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Items: 18


T Cell Receptor-induced Nuclear Factor κB (NF-κB) Signaling and Transcriptional Activation Are Regulated by STIM1- and Orai1-mediated Calcium Entry.

Liu X, Berry CT, Ruthel G, Madara JJ, MacGillivray K, Gray CM, Madge LA, McCorkell KA, Beiting DP, Hershberg U, May MJ, Freedman BD.

J Biol Chem. 2016 Apr 15;291(16):8440-52. doi: 10.1074/jbc.M115.713008. Epub 2016 Jan 29.


Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity.

Giacomin PR, Moy RH, Noti M, Osborne LC, Siracusa MC, Alenghat T, Liu B, McCorkell KA, Troy AE, Rak GD, Hu Y, May MJ, Ma HL, Fouser LA, Sonnenberg GF, Artis D.

J Exp Med. 2015 Sep 21;212(10):1513-28. doi: 10.1084/jem.20141831. Epub 2015 Sep 14.


NEMO-binding domain peptide inhibition of inflammatory signal-induced NF-κB activation in vivo.

McCorkell KA, May MJ.

Methods Mol Biol. 2015;1280:505-25. doi: 10.1007/978-1-4939-2422-6_30.


Noncanonical NF-κB activation and SDF-1 expression in human endothelial cells.

McCorkell KA, May MJ.

Methods Mol Biol. 2015;1280:155-80. doi: 10.1007/978-1-4939-2422-6_9.


Negative feedback regulation of NF-κB-inducing kinase is proteasome-dependent but does not require cellular inhibitors of apoptosis.

Gray CM, McCorkell KA, Chunduru SK, McKinlay MA, May MJ.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):341-6. doi: 10.1016/j.bbrc.2014.05.122. Epub 2014 Jun 2.


Noncanonical NF-κB signaling is limited by classical NF-κB activity.

Gray CM, Remouchamps C, McCorkell KA, Solt LA, Dejardin E, Orange JS, May MJ.

Sci Signal. 2014 Feb 4;7(311):ra13. doi: 10.1126/scisignal.2004557.


Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury.

Bhattacharya S, Katlinski KV, Reichert M, Takano S, Brice A, Zhao B, Yu Q, Zheng H, Carbone CJ, Katlinskaya YV, Leu NA, McCorkell KA, Srinivasan S, Girondo M, Rui H, May MJ, Avadhani NG, Rustgi AK, Fuchs SY.

EMBO Mol Med. 2014 Mar;6(3):384-97. doi: 10.1002/emmm.201303236. Epub 2014 Jan 30.


The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK.

Neely RJ, Brose MS, Gray CM, McCorkell KA, Leibowitz JM, Ma C, Rothstein JL, May MJ.

Oncogene. 2011 Jan 6;30(1):87-96. doi: 10.1038/onc.2010.396. Epub 2010 Sep 6.


Cutting edge: association with I kappa B kinase beta regulates the subcellular localization of Homer3.

Yatherajam G, Banerjee PP, McCorkell KA, Solt LA, Hanson EP, Madge LA, Kang S, Worley PF, Orange JS, May MJ.

J Immunol. 2010 Sep 1;185(5):2665-9. doi: 10.4049/jimmunol.0903488. Epub 2010 Aug 6.


Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.

Pichiorri F, Okumura H, Nakamura T, Garrison PN, Gasparini P, Suh SS, Druck T, McCorkell KA, Barnes LD, Croce CM, Huebner K.

J Biol Chem. 2009 Jan 9;284(2):1040-9. doi: 10.1074/jbc.M806638200. Epub 2008 Nov 12.


NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.

Huang GN, Huso DL, Bouyain S, Tu J, McCorkell KA, May MJ, Zhu Y, Lutz M, Collins S, Dehoff M, Kang S, Whartenby K, Powell J, Leahy D, Worley PF.

Science. 2008 Jan 25;319(5862):476-81. doi: 10.1126/science.1151227.


Influence of a nonfragile FHIT transgene on murine tumor susceptibility.

McCorkell KA, Mancini R, Siprashvili Z, Barnoski BL, Iliopoulos D, Siracusa LD, Zanesi N, Croce CM, Fong LY, Druck T, Huebner K.

Cytogenet Genome Res. 2007;118(2-4):196-203.


Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity.

Cantor JP, Iliopoulos D, Rao AS, Druck T, Semba S, Han SY, McCorkell KA, Lakshman TV, Collins JE, Wachsberger P, Friedberg JS, Huebner K.

Int J Cancer. 2007 Jan 1;120(1):24-31.


Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor.

Semba S, Han SY, Qin HR, McCorkell KA, Iliopoulos D, Pekarsky Y, Druck T, Trapasso F, Croce CM, Huebner K.

J Biol Chem. 2006 Sep 22;281(38):28244-53. Epub 2006 Jul 24.


Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential.

Semba S, Trapasso F, Fabbri M, McCorkell KA, Volinia S, Druck T, Iliopoulos D, Pekarsky Y, Ishii H, Garrison PN, Barnes LD, Croce CM, Huebner K.

Oncogene. 2006 May 11;25(20):2860-72.


Roles of FHIT and WWOX fragile genes in cancer.

Iliopoulos D, Guler G, Han SY, Druck T, Ottey M, McCorkell KA, Huebner K.

Cancer Lett. 2006 Jan 28;232(1):27-36. Epub 2005 Oct 12. Review.


Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer.

Iliopoulos D, Guler G, Han SY, Johnston D, Druck T, McCorkell KA, Palazzo J, McCue PA, Baffa R, Huebner K.

Oncogene. 2005 Feb 24;24(9):1625-33.


Fhit-deficient normal and cancer cells are mitomycin C and UVC resistant.

Ottey M, Han SY, Druck T, Barnoski BL, McCorkell KA, Croce CM, Raventos-Suarez C, Fairchild CR, Wang Y, Huebner K.

Br J Cancer. 2004 Nov 1;91(9):1669-77.

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