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Items: 1 to 50 of 115

1.

Hyperpolarized 3 He MRI Ventilatory Apparent Diffusion Coefficient of Alpha-1 Antitrypsin Deficiency.

Westcott A, Capaldi DPI, Ouriadov A, Westcott A, Capaldi DPI, McCormack DG, Parraga G.

J Magn Reson Imaging. 2018 Aug 13. doi: 10.1002/jmri.26202. [Epub ahead of print] No abstract available.

PMID:
30102430
2.

Development of a pulmonary imaging biomarker pipeline for phenotyping of chronic lung disease.

Guo F, Capaldi D, Kirby M, Sheikh K, Svenningsen S, McCormack DG, Fenster A, Parraga G; Canadian Respiratory Research Network.

J Med Imaging (Bellingham). 2018 Apr;5(2):026002. doi: 10.1117/1.JMI.5.2.026002. Epub 2018 Jun 28.

PMID:
29963580
3.

What is the minimal clinically important difference for helium-3 magnetic resonance imaging ventilation defects?

Eddy RL, Svenningsen S, McCormack DG, Parraga G.

Eur Respir J. 2018 Jun 28;51(6). pii: 1800324. doi: 10.1183/13993003.00324-2018. Print 2018 Jun. No abstract available.

PMID:
29650564
4.

Free-breathing Pulmonary MR Imaging to Quantify Regional Ventilation.

Capaldi DPI, Eddy RL, Svenningsen S, Guo F, Baxter JSH, McLeod AJ, Nair P, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Radiology. 2018 May;287(2):693-704. doi: 10.1148/radiol.2018171993. Epub 2018 Feb 22.

PMID:
29470939
5.

On the Potential Role of MRI Biomarkers of COPD to Guide Bronchoscopic Lung Volume Reduction.

Adams CJ, Capaldi DPI, Di Cesare R, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Acad Radiol. 2018 Feb;25(2):159-168. doi: 10.1016/j.acra.2017.08.010. Epub 2017 Oct 16.

PMID:
29051040
6.

Pulmonary 3He Magnetic Resonance Imaging Biomarkers of Regional Airspace Enlargement in Alpha-1 Antitrypsin Deficiency.

Lessard E, Young HM, Bhalla A, Pike D, Sheikh K, McCormack DG, Ouriadov A, Parraga G.

Acad Radiol. 2017 Nov;24(11):1402-1411. doi: 10.1016/j.acra.2017.05.008. Epub 2017 Jun 20.

PMID:
28645458
7.

Free-breathing Functional Pulmonary MRI: Response to Bronchodilator and Bronchoprovocation in Severe Asthma.

Capaldi DPI, Sheikh K, Eddy RL, Guo F, Svenningsen S, Nair P, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Acad Radiol. 2017 Oct;24(10):1268-1276. doi: 10.1016/j.acra.2017.04.012. Epub 2017 May 24.

PMID:
28551402
8.

MRI ventilation abnormalities predict quality-of-life and lung function changes in mild-to-moderate COPD: longitudinal TINCan study.

Kirby M, Eddy RL, Pike D, Svenningsen S, Coxson HO, Sin DD, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Thorax. 2017 May;72(5):475-477. doi: 10.1136/thoraxjnl-2016-209770. Epub 2017 Mar 3.

PMID:
28258250
9.

Noncystic Fibrosis Bronchiectasis: Regional Abnormalities and Response to Airway Clearance Therapy Using Pulmonary Functional Magnetic Resonance Imaging.

Svenningsen S, Guo F, McCormack DG, Parraga G.

Acad Radiol. 2017 Jan;24(1):4-12. doi: 10.1016/j.acra.2016.08.021. Epub 2016 Oct 4.

PMID:
27717759
10.

Is ventilation heterogeneity related to asthma control?

Svenningsen S, Nair P, Guo F, McCormack DG, Parraga G.

Eur Respir J. 2016 Aug;48(2):370-9. doi: 10.1183/13993003.00393-2016. Epub 2016 May 12.

11.

Regional Heterogeneity of Chronic Obstructive Pulmonary Disease Phenotypes: Pulmonary (3)He Magnetic Resonance Imaging and Computed Tomography.

Pike D, Kirby M, Eddy RL, Guo F, Capaldi DP, Ouriadov A, McCormack DG, Parraga G.

COPD. 2016 Oct;13(5):601-9. doi: 10.3109/15412555.2015.1123682. Epub 2016 Jan 20.

PMID:
26788765
12.

Ventilation Heterogeneity in Never-smokers and COPD:: Comparison of Pulmonary Functional Magnetic Resonance Imaging with the Poorly Communicating Fraction Derived From Plethysmography.

Davis C, Sheikh K, Pike D, Svenningsen S, McCormack DG, O'Donnell D, Neder JA, Parraga G; Canadian Respiratory Research Network.

Acad Radiol. 2016 Apr;23(4):398-405. doi: 10.1016/j.acra.2015.10.022. Epub 2016 Jan 8.

PMID:
26774739
13.

Pulmonary Imaging Biomarkers of Gas Trapping and Emphysema in COPD: (3)He MR Imaging and CT Parametric Response Maps.

Capaldi DP, Zha N, Guo F, Pike D, McCormack DG, Kirby M, Parraga G.

Radiology. 2016 May;279(2):597-608. doi: 10.1148/radiol.2015151484. Epub 2016 Jan 8.

PMID:
26744928
14.

Second-order Texture Measurements of (3)He Ventilation MRI: Proof-of-concept Evaluation of Asthma Bronchodilator Response.

Zha N, Pike D, Svenningsen S, Capaldi DP, McCormack DG, Parraga G.

Acad Radiol. 2016 Feb;23(2):176-85. doi: 10.1016/j.acra.2015.10.010. Epub 2015 Nov 18.

PMID:
26601971
15.

Noninvasive quantification of alveolar morphometry in elderly never- and ex-smokers.

Paulin GA, Ouriadov A, Lessard E, Sheikh K, McCormack DG, Parraga G.

Physiol Rep. 2015 Oct;3(10). pii: e12583. doi: 10.14814/phy2.12583.

16.

Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease.

Svenningsen S, Paulin GA, Sheikh K, Guo F, Hasany A, Kirby M, Rezai RE, McCormack DG, Parraga G.

COPD. 2016;13(1):66-74. doi: 10.3109/15412555.2015.1043523. Epub 2015 Oct 2.

PMID:
26430763
17.

COPD: Do Imaging Measurements of Emphysema and Airway Disease Explain Symptoms and Exercise Capacity?

Kirby M, Pike D, Sin DD, Coxson HO, McCormack DG, Parraga G.

Radiology. 2015 Dec;277(3):872-80. doi: 10.1148/radiol.2015150037. Epub 2015 Jul 7.

PMID:
26151081
18.

Ventilation heterogeneity in ex-smokers without airflow limitation.

Pike D, Kirby M, Guo F, McCormack DG, Parraga G.

Acad Radiol. 2015 Aug;22(8):1068-78. doi: 10.1016/j.acra.2015.04.006. Epub 2015 May 23.

PMID:
26008133
19.

Free-breathing pulmonary 1H and Hyperpolarized 3He MRI: comparison in COPD and bronchiectasis.

Capaldi DP, Sheikh K, Guo F, Svenningsen S, Etemad-Rezai R, Coxson HO, Leipsic JA, McCormack DG, Parraga G.

Acad Radiol. 2015 Mar;22(3):320-9. doi: 10.1016/j.acra.2014.10.003. Epub 2014 Dec 6.

PMID:
25491735
20.

Pulmonary hyperpolarized (129) Xe morphometry for mapping xenon gas concentrations and alveolar oxygen partial pressure: Proof-of-concept demonstration in healthy and COPD subjects.

Ouriadov A, Farag A, Kirby M, McCormack DG, Parraga G, Santyr GE.

Magn Reson Med. 2015 Dec;74(6):1726-32. doi: 10.1002/mrm.25550. Epub 2014 Dec 5.

PMID:
25483611
21.

Hyperpolarized 3He and 129Xe magnetic resonance imaging apparent diffusion coefficients: physiological relevance in older never- and ex-smokers.

Kirby M, Ouriadov A, Svenningsen S, Owrangi A, Wheatley A, Etemad-Rezai R, Santyr GE, McCormack DG, Parraga G.

Physiol Rep. 2014 Jul 16;2(7). pii: e12068. doi: 10.14814/phy2.12068.

22.

Pulmonary functional magnetic resonance imaging: asthma temporal-spatial maps.

Svenningsen S, Guo F, Kirby M, Choy S, Wheatley A, McCormack DG, Parraga G.

Acad Radiol. 2014 Nov;21(11):1402-10. doi: 10.1016/j.acra.2014.08.002.

PMID:
25300720
23.

Longitudinal Computed Tomography and Magnetic Resonance Imaging of COPD: Thoracic Imaging Network of Canada (TINCan) Study Objectives.

Kirby M, Pike D, McCormack DG, Lam S, Coxson HO, Parraga G.

Chronic Obstr Pulm Dis. 2014 Sep 25;1(2):200-211. doi: 10.15326/jcopdf.1.2.2014.0136.

24.

Ultra-short echo-time pulmonary MRI: evaluation and reproducibility in COPD subjects with and without bronchiectasis.

Ma W, Sheikh K, Svenningsen S, Pike D, Guo F, Etemad-Rezai R, Leipsic J, Coxson HO, McCormack DG, Parraga G.

J Magn Reson Imaging. 2015 May;41(5):1465-74. doi: 10.1002/jmri.24680. Epub 2014 Jun 26.

PMID:
24965907
25.

Hyperpolarized (3)He ventilation defects used to predict pulmonary exacerbations in mild to moderate chronic obstructive pulmonary disease.

Kirby M, Pike D, Coxson HO, McCormack DG, Parraga G.

Radiology. 2014 Dec;273(3):887-96. doi: 10.1148/radiol.14140161. Epub 2014 Jun 24.

PMID:
24960283
26.

Pulmonary abnormalities and carotid atherosclerosis in ex-smokers without airflow limitation.

Pike D, Kirby M, Lindenmaier TJ, Sheikh K, Neron CE, Hackam DG, Spence JD, Fenster A, Paterson NA, Sin DD, Coxson HO, McCormack DG, Parraga G.

COPD. 2015 Feb;12(1):62-70. doi: 10.3109/15412555.2014.908833. Epub 2014 Jun 12.

PMID:
24921977
27.

Pulmonary ventilation defects in older never-smokers.

Sheikh K, Paulin GA, Svenningsen S, Kirby M, Paterson NA, McCormack DG, Parraga G.

J Appl Physiol (1985). 2014 Aug 1;117(3):297-306. doi: 10.1152/japplphysiol.00046.2014. Epub 2014 Jun 5.

28.

What are ventilation defects in asthma?

Svenningsen S, Kirby M, Starr D, Coxson HO, Paterson NA, McCormack DG, Parraga G.

Thorax. 2014 Jan;69(1):63-71. doi: 10.1136/thoraxjnl-2013-203711. Epub 2013 Aug 16.

PMID:
23956019
29.

On the role of abnormal DL(CO) in ex-smokers without airflow limitation: symptoms, exercise capacity and hyperpolarised helium-3 MRI.

Kirby M, Owrangi A, Svenningsen S, Wheatley A, Coxson HO, Paterson NA, McCormack DG, Parraga G.

Thorax. 2013 Aug;68(8):752-9. doi: 10.1136/thoraxjnl-2012-203108. Epub 2013 Apr 19.

PMID:
23604381
30.

Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.

Svenningsen S, Kirby M, Starr D, Leary D, Wheatley A, Maksym GN, McCormack DG, Parraga G.

J Magn Reson Imaging. 2013 Dec;38(6):1521-30. doi: 10.1002/jmri.24111. Epub 2013 Apr 15.

PMID:
23589465
31.

Computed tomography density histogram analysis to evaluate pulmonary emphysema in ex-smokers.

Owrangi AM, Etemad-Rezai R, McCormack DG, Cunningham IA, Parraga G.

Acad Radiol. 2013 May;20(5):537-45. doi: 10.1016/j.acra.2012.11.010.

PMID:
23570935
32.

Lung morphometry using hyperpolarized (129) Xe apparent diffusion coefficient anisotropy in chronic obstructive pulmonary disease.

Ouriadov A, Farag A, Kirby M, McCormack DG, Parraga G, Santyr GE.

Magn Reson Med. 2013 Dec;70(6):1699-706. doi: 10.1002/mrm.24595. Epub 2013 Jan 28.

PMID:
23359386
33.

Pulmonary ventilation visualized using hyperpolarized helium-3 and xenon-129 magnetic resonance imaging: differences in COPD and relationship to emphysema.

Kirby M, Svenningsen S, Kanhere N, Owrangi A, Wheatley A, Coxson HO, Santyr GE, Paterson NA, McCormack DG, Parraga G.

J Appl Physiol (1985). 2013 Mar 15;114(6):707-15. doi: 10.1152/japplphysiol.01206.2012. Epub 2012 Dec 13.

34.

Hyperpolarized helium-3 magnetic resonance imaging of chronic obstructive pulmonary disease exacerbation.

Kirby M, Kanhere N, Etemad-Rezai R, McCormack DG, Parraga G.

J Magn Reson Imaging. 2013 May;37(5):1223-7. doi: 10.1002/jmri.23896. Epub 2012 Nov 2.

PMID:
23124806
35.

Evidence of adult lung growth in humans.

Kirby M, McCormack DG, Parraga G.

N Engl J Med. 2012 Oct 18;367(16):1566-7; author reply 1567. doi: 10.1056/NEJMc1209904. No abstract available.

36.

Hyperpolarized 3He and 129Xe MR imaging in healthy volunteers and patients with chronic obstructive pulmonary disease.

Kirby M, Svenningsen S, Owrangi A, Wheatley A, Farag A, Ouriadov A, Santyr GE, Etemad-Rezai R, Coxson HO, McCormack DG, Parraga G.

Radiology. 2012 Nov;265(2):600-10. doi: 10.1148/radiol.12120485. Epub 2012 Sep 5.

PMID:
22952383
37.

Regional pulmonary response to a methacholine challenge using hyperpolarized (3)He magnetic resonance imaging.

Costella S, Kirby M, Maksym GN, McCormack DG, Paterson NA, Parraga G.

Respirology. 2012 Nov;17(8):1237-46. doi: 10.1111/j.1440-1843.2012.02250.x.

PMID:
22889229
38.

Hyperpolarized 129Xe magnetic resonance imaging: tolerability in healthy volunteers and subjects with pulmonary disease.

Shukla Y, Wheatley A, Kirby M, Svenningsen S, Farag A, Santyr GE, Paterson NA, McCormack DG, Parraga G.

Acad Radiol. 2012 Aug;19(8):941-51. doi: 10.1016/j.acra.2012.03.018. Epub 2012 May 15.

PMID:
22591724
39.

Quantitative (1)H and hyperpolarized (3)He magnetic resonance imaging: comparison in chronic obstructive pulmonary disease and healthy never-smokers.

Owrangi AM, Wang JX, Wheatley A, McCormack DG, Parraga G.

Eur J Radiol. 2014 Jan;83(1):64-72. doi: 10.1016/j.ejrad.2012.02.018. Epub 2012 May 7.

PMID:
22571928
40.

Hyperpolarized 3He functional magnetic resonance imaging of bronchoscopic airway bypass in chronic obstructive pulmonary disease.

Mathew L, Kirby M, Farquhar D, Licskai C, Santyr G, Etemad-Rezai R, Parraga G, McCormack DG.

Can Respir J. 2012 Jan-Feb;19(1):41-3.

41.

Evaluating bronchodilator effects in chronic obstructive pulmonary disease using diffusion-weighted hyperpolarized helium-3 magnetic resonance imaging.

Kirby M, Heydarian M, Wheatley A, McCormack DG, Parraga G.

J Appl Physiol (1985). 2012 Feb;112(4):651-7. doi: 10.1152/japplphysiol.01295.2011. Epub 2011 Dec 8.

42.

Hyperpolarized 3He magnetic resonance functional imaging semiautomated segmentation.

Kirby M, Heydarian M, Svenningsen S, Wheatley A, McCormack DG, Etemad-Rezai R, Parraga G.

Acad Radiol. 2012 Feb;19(2):141-52. doi: 10.1016/j.acra.2011.10.007. Epub 2011 Nov 21.

PMID:
22104288
43.

Chronic obstructive pulmonary disease: quantification of bronchodilator effects by using hyperpolarized ³He MR imaging.

Kirby M, Mathew L, Heydarian M, Etemad-Rezai R, McCormack DG, Parraga G.

Radiology. 2011 Oct;261(1):283-92. doi: 10.1148/radiol.11110403. Epub 2011 Aug 3.

PMID:
21813741
44.

Comparison of hyperpolarized (3)He MRI with Xe-enhanced computed tomography imaging for ventilation mapping of rat lung.

Santyr GE, Couch MJ, Lam WW, Ouriadov A, Drangova M, McCormack DG, Holdsworth DW.

NMR Biomed. 2011 Nov;24(9):1073-80. doi: 10.1002/nbm.1659. Epub 2011 Jan 28.

PMID:
21274963
45.

Imaging of lung function using hyperpolarized helium-3 magnetic resonance imaging: Review of current and emerging translational methods and applications.

Fain S, Schiebler ML, McCormack DG, Parraga G.

J Magn Reson Imaging. 2010 Dec;32(6):1398-408. doi: 10.1002/jmri.22375. Review.

46.

Chronic obstructive pulmonary disease: longitudinal hyperpolarized (3)He MR imaging.

Kirby M, Mathew L, Wheatley A, Santyr GE, McCormack DG, Parraga G.

Radiology. 2010 Jul;256(1):280-9. doi: 10.1148/radiol.10091937.

PMID:
20574101
47.

Hyperpolarized (3)He magnetic resonance imaging-derived pulmonary pressure-volume curves.

Choy S, Wheatley A, McCormack DG, Parraga G.

J Appl Physiol (1985). 2010 Aug;109(2):574-85. doi: 10.1152/japplphysiol.01085.2009. Epub 2010 Jun 10.

48.

Predicting postoperative FEV1 using spiral computed tomography.

Yamashita CM, Langridge J, Hergott CA, Inculet RI, Malthaner RA, Lefcoe MS, Mehta S, Mahon JL, Lee TY, McCormack DG.

Acad Radiol. 2010 May;17(5):607-13. doi: 10.1016/j.acra.2010.01.002. Epub 2010 Feb 26.

PMID:
20188601
49.

Hyperpolarized ³He magnetic resonance imaging: preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease.

Mathew L, Kirby M, Etemad-Rezai R, Wheatley A, McCormack DG, Parraga G.

Eur J Radiol. 2011 Jul;79(1):140-6. doi: 10.1016/j.ejrad.2009.10.028. Epub 2009 Nov 22.

PMID:
19932577
50.

Hyperpolarized 3He magnetic resonance imaging of chronic obstructive pulmonary disease: reproducibility at 3.0 tesla.

Mathew L, Evans A, Ouriadov A, Etemad-Rezai R, Fogel R, Santyr G, McCormack DG, Parraga G.

Acad Radiol. 2008 Oct;15(10):1298-311. doi: 10.1016/j.acra.2008.04.019.

PMID:
18790402

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