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Items: 1 to 50 of 269

1.

Discovery of 4,6-bis(2-((E)-benzylidene)hydrazinyl)pyrimidin-2-Amine with Antibiotic Activity.

Russell CC, Stevens A, Young KA, Baker JR, McCluskey SN, Khazandi M, Pi H, Ogunniyi A, Page SW, Trott DJ, McCluskey A.

ChemistryOpen. 2019 Jul 4;8(7):896-907. doi: 10.1002/open.201800241. eCollection 2019 Jul.

2.

Dosage and predictors of arm practice during inpatient stroke rehabilitation: an inception cohort study.

Vratsistas-Curto A, Sherrington C, McCluskey A.

Disabil Rehabil. 2019 Jul 16:1-8. doi: 10.1080/09638288.2019.1635215. [Epub ahead of print]

PMID:
31311348
3.

An introduction to classical molecular dynamics simulation for experimental scattering users.

McCluskey AR, Grant J, Symington AR, Snow T, Doutch J, Morgan BJ, Parker SC, Edler KJ.

J Appl Crystallogr. 2019 May 7;52(Pt 3):665-668. doi: 10.1107/S1600576719004333. eCollection 2019 Jun 1.

4.

In vitro Antimicrobial Activity of Robenidine, Ethylenediaminetetraacetic Acid and Polymyxin B Nonapeptide Against Important Human and Veterinary Pathogens.

Khazandi M, Pi H, Chan WY, Ogunniyi AD, Sim JXF, Venter H, Garg S, Page SW, Hill PB, McCluskey A, Trott DJ.

Front Microbiol. 2019 Apr 25;10:837. doi: 10.3389/fmicb.2019.00837. eCollection 2019.

5.

Aminoguanidines: New leads for treatment of Giardia duodenalis infection.

Abraham RJ, Abraham S, Stevens AJ, Page SW, McCluskey A, Trott DJ, O'Handley RM.

Int J Parasitol Drugs Drug Resist. 2019 Apr 8;10:38-44. doi: 10.1016/j.ijpddr.2019.04.003. [Epub ahead of print]

6.

Mechanisms of tethering and cargo transfer during epididymosome-sperm interactions.

Zhou W, Stanger SJ, Anderson AL, Bernstein IR, De Iuliis GN, McCluskey A, McLaughlin EA, Dun MD, Nixon B.

BMC Biol. 2019 Apr 18;17(1):35. doi: 10.1186/s12915-019-0653-5.

7.

Development of a participatory, tailored behaviour change intervention to increase active practice during inpatient stroke rehabilitation.

Stewart C, Power E, McCluskey A, Kuys S.

Disabil Rehabil. 2019 Apr 14:1-9. doi: 10.1080/09638288.2019.1597178. [Epub ahead of print]

PMID:
30982361
8.

Synthesis and Cytotoxicity of Octahydroepoxyisoindole-7-carboxylic Acids and Norcantharidin-Amide Hybrids as Norcantharidin Analogues.

Hizartzidis L, Gilbert J, Gordon CP, Sakoff JA, McCluskey A.

ChemMedChem. 2019 Jun 18;14(12):1152-1161. doi: 10.1002/cmdc.201900180. Epub 2019 May 14.

PMID:
30938091
9.

Targeting Glioma Stem Cells by Functional Inhibition of Dynamin 2: A Novel Treatment Strategy for Glioblastoma.

Luwor R, Morokoff AP, Amiridis S, D'Abaco G, Paradiso L, Stylli SS, Nguyen HPT, Tarleton M, Young KA, O'Brien TJ, Robinson PJ, Chircop M, McCluskey A, Jones NC.

Cancer Invest. 2019;37(3):144-155. doi: 10.1080/07357907.2019.1582060. Epub 2019 Mar 25.

PMID:
30907150
10.

Developing interventions to address sexuality after stroke: Findings from a four-panel modified Delphi study.

McGrath M, Lever S, McCluskey A, Power E.

J Rehabil Med. 2019 May 13;51(5):352-360. doi: 10.2340/16501977-2548.

11.

Bayesian determination of the effect of a deep eutectic solvent on the structure of lipid monolayers.

McCluskey AR, Sanchez-Fernandez A, Edler KJ, Parker SC, Jackson AJ, Campbell RA, Arnold T.

Phys Chem Chem Phys. 2019 Mar 13;21(11):6133-6141. doi: 10.1039/c9cp00203k.

PMID:
30816891
12.

Constraint-induced movement therapy for upper limb recovery in adult neurorehabilitation: An international survey of current knowledge and experience.

Christie LJ, McCluskey A, Lovarini M.

Aust Occup Ther J. 2019 Jun;66(3):401-412. doi: 10.1111/1440-1630.12567. Epub 2019 Feb 4.

PMID:
30714621
13.

The Bispidinone Derivative 3,7-Bis-[2-(S)-amino-3-(1H-indol-3-yl)-propionyl]-1,5-diphenyl-3,7-diazabicyclo[3.3.1]nonan-9-one Dihydrochloride Induces an Apoptosis-Mediated Cytotoxic Effect on Pancreatic Cancer Cells In Vitro.

Predebon MJ, Bond DR, Brzozowski J, Jankowski H, Deane F, Tarleton M, Shaw AA, McCluskey A, Bowyer MC, Weidenhofer J, Scarlett CJ.

Molecules. 2019 Jan 31;24(3). pii: E524. doi: 10.3390/molecules24030524.

14.

Attributes of evidence-based occupational therapists in stroke rehabilitation.

Hallé MC, Mylopoulos M, Rochette A, Vachon B, Menon A, McCluskey A, Amari F, Thomas A.

Can J Occup Ther. 2018 Dec;85(5):351-364. doi: 10.1177/0008417418802600. Epub 2018 Nov 19.

PMID:
30453765
15.

Gram-Positive and Gram-Negative Antibiotic Activity of Asymmetric and Monomeric Robenidine Analogues.

Russell CC, Stevens A, Pi H, Khazandi M, Ogunniyi AD, Young KA, Baker JR, McCluskey SN, Page SW, Trott DJ, McCluskey A.

ChemMedChem. 2018 Dec 6;13(23):2573-2580. doi: 10.1002/cmdc.201800463. Epub 2018 Nov 19.

PMID:
30318716
16.

How is sexuality after stroke experienced by stroke survivors and partners of stroke survivors? A systematic review of qualitative studies.

McGrath M, Lever S, McCluskey A, Power E.

Clin Rehabil. 2019 Feb;33(2):293-303. doi: 10.1177/0269215518793483. Epub 2018 Sep 5.

PMID:
30180769
17.

Small-Molecule Inhibitors of the NusB-NusE Protein-Protein Interaction with Antibiotic Activity.

Cossar PJ, Abdel-Hamid MK, Ma C, Sakoff JA, Trinh TN, Gordon CP, Lewis PJ, McCluskey A.

ACS Omega. 2017 Jul 31;2(7):3839-3857. doi: 10.1021/acsomega.7b00273. Epub 2017 Jul 25.

18.

FD5180, a Novel Protein Kinase Affinity Probe, and the Effect of Bead Loading on Protein Kinase Identification.

Deane FM, Lin AJS, Hains PG, Pilgrim SL, Robinson PJ, McCluskey A.

ACS Omega. 2017 Jul 31;2(7):3828-3838. doi: 10.1021/acsomega.7b00020. Epub 2017 Jul 25.

19.

Protein-protein interactions as antibiotic targets: A medicinal chemistry perspective.

Cossar PJ, Lewis PJ, McCluskey A.

Med Res Rev. 2018 Jul 13. doi: 10.1002/med.21519. [Epub ahead of print] Review.

PMID:
30004586
20.

The crystal structures of 3-O-benzyl-1,2-O-iso-propyl-idene-5-O-methane-sulfonyl-6-O-tri-phenyl-methyl-α-d-gluco-furan-ose and its azide displacement product.

Clarke Z, Barnes E, Prichard KL, Mares LJ, Clegg JK, McCluskey A, Houston TA, Simone MI.

Acta Crystallogr E Crystallogr Commun. 2018 May 31;74(Pt 6):862-867. doi: 10.1107/S205698901800765X. eCollection 2018 Jun 1.

21.

Previous experience and walking capacity predict community outings after stroke: An observational study.

Karageorge A DCP, Vargas J BPhty, Ada L PhD, Kelly PJ PhD, McCluskey A PhD.

Physiother Theory Pract. 2018 Jun 14:1-6. doi: 10.1080/09593985.2018.1484829. [Epub ahead of print]

PMID:
29902102
22.

Responsiveness of five measures of arm function in acute stroke rehabilitation.

Vratsistas-Curto A, Sherrington C, McCluskey A.

Clin Rehabil. 2018 Aug;32(8):1098-1107. doi: 10.1177/0269215518778316. Epub 2018 May 30.

PMID:
29843521
23.

Dichlorophenylacrylonitriles as AhR Ligands That Display Selective Breast Cancer Cytotoxicity in vitro.

Baker JR, Gilbert J, Paula S, Zhu X, Sakoff JA, McCluskey A.

ChemMedChem. 2018 Jul 18;13(14):1447-1458. doi: 10.1002/cmdc.201800256. Epub 2018 Jul 2.

PMID:
29771007
24.

In situ epoxide generation by dimethyldioxirane oxidation and the use of epichlorohydrin in the flow synthesis of a library of β-amino alcohols.

Cossar PJ, Baker JR, Cain N, McCluskey A.

R Soc Open Sci. 2018 Apr 4;5(4):171190. doi: 10.1098/rsos.171190. eCollection 2018 Apr.

25.

A focused library synthesis and cytotoxicity of quinones derived from the natural product bolinaquinone.

Ghods A, Gilbert J, Baker JR, Russell CC, Sakoff JA, McCluskey A.

R Soc Open Sci. 2018 Apr 4;5(4):171189. doi: 10.1098/rsos.171189. eCollection 2018 Apr.

26.

Patient and therapist experiences of using affordable feedback-based technology in rehabilitation: a qualitative study nested in a randomized controlled trial.

Hamilton C, McCluskey A, Hassett L, Killington M, Lovarini M.

Clin Rehabil. 2018 Sep;32(9):1258-1270. doi: 10.1177/0269215518771820. Epub 2018 Apr 26.

PMID:
29696990
27.

Experiences of therapists using feedback-based technology to improve physical function in rehabilitation settings: a qualitative systematic review.

Hamilton C, Lovarini M, McCluskey A, Folly de Campos T, Hassett L.

Disabil Rehabil. 2019 Jul;41(15):1739-1750. doi: 10.1080/09638288.2018.1446187. Epub 2018 Mar 7.

PMID:
29513052
28.

Use of audit, feedback and education increased guideline implementation in a multidisciplinary stroke unit.

Vratsistas-Curto A, McCluskey A, Schurr K.

BMJ Open Qual. 2017 Nov 6;6(2):e000212. doi: 10.1136/bmjoq-2017-000212. eCollection 2017.

29.

(Z)-2-(3,4-Dichlorophenyl)-3-(1H-Pyrrol-2-yl)Acrylonitrile Exhibits Selective Antitumor Activity in Breast Cancer Cell Lines via the Aryl Hydrocarbon Receptor Pathway.

Gilbert J, De Iuliis GN, Tarleton M, McCluskey A, Sakoff JA.

Mol Pharmacol. 2018 Feb;93(2):168-177. doi: 10.1124/mol.117.109827. Epub 2017 Dec 21.

PMID:
29269419
30.

Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis.

Zhou W, Anderson AL, Turner AP, De Iuliis GN, McCluskey A, McLaughlin EA, Nixon B.

Mol Hum Reprod. 2017 Oct 1;23(10):657-673. doi: 10.1093/molehr/gax044.

PMID:
29044420
31.

Back to (non-)Basics: An Update on Neutral and Charge-Balanced Glycosidase Inhibitors.

Simone MI, Mares LJ, Eveleens CA, McCluskey A, Pappin BB, Kiefel MJ, Houston TA.

Mini Rev Med Chem. 2018;18(10):812-827. doi: 10.2174/1389557517666171002161325. Review.

PMID:
28969552
32.

Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent.

Ogunniyi AD, Khazandi M, Stevens AJ, Sims SK, Page SW, Garg S, Venter H, Powell A, White K, Petrovski KR, Laven-Law G, Tótoli EG, Salgado HR, Pi H, Coombs GW, Shinabarger DL, Turnidge JD, Paton JC, McCluskey A, Trott DJ.

PLoS One. 2017 Sep 5;12(9):e0183457. doi: 10.1371/journal.pone.0183457. eCollection 2017.

33.

Lysosomotropism depends on glucose: a chloroquine resistance mechanism.

Gallagher LE, Radhi OA, Abdullah MO, McCluskey AG, Boyd M, Chan EYW.

Cell Death Dis. 2017 Aug 24;8(8):e3014. doi: 10.1038/cddis.2017.416.

34.

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief.

Jensen DD, Lieu T, Halls ML, Veldhuis NA, Imlach WL, Mai QN, Poole DP, Quach T, Aurelio L, Conner J, Herenbrink CK, Barlow N, Simpson JS, Scanlon MJ, Graham B, McCluskey A, Robinson PJ, Escriou V, Nassini R, Materazzi S, Geppetti P, Hicks GA, Christie MJ, Porter CJH, Canals M, Bunnett NW.

Sci Transl Med. 2017 May 31;9(392). pii: eaal3447. doi: 10.1126/scitranslmed.aal3447.

35.

Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis.

Zhou W, De Iuliis GN, Turner AP, Reid AT, Anderson AL, McCluskey A, McLaughlin EA, Nixon B.

Biol Reprod. 2017 Jan 1;96(1):159-173. doi: 10.1095/biolreprod.116.145433.

PMID:
28395327
36.

HIV infection is influenced by dynamin at 3 independent points in the viral life cycle.

Aggarwal A, Hitchen TL, Ootes L, McAllery S, Wong A, Nguyen K, McCluskey A, Robinson PJ, Turville SG.

Traffic. 2017 Jun;18(6):392-410. doi: 10.1111/tra.12481. Epub 2017 Apr 11.

37.

Small molecule Hedgehog pathway antagonists.

Trinh TN, McLaughlin EA, Gordon CP, Bernstein IR, Pye VJ, Redgrove KA, McCluskey A.

Org Biomol Chem. 2017 Apr 5;15(14):3046-3059. doi: 10.1039/c6ob01959e.

PMID:
28318003
38.

Targeted delivery of an ADP-ribosylating bacterial toxin into cancer cells.

Zahaf NI, Lang AE, Kaiser L, Fichter CD, Lassmann S, McCluskey A, Augspach A, Aktories K, Schmidt G.

Sci Rep. 2017 Jan 27;7:41252. doi: 10.1038/srep41252.

39.

Structure and feasibility of extra practice during stroke rehabilitation: A systematic scoping review.

Stewart C, McCluskey A, Ada L, Kuys S.

Aust Occup Ther J. 2017 Jun;64(3):204-217. doi: 10.1111/1440-1630.12351. Epub 2017 Jan 10. Review.

PMID:
28071808
40.

Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.

Odell LR, Abdel-Hamid MK, Hill TA, Chau N, Young KA, Deane FM, Sakoff JA, Andersson S, Daniel JA, Robinson PJ, McCluskey A.

J Med Chem. 2017 Jan 12;60(1):349-361. doi: 10.1021/acs.jmedchem.6b01422. Epub 2016 Dec 20.

PMID:
27997171
41.

Identification and validation of small molecule modulators of the NusB-NusE interaction.

Cossar PJ, Ma C, Gordon CP, Ambrus JI, Lewis PJ, McCluskey A.

Bioorg Med Chem Lett. 2017 Jan 15;27(2):162-167. doi: 10.1016/j.bmcl.2016.11.091. Epub 2016 Dec 1.

PMID:
27964882
42.

Cytotoxicity of a Series of Norcantharidin-Inspired Tetrahydroepoxyisoindole Carboxamides.

Spare LK, Falsetta P, Gilbert J, Harman DG, Baker MA, Li F, McCluskey A, Clegg JK, Sakoff JA, Aldrich-Wright JR, Gordon CP.

ChemMedChem. 2017 Jan 20;12(2):130-145. doi: 10.1002/cmdc.201600573. Epub 2017 Jan 3.

PMID:
27921386
43.

5-Aryl-2-(naphtha-1-yl)sulfonamido-thiazol-4(5H)-ones as clathrin inhibitors.

Robertson MJ, Horatscheck A, Sauer S, von Kleist L, Baker JR, Stahlschmidt W, Nazaré M, Whiting A, Chau N, Robinson PJ, Haucke V, McCluskey A.

Org Biomol Chem. 2016 Nov 29;14(47):11266-11278.

PMID:
27853797
44.

Validity, reliability and ease of use of the disabilities of arm, shoulder and hand questionnaire in adults following stroke.

Dalton E, Lannin NA, Laver K, Ross L, Ashford S, McCluskey A, Cusick A.

Disabil Rehabil. 2017 Dec;39(24):2504-2511. doi: 10.1080/09638288.2016.1229364. Epub 2016 Oct 21.

PMID:
27767374
45.

Dynamin 2 is essential for mammalian spermatogenesis.

Redgrove KA, Bernstein IR, Pye VJ, Mihalas BP, Sutherland JM, Nixon B, McCluskey A, Robinson PJ, Holt JE, McLaughlin EA.

Sci Rep. 2016 Oct 11;6:35084. doi: 10.1038/srep35084.

46.

Recapping CAPs: The past 13 years of Critically Appraised Papers.

Cordier R, McCluskey A.

Aust Occup Ther J. 2016 Oct;63(5):357-358. doi: 10.1111/1440-1630.12329. No abstract available.

PMID:
27714865
47.

A facile hybrid 'flow and batch' access to substituted 3,4-dihydro-2H-benzo[b][1,4]oxazinones.

Lin AJ, Russell CC, Baker JR, Frailey SL, Sakoff JA, McCluskey A.

Org Biomol Chem. 2016 Sep 21;14(37):8732-8742.

PMID:
27714138
48.

Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors.

Trinh TN, McLaughlin EA, Abdel-Hamid MK, Gordon CP, Bernstein IR, Pye V, Cossar P, Sakoff JA, McCluskey A.

Org Biomol Chem. 2016 Jul 14;14(26):6304-15. doi: 10.1039/c6ob00606j. Epub 2016 Jun 7.

PMID:
27272335
49.

Effect of affordable technology on physical activity levels and mobility outcomes in rehabilitation: a protocol for the Activity and MObility UsiNg Technology (AMOUNT) rehabilitation trial.

Hassett L, van den Berg M, Lindley RI, Crotty M, McCluskey A, van der Ploeg HP, Smith ST, Schurr K, Killington M, Bongers B, Howard K, Heritier S, Togher L, Hackett M, Treacy D, Dorsch S, Wong S, Scrivener K, Chagpar S, Weber H, Pearson R, Sherrington C.

BMJ Open. 2016 Jun 6;6(6):e012074. doi: 10.1136/bmjopen-2016-012074.

50.

Older adults experience difficulty completing the lines and dots tasks of the Motor Assessment Scale.

Dettrick-Janes M, McCluskey A, Lannin NA, Scanlan JN.

Scand J Occup Ther. 2017 Sep;24(5):320-328. doi: 10.1080/11038128.2016.1187202. Epub 2016 May 26.

PMID:
27228182

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