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Items: 19

1.

Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents.

Humphries PS, Bersot R, Kincaid J, Mabery E, McCluskie K, Park T, Renner T, Riegler E, Steinfeld T, Turtle ED, Wei ZL, Willis E.

Bioorg Med Chem Lett. 2018 Feb 1;28(3):293-297. doi: 10.1016/j.bmcl.2017.12.051. Epub 2017 Dec 24.

PMID:
29292223
2.

Carbazole-containing sulfonamides and sulfamides: Discovery of cryptochrome modulators as antidiabetic agents.

Humphries PS, Bersot R, Kincaid J, Mabery E, McCluskie K, Park T, Renner T, Riegler E, Steinfeld T, Turtle ED, Wei ZL, Willis E.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):757-760. doi: 10.1016/j.bmcl.2015.12.102. Epub 2015 Dec 30.

PMID:
26778255
3.

Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.

Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG.

J Biol Chem. 2007 Nov 2;282(44):31882-90. Epub 2007 Aug 31.

4.

Utility of exhaled nitric oxide as a noninvasive biomarker of lung inflammation in a disease model.

Birrell MA, McCluskie K, Hardaker E, Knowles R, Belvisi MG.

Eur Respir J. 2006 Dec;28(6):1236-44. Epub 2006 Sep 27.

5.

Phosphodiesterase type 4 inhibitors cause proinflammatory effects in vivo.

McCluskie K, Klein U, Linnevers C, Ji YH, Yang A, Husfeld C, Thomas GR.

J Pharmacol Exp Ther. 2006 Oct;319(1):468-76. Epub 2006 Jul 21.

PMID:
16861399
6.

IkappaB kinase-2-independent and -dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic.

Birrell MA, Wong S, Hardaker EL, Catley MC, McCluskie K, Collins M, Haj-Yahia S, Belvisi MG.

Mol Pharmacol. 2006 Jun;69(6):1791-800. Epub 2006 Mar 3.

PMID:
16517756
7.

Second-generation inhibitors demonstrate the involvement of p38 mitogen-activated protein kinase in post-transcriptional modulation of inflammatory mediator production in human and rodent airways.

Birrell MA, Wong S, McCluskie K, Catley MC, Hardaker EL, Haj-Yahia S, Belvisi MG.

J Pharmacol Exp Ther. 2006 Mar;316(3):1318-27. Epub 2005 Dec 20.

PMID:
16368902
8.

Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma.

Birrell MA, Hardaker E, Wong S, McCluskie K, Catley M, De Alba J, Newton R, Haj-Yahia S, Pun KT, Watts CJ, Shaw RJ, Savage TJ, Belvisi MG.

Am J Respir Crit Care Med. 2005 Oct 15;172(8):962-71. Epub 2005 Jul 7.

PMID:
16002568
9.

Steroid-resistant inflammation in a rat model of chronic obstructive pulmonary disease is associated with a lack of nuclear factor-kappaB pathway activation.

Birrell MA, Wong S, Hele DJ, McCluskie K, Hardaker E, Belvisi MG.

Am J Respir Crit Care Med. 2005 Jul 1;172(1):74-84. Epub 2005 Apr 1.

PMID:
15805185
10.

Resveratrol, an extract of red wine, inhibits lipopolysaccharide induced airway neutrophilia and inflammatory mediators through an NF-kappaB-independent mechanism.

Birrell MA, McCluskie K, Wong S, Donnelly LE, Barnes PJ, Belvisi MG.

FASEB J. 2005 May;19(7):840-1. Epub 2005 Feb 25.

PMID:
15734790
11.

PPAR-gamma agonists as therapy for diseases involving airway neutrophilia.

Birrell MA, Patel HJ, McCluskie K, Wong S, Leonard T, Yacoub MH, Belvisi MG.

Eur Respir J. 2004 Jul;24(1):18-23.

12.

Nitric oxide as a noninvasive biomarker of lipopolysaccharide-induced airway inflammation: possible role in lung neutrophilia.

McCluskie K, Birrell MA, Wong S, Belvisi MG.

J Pharmacol Exp Ther. 2004 Nov;311(2):625-33. Epub 2004 Jun 29.

PMID:
15226380
13.

Dissociation by steroids of eosinophilic inflammation from airway hyperresponsiveness in murine airways.

Birrell MA, Battram CH, Woodman P, McCluskie K, Belvisi MG.

Respir Res. 2003;4:3. Epub 2003 Mar 21.

14.

Pharmacological assessment of the nitric-oxide synthase isoform involved in eosinophilic inflammation in a rat model of sephadex-induced airway inflammation.

Birrell MA, McCluskie K, Haddad el-B, Battram CH, Webber SE, Foster ML, Yacoub MH, Belvisi MG.

J Pharmacol Exp Ther. 2003 Mar;304(3):1285-91.

PMID:
12604708
15.

Functional characterization and biomarker identification in the Brown Norway model of allergic airway inflammation.

Underwood SL, Haddad el-B, Birrell MA, McCluskie K, Pecoraro M, Dabrowski D, Webber SE, Foster ML, Belvisi MG.

Br J Pharmacol. 2002 Sep;137(2):263-75.

16.

Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation.

Haddad el-B, McCluskie K, Birrell MA, Dabrowski D, Pecoraro M, Underwood S, Chen B, De Sanctis GT, Webber SE, Foster ML, Belvisi MG.

J Immunol. 2002 Jul 15;169(2):974-82.

17.

Critical role for T cells in Sephadex-induced airway inflammation: pharmacological and immunological characterization and molecular biomarker identification.

Haddad el-B, Underwood SL, Dabrowski D, Birrell MA, McCluskie K, Battram CH, Pecoraro M, Foster ML, Belvisi MG.

J Immunol. 2002 Mar 15;168(6):3004-16.

18.

Role of p38 MAP kinase in LPS-induced airway inflammation in the rat.

Haddad EB, Birrell M, McCluskie K, Ling A, Webber SE, Foster ML, Belvisi MG.

Br J Pharmacol. 2001 Apr;132(8):1715-24.

19.

Effect of the p38 kinase inhibitor, SB 203580, on sephadex induced airway inflammation in the rat.

Birrell M, Hele D, McCluskie K, Webber S, Foster M, Belvisi MG.

Eur Respir J. 2000 Nov;16(5):947-50.

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