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Items: 1 to 50 of 480

1.

Daily luteal serum and urinary hormone profiles in the menopause transition: Study of Women's Health Across the Nation.

Santoro N, Khoudary SRE, Nasr A, Gold EB, Greendale G, McConnell D, Neal-Perry G, Pavlovic J, Derby C, Crawford S.

Menopause. 2019 Nov 25. doi: 10.1097/GME.0000000000001453. [Epub ahead of print]

PMID:
31794501
2.

Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors.

Engelhardt H, Böse D, Petronczki M, Scharn D, Bader G, Baum A, Bergner A, Chong E, Döbel S, Egger G, Engelhardt C, Ettmayer P, Fuchs JE, Gerstberger T, Gonnella N, Grimm A, Grondal E, Haddad N, Hopfgartner B, Kousek R, Krawiec M, Kriz M, Lamarre L, Leung J, Mayer M, Patel ND, Simov BP, Reeves JT, Schnitzer R, Schrenk A, Sharps B, Solca F, Stadtmüller H, Tan Z, Wunberg T, Zoephel A, McConnell DB.

J Med Chem. 2019 Nov 27;62(22):10272-10293. doi: 10.1021/acs.jmedchem.9b01169. Epub 2019 Nov 13.

PMID:
31689114
3.

Artificial Grass as an Alternative Laneway Surface for Dairy Cows Walking to Pasture.

Buijs S, Scoley G, McConnell D.

Animals (Basel). 2019 Nov 1;9(11). pii: E891. doi: 10.3390/ani9110891.

4.

Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis.

Weinstabl H, Treu M, Rinnenthal J, Zahn SK, Ettmayer P, Bader G, Dahmann G, Kessler D, Rumpel K, Mischerikow N, Savarese F, Gerstberger T, Mayer M, Zoephel A, Schnitzer R, Sommergruber W, Martinelli P, Arnhof H, Peric-Simov B, Hofbauer KS, Garavel G, Scherbantin Y, Mitzner S, Fett TN, Scholz G, Bruchhaus J, Burkard M, Kousek R, Ciftci T, Sharps B, Schrenk A, Harrer C, Haering D, Wolkerstorfer B, Zhang X, Lv X, Du A, Li D, Li Y, Quant J, Pearson M, McConnell DB.

J Med Chem. 2019 Sep 12;62(17):7976-7997. doi: 10.1021/acs.jmedchem.9b00718. Epub 2019 Aug 14.

PMID:
31365252
5.

Drugging an undruggable pocket on KRAS.

Kessler D, Gmachl M, Mantoulidis A, Martin LJ, Zoephel A, Mayer M, Gollner A, Covini D, Fischer S, Gerstberger T, Gmaschitz T, Goodwin C, Greb P, Häring D, Hela W, Hoffmann J, Karolyi-Oezguer J, Knesl P, Kornigg S, Koegl M, Kousek R, Lamarre L, Moser F, Munico-Martinez S, Peinsipp C, Phan J, Rinnenthal J, Sai J, Salamon C, Scherbantin Y, Schipany K, Schnitzer R, Schrenk A, Sharps B, Siszler G, Sun Q, Waterson A, Wolkerstorfer B, Zeeb M, Pearson M, Fesik SW, McConnell DB.

Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):15823-15829. doi: 10.1073/pnas.1904529116. Epub 2019 Jul 22.

6.

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.

Böttcher J, Dilworth D, Reiser U, Neumüller RA, Schleicher M, Petronczki M, Zeeb M, Mischerikow N, Allali-Hassani A, Szewczyk MM, Li F, Kennedy S, Vedadi M, Barsyte-Lovejoy D, Brown PJ, Huber KVM, Rogers CM, Wells CI, Fedorov O, Rumpel K, Zoephel A, Mayer M, Wunberg T, Böse D, Zahn S, Arnhof H, Berger H, Reiser C, Hörmann A, Krammer T, Corcokovic M, Sharps B, Winkler S, Häring D, Cockcroft XL, Fuchs JE, Müllauer B, Weiss-Puxbaum A, Gerstberger T, Boehmelt G, Vakoc CR, Arrowsmith CH, Pearson M, McConnell DB.

Nat Chem Biol. 2019 Aug;15(8):822-829. doi: 10.1038/s41589-019-0310-x. Epub 2019 Jul 8.

PMID:
31285596
7.

Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.

Farnaby W, Koegl M, Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A.

Nat Chem Biol. 2019 Aug;15(8):846. doi: 10.1038/s41589-019-0329-z.

PMID:
31267096
8.

KRAS Binders Hidden in Nature.

Bergner A, Cockcroft X, Fischer G, Gollner A, Hela W, Kousek R, Mantoulidis A, Martin LJ, Mayer M, Müllauer B, Siszler G, Wolkerstorfer B, Kessler D, McConnell DB.

Chemistry. 2019 Sep 18;25(52):12037-12041. doi: 10.1002/chem.201902810. Epub 2019 Jul 25.

9.

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.

Farnaby W, Koegl M, Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A.

Nat Chem Biol. 2019 Jul;15(7):672-680. doi: 10.1038/s41589-019-0294-6. Epub 2019 Jun 10. Erratum in: Nat Chem Biol. 2019 Jul 2;:.

PMID:
31178587
10.

Potential effects of nicotine on glioblastoma and chemoradiotherapy: a review.

McConnell DD, Carr SB, Litofsky NS.

Expert Rev Neurother. 2019 Jun;19(6):545-555. doi: 10.1080/14737175.2019.1617701. Epub 2019 May 17.

PMID:
31092064
11.

CENTRAL DIABETES INSIPIDUS AND CHEMOTHERAPY: USE OF A CONTINUOUS ARGININE VASOPRESSIN INFUSION FOR FLUID AND SODIUM BALANCE.

Levine JA, Karam SL, O'Connor C, Kumar S, Soundarrajan M, McConnell D, Ammar AT, Gale AM, Zimmerman D, Szmuilowicz ED.

AACE Clin Case Rep. 2018 Nov-Dec;4(6):e487-e492. doi: 10.4158/ACCR-2018-0165.

12.

Public reason in justifications of conscientious objection in health care.

McConnell D, Card RF.

Bioethics. 2019 Jun;33(5):625-632. doi: 10.1111/bioe.12573. Epub 2019 Mar 13.

PMID:
30865301
13.

Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions.

Popow J, Arnhof H, Bader G, Berger H, Ciulli A, Covini D, Dank C, Gmaschitz T, Greb P, Karolyi-Özguer J, Koegl M, McConnell DB, Pearson M, Rieger M, Rinnenthal J, Roessler V, Schrenk A, Spina M, Steurer S, Trainor N, Traxler E, Wieshofer C, Zoephel A, Ettmayer P.

J Med Chem. 2019 Mar 14;62(5):2508-2520. doi: 10.1021/acs.jmedchem.8b01826. Epub 2019 Feb 22.

PMID:
30739444
14.

Stressors, allostatic load, and health outcomes among women hotel housekeepers: A pilot study.

Rosemberg MS, Li Y, McConnell DS, McCullagh MC, Seng JS.

J Occup Environ Hyg. 2019 Mar;16(3):206-217. doi: 10.1080/15459624.2018.1563303. Epub 2019 Feb 22.

PMID:
30615593
15.

Examining associations between action game play and motor control.

Rupp MA, McConnell DS, Smither JA.

Acta Psychol (Amst). 2019 Feb;193:55-65. doi: 10.1016/j.actpsy.2018.12.004. Epub 2018 Dec 26.

PMID:
30594040
16.

Cutaneous squamous cell carcinoma: predictors of positive and close margins and outcomes of re-excision in Northland, New Zealand.

Elliott BM, Douglass BR, McConnell D, Johnson B, Harmston C.

N Z Med J. 2018 Dec 14;131(1487):23-29.

PMID:
30543608
17.

Age at Onset of Metabolic Syndrome Among Women With and Without Polycystic Ovary Syndrome-Like Status.

Peng Q, Karvonen-Gutierrez CA, Randolph JF, Nan B, McConnell D, Harlow SD.

J Clin Endocrinol Metab. 2019 May 1;104(5):1429-1439. doi: 10.1210/jc.2018-01428.

18.

Targeted Synthesis of Complex Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-ones by Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2-p53 Inhibitors.

Gollner A, Weinstabl H, Fuchs JE, Rudolph D, Garavel G, Hofbauer KS, Karolyi-Oezguer J, Gmaschitz G, Hela W, Kerres N, Grondal E, Werni P, Ramharter J, Broeker J, McConnell DB.

ChemMedChem. 2019 Jan 8;14(1):88-93. doi: 10.1002/cmdc.201800617. Epub 2018 Dec 11.

19.

The dispersion-brightness relation for fast radio bursts from a wide-field survey.

Shannon RM, Macquart JP, Bannister KW, Ekers RD, James CW, Osłowski S, Qiu H, Sammons M, Hotan AW, Voronkov MA, Beresford RJ, Brothers M, Brown AJ, Bunton JD, Chippendale AP, Haskins C, Leach M, Marquarding M, McConnell D, Pilawa MA, Sadler EM, Troup ER, Tuthill J, Whiting MT, Allison JR, Anderson CS, Bell ME, Collier JD, Gürkan G, Heald G, Riseley CJ.

Nature. 2018 Oct;562(7727):386-390. doi: 10.1038/s41586-018-0588-y. Epub 2018 Oct 10.

PMID:
30305732
20.

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.

Hodges TR, Abbott JR, Little AJ, Sarkar D, Salovich JM, Howes JE, Akan DT, Sai J, Arnold AL, Browning C, Burns MC, Sobolik T, Sun Q, Beesetty Y, Coker JA, Scharn D, Stadtmueller H, Rossanese OW, Phan J, Waterson AG, McConnell DB, Fesik SW.

J Med Chem. 2018 Oct 11;61(19):8875-8894. doi: 10.1021/acs.jmedchem.8b01108. Epub 2018 Sep 28.

PMID:
30205005
21.

Association of Vitamin D and Parathyroid Hormone With Barrett's Esophagus.

Rubenstein JH, McConnell D, Beer DG, Chak A, Metko V, Clines G.

J Clin Gastroenterol. 2019 Nov/Dec;53(10):711-716. doi: 10.1097/MCG.0000000000001124.

PMID:
30180151
22.

Conscientious objection in healthcare: How much discretionary space best supports good medicine?

McConnell D.

Bioethics. 2019 Jan;33(1):154-161. doi: 10.1111/bioe.12477. Epub 2018 Jul 16.

PMID:
30014476
23.

Impact of Postmastectomy Radiation Therapy in Prepectoral Versus Subpectoral Implant-Based Breast Reconstruction.

Sinnott CJ, Persing SM, Pronovost M, Hodyl C, McConnell D, Ott Young A.

Ann Surg Oncol. 2018 Oct;25(10):2899-2908. doi: 10.1245/s10434-018-6602-7. Epub 2018 Jul 5.

PMID:
29978367
24.

Do Anti-Oxidants Vitamin D3, Melatonin, and Alpha-Lipoic Acid Have Synergistic Effects with Temozolomide on Cultured Glioblastoma Cells?

McConnell DD, McGreevy JW, Williams MN, Litofsky NS.

Medicines (Basel). 2018 Jun 20;5(2). pii: E58. doi: 10.3390/medicines5020058.

25.

Meningococcal Disease in Northern Ireland - Past, Present & Future: MeningoNI Forum.

Millar BC, Banks L, Bourke TW, Cunningham M, Dooley J, Elshibly S, Goldsmith CE, Fairley D, Jackson K, Lamont S, Jessop L, McCrudden E, McConnell D, McAuley K, McKenna JP, Moore P, Smithson R, Stirling J, Shields M, Moore JE.

Ulster Med J. 2018 May;87(2):83. Epub 2018 May 30.

26.

The role of individual differences on perceptions of wearable fitness device trust, usability, and motivational impact.

Rupp MA, Michaelis JR, McConnell DS, Smither JA.

Appl Ergon. 2018 Jul;70:77-87. doi: 10.1016/j.apergo.2018.02.005. Epub 2018 Feb 21.

PMID:
29866329
27.

Incidence, demographics and surgical outcomes of cutaneous squamous cell carcinoma diagnosed in Northland, New Zealand.

Elliott BM, Douglass BR, McConnell D, Johnson B, Harmston C.

N Z Med J. 2018 May 18;131(1475):61-68.

PMID:
29771903
28.

Anaemia worsens early functional outcome after traumatic brain injury: a preliminary study.

Litofsky NS, Miller DC, Chen Z, Simonyi A, Klakotskaia D, Giritharan A, Feng Q, McConnell D, Cui J, Gu Z.

Brain Inj. 2018;32(3):342-349. doi: 10.1080/02699052.2018.1425913. Epub 2018 Jan 15.

PMID:
29333886
29.

Changes in androstenedione, dehydroepiandrosterone, testosterone, estradiol, and estrone over the menopausal transition.

Kim C, Harlow SD, Zheng H, McConnell DS, Randolph JF Jr.

Womens Midlife Health. 2017;3. pii: 9. doi: 10.1186/s40695-017-0028-4. Epub 2017 Oct 17.

30.

Pentobarbital Removal During Continuous Venovenous Hemofiltration: Case Report and Review of the Literature.

Hensler DM, McConnell DP, Levasseur-Franklin KE, Greathouse KM.

J Pharm Pract. 2018 Dec;31(6):682-686. doi: 10.1177/0897190017743130. Epub 2017 Nov 21.

PMID:
29162023
31.

Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.

Kerres N, Steurer S, Schlager S, Bader G, Berger H, Caligiuri M, Dank C, Engen JR, Ettmayer P, Fischerauer B, Flotzinger G, Gerlach D, Gerstberger T, Gmaschitz T, Greb P, Han B, Heyes E, Iacob RE, Kessler D, Kölle H, Lamarre L, Lancia DR, Lucas S, Mayer M, Mayr K, Mischerikow N, Mück K, Peinsipp C, Petermann O, Reiser U, Rudolph D, Rumpel K, Salomon C, Scharn D, Schnitzer R, Schrenk A, Schweifer N, Thompson D, Traxler E, Varecka R, Voss T, Weiss-Puxbaum A, Winkler S, Zheng X, Zoephel A, Kraut N, McConnell D, Pearson M, Koegl M.

Cell Rep. 2017 Sep 19;20(12):2860-2875. doi: 10.1016/j.celrep.2017.08.081.

32.

Direct NMR Probing of Hydration Shells of Protein Ligand Interfaces and Its Application to Drug Design.

Geist L, Mayer M, Cockcroft XL, Wolkerstorfer B, Kessler D, Engelhardt H, McConnell DB, Konrat R.

J Med Chem. 2017 Nov 9;60(21):8708-8715. doi: 10.1021/acs.jmedchem.7b00845. Epub 2017 Oct 1.

PMID:
28910100
33.

Searching for Affective and Cognitive Restoration: Examining the Restorative Effects of Casual Video Game Play.

Rupp MA, Sweetman R, Sosa AE, Smither JA, McConnell DS.

Hum Factors. 2017 Nov;59(7):1096-1107. doi: 10.1177/0018720817715360. Epub 2017 Jun 21.

PMID:
28636838
34.

Determinants of social competence in pediatric brain tumor survivors who participated in an intervention study.

Barrera M, Atenafu EG, Schulte F, Bartels U, Sung L, Janzen L, Chung J, Cataudella D, Hancock K, Saleh A, Strother D, McConnell D, Downie A, Hukin J, Zelcer S.

Support Care Cancer. 2017 Sep;25(9):2891-2898. doi: 10.1007/s00520-017-3708-6. Epub 2017 Apr 14.

PMID:
28411324
35.

Parents and parenting with intellectual disabilities: An expanding field of research.

McConnell D, Feldman M, Aunos M.

J Appl Res Intellect Disabil. 2017 May;30(3):419-422. doi: 10.1111/jar.12362. No abstract available.

PMID:
28397394
36.

Menstrual Cycle Hormone Changes in Women Traversing Menopause: Study of Women's Health Across the Nation.

Santoro N, Crawford SL, El Khoudary SR, Allshouse AA, Burnett-Bowie SA, Finkelstein J, Derby C, Matthews K, Kravitz HM, Harlow SD, Greendale GA, Gold EB, Kazlauskaite R, McConnell D, Neal-Perry G, Pavlovic J, Randolph J, Weiss G, Chen HY, Lasley B.

J Clin Endocrinol Metab. 2017 Jul 1;102(7):2218-2229. doi: 10.1210/jc.2016-4017.

37.

Australian mental health consumers and carers expect more health management information from community pharmacy.

Fejzic J, Knox K, Hattingh HL, Mey A, McConnell D, Wheeler AJ.

Int J Pharm Pract. 2017 Dec;25(6):454-462. doi: 10.1111/ijpp.12356. Epub 2017 Mar 16.

PMID:
28303618
38.

Determinants of quality of life outcomes for survivors of pediatric brain tumors.

Barrera M, Atenafu EG, Schulte F, Bartels U, Sung L, Janzen L, Chung J, Cataudella D, Hancock K, Saleh A, Strother D, McConnell D, Downie A, Hukin J, Zelcer S.

Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26481. Epub 2017 Mar 10.

PMID:
28296130
39.

Love and resistance of mothers with intellectual disability from ethnocultural communities in Canada.

Pacheco L, McConnell D.

J Appl Res Intellect Disabil. 2017 May;30(3):501-510. doi: 10.1111/jar.12342. Epub 2017 Mar 1.

PMID:
28247464
40.

Improving undergraduate STEM education: The efficacy of discipline-based professional development.

Manduca CA, Iverson ER, Luxenberg M, Macdonald RH, McConnell DA, Mogk DW, Tewksbury BJ.

Sci Adv. 2017 Feb 15;3(2):e1600193. doi: 10.1126/sciadv.1600193. eCollection 2017 Feb.

41.

A randomized control intervention trial to improve social skills and quality of life in pediatric brain tumor survivors.

Barrera M, Atenafu EG, Sung L, Bartels U, Schulte F, Chung J, Cataudella D, Hancock K, Janzen L, Saleh A, Strother D, Downie A, Zelcer S, Hukin J, McConnell D.

Psychooncology. 2018 Jan;27(1):91-98. doi: 10.1002/pon.4385. Epub 2017 Feb 20.

PMID:
28124799
42.

The experience of adult children of mothers with intellectual disability: A qualitative retrospective study from Poland.

Wołowicz-Ruszkowska A, McConnell D.

J Appl Res Intellect Disabil. 2017 May;30(3):482-491. doi: 10.1111/jar.12322. Epub 2017 Jan 10.

PMID:
28070932
43.

First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease.

DeGrado TR, Kemp BJ, Pandey MK, Jiang H, Gunderson TM, Linscheid LR, Woodwick AR, McConnell DM, Fletcher JG, Johnson GB, Petersen RC, Knopman DS, Lowe VJ.

Mol Imaging. 2016 Dec 9;15. pii: 1536012116673793. Print 2016.

44.

Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 Interaction.

Gollner A, Rudolph D, Arnhof H, Bauer M, Blake SM, Boehmelt G, Cockroft XL, Dahmann G, Ettmayer P, Gerstberger T, Karolyi-Oezguer J, Kessler D, Kofink C, Ramharter J, Rinnenthal J, Savchenko A, Schnitzer R, Weinstabl H, Weyer-Czernilofsky U, Wunberg T, McConnell DB.

J Med Chem. 2016 Nov 23;59(22):10147-10162. Epub 2016 Nov 15.

PMID:
27775892
45.

Evidence of both von Willebrand factor deposition and factor V deposition onto AL amyloid as the cause of a severe bleeding diathesis.

Harrison JS, Frazier SR, McConnell DD, Yasar SJ, Melnyk N, Salaru G.

Blood Coagul Fibrinolysis. 2017 Jun;28(4):342-347. doi: 10.1097/MBC.0000000000000600.

PMID:
27676646
46.

The impact of autism services on mothers' psychological wellbeing.

Hodgetts S, McConnell D, Zwaigenbaum L, Nicholas D.

Child Care Health Dev. 2017 Jan;43(1):18-30. doi: 10.1111/cch.12398. Epub 2016 Sep 12.

PMID:
27620870
47.

Antimüllerian hormone among women with and without type 1 diabetes: the Epidemiology of Diabetes Interventions and Complications Study and the Michigan Bone Health and Metabolism Study.

Kim C, Karvonen-Gutierrez C, Kong S, Arends V, Steffes M, McConnell DS, Randolph JF Jr, Harlow SD.

Fertil Steril. 2016 Nov;106(6):1446-1452. doi: 10.1016/j.fertnstert.2016.07.009. Epub 2016 Jul 28.

48.

Characterizing the trajectories of vasomotor symptoms across the menopausal transition.

Tepper PG, Brooks MM, Randolph JF Jr, Crawford SL, El Khoudary SR, Gold EB, Lasley BL, Jones B, Joffe H, Hess R, Avis NE, Harlow S, McConnell DS, Bromberger JT, Zheng H, Ruppert K, Thurston RC.

Menopause. 2016 Oct;23(10):1067-74. doi: 10.1097/GME.0000000000000676.

49.

Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition.

Hohmann AF, Martin LJ, Minder JL, Roe JS, Shi J, Steurer S, Bader G, McConnell D, Pearson M, Gerstberger T, Gottschamel T, Thompson D, Suzuki Y, Koegl M, Vakoc CR.

Nat Chem Biol. 2016 Sep;12(9):672-9. doi: 10.1038/nchembio.2115. Epub 2016 Jul 4.

50.

Narrative self-constitution and vulnerability to co-authoring.

McConnell D.

Theor Med Bioeth. 2016 Feb;37(1):29-43. doi: 10.1007/s11017-016-9356-x.

PMID:
26983745

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