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Items: 1 to 50 of 66

1.

Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel.

LaFavers KA, Macedo E, Garimella PS, Lima C, Khan S, Myslinski J, McClintick J, Witzmann FA, Winfree S, Phillips CL, Hato T, Dagher PC, Wu XR, El-Achkar TM, Micanovic R.

Sci Transl Med. 2019 Oct 2;11(512). pii: eaaw3639. doi: 10.1126/scitranslmed.aaw3639.

PMID:
31578243
2.

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism.

Kapoor M, Wang JC, Farris SP, Liu Y, McClintick J, Gupta I, Meyers JL, Bertelsen S, Chao M, Nurnberger J, Tischfield J, Harari O, Zeran L, Hesselbrock V, Bauer L, Raj T, Porjesz B, Agrawal A, Foroud T, Edenberg HJ, Mayfield RD, Goate A.

Transl Psychiatry. 2019 Feb 14;9(1):89. doi: 10.1038/s41398-019-0384-y.

3.

Ethanol activates immune response in lymphoblastoid cells.

McClintick JN, Tischfield JA, Deng L, Kapoor M, Xuei X, Edenberg HJ.

Alcohol. 2019 Sep;79:81-91. doi: 10.1016/j.alcohol.2019.01.001. Epub 2019 Jan 9.

PMID:
30639126
4.

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG; 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A.

Nat Neurosci. 2018 Dec;21(12):1656-1669. doi: 10.1038/s41593-018-0275-1. Epub 2018 Nov 26.

5.

Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review.

Edenberg HJ, McClintick JN.

Alcohol Clin Exp Res. 2018 Dec;42(12):2281-2297. doi: 10.1111/acer.13904. Epub 2018 Nov 11. Review.

PMID:
30320893
6.

Gene expression changes in the ventral hippocampus and medial prefrontal cortex of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking.

McClintick JN, McBride WJ, Bell RL, Ding ZM, Liu Y, Xuei X, Edenberg HJ.

Alcohol. 2018 May;68:37-47. doi: 10.1016/j.alcohol.2017.09.002. Epub 2017 Sep 14.

7.

Endotoxin Preconditioning Reprograms S1 Tubules and Macrophages to Protect the Kidney.

Hato T, Zollman A, Plotkin Z, El-Achkar TM, Maier BF, Pay SL, Dube S, Cabral P, Yoshimoto M, McClintick J, Dagher PC.

J Am Soc Nephrol. 2018 Jan;29(1):104-117. doi: 10.1681/ASN.2017060624. Epub 2017 Oct 10.

8.

Estrogen receptor-dependent attenuation of hypoxia-induced changes in the lung genome of pulmonary hypertension rats.

Frump AL, Albrecht ME, McClintick JN, Lahm T.

Pulm Circ. 2017 Mar 27;7(1):232-243. doi: 10.1177/2045893217702055. eCollection 2017 Mar.

9.

Inflammation and vascular smooth muscle cell dedifferentiation following carotid artery ligation.

Herring BP, Hoggatt AM, Griffith SL, McClintick JN, Gallagher PJ.

Physiol Genomics. 2017 Mar 1;49(3):115-126. doi: 10.1152/physiolgenomics.00095.2016. Epub 2016 Dec 30.

10.

Effects of Lithium Monotherapy for Bipolar Disorder on Gene Expression in Peripheral Lymphocytes.

Anand A, McClintick JN, Murrell J, Karne H, Nurnberger JI, Edenberg HJ.

Mol Neuropsychiatry. 2016 Oct;2(3):115-123. Epub 2016 Jun 29.

11.

Obesity alters molecular and functional cardiac responses to ischemia/reperfusion and glucagon-like peptide-1 receptor agonism.

Sassoon DJ, Goodwill AG, Noblet JN, Conteh AM, Herring BP, McClintick JN, Tune JD, Mather KJ.

Basic Res Cardiol. 2016 Jul;111(4):43. doi: 10.1007/s00395-016-0563-4. Epub 2016 May 27.

12.

Gene Expression Changes in Glutamate and GABA-A Receptors, Neuropeptides, Ion Channels, and Cholesterol Synthesis in the Periaqueductal Gray Following Binge-Like Alcohol Drinking by Adolescent Alcohol-Preferring (P) Rats.

McClintick JN, McBride WJ, Bell RL, Ding ZM, Liu Y, Xuei X, Edenberg HJ.

Alcohol Clin Exp Res. 2016 May;40(5):955-68. doi: 10.1111/acer.13056. Epub 2016 Apr 8.

13.

A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.

Bell RL, Hauser S, Rodd ZA, Liang T, Sari Y, McClintick J, Rahman S, Engleman EA.

Int Rev Neurobiol. 2016;126:179-261. doi: 10.1016/bs.irn.2016.02.017. Epub 2016 Mar 21. Review.

14.

Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings.

Bell RL, Hauser SR, McClintick J, Rahman S, Edenberg HJ, Szumlinski KK, McBride WJ.

Prog Mol Biol Transl Sci. 2016;137:41-85. doi: 10.1016/bs.pmbts.2015.10.018. Epub 2015 Nov 24. Review.

15.

Differential miRNA Expression in Cells and Matrix Vesicles in Vascular Smooth Muscle Cells from Rats with Kidney Disease.

Chaturvedi P, Chen NX, O'Neill K, McClintick JN, Moe SM, Janga SC.

PLoS One. 2015 Jun 26;10(6):e0131589. doi: 10.1371/journal.pone.0131589. eCollection 2015.

16.

Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior.

Salvatore JE, Edwards AC, McClintick JN, Bigdeli TB, Adkins A, Aliev F, Edenberg HJ, Foroud T, Hesselbrock V, Kramer J, Nurnberger JI, Schuckit M, Tischfield JA, Xuei X, Dick DM.

Transl Psychiatry. 2015 Apr 28;5:e558. doi: 10.1038/tp.2015.36.

17.

Pachymic acid inhibits growth and induces apoptosis of pancreatic cancer in vitro and in vivo by targeting ER stress.

Cheng S, Swanson K, Eliaz I, McClintick JN, Sandusky GE, Sliva D.

PLoS One. 2015 Apr 27;10(4):e0122270. doi: 10.1371/journal.pone.0122270. eCollection 2015.

18.

Epigenetic Regulation of Placenta-Specific 8 Contributes to Altered Function of Endothelial Colony-Forming Cells Exposed to Intrauterine Gestational Diabetes Mellitus.

Blue EK, Sheehan BM, Nuss ZV, Boyle FA, Hocutt CM, Gohn CR, Varberg KM, McClintick JN, Haneline LS.

Diabetes. 2015 Jul;64(7):2664-75. doi: 10.2337/db14-1709. Epub 2015 Feb 26.

19.

Reduction of alcohol drinking of alcohol-preferring (P) and high-alcohol drinking (HAD1) rats by targeting phosphodiesterase-4 (PDE4).

Franklin KM, Hauser SR, Lasek AW, McClintick J, Ding ZM, McBride WJ, Bell RL.

Psychopharmacology (Berl). 2015 Jul;232(13):2251-62. doi: 10.1007/s00213-014-3852-3. Epub 2015 Jan 15.

20.

Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking.

McClintick JN, McBride WJ, Bell RL, Ding ZM, Liu Y, Xuei X, Edenberg HJ.

Pharmacol Biochem Behav. 2015 Feb;129:87-96. doi: 10.1016/j.pbb.2014.12.007. Epub 2014 Dec 24.

21.

Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression.

McClintick JN, Brooks AI, Deng L, Liang L, Wang JC, Kapoor M, Xuei X, Foroud T, Tischfield JA, Edenberg HJ.

Alcohol. 2014 Sep;48(6):603-10. doi: 10.1016/j.alcohol.2014.07.004. Epub 2014 Jul 22.

22.

Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα.

Baird TD, Palam LR, Fusakio ME, Willy JA, Davis CM, McClintick JN, Anthony TG, Wek RC.

Mol Biol Cell. 2014 May;25(10):1686-97. doi: 10.1091/mbc.E14-02-0704. Epub 2014 Mar 19.

23.

Changes in gene expression within the extended amygdala following binge-like alcohol drinking by adolescent alcohol-preferring (P) rats.

McBride WJ, Kimpel MW, McClintick JN, Ding ZM, Edenberg HJ, Liang T, Rodd ZA, Bell RL.

Pharmacol Biochem Behav. 2014 Feb;117:52-60. doi: 10.1016/j.pbb.2013.12.009. Epub 2013 Dec 16.

24.

Molecular basis for impaired collateral artery growth in the spontaneously hypertensive rat: insight from microarray analysis.

Unthank JL, McClintick JN, Labarrere CA, Li L, Distasi MR, Miller SJ.

Physiol Rep. 2013 Jul;1(2):e0005. doi: 10.1002/phy2.5. Epub 2013 Jun 26.

25.

Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects.

Sarmah S, Muralidharan P, Curtis CL, McClintick JN, Buente BB, Holdgrafer DJ, Ogbeifun O, Olorungbounmi OC, Patino L, Lucas R, Gilbert S, Groninger ES, Arciero J, Edenberg HJ, Marrs JA.

Biol Open. 2013 Aug 14;2(10):1013-21. doi: 10.1242/bio.20135546. eCollection 2013.

26.

Gene expression within the extended amygdala of 5 pairs of rat lines selectively bred for high or low ethanol consumption.

McBride WJ, Kimpel MW, McClintick JN, Ding ZM, Hyytia P, Colombo G, Liang T, Edenberg HJ, Lumeng L, Bell RL.

Alcohol. 2013 Nov;47(7):517-29. doi: 10.1016/j.alcohol.2013.08.004. Epub 2013 Oct 1.

27.

Stress-response pathways are altered in the hippocampus of chronic alcoholics.

McClintick JN, Xuei X, Tischfield JA, Goate A, Foroud T, Wetherill L, Ehringer MA, Edenberg HJ.

Alcohol. 2013 Nov;47(7):505-15. doi: 10.1016/j.alcohol.2013.07.002. Epub 2013 Aug 24.

28.

CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis.

Teske BF, Fusakio ME, Zhou D, Shan J, McClintick JN, Kilberg MS, Wek RC.

Mol Biol Cell. 2013 Aug;24(15):2477-90. doi: 10.1091/mbc.E13-01-0067. Epub 2013 Jun 12.

29.

Changes in gene expression within the ventral tegmental area following repeated excessive binge-like alcohol drinking by alcohol-preferring (P) rats.

McBride WJ, Kimpel MW, McClintick JN, Ding ZM, Hauser SR, Edenberg HJ, Bell RL, Rodd ZA.

Alcohol. 2013 Aug;47(5):367-80. doi: 10.1016/j.alcohol.2013.04.002. Epub 2013 May 25.

30.

Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization.

Chambers RA, McClintick JN, Sentir AM, Berg SA, Runyan M, Choi KH, Edenberg HJ.

Genes Brain Behav. 2013 Jul;12(5):564-75. doi: 10.1111/gbb.12051. Epub 2013 Jun 22.

31.

A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.

Wang JC, Foroud T, Hinrichs AL, Le NX, Bertelsen S, Budde JP, Harari O, Koller DL, Wetherill L, Agrawal A, Almasy L, Brooks AI, Bucholz K, Dick D, Hesselbrock V, Johnson EO, Kang S, Kapoor M, Kramer J, Kuperman S, Madden PA, Manz N, Martin NG, McClintick JN, Montgomery GW, Nurnberger JI Jr, Rangaswamy M, Rice J, Schuckit M, Tischfield JA, Whitfield JB, Xuei X, Porjesz B, Heath AC, Edenberg HJ, Bierut LJ, Goate AM.

Mol Psychiatry. 2013 Nov;18(11):1218-24. doi: 10.1038/mp.2012.143. Epub 2012 Oct 23.

32.

Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumption.

McBride WJ, Kimpel MW, McClintick JN, Ding ZM, Hyytia P, Colombo G, Edenberg HJ, Lumeng L, Bell RL.

Pharmacol Biochem Behav. 2012 Aug;102(2):275-85. doi: 10.1016/j.pbb.2012.04.016. Epub 2012 May 10.

33.

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

Teske BF, Wek SA, Bunpo P, Cundiff JK, McClintick JN, Anthony TG, Wek RC.

Mol Biol Cell. 2011 Nov;22(22):4390-405. doi: 10.1091/mbc.E11-06-0510. Epub 2011 Sep 14.

34.

Alteration of gene expression by alcohol exposure at early neurulation.

Zhou FC, Zhao Q, Liu Y, Goodlett CR, Liang T, McClintick JN, Edenberg HJ, Li L.

BMC Genomics. 2011 Feb 21;12:124. doi: 10.1186/1471-2164-12-124.

35.

A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers.

Herbert BS, Chanoux RA, Liu Y, Baenziger PH, Goswami CP, McClintick JN, Edenberg HJ, Pennington RE, Lipkin SM, Kopelovich L.

Oncotarget. 2010 Oct;1(6):405-22.

36.

Prediction of postoperative recurrence-free survival in non-small cell lung cancer by using an internationally validated gene expression model.

Mitra R, Lee J, Jo J, Milani M, McClintick JN, Edenberg HJ, Kesler KA, Rieger KM, Badve S, Cummings OW, Mohiuddin A, Thomas DG, Luo X, Juliar BE, Li L, Mesaros C, Blair IA, Srirangam A, Kratzke RA, McDonald CJ, Kim J, Potter DA.

Clin Cancer Res. 2011 May 1;17(9):2934-46. doi: 10.1158/1078-0432.CCR-10-1803. Epub 2011 Jan 17.

37.

Toxoplasma gondii lysine acetyltransferase GCN5-A functions in the cellular response to alkaline stress and expression of cyst genes.

Naguleswaran A, Elias EV, McClintick J, Edenberg HJ, Sullivan WJ Jr.

PLoS Pathog. 2010 Dec 16;6(12):e1001232. doi: 10.1371/journal.ppat.1001232.

38.

Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast.

Staschke KA, Dey S, Zaborske JM, Palam LR, McClintick JN, Pan T, Edenberg HJ, Wek RC.

J Biol Chem. 2010 May 28;285(22):16893-911. doi: 10.1074/jbc.M110.121947. Epub 2010 Mar 16.

39.

Genome-wide association study of alcohol dependence implicates a region on chromosome 11.

Edenberg HJ, Koller DL, Xuei X, Wetherill L, McClintick JN, Almasy L, Bierut LJ, Bucholz KK, Goate A, Aliev F, Dick D, Hesselbrock V, Hinrichs A, Kramer J, Kuperman S, Nurnberger JI Jr, Rice JP, Schuckit MA, Taylor R, Todd Webb B, Tischfield JA, Porjesz B, Foroud T.

Alcohol Clin Exp Res. 2010 May;34(5):840-52. doi: 10.1111/j.1530-0277.2010.01156.x. Epub 2010 Mar 1.

40.

Candidate genes for alcohol preference identified by expression profiling in alcohol-preferring and -nonpreferring reciprocal congenic rats.

Liang T, Kimpel MW, McClintick JN, Skillman AR, McCall K, Edenberg HJ, Carr LG.

Genome Biol. 2010;11(2):R11. doi: 10.1186/gb-2010-11-2-r11. Epub 2010 Feb 3.

41.

Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking.

McBride WJ, Kimpel MW, Schultz JA, McClintick JN, Edenberg HJ, Bell RL.

Alcohol. 2010 Mar;44(2):171-83. doi: 10.1016/j.alcohol.2009.12.001. Epub 2010 Jan 29.

42.

Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors.

Benson EA, Goebl MG, Yang FC, Kapur R, McClintick J, Sanghani S, Clapp DW, Harrington MA.

Exp Hematol. 2010 Feb;38(2):71-81. doi: 10.1016/j.exphem.2009.11.006. Epub 2009 Nov 23.

43.

Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption.

Bell RL, Kimpel MW, McClintick JN, Strother WN, Carr LG, Liang T, Rodd ZA, Mayfield RD, Edenberg HJ, McBride WJ.

Pharmacol Biochem Behav. 2009 Nov;94(1):131-47. doi: 10.1016/j.pbb.2009.07.019. Epub 2009 Aug 8.

44.

Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: a proteomics study.

McBride WJ, Schultz JA, Kimpel MW, McClintick JN, Wang M, You J, Rodd ZA.

Pharmacol Biochem Behav. 2009 Apr;92(2):304-13. doi: 10.1016/j.pbb.2008.12.019. Epub 2009 Jan 6.

45.
46.

Mapping of trans-acting regulatory factors from microarray data.

McClintick JN, Liu Y, Edenberg HJ.

BMC Proc. 2007;1 Suppl 1:S155. Epub 2007 Dec 18.

47.

Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats.

Rodd ZA, Kimpel MW, Edenberg HJ, Bell RL, Strother WN, McClintick JN, Carr LG, Liang T, McBride WJ.

Pharmacol Biochem Behav. 2008 Jun;89(4):481-98. doi: 10.1016/j.pbb.2008.01.023. Epub 2008 Feb 26.

48.

Summary of contributions to GAW15 Group 16: processing/normalization of expression traits.

Labbe A, McClintick J, Martinez M, Beyenne J, Chen L, de Andrade M, Edenberg HJ, Kim Y, Liu KY, Liu Y, Ma J, Peng B, Peng J, Peralta JM, Qin S, Roth MP, Wang P.

Genet Epidemiol. 2007;31 Suppl 1:S132-8.

PMID:
18046755
49.

Dysregulated immune profiles for skin and dendritic cells are associated with increased host susceptibility to Haemophilus ducreyi infection in human volunteers.

Humphreys TL, Li L, Li X, Janowicz DM, Fortney KR, Zhao Q, Li W, McClintick J, Katz BP, Wilkes DS, Edenberg HJ, Spinola SM.

Infect Immun. 2007 Dec;75(12):5686-97. Epub 2007 Sep 24.

50.

Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions.

Kimpel MW, Strother WN, McClintick JN, Carr LG, Liang T, Edenberg HJ, McBride WJ.

Alcohol. 2007 Mar;41(2):95-132.

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