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Items: 1 to 50 of 251

1.

Protein-protein interactions as antibiotic targets: A medicinal chemistry perspective.

Cossar PJ, Lewis PJ, McCluskey A.

Med Res Rev. 2018 Jul 13. doi: 10.1002/med.21519. [Epub ahead of print] Review.

PMID:
30004586
2.

The crystal structures of 3-O-benzyl-1,2-O-iso-propyl-idene-5-O-methane-sulfonyl-6-O-tri-phenyl-methyl-α-d-gluco-furan-ose and its azide displacement product.

Clarke Z, Barnes E, Prichard KL, Mares LJ, Clegg JK, McCluskey A, Houston TA, Simone MI.

Acta Crystallogr E Crystallogr Commun. 2018 May 31;74(Pt 6):862-867. doi: 10.1107/S205698901800765X. eCollection 2018 Jun 1.

3.

Previous experience and walking capacity predict community outings after stroke: An observational study.

Karageorge A DCP, Vargas J BPhty, Ada L PhD, Kelly PJ PhD, McCluskey A PhD.

Physiother Theory Pract. 2018 Jun 14:1-6. doi: 10.1080/09593985.2018.1484829. [Epub ahead of print]

PMID:
29902102
4.

Responsiveness of five measures of arm function in acute stroke rehabilitation.

Vratsistas-Curto A, Sherrington C, McCluskey A.

Clin Rehabil. 2018 May 1:269215518778316. doi: 10.1177/0269215518778316. [Epub ahead of print]

PMID:
29843521
5.

Dichlorophenylacrylonitriles as AhR Ligands That Display Selective Breast Cancer Cytotoxicity in vitro.

Baker JR, Gilbert J, Paula S, Zhu X, Sakoff JA, McCluskey A.

ChemMedChem. 2018 May 17. doi: 10.1002/cmdc.201800256. [Epub ahead of print]

PMID:
29771007
6.

In situ epoxide generation by dimethyldioxirane oxidation and the use of epichlorohydrin in the flow synthesis of a library of β-amino alcohols.

Cossar PJ, Baker JR, Cain N, McCluskey A.

R Soc Open Sci. 2018 Apr 4;5(4):171190. doi: 10.1098/rsos.171190. eCollection 2018 Apr.

7.

A focused library synthesis and cytotoxicity of quinones derived from the natural product bolinaquinone.

Ghods A, Gilbert J, Baker JR, Russell CC, Sakoff JA, McCluskey A.

R Soc Open Sci. 2018 Apr 4;5(4):171189. doi: 10.1098/rsos.171189. eCollection 2018 Apr.

8.

Patient and therapist experiences of using affordable feedback-based technology in rehabilitation: a qualitative study nested in a randomized controlled trial.

Hamilton C, McCluskey A, Hassett L, Killington M, Lovarini M.

Clin Rehabil. 2018 Apr 1:269215518771820. doi: 10.1177/0269215518771820. [Epub ahead of print]

PMID:
29696990
9.

Experiences of therapists using feedback-based technology to improve physical function in rehabilitation settings: a qualitative systematic review.

Hamilton C, Lovarini M, McCluskey A, Folly de Campos T, Hassett L.

Disabil Rehabil. 2018 Mar 7:1-12. doi: 10.1080/09638288.2018.1446187. [Epub ahead of print]

PMID:
29513052
10.

Use of audit, feedback and education increased guideline implementation in a multidisciplinary stroke unit.

Vratsistas-Curto A, McCluskey A, Schurr K.

BMJ Open Qual. 2017 Nov 6;6(2):e000212. doi: 10.1136/bmjoq-2017-000212. eCollection 2017.

11.

(Z)-2-(3,4-Dichlorophenyl)-3-(1H-Pyrrol-2-yl)Acrylonitrile Exhibits Selective Antitumor Activity in Breast Cancer Cell Lines via the Aryl Hydrocarbon Receptor Pathway.

Gilbert J, De Iuliis GN, Tarleton M, McCluskey A, Sakoff JA.

Mol Pharmacol. 2018 Feb;93(2):168-177. doi: 10.1124/mol.117.109827. Epub 2017 Dec 21.

PMID:
29269419
12.

Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis.

Zhou W, Anderson AL, Turner AP, De Iuliis GN, McCluskey A, McLaughlin EA, Nixon B.

Mol Hum Reprod. 2017 Oct 1;23(10):657-673. doi: 10.1093/molehr/gax044.

PMID:
29044420
13.

Back to (non-)Basics: An Update on Neutral and Charge-Balanced Glycosidase Inhibitors.

Simone MI, Mares LJ, Eveleens CA, McCluskey A, Pappin BB, Kiefel MJ, Houston TA.

Mini Rev Med Chem. 2018;18(10):812-827. doi: 10.2174/1389557517666171002161325. Review.

PMID:
28969552
14.

Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent.

Ogunniyi AD, Khazandi M, Stevens AJ, Sims SK, Page SW, Garg S, Venter H, Powell A, White K, Petrovski KR, Laven-Law G, Tótoli EG, Salgado HR, Pi H, Coombs GW, Shinabarger DL, Turnidge JD, Paton JC, McCluskey A, Trott DJ.

PLoS One. 2017 Sep 5;12(9):e0183457. doi: 10.1371/journal.pone.0183457. eCollection 2017.

15.

Lysosomotropism depends on glucose: a chloroquine resistance mechanism.

Gallagher LE, Radhi OA, Abdullah MO, McCluskey AG, Boyd M, Chan EYW.

Cell Death Dis. 2017 Aug 24;8(8):e3014. doi: 10.1038/cddis.2017.416.

16.

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief.

Jensen DD, Lieu T, Halls ML, Veldhuis NA, Imlach WL, Mai QN, Poole DP, Quach T, Aurelio L, Conner J, Herenbrink CK, Barlow N, Simpson JS, Scanlon MJ, Graham B, McCluskey A, Robinson PJ, Escriou V, Nassini R, Materazzi S, Geppetti P, Hicks GA, Christie MJ, Porter CJH, Canals M, Bunnett NW.

Sci Transl Med. 2017 May 31;9(392). pii: eaal3447. doi: 10.1126/scitranslmed.aal3447.

17.

Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis.

Zhou W, De Iuliis GN, Turner AP, Reid AT, Anderson AL, McCluskey A, McLaughlin EA, Nixon B.

Biol Reprod. 2017 Jan 1;96(1):159-173. doi: 10.1095/biolreprod.116.145433.

PMID:
28395327
18.

HIV infection is influenced by dynamin at 3 independent points in the viral life cycle.

Aggarwal A, Hitchen TL, Ootes L, McAllery S, Wong A, Nguyen K, McCluskey A, Robinson PJ, Turville SG.

Traffic. 2017 Jun;18(6):392-410. doi: 10.1111/tra.12481. Epub 2017 Apr 11.

19.

Small molecule Hedgehog pathway antagonists.

Trinh TN, McLaughlin EA, Gordon CP, Bernstein IR, Pye VJ, Redgrove KA, McCluskey A.

Org Biomol Chem. 2017 Apr 5;15(14):3046-3059. doi: 10.1039/c6ob01959e.

PMID:
28318003
20.

Targeted delivery of an ADP-ribosylating bacterial toxin into cancer cells.

Zahaf NI, Lang AE, Kaiser L, Fichter CD, Lassmann S, McCluskey A, Augspach A, Aktories K, Schmidt G.

Sci Rep. 2017 Jan 27;7:41252. doi: 10.1038/srep41252.

21.

Structure and feasibility of extra practice during stroke rehabilitation: A systematic scoping review.

Stewart C, McCluskey A, Ada L, Kuys S.

Aust Occup Ther J. 2017 Jun;64(3):204-217. doi: 10.1111/1440-1630.12351. Epub 2017 Jan 10. Review.

PMID:
28071808
22.

Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.

Odell LR, Abdel-Hamid MK, Hill TA, Chau N, Young KA, Deane FM, Sakoff JA, Andersson S, Daniel JA, Robinson PJ, McCluskey A.

J Med Chem. 2017 Jan 12;60(1):349-361. doi: 10.1021/acs.jmedchem.6b01422. Epub 2016 Dec 20.

PMID:
27997171
23.

Identification and validation of small molecule modulators of the NusB-NusE interaction.

Cossar PJ, Ma C, Gordon CP, Ambrus JI, Lewis PJ, McCluskey A.

Bioorg Med Chem Lett. 2017 Jan 15;27(2):162-167. doi: 10.1016/j.bmcl.2016.11.091. Epub 2016 Dec 1.

PMID:
27964882
24.

Cytotoxicity of a Series of Norcantharidin-Inspired Tetrahydroepoxyisoindole Carboxamides.

Spare LK, Falsetta P, Gilbert J, Harman DG, Baker MA, Li F, McCluskey A, Clegg JK, Sakoff JA, Aldrich-Wright JR, Gordon CP.

ChemMedChem. 2017 Jan 20;12(2):130-145. doi: 10.1002/cmdc.201600573. Epub 2017 Jan 3.

PMID:
27921386
25.

5-Aryl-2-(naphtha-1-yl)sulfonamido-thiazol-4(5H)-ones as clathrin inhibitors.

Robertson MJ, Horatscheck A, Sauer S, von Kleist L, Baker JR, Stahlschmidt W, Nazaré M, Whiting A, Chau N, Robinson PJ, Haucke V, McCluskey A.

Org Biomol Chem. 2016 Nov 29;14(47):11266-11278.

PMID:
27853797
26.

Validity, reliability and ease of use of the disabilities of arm, shoulder and hand questionnaire in adults following stroke.

Dalton E, Lannin NA, Laver K, Ross L, Ashford S, McCluskey A, Cusick A.

Disabil Rehabil. 2017 Dec;39(24):2504-2511. doi: 10.1080/09638288.2016.1229364. Epub 2016 Oct 21.

PMID:
27767374
27.

Dynamin 2 is essential for mammalian spermatogenesis.

Redgrove KA, Bernstein IR, Pye VJ, Mihalas BP, Sutherland JM, Nixon B, McCluskey A, Robinson PJ, Holt JE, McLaughlin EA.

Sci Rep. 2016 Oct 11;6:35084. doi: 10.1038/srep35084.

28.

Recapping CAPs: The past 13 years of Critically Appraised Papers.

Cordier R, McCluskey A.

Aust Occup Ther J. 2016 Oct;63(5):357-358. doi: 10.1111/1440-1630.12329. No abstract available.

PMID:
27714865
29.

A facile hybrid 'flow and batch' access to substituted 3,4-dihydro-2H-benzo[b][1,4]oxazinones.

Lin AJ, Russell CC, Baker JR, Frailey SL, Sakoff JA, McCluskey A.

Org Biomol Chem. 2016 Sep 21;14(37):8732-8742.

PMID:
27714138
30.

Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors.

Trinh TN, McLaughlin EA, Abdel-Hamid MK, Gordon CP, Bernstein IR, Pye V, Cossar P, Sakoff JA, McCluskey A.

Org Biomol Chem. 2016 Jul 14;14(26):6304-15. doi: 10.1039/c6ob00606j. Epub 2016 Jun 7.

PMID:
27272335
31.

Effect of affordable technology on physical activity levels and mobility outcomes in rehabilitation: a protocol for the Activity and MObility UsiNg Technology (AMOUNT) rehabilitation trial.

Hassett L, van den Berg M, Lindley RI, Crotty M, McCluskey A, van der Ploeg HP, Smith ST, Schurr K, Killington M, Bongers B, Howard K, Heritier S, Togher L, Hackett M, Treacy D, Dorsch S, Wong S, Scrivener K, Chagpar S, Weber H, Pearson R, Sherrington C.

BMJ Open. 2016 Jun 6;6(6):e012074. doi: 10.1136/bmjopen-2016-012074.

32.

Older adults experience difficulty completing the lines and dots tasks of the Motor Assessment Scale.

Dettrick-Janes M, McCluskey A, Lannin NA, Scanlan JN.

Scand J Occup Ther. 2017 Sep;24(5):320-328. doi: 10.1080/11038128.2016.1187202. Epub 2016 May 26.

PMID:
27228182
33.

Type VI secretion system sheaths as nanoparticles for antigen display.

Del Tordello E, Danilchanka O, McCluskey AJ, Mekalanos JJ.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3042-7. doi: 10.1073/pnas.1524290113. Epub 2016 Feb 29.

34.

A behavior change program to increase outings delivered during therapy to stroke survivors by community rehabilitation teams: The Out-and-About trial.

McCluskey A, Ada L, Kelly PJ, Middleton S, Goodall S, Grimshaw JM, Logan P, Longworth M, Karageorge A.

Int J Stroke. 2016 Jun;11(4):425-37. doi: 10.1177/1747493016632246. Epub 2016 Feb 23.

PMID:
26906448
35.

Robenidine Analogues as Gram-Positive Antibacterial Agents.

Abraham RJ, Stevens AJ, Young KA, Russell C, Qvist A, Khazandi M, Wong HS, Abraham S, Ogunniyi AD, Page SW, O'Handley R, McCluskey A, Trott DJ.

J Med Chem. 2016 Mar 10;59(5):2126-38. doi: 10.1021/acs.jmedchem.5b01797. Epub 2016 Feb 10.

PMID:
26765953
36.

Cytotoxic compounds from Laurencia pacifica.

Zaleta-Pinet DA, Holland IP, Muñoz-Ochoa M, Murillo-Alvarez JI, Sakoff JA, van Altena IA, McCluskey A.

Org Med Chem Lett. 2014 Dec;4(1):8. doi: 10.1186/s13588-014-0008-8. Epub 2014 Sep 20.

37.

Emulsion technologies for multicellular tumour spheroid radiation assays.

McMillan KS, McCluskey AG, Sorensen A, Boyd M, Zagnoni M.

Analyst. 2016 Jan 7;141(1):100-10. doi: 10.1039/c5an01382h. Epub 2015 Oct 12.

PMID:
26456100
38.

Compliance with Australian stroke guideline recommendations for outdoor mobility and transport training by post-inpatient rehabilitation services: An observational cohort study.

McCluskey A, Ada L, Kelly PJ, Middleton S, Goodall S, Grimshaw JM, Logan P, Longworth M, Karageorge A.

BMC Health Serv Res. 2015 Jul 29;15:296. doi: 10.1186/s12913-015-0952-7.

39.

1,8-Naphthalimide derivatives: new leads against dynamin I GTPase activity.

Abdel-Hamid MK, Macgregor KA, Odell LR, Chau N, Mariana A, Whiting A, Robinson PJ, McCluskey A.

Org Biomol Chem. 2015 Aug 7;13(29):8016-28. doi: 10.1039/c5ob00751h. Epub 2015 Jun 29.

PMID:
26118967
40.

Feasibility of a home-based program to improve handwriting after stroke: a pilot study.

Simpson B, McCluskey A, Lannin N, Cordier R.

Disabil Rehabil. 2016;38(7):673-82. doi: 10.3109/09638288.2015.1059495. Epub 2015 Jun 22.

PMID:
26095817
41.

The expanding utility of continuous flow hydrogenation.

Cossar PJ, Hizartzidis L, Simone MI, McCluskey A, Gordon CP.

Org Biomol Chem. 2015 Jul 14;13(26):7119-30. doi: 10.1039/c5ob01067e. Epub 2015 Jun 15. Review.

PMID:
26073166
42.

Computerised cognitive training programs improved the cognitive performance of healthy older adults on some cognitive tests including memory, speed of information processing and visuospatial skills.

Laver K, Hamilton C, McCluskey A.

Aust Occup Ther J. 2015 Jun;62(3):223-4. doi: 10.1111/1440-1630.12209. No abstract available.

PMID:
26058781
43.

The synthesis and biological activity of novel anthracenone-pyranones and anthracenone-furans.

Rixson JE, Abraham JR, Egoshi Y, Skelton BW, Young K, Gilbert J, Sakoff JA, Gericke KM, McCluskey A, Stewart SG.

Bioorg Med Chem. 2015 Jul 1;23(13):3552-65. doi: 10.1016/j.bmc.2015.04.032. Epub 2015 Apr 22.

PMID:
25979375
44.

Small molecules demonstrate the role of dynamin as a bi-directional regulator of the exocytosis fusion pore and vesicle release.

Jackson J, Papadopulos A, Meunier FA, McCluskey A, Robinson PJ, Keating DJ.

Mol Psychiatry. 2015 Jul;20(7):810-9. doi: 10.1038/mp.2015.56. Epub 2015 May 5.

PMID:
25939402
45.

Role of acidic residues in helices TH8-TH9 in membrane interactions of the diphtheria toxin T domain.

Ghatak C, Rodnin MV, Vargas-Uribe M, McCluskey AJ, Flores-Canales JC, Kurnikova M, Ladokhin AS.

Toxins (Basel). 2015 Apr 14;7(4):1303-23. doi: 10.3390/toxins7041303.

46.

Glycogen synthase kinase 3 regulates acrosomal exocytosis in mouse spermatozoa via dynamin phosphorylation.

Reid AT, Anderson AL, Roman SD, McLaughlin EA, McCluskey A, Robinson PJ, Aitken RJ, Nixon B.

FASEB J. 2015 Jul;29(7):2872-82. doi: 10.1096/fj.14-265553. Epub 2015 Mar 25.

PMID:
25808536
47.

Phenothiazine-derived antipsychotic drugs inhibit dynamin and clathrin-mediated endocytosis.

Daniel JA, Chau N, Abdel-Hamid MK, Hu L, von Kleist L, Whiting A, Krishnan S, Maamary P, Joseph SR, Simpson F, Haucke V, McCluskey A, Robinson PJ.

Traffic. 2015 Jun;16(6):635-54. doi: 10.1111/tra.12272. Epub 2015 Apr 9.

48.

Role of dynamin in elongated cell migration in a 3D matrix.

Lees JG, Gorgani NN, Ammit AJ, McCluskey A, Robinson PJ, O'Neill GM.

Biochim Biophys Acta. 2015 Mar;1853(3):611-8. doi: 10.1016/j.bbamcr.2014.12.008. Epub 2014 Dec 10.

49.

Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway.

Caì Y, Postnikova EN, Bernbaum JG, Yú SQ, Mazur S, Deiuliis NM, Radoshitzky SR, Lackemeyer MG, McCluskey A, Robinson PJ, Haucke V, Wahl-Jensen V, Bailey AL, Lauck M, Friedrich TC, O'Connor DH, Goldberg TL, Jahrling PB, Kuhn JH.

J Virol. 2015 Jan;89(1):844-56. doi: 10.1128/JVI.02697-14. Epub 2014 Oct 29.

50.

An efficient continuous flow approach to furnish furan-based biaryls.

Trinh TN, Hizartzidis L, Lin AJ, Harman DG, McCluskey A, Gordon CP.

Org Biomol Chem. 2014 Dec 21;12(47):9562-71. doi: 10.1039/c4ob01641f. Epub 2014 Oct 21.

PMID:
25333944

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