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Items: 1 to 50 of 151

1.

NRF2 activation with Protandim attenuates salt-induced vascular dysfunction and microvascular rarefaction.

Priestley JRC, Fink KE, McCord JM, Lombard JH.

Microcirculation. 2019 May 27:e12575. doi: 10.1111/micc.12575. [Epub ahead of print]

PMID:
31132190
2.

MiR-144 mediates Nrf2 inhibition and alveolar epithelial dysfunction in HIV-1 transgenic rats.

Kukoyi AT, Fan X, Staitieh BS, Hybertson BM, Gao B, McCord JM, Guidot DM.

Am J Physiol Cell Physiol. 2019 Aug 1;317(2):C390-C397. doi: 10.1152/ajpcell.00038.2019. Epub 2019 May 15.

PMID:
31091144
3.

Phytochemical Combination PB125 Activates the Nrf2 Pathway and Induces Cellular Protection against Oxidative Injury.

Hybertson BM, Gao B, Bose S, McCord JM.

Antioxidants (Basel). 2019 May 3;8(5). pii: E119. doi: 10.3390/antiox8050119.

4.

Hypoxia compounds exercise-induced free radical formation in humans; partitioning contributions from the cerebral and femoral circulation.

Bailey DM, Rasmussen P, Evans KA, Bohm AM, Zaar M, Nielsen HB, Brassard P, Nordsborg NB, Homann PH, Raven PB, McEneny J, Young IS, McCord JM, Secher NH.

Free Radic Biol Med. 2018 Aug 20;124:104-113. doi: 10.1016/j.freeradbiomed.2018.05.090. Epub 2018 May 31.

PMID:
29859345
5.

Protandim Protects Oligodendrocytes against an Oxidative Insult.

Lim JL, van der Pol SM, Baron W, McCord JM, de Vries HE, van Horssen J.

Antioxidants (Basel). 2016 Sep 7;5(3). pii: E30. doi: 10.3390/antiox5030030.

6.

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

Strong R, Miller RA, Antebi A, Astle CM, Bogue M, Denzel MS, Fernandez E, Flurkey K, Hamilton KL, Lamming DW, Javors MA, de Magalhães JP, Martinez PA, McCord JM, Miller BF, Müller M, Nelson JF, Ndukum J, Rainger GE, Richardson A, Sabatini DM, Salmon AB, Simpkins JW, Steegenga WT, Nadon NL, Harrison DE.

Aging Cell. 2016 Oct;15(5):872-84. doi: 10.1111/acel.12496. Epub 2016 Jun 16.

7.

Superoxide dismutases: you've come a long way, baby.

McCord JM, Fridovich I.

Antioxid Redox Signal. 2014 Apr 1;20(10):1548-9. doi: 10.1089/ars.2013.5547. Epub 2013 Sep 11. No abstract available.

PMID:
23924157
8.

The role of Nrf2 in the attenuation of cardiovascular disease.

Reuland DJ, McCord JM, Hamilton KL.

Exerc Sport Sci Rev. 2013 Jul;41(3):162-8. doi: 10.1097/JES.0b013e3182948a1e. Review.

PMID:
23558695
9.

Moral distress: levels, coping and preferred interventions in critical care and transitional care nurses.

Wilson MA, Goettemoeller DM, Bevan NA, McCord JM.

J Clin Nurs. 2013 May;22(9-10):1455-66. doi: 10.1111/jocn.12128. Epub 2013 Mar 8.

PMID:
23473022
10.

Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress.

Reuland DJ, Khademi S, Castle CJ, Irwin DC, McCord JM, Miller BF, Hamilton KL.

Free Radic Biol Med. 2013 Mar;56:102-11. doi: 10.1016/j.freeradbiomed.2012.11.016. Epub 2012 Nov 30.

PMID:
23201694
11.

Phytochemical activation of Nrf2 protects human coronary artery endothelial cells against an oxidative challenge.

Donovan EL, McCord JM, Reuland DJ, Miller BF, Hamilton KL.

Oxid Med Cell Longev. 2012;2012:132931. doi: 10.1155/2012/132931. Epub 2012 May 22.

12.

Protandim does not influence alveolar epithelial permeability or intrapulmonary oxidative stress in human subjects with alcohol use disorders.

Burnham EL, McCord JM, Bose S, Brown LA, House R, Moss M, Gaydos J.

Am J Physiol Lung Cell Mol Physiol. 2012 Apr 1;302(7):L688-99. doi: 10.1152/ajplung.00297.2011. Epub 2012 Jan 20.

13.

Potential role for elevated maternal enzymatic antioxidant status in Andean protection against altitude-associated SGA.

Julian CG, Vargas E, Browne VA, Wilson MJ, Bigham AW, Rodriguez C, McCord JM, Moore LG.

J Matern Fetal Neonatal Med. 2012 Aug;25(8):1233-40. doi: 10.3109/14767058.2011.636102. Epub 2011 Nov 30.

PMID:
22082238
14.

Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation.

Hybertson BM, Gao B, Bose SK, McCord JM.

Mol Aspects Med. 2011 Aug;32(4-6):234-46. doi: 10.1016/j.mam.2011.10.006. Epub 2011 Oct 15. Review.

15.

2',5'-Dihydroxychalcone-induced glutathione is mediated by oxidative stress and kinase signaling pathways.

Kachadourian R, Pugazhenthi S, Velmurugan K, Backos DS, Franklin CC, McCord JM, Day BJ.

Free Radic Biol Med. 2011 Sep 15;51(6):1146-54. doi: 10.1016/j.freeradbiomed.2011.05.041. Epub 2011 Jun 13.

16.

Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway.

Joddar B, Reen RK, Firstenberg MS, Varadharaj S, McCord JM, Zweier JL, Gooch KJ.

Free Radic Biol Med. 2011 Mar 15;50(6):700-9. doi: 10.1016/j.freeradbiomed.2010.12.008. Epub 2010 Dec 15.

PMID:
21167278
17.

Sustained lung activity of a novel chimeric protein, SOD2/3, after intratracheal administration.

Clarke MB, Wright R, Irwin D, Bose S, Van Rheen Z, Birari R, Stenmark KR, McCord JM, Nozik-Grayck E.

Free Radic Biol Med. 2010 Dec 15;49(12):2032-9. doi: 10.1016/j.freeradbiomed.2010.09.028. Epub 2010 Oct 4.

18.

The Dietary Supplement Protandim Decreases Plasma Osteopontin and Improves Markers of Oxidative Stress in Muscular Dystrophy Mdx Mice.

Qureshi MM, McClure WC, Arevalo NL, Rabon RE, Mohr B, Bose SK, McCord JM, Tseng BS.

J Diet Suppl. 2010 Jun 1;7(2):159-178.

19.

The chemopreventive effects of Protandim: modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis.

Robbins D, Gu X, Shi R, Liu J, Wang F, Ponville J, McCord JM, Zhao Y.

PLoS One. 2010 Jul 30;5(7):e11902. doi: 10.1371/journal.pone.0011902.

20.

Sedentary aging increases resting and exercise-induced intramuscular free radical formation.

Bailey DM, McEneny J, Mathieu-Costello O, Henry RR, James PE, McCord JM, Pietri S, Young IS, Richardson RS.

J Appl Physiol (1985). 2010 Aug;109(2):449-56. doi: 10.1152/japplphysiol.00354.2010. Epub 2010 May 27.

21.

Thiol-sensitive mutant forms of human SOD2, L60F, and I58T: the role of Cys140.

Hernandez-Saavedra D, Quijano C, Demicheli V, Souza JM, Radi R, McCord JM.

Free Radic Biol Med. 2010 May 1;48(9):1202-10. doi: 10.1016/j.freeradbiomed.2010.02.001. Epub 2010 Feb 6.

PMID:
20144705
22.

Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure.

Bogaard HJ, Natarajan R, Henderson SC, Long CS, Kraskauskas D, Smithson L, Ockaili R, McCord JM, Voelkel NF.

Circulation. 2009 Nov 17;120(20):1951-60. doi: 10.1161/CIRCULATIONAHA.109.883843. Epub 2009 Nov 2.

PMID:
19884466
23.

Increased cerebral output of free radicals during hypoxia: implications for acute mountain sickness?

Bailey DM, Taudorf S, Berg RM, Lundby C, McEneny J, Young IS, Evans KA, James PE, Shore A, Hullin DA, McCord JM, Pedersen BK, Möller K.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1283-92. doi: 10.1152/ajpregu.00366.2009. Epub 2009 Sep 2.

24.

Association of a new intronic polymorphism of the SOD2 gene (G1677T) with cancer.

Hernandez-Saavedra D, McCord JM.

Cell Biochem Funct. 2009 Jun;27(4):223-7. doi: 10.1002/cbf.1560.

PMID:
19405048
25.

Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model.

Liu J, Gu X, Robbins D, Li G, Shi R, McCord JM, Zhao Y.

PLoS One. 2009;4(4):e5284. doi: 10.1371/journal.pone.0005284. Epub 2009 Apr 22.

26.

A potential role for reactive oxygen species and the HIF-1alpha-VEGF pathway in hypoxia-induced pulmonary vascular leak.

Irwin DC, McCord JM, Nozik-Grayck E, Beckly G, Foreman B, Sullivan T, White M, T Crossno J Jr, Bailey D, Flores SC, Majka S, Klemm D, van Patot MC.

Free Radic Biol Med. 2009 Jul 1;47(1):55-61. doi: 10.1016/j.freeradbiomed.2009.03.027. Epub 2009 Apr 7.

27.

Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim.

Velmurugan K, Alam J, McCord JM, Pugazhenthi S.

Free Radic Biol Med. 2009 Feb 1;46(3):430-40. doi: 10.1016/j.freeradbiomed.2008.10.050. Epub 2008 Nov 17.

PMID:
19056485
28.

Altered free radical metabolism in acute mountain sickness: implications for dynamic cerebral autoregulation and blood-brain barrier function.

Bailey DM, Evans KA, James PE, McEneny J, Young IS, Fall L, Gutowski M, Kewley E, McCord JM, Møller K, Ainslie PN.

J Physiol. 2009 Jan 15;587(1):73-85. doi: 10.1113/jphysiol.2008.159855. Epub 2008 Oct 20.

29.

Superoxide dismutase, lipid peroxidation, and bell-shaped dose response curves.

McCord JM.

Dose Response. 2008;6(3):223-38. doi: 10.2203/dose-response.08-012.McCord. Epub 2008 Aug 6.

30.

[Evolution and free radicals. Importance of oxidative stress in human pathology].

Hernández-Saavedra D, McCord JM.

Rev Med Inst Mex Seguro Soc. 2007 Sep-Oct;45(5):477-84. Review. Spanish.

PMID:
18294439
31.

Has free radical release across the brain after carotid endarterectomy traditionally been underestimated? Significance of reperfusion hemodynamics.

Bailey DM, Morris-Stiff G, McCord JM, Lewis MH.

Stroke. 2007 Jun;38(6):1946-8. Epub 2007 Apr 26.

PMID:
17463314
32.

Electron paramagnetic spectroscopic evidence of exercise-induced free radical accumulation in human skeletal muscle.

Bailey DM, Lawrenson L, McEneny J, Young IS, James PE, Jackson SK, Henry RR, Mathieu-Costello O, McCord JM, Richardson RS.

Free Radic Res. 2007 Feb;41(2):182-90.

PMID:
17364944
33.

Vitamin C prophylaxis promotes oxidative lipid damage during surgical ischemia-reperfusion.

Bailey DM, Raman S, McEneny J, Young IS, Parham KL, Hullin DA, Davies B, McKeeman G, McCord JM, Lewis MH.

Free Radic Biol Med. 2006 Feb 15;40(4):591-600. Epub 2005 Oct 19.

PMID:
16458189
34.

Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.

Panayiotidis MI, Stabler SP, Ahmad A, Pappa A, Legros LH Jr, Hernandez-Saavedra D, Schneider BK, Allen RH, Vasiliou V, McCord JM, Kotb M, White CW.

Free Radic Biol Med. 2006 Jan 15;40(2):348-58. Epub 2005 Nov 18.

PMID:
16413417
35.

The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy.

Nelson SK, Bose SK, Grunwald GK, Myhill P, McCord JM.

Free Radic Biol Med. 2006 Jan 15;40(2):341-7.

PMID:
16413416
36.

The iron-containing superoxide dismutases of trypanosomatidae.

Turrens JF, McCord JM.

Free Radic Biol Med. 2006 Jan 15;40(2):193-5. Epub 2005 Dec 19. Review. No abstract available.

PMID:
16413401
37.

Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice.

Ling X, Cota-Gomez A, Flores NC, Hernandez-Saavedra D, McCord JM, Marecki JC, Haskins K, McDuffie M, Powers K, Kench J, Oka M, McMurtry I, Flores SC.

Free Radic Biol Med. 2005 Oct 15;39(8):1089-98.

PMID:
16198235
38.

Anti-inflammatory properties of a chimeric recombinant superoxide dismutase: SOD2/3.

Hernandez-Saavedra D, Zhou H, McCord JM.

Biomed Pharmacother. 2005 May;59(4):204-8. Epub 2005 Mar 17. Review.

PMID:
15862716
39.

Endothelial nitric oxide synthase protects the post-ischemic liver: potential interactions with superoxide.

Hines IN, Harada H, Flores S, Gao B, McCord JM, Grisham MB.

Biomed Pharmacother. 2005 May;59(4):183-9. Epub 2005 Mar 17.

PMID:
15862713
40.

Oxidative stress in organ preservation: a multifaceted approach to cardioplegia.

Nelson SK, Bose S, Rizeq M, McCord JM.

Biomed Pharmacother. 2005 May;59(4):149-57. Epub 2005 Mar 25.

PMID:
15862708
41.

SOD, oxidative stress and human pathologies: a brief history and a future vision.

McCord JM, Edeas MA.

Biomed Pharmacother. 2005 May;59(4):139-42. Epub 2005 Mar 22. Review.

PMID:
15862706
42.

Iron, free radicals, and oxidative injury.

McCord JM.

J Nutr. 2004 Nov;134(11):3171S-3172S. No abstract available.

PMID:
15514292
43.

Therapeutic control of free radicals.

McCord JM.

Drug Discov Today. 2004 Sep 15;9(18):781-2. No abstract available.

PMID:
15364063
44.

Susceptibility of murine periportal hepatocytes to hypoxia-reoxygenation: role for NO and Kupffer cell-derived oxidants.

Taniai H, Hines IN, Bharwani S, Maloney RE, Nimura Y, Gao B, Flores SC, McCord JM, Grisham MB, Aw TY.

Hepatology. 2004 Jun;39(6):1544-52.

PMID:
15185295
45.

Chimeric SOD2/3 inhibits at the endothelial-neutrophil interface to limit vascular dysfunction in ischemia-reperfusion.

Bonder CS, Knight D, Hernandez-Saavedra D, McCord JM, Kubes P.

Am J Physiol Gastrointest Liver Physiol. 2004 Sep;287(3):G676-84. Epub 2004 Apr 15.

46.

Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion.

Ng ES, Jourd'heuil D, McCord JM, Hernandez D, Yasui M, Knight D, Kubes P.

Circ Res. 2004 Mar 5;94(4):559-65. Epub 2004 Jan 22.

PMID:
14739156
47.

Synthesis and anti-inflammatory activity of a chimeric recombinant superoxide dismutase: SOD2/3.

Gao B, Flores SC, Leff JA, Bose SK, McCord JM.

Am J Physiol Lung Cell Mol Physiol. 2003 Jun;284(6):L917-25. Epub 2003 Jan 10.

49.

A novel heparin-binding, human chimeric, superoxide dismutase improves myocardial preservation and protects from ischemia-reperfusion injury.

Nelson SK, Gao B, Bose S, Rizeq M, McCord JM.

J Heart Lung Transplant. 2002 Dec;21(12):1296-303.

PMID:
12490275
50.

Regulation of postischemic liver injury following different durations of ischemia.

Hines IN, Hoffman JM, Scheerens H, Day BJ, Harada H, Pavlick KP, Bharwani S, Wolf R, Gao B, Flores S, McCord JM, Grisham MB.

Am J Physiol Gastrointest Liver Physiol. 2003 Mar;284(3):G536-45. Epub 2002 Nov 20.

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