA.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3888-94. doi: 10.1073/pnas.1308114110. Epub 2013 Sep 16.


Characterization of a cruciferin deficient mutant of Arabidopsis and its utility for overexpression of foreign proteins in plants.

Lin Y, Pajak A, Marsolais F, McCourt P, Riggs CD.

PLoS One. 2013 May 27;8(5):e64980. doi: 10.1371/journal.pone.0064980. Print 2013.


Hepatic disposal of advanced glycation end products during maturation and aging.

Svistounov D, Oteiza A, Zykova SN, Sørensen KK, McCourt P, McLachlan AJ, McCuskey RS, Smedsrød B.

Exp Gerontol. 2013 Jun;48(6):549-56. doi: 10.1016/j.exger.2013.03.005. Epub 2013 Mar 24.


PP2A(Cdc55) regulates G1 cyclin stability.

McCourt P, Gallo-Ebert C, Gonghong Y, Jiang Y, Nickels JT Jr.

Cell Cycle. 2013 Apr 15;12(8):1201-10. doi: 10.4161/cc.24231. Epub 2013 Mar 21.


Forward genetic screening for the improved production of fermentable sugars from plant biomass.

Stamatiou G, Vidaurre DP, Shim I, Tang X, Moeder W, Bonetta D, McCourt P.

PLoS One. 2013;8(1):e55616. doi: 10.1371/journal.pone.0055616. Epub 2013 Jan 31.


The scavenger endothelial cell: a new player in homeostasis and immunity.

Sørensen KK, McCourt P, Berg T, Crossley C, Le Couteur D, Wake K, Smedsrød B.

Am J Physiol Regul Integr Comp Physiol. 2012 Dec 15;303(12):R1217-30. doi: 10.1152/ajpregu.00686.2011. Epub 2012 Oct 17. Review.


HY5 is involved in strigolactone-dependent seed germination in Arabidopsis.

Toh S, McCourt P, Tsuchiya Y.

Plant Signal Behav. 2012 May;7(5):556-8. doi: 10.4161/psb.19839. Epub 2012 Apr 20.


The embryonic leaf identity gene FUSCA3 regulates vegetative phase transitions by negatively modulating ethylene-regulated gene expression in Arabidopsis.

Lumba S, Tsuchiya Y, Delmas F, Hezky J, Provart NJ, Shi Lu Q, McCourt P, Gazzarrini S.

BMC Biol. 2012 Feb 20;10:8. doi: 10.1186/1741-7007-10-8.


Thermoinhibition uncovers a role for strigolactones in Arabidopsis seed germination.

Toh S, Kamiya Y, Kawakami N, Nambara E, McCourt P, Tsuchiya Y.

Plant Cell Physiol. 2012 Jan;53(1):107-17. doi: 10.1093/pcp/pcr176. Epub 2011 Dec 14.


Arv1 lipid transporter function is conserved between pathogenic and nonpathogenic fungi.

Gallo-Ebert C, McCourt PC, Donigan M, Villasmil ML, Chen W, Pandya D, Franco J, Romano D, Chadwick SG, Gygax SE, Nickels JT Jr.

Fungal Genet Biol. 2012 Feb;49(2):101-13. doi: 10.1016/j.fgb.2011.11.006. Epub 2011 Nov 27.


Strigolactones as small molecule communicators.

Tsuchiya Y, McCourt P.

Mol Biosyst. 2012 Feb;8(2):464-9. doi: 10.1039/c1mb05195d. Epub 2011 Oct 25. Review.


Next-generation mapping of Arabidopsis genes.

Austin RS, Vidaurre D, Stamatiou G, Breit R, Provart NJ, Bonetta D, Zhang J, Fung P, Gong Y, Wang PW, McCourt P, Guttman DS.

Plant J. 2011 Aug;67(4):715-25. doi: 10.1111/j.1365-313X.2011.04619.x. Epub 2011 Jul 18.


Posterior ankle impingement syndrome: a clinical review with reference to horizontal jump athletes.

Rogers J, Dijkstra P, Mccourt P, Connell D, Brice P, Ribbans W, Hamilton B.

Acta Orthop Belg. 2010 Oct;76(5):572-9. Review.


Role of liver sinusoidal endothelial cells and stabilins in elimination of oxidized low-density lipoproteins.

Li R, Oteiza A, Sørensen KK, McCourt P, Olsen R, Smedsrød B, Svistounov D.

Am J Physiol Gastrointest Liver Physiol. 2011 Jan;300(1):G71-81. doi: 10.1152/ajpgi.00215.2010. Epub 2010 Oct 28.


Optical trapping and propulsion of red blood cells on waveguide surfaces.

Ahluwalia BS, McCourt P, Huser T, Hellesø OG.

Opt Express. 2010 Sep 27;18(20):21053-61. doi: 10.1364/OE.18.021053.


A small-molecule screen identifies new functions for the plant hormone strigolactone.

Tsuchiya Y, Vidaurre D, Toh S, Hanada A, Nambara E, Kamiya Y, Yamaguchi S, McCourt P.

Nat Chem Biol. 2010 Oct;6(10):741-9. doi: 10.1038/nchembio.435. Epub 2010 Sep 5.


Plant nuclear hormone receptors: a role for small molecules in protein-protein interactions.

Lumba S, Cutler S, McCourt P.

Annu Rev Cell Dev Biol. 2010;26:445-69. doi: 10.1146/annurev-cellbio-100109-103956. Review.


Age-related changes in scavenger receptor-mediated endocytosis in rat liver sinusoidal endothelial cells.

Simon-Santamaria J, Malovic I, Warren A, Oteiza A, Le Couteur D, Smedsrød B, McCourt P, Sørensen KK.

J Gerontol A Biol Sci Med Sci. 2010 Sep;65(9):951-60. doi: 10.1093/gerona/glq108. Epub 2010 Jun 24.


Three-dimensional structured illumination microscopy of liver sinusoidal endothelial cell fenestrations.

Cogger VC, McNerney GP, Nyunt T, DeLeve LD, McCourt P, Smedsrød B, Le Couteur DG, Huser TR.

J Struct Biol. 2010 Sep;171(3):382-8. doi: 10.1016/j.jsb.2010.06.001. Epub 2010 Jun 4.

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