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A comparison of three apolipoprotein B methods and their associations with incident coronary heart disease risk over a 12-year follow-up period: The Multi-Ethnic Study of Atherosclerosis.

Cao J, Steffen BT, Guan W, Remaley AT, McConnell JP, Palamalai V, Tsai MY.

J Clin Lipidol. 2018 Mar - Apr;12(2):300-304. doi: 10.1016/j.jacl.2017.12.013. Epub 2017 Dec 29.


Lipoprotein(a) Mass Levels Increase Significantly According to APOE Genotype: An Analysis of 431 239 Patients.

Moriarty PM, Varvel SA, Gordts PL, McConnell JP, Tsimikas S.

Arterioscler Thromb Vasc Biol. 2017 Mar;37(3):580-588. doi: 10.1161/ATVBAHA.116.308704. Epub 2017 Jan 5.


Prevalence of Elevated Lp(a) Mass Levels and Patient Thresholds in 532 359 Patients in the United States.

Varvel S, McConnell JP, Tsimikas S.

Arterioscler Thromb Vasc Biol. 2016 Nov;36(11):2239-2245. Epub 2016 Sep 22.


Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGA-REMODEL Randomized Clinical Trial.

Heydari B, Abdullah S, Pottala JV, Shah R, Abbasi S, Mandry D, Francis SA, Lumish H, Ghoshhajra BB, Hoffmann U, Appelbaum E, Feng JH, Blankstein R, Steigner M, McConnell JP, Harris W, Antman EM, Jerosch-Herold M, Kwong RY.

Circulation. 2016 Aug 2;134(5):378-91. doi: 10.1161/CIRCULATIONAHA.115.019949.


Lipoprotein(a) Levels Are Associated With Subclinical Calcific Aortic Valve Disease in White and Black Individuals: The Multi-Ethnic Study of Atherosclerosis.

Cao J, Steffen BT, Budoff M, Post WS, Thanassoulis G, Kestenbaum B, McConnell JP, Warnick R, Guan W, Tsai MY.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):1003-9. doi: 10.1161/ATVBAHA.115.306683. Epub 2016 Mar 3.


Comparison of cardiometabolic risk biomarkers from a national clinical laboratory with the US adult population.

Wolin E, White J, Pottala JV, Sasinowski M, Dall T, Dayspring TD, McConnell JP, Hoefner DM, Varvel SA, Thiselton DL, Warnick GR, Harris WS.

J Clin Lipidol. 2015 Nov-Dec;9(6):817-823. doi: 10.1016/j.jacl.2015.07.014. Epub 2015 Aug 8.


Biomarkers of cholesterol homeostasis in a clinical laboratory database sample comprising 667,718 patients.

Dayspring TD, Varvel SA, Ghaedi L, Thiselton DL, Bruton J, McConnell JP.

J Clin Lipidol. 2015 Nov-Dec;9(6):807-816. doi: 10.1016/j.jacl.2015.08.003. Epub 2015 Aug 29.


Discordance between apolipoprotein B and low-density lipoprotein particle number is associated with insulin resistance in clinical practice.

Varvel SA, Dayspring TD, Edmonds Y, Thiselton DL, Ghaedi L, Voros S, McConnell JP, Sasinowski M, Dall T, Warnick GR.

J Clin Lipidol. 2015 Mar-Apr;9(2):247-55. doi: 10.1016/j.jacl.2014.11.005. Epub 2014 Nov 28.


Race is a key variable in assigning lipoprotein(a) cutoff values for coronary heart disease risk assessment: the Multi-Ethnic Study of Atherosclerosis.

Guan W, Cao J, Steffen BT, Post WS, Stein JH, Tattersall MC, Kaufman JD, McConnell JP, Hoefner DM, Warnick R, Tsai MY.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):996-1001. doi: 10.1161/ATVBAHA.114.304785. Epub 2015 Feb 19.


Lipoprotein(a) mass: a massively misunderstood metric.

McConnell JP, Guadagno PA, Dayspring TD, Hoefner DM, Thiselton DL, Warnick GR, Harris WS.

J Clin Lipidol. 2014 Nov-Dec;8(6):550-3. doi: 10.1016/j.jacl.2014.08.003. Epub 2014 Aug 19. Review.


Serum α-hydroxybutyrate (α-HB) predicts elevated 1 h glucose levels and early-phase β-cell dysfunction during OGTT.

Varvel SA, Pottala JV, Thiselton DL, Caffrey R, Dall T, Sasinowski M, McConnell JP, Warnick GR, Voros S, Graham TE.

BMJ Open Diabetes Res Care. 2014 Sep 24;2(1):e000038. doi: 10.1136/bmjdrc-2014-000038. eCollection 2014.


Validation of a lipoprotein(a) particle concentration assay by quantitative lipoprotein immunofixation electrophoresis.

Guadagno PA, Summers Bellin EG, Harris WS, Dayspring TD, Hoefner DM, Thiselton DL, Stanovick B, Warnick GR, McConnell JP.

Clin Chim Acta. 2015 Jan 15;439:219-24. doi: 10.1016/j.cca.2014.10.013. Epub 2014 Oct 16.


Comprehensive biomarker testing of glycemia, insulin resistance, and beta cell function has greater sensitivity to detect diabetes risk than fasting glucose and HbA1c and is associated with improved glycemic control in clinical practice.

Varvel SA, Voros S, Thiselton DL, Pottala JV, Dall T, Warnick GR, McConnell JP, Ghaedi L, Sasinowski M, Graham T.

J Cardiovasc Transl Res. 2014 Aug;7(6):597-606. doi: 10.1007/s12265-014-9577-1. Epub 2014 Jul 29.


The current and future landscape of urinary thromboxane testing to evaluate atherothrombotic risk.

Neath SX, Jefferies JL, Berger JS, Wu AH, McConnell JP, Boone JL, McCullough PA, Jesse RL, Maisel AS.

Rev Cardiovasc Med. 2014;15(2):119-30. Review.


Does APOE genotype modify the relations between serum lipid and erythrocyte omega-3 fatty acid levels?

Harris WS, Pottala JV, Thiselton DL, A Varvel S, Baedke AM, Dayspring TD, Warnick GR, McConnell JP.

J Cardiovasc Transl Res. 2014 Jul;7(5):526-32. doi: 10.1007/s12265-014-9554-8. Epub 2014 Mar 5.


Comparative effects of an acute dose of fish oil on omega-3 fatty acid levels in red blood cells versus plasma: implications for clinical utility.

Harris WS, Varvel SA, Pottala JV, Warnick GR, McConnell JP.

J Clin Lipidol. 2013 Sep-Oct;7(5):433-40. doi: 10.1016/j.jacl.2013.05.001. Epub 2013 May 7.


In reply.

Cole TG, Contois JH, Csako G, McConnell JP, Remaley AT, Devaraj S, Hoefner DM, Mallory T, Sethi AA, Warnick GR.

Clin Chem. 2013 Aug;59(8):1277-8. No abstract available.


Myocardial tissue remodeling in adolescent obesity.

Shah RV, Abbasi SA, Neilan TG, Hulten E, Coelho-Filho O, Hoppin A, Levitsky L, de Ferranti S, Rhodes ET, Traum A, Goodman E, Feng H, Heydari B, Harris WS, Hoefner DM, McConnell JP, Seethamraju R, Rickers C, Kwong RY, Jerosch-Herold M.

J Am Heart Assoc. 2013 Aug 20;2(4):e000279. doi: 10.1161/JAHA.113.000279.


Validation of a novel homogeneous assay for of HDL3-C measurement.

Ashmaig ME, Gupta S, McConnell JP, Warnick GR.

Clin Chim Acta. 2013 Oct 21;425:37-41. doi: 10.1016/j.cca.2013.07.007. Epub 2013 Jul 24.


Association of apolipoprotein B and nuclear magnetic resonance spectroscopy-derived LDL particle number with outcomes in 25 clinical studies: assessment by the AACC Lipoprotein and Vascular Diseases Division Working Group on Best Practices.

AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices, Cole TG, Contois JH, Csako G, McConnell JP, Remaley AT, Devaraj S, Hoefner DM, Mallory T, Sethi AA, Warnick GR.

Clin Chem. 2013 May;59(5):752-70. doi: 10.1373/clinchem.2012.196733. Epub 2013 Feb 5. Erratum in: Clin Chem. 2013 Aug;59(8):1275.


Erythrocyte omega-3 fatty acids increase and linoleic acid decreases with age: observations from 160,000 patients.

Harris WS, Pottala JV, Varvel SA, Borowski JJ, Ward JN, McConnell JP.

Prostaglandins Leukot Essent Fatty Acids. 2013 Apr;88(4):257-63. doi: 10.1016/j.plefa.2012.12.004. Epub 2013 Jan 31.


Assessment of clinical performance without adequate analytical validation: A prescription for confusion.

Oliver LK, Voskoboev N, Heser D, McConnell JP, Hodel-Hanson S, Callanan H, Jaffe AS.

Clin Biochem. 2011 Oct;44(14-15):1247-52. doi: 10.1016/j.clinbiochem.2011.07.005. Epub 2011 Jul 20.


Effects on lipoprotein particles of long-term dehydroepiandrosterone in elderly men and women and testosterone in elderly men.

Srinivasan M, Irving BA, Frye RL, O'Brien P, Hartman SJ, McConnell JP, Nair KS.

J Clin Endocrinol Metab. 2010 Apr;95(4):1617-25. doi: 10.1210/jc.2009-2000. Epub 2010 Feb 5.


Hypovitaminosis D: a new risk marker for cardiovascular disease.

McConnell JP, Foley KF, Vargas GM.

Clin Lab Sci. 2009 Fall;22(4):240-6. Review. No abstract available.


Expression of lipoprotein-associated phospholipase A(2) in carotid artery plaques predicts long-term cardiac outcome.

Herrmann J, Mannheim D, Wohlert C, Versari D, Meyer FB, McConnell JP, Gössl M, Lerman LO, Lerman A.

Eur Heart J. 2009 Dec;30(23):2930-8. doi: 10.1093/eurheartj/ehp309. Epub 2009 Aug 17.


Coronary artery endothelial dysfunction is positively correlated with low density lipoprotein and inversely correlated with high density lipoprotein subclass particles measured by nuclear magnetic resonance spectroscopy.

Ford MA, McConnell JP, Lavi S, Rihal CS, Prasad A, Sandhu GS, Hartman SJ, Lerman LO, Lerman A.

Atherosclerosis. 2009 Nov;207(1):111-5. doi: 10.1016/j.atherosclerosis.2009.04.039. Epub 2009 May 6.


Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association.

Hlatky MA, Greenland P, Arnett DK, Ballantyne CM, Criqui MH, Elkind MS, Go AS, Harrell FE Jr, Hong Y, Howard BV, Howard VJ, Hsue PY, Kramer CM, McConnell JP, Normand SL, O'Donnell CJ, Smith SC Jr, Wilson PW; American Heart Association Expert Panel on Subclinical Atherosclerotic Diseases and Emerging Risk Factors and the Stroke Council.

Circulation. 2009 May 5;119(17):2408-16. doi: 10.1161/CIRCULATIONAHA.109.192278. Epub 2009 Apr 13. Erratum in: Circulation. 2009 Jun 30;119(25):e606. Hong, Yuling [added].


Apolipoprotein B and cardiovascular disease risk: position statement from the AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices.

Contois JH, McConnell JP, Sethi AA, Csako G, Devaraj S, Hoefner DM, Warnick GR; AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices.

Clin Chem. 2009 Mar;55(3):407-19. doi: 10.1373/clinchem.2008.118356. Epub 2009 Jan 23.


A patient with primary biliary cirrhosis and elevated LDL cholesterol.

Foley KF, Silveira MG, Hornseth JM, Lindor KD, McConnell JP.

Clin Chem. 2009 Jan;55(1):187-91; disscusion 191-2. doi: 10.1373/clinchem.2008.108720. No abstract available.


Effect of dehydroepiandrosterone replacement on lipoprotein profile in hypoadrenal women.

Srinivasan M, Irving BA, Dhatariya K, Klaus KA, Hartman SJ, McConnell JP, Nair KS.

J Clin Endocrinol Metab. 2009 Mar;94(3):761-4. doi: 10.1210/jc.2008-1774. Epub 2008 Dec 9.


The spin stops here: inhibition of lipoprotein-associated phospholipase A2-- a promising target but a negative initial trial?

McConnell JP, Jaffe AS.

Clin Chem. 2009 Jan;55(1):21-3. doi: 10.1373/clinchem.2008.118364. Epub 2008 Dec 1. No abstract available.


Concerns regarding lipoprotein particle measurement by ion mobility analysis.

Otvos JD, Rudel LL, McConnell JP.

Clin Chem. 2008 Dec;54(12):2086-7; author reply 2088-9. doi: 10.1373/clinchem.2008.113795. No abstract available. Erratum in: Clin Chem. 2009 Jun;55(6):1258.


Comparative analysis of fecal fat quantitation via nuclear magnetic resonance spectroscopy (1H NMR) and gravimetry.

Korpi-Steiner NL, Ward JN, Kumar V, McConnell JP.

Clin Chim Acta. 2009 Feb;400(1-2):33-6. doi: 10.1016/j.cca.2008.10.001. Epub 2008 Oct 17.


Plasma lipoprotein-associated phospholipase A2 levels in heart failure: association with mortality in the community.

Gerber Y, Dunlay SM, Jaffe AS, McConnell JP, Weston SA, Killian JM, Roger VL.

Atherosclerosis. 2009 Apr;203(2):593-8. doi: 10.1016/j.atherosclerosis.2008.07.035. Epub 2008 Aug 7.


Endurance exercise as a countermeasure for aging.

Lanza IR, Short DK, Short KR, Raghavakaimal S, Basu R, Joyner MJ, McConnell JP, Nair KS.

Diabetes. 2008 Nov;57(11):2933-42. doi: 10.2337/db08-0349. Epub 2008 Aug 20. Erratum in: Diabetes. 2012 Oct;61(10):2653.


Consensus panel recommendation for incorporating lipoprotein-associated phospholipase A2 testing into cardiovascular disease risk assessment guidelines.

Davidson MH, Corson MA, Alberts MJ, Anderson JL, Gorelick PB, Jones PH, Lerman A, McConnell JP, Weintraub HS.

Am J Cardiol. 2008 Jun 16;101(12A):51F-57F. doi: 10.1016/j.amjcard.2008.04.019. Review.


Lipoprotein-associated phospholipase A2: a risk marker or a risk factor?

Lerman A, McConnell JP.

Am J Cardiol. 2008 Jun 16;101(12A):11F-22F. doi: 10.1016/j.amjcard.2008.04.014. Review.


Role of lipoprotein-associated phospholipase A2 in atherosclerosis.

Lavi S, Herrmann J, Lavi R, McConnell JP, Lerman LO, Lerman A.

Curr Atheroscler Rep. 2008 Jun;10(3):230-5. Review.


Prosthetic systems for therapeutic optical activation and silencing of genetically-targeted neurons.

Bernstein JG, Han X, Henninger MA, Ko EY, Qian X, Franzesi GT, McConnell JP, Stern P, Desimone R, Boyden ES.

Proc SPIE Int Soc Opt Eng. 2008;6854:68540H.


Variability of lipoprotein-associated phospholipase A2 measurements.

McConnell JP, Jaffe AS.

Clin Chem. 2008 May;54(5):932-3. doi: 10.1373/clinchem.2008.103358. No abstract available.


Aspirin responsiveness in healthy volunteers measured with multiple assay platforms.

Karon BS, Wockenfus A, Scott R, Hartman SJ, McConnell JP, Santrach PJ, Jaffe AS.

Clin Chem. 2008 Jun;54(6):1060-5. doi: 10.1373/clinchem.2007.101014. Epub 2008 Apr 17.


Lipoprotein-associated phospholipase A2 predicts progression of cardiac allograft vasculopathy and increased risk of cardiovascular events in heart transplant patients.

Raichlin E, McConnell JP, Bae JH, Kremers WK, Lerman A, Frantz RP.

Transplantation. 2008 Apr 15;85(7):963-8. doi: 10.1097/TP.0b013e3181684319.


Enhanced expression of Lp-PLA2 and lysophosphatidylcholine in symptomatic carotid atherosclerotic plaques.

Mannheim D, Herrmann J, Versari D, Gössl M, Meyer FB, McConnell JP, Lerman LO, Lerman A.

Stroke. 2008 May;39(5):1448-55. doi: 10.1161/STROKEAHA.107.503193. Epub 2008 Mar 20.


Association between the paraoxonase-1 192Q>R allelic variant and coronary endothelial dysfunction in patients with early coronary artery disease.

Lavi S, McConnell JP, Lavi R, Barsness GW, Rihal CS, Novak GD, Lerman LO, Lerman A.

Mayo Clin Proc. 2008 Feb;83(2):158-64. doi: 10.4065/83.2.158.


Lack of dehydroepiandrosterone effect on a combined endurance and resistance exercise program in postmenopausal women.

Igwebuike A, Irving BA, Bigelow ML, Short KR, McConnell JP, Nair KS.

J Clin Endocrinol Metab. 2008 Feb;93(2):534-8. Epub 2007 Nov 20.


Lipoprotein-associated phospholipase A(2) : review of its role as a marker and a potential participant in coronary endothelial dysfunction.

Lavi S, Lavi R, McConnell JP, Lerman LO, Lerman A.

Mol Diagn Ther. 2007;11(4):219-26. Review.


Systemic inflammation and metabolic syndrome in cardiac allograft vasculopathy.

Raichlin ER, McConnell JP, Lerman A, Kremers WK, Edwards BS, Kushwaha SS, Clavell AL, Rodeheffer RJ, Frantz RP.

J Heart Lung Transplant. 2007 Aug;26(8):826-33.


Detectable troponin levels predict poor prognosis in patients with left ventricular dysfunction undergoing internal defibrillator implantation.

Sonel AF, Shalaby A, McConnell JP, Czarnecki T, Hogen S, Zahid M, Amidi M.

Pacing Clin Electrophysiol. 2007 Jul;30(7):839-44.


Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: association with early coronary atherosclerosis and endothelial dysfunction in humans.

Lavi S, McConnell JP, Rihal CS, Prasad A, Mathew V, Lerman LO, Lerman A.

Circulation. 2007 May 29;115(21):2715-21. Epub 2007 May 14.


Lack of an effect of pioglitazone or glipizide on lipoprotein-associated phospholipase A2 in type 2 diabetes.

Basu A, Jensen MD, McCann F, Nandy D, Mukhopadhyay D, McConnell JP, Rizza RA.

Endocr Pract. 2007 Mar-Apr;13(2):147-52.


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