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Increasing Incidence of Nonalcoholic Steatohepatitis as an Indication for Liver Transplantation in Australia and New Zealand.

Calzadilla-Bertot L, Jeffrey GP, Jacques B, McCaughan G, Crawford M, Angus P, Jones R, Gane E, Munn S, Macdonald G, Fawcett J, Wigg A, Chen J, Fink M, Adams LA.

Liver Transpl. 2019 Jan;25(1):25-34. doi: 10.1002/lt.25361.


Longitudinal immunosuppression data can minimize misclassification bias in solid organ transplantation cohorts.

Laaksonen MA, Webster AC, McCaughan GW, Keogh AM, Grulich AE, Vajdic CM.

Clin Transplant. 2018 Dec 26:e13470. doi: 10.1111/ctr.13470. [Epub ahead of print]


APASL clinical practice recommendation: how to treat HCV-infected patients with renal impairment?

Kanda T, Lau GKK, Wei L, Moriyama M, Yu ML, Chuang WL, Ibrahim A, Lesmana CRA, Sollano J, Kumar M, Jindal A, Sharma BC, Hamid SS, Dokmeci AK, Mamun-Al-Mahtab, McCaughan GW, Wasim J, Crawford DHG, Kao JH, Yokosuka O, Sarin SK, Omata M.

Hepatol Int. 2018 Dec 11. doi: 10.1007/s12072-018-9915-5. [Epub ahead of print]


Aggressive nutrition intervention reduces ascites and frequency of paracentesis in malnourished patients with cirrhosis and ascites.

Vidot H, Bowen DG, Carey S, McCaughan GW, Allman-Farinelli M, Shackel NA.

JGH Open. 2017 Oct 31;1(3):92-97. doi: 10.1002/jgh3.12016. eCollection 2017 Nov.


Fibroblast activation protein in liver fibrosis.

Lay AJ, Zhang HE, McCaughan GW, Gorrell MD.

Front Biosci (Landmark Ed). 2019 Jan 1;24:1-17.


An unexpected diagnosis: leukaemic presentation of blastic plasmacytoid dendritic cell neoplasm with massive splenomegaly.

Blennerhassett R, McCaughan G, Tegg E.

Pathology. 2018 Dec;50(7):773-775. doi: 10.1016/j.pathol.2018.05.007. Epub 2018 Sep 28. No abstract available.


Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics.

Zhang HE, Hamson EJ, Koczorowska MM, Tholen S, Chowdhury S, Bailey CG, Lay AJ, Twigg SM, Lee Q, Roediger B, Biniossek ML, O'Rourke MB, McCaughan GW, Keane FM, Schilling O, Gorrell MD.

Mol Cell Proteomics. 2019 Jan;18(1):65-85. doi: 10.1074/mcp.RA118.001046. Epub 2018 Sep 26.


Anticoagulation at the extremes of body weight: choices and dosing.

McCaughan GJB, Favaloro EJ, Pasalic L, Curnow J.

Expert Rev Hematol. 2018 Oct;11(10):817-828. doi: 10.1080/17474086.2018.1517040. Epub 2018 Sep 25.


Randomised clinical trial: oral taurine supplementation versus placebo reduces muscle cramps in patients with chronic liver disease.

Vidot H, Cvejic E, Carey S, Strasser SI, McCaughan GW, Allman-Farinelli M, Shackel NA.

Aliment Pharmacol Ther. 2018 Oct;48(7):704-712. doi: 10.1111/apt.14950. Epub 2018 Aug 23.


How to select the appropriate "neoadjuvant therapy" for hepatocellular carcinoma.

Liu K, McCaughan GW.

Expert Opin Pharmacother. 2018 Aug;19(11):1167-1170. doi: 10.1080/14656566.2018.1498843. Epub 2018 Jul 16. No abstract available.


Multiple liver insults synergize to accelerate experimental hepatocellular carcinoma.

Henderson JM, Polak N, Chen J, Roediger B, Weninger W, Kench JG, McCaughan GW, Zhang HE, Gorrell MD.

Sci Rep. 2018 Jul 6;8(1):10283. doi: 10.1038/s41598-018-28486-8.


Epidemiology and Etiologic Associations of Non-alcoholic Fatty Liver Disease and Associated HCC.

Liu K, McCaughan GW.

Adv Exp Med Biol. 2018;1061:3-18. doi: 10.1007/978-981-10-8684-7_2. Review.


Frailty in advanced liver disease.

Laube R, Wang H, Park L, Heyman JK, Vidot H, Majumdar A, Strasser SI, McCaughan GW, Liu K.

Liver Int. 2018 Dec;38(12):2117-2128. doi: 10.1111/liv.13917. Epub 2018 Jul 15. Review.


Circulating Endothelial Progenitor Cells Present an Inflammatory Phenotype and Function in Patients With Alcoholic Liver Cirrhosis.

Kaur S, Sehgal R, Shastry SM, McCaughan G, McGuire HM, Fazekas St de Groth B, Sarin S, Trehanpati N, Seth D.

Front Physiol. 2018 May 22;9:556. doi: 10.3389/fphys.2018.00556. eCollection 2018.


Molecular profiling of postreperfusion milieu determines acute kidney injury after liver transplantation: A prospective study.

Pulitano C, Ho P, Verran D, Sandroussi C, Joseph D, Bowen DG, McCaughan GW, Crawford M, Shackel N.

Liver Transpl. 2018 Jul;24(7):922-931. doi: 10.1002/lt.25178.


HIT or miss? A comprehensive contemporary investigation of laboratory tests for heparin induced thrombocytopenia.

Favaloro EJ, McCaughan G, Mohammed S, Lau KKE, Gemmell R, Cavanaugh L, Donikian D, Kondo M, Brighton T, Pasalic L.

Pathology. 2018 Jun;50(4):426-436. doi: 10.1016/j.pathol.2017.11.089. Epub 2018 Apr 17.


Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice.

Chen J, Qi Y, Zhao Y, Kaczorowski D, Couttas TA, Coleman PR, Don AS, Bertolino P, Gamble JR, Vadas MA, Xia P, McCaughan GW.

Oncotarget. 2018 Feb 26;9(21):15635-15649. doi: 10.18632/oncotarget.24583. eCollection 2018 Mar 20.


Novel TOF-MS Means of Quantifying ApoAI Amyloid Protein Load After Combined Liver Kidney Transplantation.

Richards KG, Brennan SO, McCaughan GW, Chadban SJ.

Transplantation. 2018 May;102(5):e192-e193. doi: 10.1097/TP.0000000000002116. No abstract available.


Prevalence and outcomes of pancreatic cystic neoplasms in liver transplant recipients.

Liu K, Joshi V, van Camp L, Yang QW, Baars JE, Strasser SI, McCaughan GW, Majumdar A, Saxena P, Kaffes AJ.

World J Gastroenterol. 2017 Dec 28;23(48):8526-8532. doi: 10.3748/wjg.v23.i48.8526.


Anti-PD-1-induced high-grade hepatitis associated with corticosteroid-resistant T cells: a case report.

McGuire HM, Shklovskaya E, Edwards J, Trevillian PR, McCaughan GW, Bertolino P, McKenzie C, Gourlay R, Gallagher SJ, Fazekas de St Groth B, Hersey P.

Cancer Immunol Immunother. 2018 Apr;67(4):563-573. doi: 10.1007/s00262-017-2107-7. Epub 2017 Dec 30.


Acquired haemophilia A complicating alemtuzumab therapy for multiple sclerosis.

McCaughan G, Massey J, Sutton I, Curnow J.

BMJ Case Rep. 2017 Dec 5;2017. pii: bcr-2017-223016. doi: 10.1136/bcr-2017-223016.


Sofosbuvir and daclatasvir therapy in patients with hepatitis C-related advanced decompensated liver disease (MELD ≥ 15).

McCaughan GW, Thwaites PA, Roberts SK, Strasser SI, Mitchell J, Morales B, Mason S, Gow P, Wigg A, Tallis C, Jeffrey G, George J, Thompson AJ, Parker FC, Angus PW; Australian Liver Association Clinical Research Network.

Aliment Pharmacol Ther. 2018 Feb;47(3):401-411. doi: 10.1111/apt.14404. Epub 2017 Dec 5.


Extracorporeal cellular therapy (ELAD) in severe alcoholic hepatitis: A multinational, prospective, controlled, randomized trial.

Thompson J, Jones N, Al-Khafaji A, Malik S, Reich D, Munoz S, MacNicholas R, Hassanein T, Teperman L, Stein L, Duarte-Rojo A, Malik R, Adhami T, Asrani S, Shah N, Gaglio P, Duddempudi A, Borg B, Jalan R, Brown R, Patton H, Satoskar R, Rossi S, Parikh A, ElSharkawy A, Mantry P, Sher L, Wolf D, Hart M, Landis C, Wigg A, Habib S, McCaughan G, Colquhoun S, Henry A, Bedard P, Landeen L, Millis M, Ashley R, Frank W, Henry A, Stange J, Subramanian R; VTI-208 Study Group.

Liver Transpl. 2018 Mar;24(3):380-393. doi: 10.1002/lt.24986.


The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury.

Gogoi-Tiwari J, Köhn-Gaone J, Giles C, Schmidt-Arras D, Gratte FD, Elsegood CL, McCaughan GW, Ramm GA, Olynyk JK, Tirnitz-Parker JEE.

J Vis Exp. 2017 Oct 21;(128). doi: 10.3791/56138.


Efficacy and Safety of Mycophenolate Mofetil in Patients With Autoimmune Hepatitis and Suboptimal Outcomes After Standard Therapy.

Roberts SK, Lim R, Strasser S, Nicoll A, Gazzola A, Mitchell J, Siow W, Khoo T, Hamarneh Z, Weltman M, Gow P, Janko N, Tse E, Mishra G, Cheng EH, Levy M, Cheng W, Sood S, Skoien R, Mitchell J, Zekry A, George J, MacQuillan G, Wigg A, Stuart K, Sievert W, McCaughan G; ALA Clinical Research Network.

Clin Gastroenterol Hepatol. 2018 Feb;16(2):268-277. doi: 10.1016/j.cgh.2017.09.063. Epub 2017 Oct 16.


A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment.

Sierro F, Evrard M, Rizzetto S, Melino M, Mitchell AJ, Florido M, Beattie L, Walters SB, Tay SS, Lu B, Holz LE, Roediger B, Wong YC, Warren A, Ritchie W, McGuffog C, Weninger W, Le Couteur DG, Ginhoux F, Britton WJ, Heath WR, Saunders BM, McCaughan GW, Luciani F, MacDonald KPA, Ng LG, Bowen DG, Bertolino P.

Immunity. 2017 Aug 15;47(2):374-388.e6. doi: 10.1016/j.immuni.2017.07.018.


Sclerosing peritonitis post liver transplantation: a rare condition where surgery is an important treatment option.

Kong YX, Strasser SI, McCaughan GW, Crawford M, Verran DJ.

ANZ J Surg. 2018 May;88(5):E424-E428. doi: 10.1111/ans.14128. Epub 2017 Aug 7.


Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy.

Zhao Y, Ting KK, Li J, Cogger VC, Chen J, Johansson-Percival A, Ngiow SF, Holst J, Grau G, Goel S, Muller T, Dejana E, McCaughan G, Smyth MJ, Ganss R, Vadas MA, Gamble JR.

Cancer Res. 2017 Aug 15;77(16):4434-4447. doi: 10.1158/0008-5472.CAN-16-3129. Epub 2017 Jun 27. Erratum in: Cancer Res. 2018 Oct 1;78(19):5718.


Interactions between primary sclerosing cholangitis and inflammatory bowel disease: implications in the adult liver transplant setting.

Liu K, Strasser SI, Koorey DJ, Leong RW, Solomon M, McCaughan GW.

Expert Rev Gastroenterol Hepatol. 2017 Oct;11(10):949-960. doi: 10.1080/17474124.2017.1343666. Epub 2017 Jun 21. Review.


Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply.

Liu K, Zhang X, Xu W, Chen J, Yu J, Gamble JR, McCaughan GW.

Clin Transl Gastroenterol. 2017 Jun 15;8(6):e98. doi: 10.1038/ctg.2017.28.


Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease.

Uitte de Willige S, Keane FM, Bowen DG, Malfliet JJMC, Zhang HE, Maneck B, McCaughan GW, Leebeek FWG, Rijken DC, Gorrell MD.

PLoS One. 2017 Jun 5;12(6):e0178987. doi: 10.1371/journal.pone.0178987. eCollection 2017.


Patients with non-viral liver disease have a greater tumor burden and less curative treatment options when diagnosed with hepatocellular carcinoma.

Mohsen W, Rodov M, Prakoso E, Charlton B, Bowen DG, Koorey DJ, Shackel NA, McCaughan GW, Strasser SI.

World J Gastroenterol. 2017 Apr 21;23(15):2763-2770. doi: 10.3748/wjg.v23.i15.2763.


Clinical and laboratory diagnosis of heparin induced thrombocytopenia: an update.

Favaloro EJ, McCaughan G, Pasalic L.

Pathology. 2017 Jun;49(4):346-355. doi: 10.1016/j.pathol.2017.02.005. Epub 2017 Apr 23. Review.


International Liver Transplantation Society Consensus Statement on Hepatitis C Management in Liver Transplant Recipients.

Terrault NA, Berenguer M, Strasser SI, Gadano A, Lilly L, Samuel D, Kwo PY, Agarwal K, Curry MP, Fagiuoli S, Fung JYY, Gane E, Brown KA, Burra P, Charlton M, Pessoa MG, McCaughan GW.

Transplantation. 2017 May;101(5):956-967. doi: 10.1097/TP.0000000000001704. No abstract available.


International Liver Transplantation Society Consensus Statement on Hepatitis C Management in Liver Transplant Candidates.

Terrault NA, McCaughan GW, Curry MP, Gane E, Fagiuoli S, Fung JYY, Agarwal K, Lilly L, Strasser SI, Brown KA, Gadano A, Kwo PY, Burra P, Samuel D, Charlton M, Pessoa MG, Berenguer M.

Transplantation. 2017 May;101(5):945-955. doi: 10.1097/TP.0000000000001708. No abstract available.


An update on the pathophysiology and management of polycystic liver disease.

Wong MY, McCaughan GW, Strasser SI.

Expert Rev Gastroenterol Hepatol. 2017 Jun;11(6):569-581. doi: 10.1080/17474124.2017.1309280. Epub 2017 Mar 28. Review.


Effect of viral suppression on hepatic venous pressure gradient in hepatitis C with cirrhosis and portal hypertension.

Afdhal N, Everson GT, Calleja JL, McCaughan GW, Bosch J, Brainard DM, McHutchison JG, De-Oertel S, An D, Charlton M, Reddy KR, Asselah T, Gane E, Curry MP, Forns X.

J Viral Hepat. 2017 Oct;24(10):823-831. doi: 10.1111/jvh.12706. Epub 2017 Apr 10.


The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells.

Lovelace MD, Powter EE, Coleman PR, Zhao Y, Parker A, Chang GH, Lay AJ, Hunter J, McGrath AP, Jormakka M, Bertolino P, McCaughan G, Kavallaris M, Vadas MA, Gamble JR.

Mol Biol Cell. 2017 Apr 15;28(8):1066-1078. doi: 10.1091/mbc.E16-05-0285. Epub 2017 Mar 1.


Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease.

Grzelak CA, Sigglekow ND, Tirnitz-Parker JE, Hamson EJ, Warren A, Maneck B, Chen J, Patkunanathan B, Boland J, Cheng R, Shackel NA, Seth D, Bowen DG, Martelotto LG, Watkins DN, McCaughan GW.

PLoS One. 2017 Feb 10;12(2):e0171480. doi: 10.1371/journal.pone.0171480. eCollection 2017.


Postreperfusion microcirculatory derangements after liver transplantation: Relationship to hemodynamics, serum mediators, and outcome.

Pulitano C, Joseph D, Sandroussi C, Verran D, Ho P, Debiasio A, Luongo A, McCaughan GW, Shackel NA, Crawford M.

Liver Transpl. 2017 Apr;23(4):527-536. doi: 10.1002/lt.24721.


Can response to locoregional therapy help predict longterm survival after liver transplantation for hepatocellular carcinoma? A systematic review.

Morris PD, Laurence JM, Yeo D, Crawford M, Strasser SI, McCaughan GW, Sandroussi C.

Liver Transpl. 2017 Mar;23(3):375-385. doi: 10.1002/lt.24689.


The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury.

Wang XM, Holz LE, Chowdhury S, Cordoba SP, Evans KA, Gall MG, Vieira de Ribeiro AJ, Zheng YZ, Levy MT, Yu DM, Yao TW, Polak N, Jolly CJ, Bertolino P, McCaughan GW, Gorrell MD.

Immunol Cell Biol. 2017 May;95(5):443-453. doi: 10.1038/icb.2016.116. Epub 2016 Nov 30.


Epidemiology and outcomes of primary sclerosing cholangitis with and without inflammatory bowel disease in an Australian cohort.

Liu K, Wang R, Kariyawasam V, Wells M, Strasser SI, McCaughan G, Corte C, Leong RW.

Liver Int. 2017 Mar;37(3):442-448. doi: 10.1111/liv.13328. Epub 2017 Jan 24.


The CD8 T-cell response during tolerance induction in liver transplantation.

Wong YC, McCaughan GW, Bowen DG, Bertolino P.

Clin Transl Immunology. 2016 Oct 14;5(10):e102. eCollection 2016 Oct. Review.


Accumulation of Deleterious Passenger Mutations Is Associated with the Progression of Hepatocellular Carcinoma.

Budzinska MA, Tu T, d'Avigdor WM, McCaughan GW, Luciani F, Shackel NA.

PLoS One. 2016 Sep 15;11(9):e0162586. doi: 10.1371/journal.pone.0162586. eCollection 2016.


2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.

Demetris AJ, Bellamy C, Hübscher SG, O'Leary J, Randhawa PS, Feng S, Neil D, Colvin RB, McCaughan G, Fung JJ, Del Bello A, Reinholt FP, Haga H, Adeyi O, Czaja AJ, Schiano T, Fiel MI, Smith ML, Sebagh M, Tanigawa RY, Yilmaz F, Alexander G, Baiocchi L, Balasubramanian M, Batal I, Bhan AK, Bucuvalas J, Cerski CTS, Charlotte F, de Vera ME, ElMonayeri M, Fontes P, Furth EE, Gouw ASH, Hafezi-Bakhtiari S, Hart J, Honsova E, Ismail W, Itoh T, Jhala NC, Khettry U, Klintmalm GB, Knechtle S, Koshiba T, Kozlowski T, Lassman CR, Lerut J, Levitsky J, Licini L, Liotta R, Mazariegos G, Minervini MI, Misdraji J, Mohanakumar T, Mölne J, Nasser I, Neuberger J, O'Neil M, Pappo O, Petrovic L, Ruiz P, Sağol Ö, Sanchez Fueyo A, Sasatomi E, Shaked A, Shiller M, Shimizu T, Sis B, Sonzogni A, Stevenson HL, Thung SN, Tisone G, Tsamandas AC, Wernerson A, Wu T, Zeevi A, Zen Y.

Am J Transplant. 2016 Oct;16(10):2816-2835. doi: 10.1111/ajt.13909. Epub 2016 Jul 14.


Programmed cell death-1 blockade in recurrent disseminated Ewing sarcoma.

McCaughan GJ, Fulham MJ, Mahar A, Soper J, Hong AM, Stalley PD, Tattersall MH, Bhadri VA.

J Hematol Oncol. 2016 Jun 3;9(1):48. doi: 10.1186/s13045-016-0278-x.


APASL consensus statements and recommendations for hepatitis C prevention, epidemiology, and laboratory testing.

Omata M, Kanda T, Wei L, Yu ML, Chuang WL, Ibrahim A, Lesmana CR, Sollano J, Kumar M, Jindal A, Sharma BC, Hamid SS, Dokmeci AK, Al-Mahtab M, McCaughan GW, Wasim J, Crawford DH, Kao JH, Yokosuka O, Lau GK, Sarin SK.

Hepatol Int. 2016 Sep;10(5):681-701. doi: 10.1007/s12072-016-9736-3. Epub 2016 May 26. Review.


Midkine Increases Diagnostic Yield in AFP Negative and NASH-Related Hepatocellular Carcinoma.

Vongsuvanh R, van der Poorten D, Iseli T, Strasser SI, McCaughan GW, George J.

PLoS One. 2016 May 24;11(5):e0155800. doi: 10.1371/journal.pone.0155800. eCollection 2016.

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