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Items: 30

1.

Role of receptor occupancy assays by flow cytometry in drug development.

Stewart JJ, Green CL, Jones N, Liang M, Xu Y, Wilkins DE, Moulard M, Czechowska K, Lanham D, McCloskey TW, Ferbas J, van der Strate BW, Högerkorp CM, Wyant T, Lackey A, Litwin V.

Cytometry B Clin Cytom. 2016 Mar;90(2):110-6. doi: 10.1002/cyto.b.21355. Epub 2016 Feb 16. Review.

2.

CD8+ T cells in HIV disease exhibit cytokine receptor perturbation and poor T cell receptor activation but are responsive to gamma-chain cytokine-driven proliferation.

Pahwa R, McCloskey TW, Aroniadis OC, Strbo N, Krishnan S, Pahwa S.

J Infect Dis. 2006 Mar 15;193(6):879-87. Epub 2006 Feb 9.

PMID:
16479523
3.

Aggregates of oxidized proteins (lipofuscin) induce apoptosis through proteasome inhibition and dysregulation of proapoptotic proteins.

Powell SR, Wang P, Divald A, Teichberg S, Haridas V, McCloskey TW, Davies KJ, Katzeff H.

Free Radic Biol Med. 2005 Apr 15;38(8):1093-101.

PMID:
15780767
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6.

Alterations in T-cell receptor Vbeta repertoire of CD4 and CD8 T lymphocytes in human immunodeficiency virus-infected children.

Kharbanda M, McCloskey TW, Pahwa R, Sun M, Pahwa S.

Clin Diagn Lab Immunol. 2003 Jan;10(1):53-8.

7.

T cell receptor V beta repertoire of the antigen specific CD8 T lymphocyte subset of HIV infected children.

McCloskey TW, Haridas V, Pahwa R, Pahwa S.

AIDS. 2002 Jul 26;16(11):1459-65.

PMID:
12131183
8.

Human immunodeficiency virus gag and pol-specific CD8 T cells in perinatal HIV infection.

McCloskey TW, Haridas V, Pahwa R, Pahwa S.

Cytometry. 2001 Oct 15;46(5):265-70.

PMID:
11746101
10.

Apoptosis in T-lymphocyte subsets in human immunodeficiency virus-infected children measured immediately ex vivo and following in vitro activation.

Niehues T, McCloskey TW, Ndagijimana J, Horneff G, Wahn V, Pahwa S.

Clin Diagn Lab Immunol. 2001 Jan;8(1):74-8.

11.
12.

Alterations in apoptosis of cord and adult peripheral blood mononuclear cells induced by in vitro infection with respiratory syncytial virus.

Krilov LR, McCloskey TW, Harkness SH, Pontrelli L, Pahwa S.

J Infect Dis. 2000 Jan;181(1):349-53.

PMID:
10608787
15.

CD95 expression and apoptosis during pediatric HIV infection: early upregulation of CD95 expression.

McCloskey TW, Oyaizu N, Bakshi S, Kowalski R, Kohn N, Pahwa S.

Clin Immunol Immunopathol. 1998 Apr;87(1):33-41.

PMID:
9576008
16.

Signals transduced through the CD4 molecule interfere with TCR/CD3-mediated ras activation leading to T cell anergy/apoptosis.

Tamma SM, Chirmule N, McCloskey TW, Oyaizu N, Kalyanaraman VS, Pahwa S.

Clin Immunol Immunopathol. 1997 Nov;85(2):195-201.

PMID:
9344703
17.

Immunophenotyping of T lymphocytes by three-color flow cytometry in healthy newborns, children, and adults.

McCloskey TW, Cavaliere T, Bakshi S, Harper R, Fagin J, Kohn N, Pahwa S.

Clin Immunol Immunopathol. 1997 Jul;84(1):46-55.

PMID:
9191883
18.

Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection.

Oyaizu N, Adachi Y, Hashimoto F, McCloskey TW, Hosaka N, Kayagaki N, Yagita H, Pahwa S.

J Immunol. 1997 Mar 1;158(5):2456-63.

PMID:
9036997
19.

Dual role of HIV Tat in regulation of apoptosis in T cells.

McCloskey TW, Ott M, Tribble E, Khan SA, Teichberg S, Paul MO, Pahwa S, Verdin E, Chirmule N.

J Immunol. 1997 Jan 15;158(2):1014-9.

PMID:
8993024
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23.

Requirement of p56lck in T-cell receptor/CD3-mediated apoptosis and Fas-ligand induction in Jurkat cells.

Oyaizu N, Than S, McCloskey TW, Pahwa S.

Biochem Biophys Res Commun. 1995 Aug 24;213(3):994-1001.

PMID:
7544583
24.

HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71).

Chirmule N, McCloskey TW, Hu R, Kalyanaraman VS, Pahwa S.

J Immunol. 1995 Jul 15;155(2):917-24.

PMID:
7541827
25.

Expression of the Fas antigen in patients infected with human immunodeficiency virus.

McCloskey TW, Oyaizu N, Kaplan M, Pahwa S.

Cytometry. 1995 Jun 15;22(2):111-4.

26.

Mechanism of apoptosis in peripheral blood mononuclear cells of HIV-infected patients.

Oyaizu N, McCloskey TW, Than S, Hu R, Pahwa S.

Adv Exp Med Biol. 1995;374:101-14.

PMID:
7572384
27.
28.

Use of a flow cytometric assay to quantitate apoptosis in human lymphocytes.

McCloskey TW, Oyaizu N, Coronesi M, Pahwa S.

Clin Immunol Immunopathol. 1994 Apr;71(1):14-8.

PMID:
8137555
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