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Items: 30


Moderate-intensity aerobic and resistance exercise is safe and favorably influences body composition in patients with quiescent Inflammatory Bowel Disease: a randomized controlled cross-over trial.

Cronin O, Barton W, Moran C, Sheehan D, Whiston R, Nugent H, McCarthy Y, Molloy CB, O'Sullivan O, Cotter PD, Molloy MG, Shanahan F.

BMC Gastroenterol. 2019 Feb 12;19(1):29. doi: 10.1186/s12876-019-0952-x.


A Repeated-measures Case Series of Physiological Responses to a Transoceanic Rowing Race.

Keohane DM, Woods T, McCarthy Y, O'Connor P, Underwood S, Molloy MG.

Int J Sports Med. 2019 Mar;40(3):152-157. doi: 10.1055/a-0802-9140. Epub 2019 Jan 14.


Human epididymis protein 4 (HE4) levels inversely correlate with lung function improvement (delta FEV1) in cystic fibrosis patients receiving ivacaftor treatment.

Nagy B Jr, Bene Z, Fejes Z, Heltshe SL, Reid D, Ronan NJ, McCarthy Y, Smith D, Nagy A, Joseloff E, Balla G, Kappelmayer J, Macek M Jr, Bell SC, Plant BJ, Amaral MD, Balogh I.

J Cyst Fibros. 2019 Mar;18(2):271-277. doi: 10.1016/j.jcf.2018.08.013. Epub 2018 Sep 27.


Tissue and Bronchoalveolar Lavage Biomarkers in Idiopathic Pulmonary Fibrosis Patients on Pirfenidone.

Ronan N, Bennett DM, Khan KA, McCarthy Y, Dahly D, Bourke L, Chelliah A, Cavazza A, O'Regan K, Moloney F, Plant BJ, Henry MT.

Lung. 2018 Oct;196(5):543-552. doi: 10.1007/s00408-018-0140-8. Epub 2018 Jul 31.


Overexpression of RANK and M-CSFR in Monocytes of G551D-Bearing Patients with Cystic Fibrosis.

Velard F, Jourdain ML, Abdallah D, Jacquot J, Ronan N, McCarthy Y, Flanagan E, Plant B.

Am J Respir Crit Care Med. 2018 Oct 1;198(7):968-970. doi: 10.1164/rccm.201803-0415LE. No abstract available.


A pilot study demonstrating the altered gut microbiota functionality in stable adults with Cystic Fibrosis.

Fouhy F, Ronan NJ, O'Sullivan O, McCarthy Y, Walsh AM, Murphy DM, Daly M, Flanagan ET, Fleming C, McCarthy M, Shortt C, Eustace JA, Shanahan F, Rea MC, Ross RP, Stanton C, Plant BJ.

Sci Rep. 2017 Jul 27;7(1):6685. doi: 10.1038/s41598-017-06880-y.


Retraction for McCarthy et al., "The Ax21 Protein Is a Cell-Cell Signal That Regulates Virulence in the Nosocomial Pathogen Stenotrophomonas maltophilia".

McCarthy Y, Dow JM, Ryan RP.

J Bacteriol. 2017 Apr 25;199(10). pii: e00156-17. doi: 10.1128/JB.00156-17. Print 2017 May 15. No abstract available.


The DSF Family of Cell-Cell Signals: An Expanding Class of Bacterial Virulence Regulators.

Ryan RP, An SQ, Allan JH, McCarthy Y, Dow JM.

PLoS Pathog. 2015 Jul 16;11(7):e1004986. doi: 10.1371/journal.ppat.1004986. eCollection 2015 Jul. Review.


Haemophilus influenzae responds to glucocorticoids used in asthma therapy by modulation of biofilm formation and antibiotic resistance.

Earl CS, Keong TW, An SQ, Murdoch S, McCarthy Y, Garmendia J, Ward J, Dow JM, Yang L, O'Toole GA, Ryan RP.

EMBO Mol Med. 2015 Aug;7(8):1018-33. doi: 10.15252/emmm.201505088. Retraction in: EMBO Mol Med. 2018 Mar 12;:.


XbmR, a new transcription factor involved in the regulation of chemotaxis, biofilm formation and virulence in Xanthomonas citri subsp. citri.

Yaryura PM, Conforte VP, Malamud F, Roeschlin R, de Pino V, Castagnaro AP, McCarthy Y, Dow JM, Marano MR, Vojnov AA.

Environ Microbiol. 2015 Nov;17(11):4164-76. doi: 10.1111/1462-2920.12684. Epub 2014 Dec 17.


Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence.

An SQ, Caly DL, McCarthy Y, Murdoch SL, Ward J, Febrer M, Dow JM, Ryan RP.

PLoS Pathog. 2014 Oct 16;10(10):e1004429. doi: 10.1371/journal.ppat.1004429. eCollection 2014 Oct.


The PAS domain-containing histidine kinase RpfS is a second sensor for the diffusible signal factor of Xanthomonas campestris.

An SQ, Allan JH, McCarthy Y, Febrer M, Dow JM, Ryan RP.

Mol Microbiol. 2014 May;92(3):586-97. doi: 10.1111/mmi.12577. Epub 2014 Apr 2.


Microbiota and metabolite profiling reveal specific alterations in bacterial community structure and environment in the cystic fibrosis airway during exacerbation.

Twomey KB, Alston M, An SQ, O'Connell OJ, McCarthy Y, Swarbreck D, Febrer M, Dow JM, Plant BJ, Ryan RP.

PLoS One. 2013 Dec 17;8(12):e82432. doi: 10.1371/journal.pone.0082432. eCollection 2013.


Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre.

Bellini D, Caly DL, McCarthy Y, Bumann M, An SQ, Dow JM, Ryan RP, Walsh MA.

Mol Microbiol. 2014 Jan;91(1):26-38. doi: 10.1111/mmi.12447. Epub 2013 Nov 24.


A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis.

An SQ, Chin KH, Febrer M, McCarthy Y, Yang JG, Liu CL, Swarbreck D, Rogers J, Maxwell Dow J, Chou SH, Ryan RP.

EMBO J. 2013 Sep 11;32(18):2430-8. doi: 10.1038/emboj.2013.165. Epub 2013 Jul 23. Erratum in: EMBO J. 2013 Oct 16;32(20):2779-81.


Proteomics analysis of the regulatory role of Rpf/DSF cell-to-cell signaling system in the virulence of Xanthomonas campestris.

O'Connell A, An SQ, McCarthy Y, Schulte F, Niehaus K, He YQ, Tang JL, Ryan RP, Dow JM.

Mol Plant Microbe Interact. 2013 Oct;26(10):1131-7. doi: 10.1094/MPMI-05-13-0155-R. Erratum in: Mol Plant Microbe Interact. 2017 Feb;30(2):cx.


High-resolution transcriptional analysis of the regulatory influence of cell-to-cell signalling reveals novel genes that contribute to Xanthomonas phytopathogenesis.

An SQ, Febrer M, McCarthy Y, Tang DJ, Clissold L, Kaithakottil G, Swarbreck D, Tang JL, Rogers J, Dow JM, Ryan RP.

Mol Microbiol. 2013 Jun;88(6):1058-69. doi: 10.1111/mmi.12229. Epub 2013 Apr 26. Erratum in: Mol Microbiol. 2017 May;104(4):693-694.


RsmA regulates biofilm formation in Xanthomonas campestris through a regulatory network involving cyclic di-GMP and the Clp transcription factor.

Lu XH, An SQ, Tang DJ, McCarthy Y, Tang JL, Dow JM, Ryan RP.

PLoS One. 2012;7(12):e52646. doi: 10.1371/journal.pone.0052646. Epub 2012 Dec 21.


The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349.

Fazli M, McCarthy Y, Givskov M, Ryan RP, Tolker-Nielsen T.

Microbiologyopen. 2013 Feb;2(1):105-22. doi: 10.1002/mbo3.61. Epub 2012 Dec 25.


Dynamic complex formation between HD-GYP, GGDEF and PilZ domain proteins regulates motility in Xanthomonas campestris.

Ryan RP, McCarthy Y, Kiely PA, O'Connor R, Farah CS, Armitage JP, Dow JM.

Mol Microbiol. 2012 Nov;86(3):557-67. doi: 10.1111/mmi.12000. Epub 2012 Aug 31. Retraction in: Mol Microbiol. 2017 May;104(3):533.


An orphan chemotaxis sensor regulates virulence and antibiotic tolerance in the human pathogen Pseudomonas aeruginosa.

McLaughlin HP, Caly DL, McCarthy Y, Ryan RP, Dow JM.

PLoS One. 2012;7(8):e42205. doi: 10.1371/journal.pone.0042205. Epub 2012 Aug 1.


Bacterial cis-2-unsaturated fatty acids found in the cystic fibrosis airway modulate virulence and persistence of Pseudomonas aeruginosa.

Twomey KB, O'Connell OJ, McCarthy Y, Dow JM, O'Toole GA, Plant BJ, Ryan RP.

ISME J. 2012 May;6(5):939-50. doi: 10.1038/ismej.2011.167. Epub 2011 Dec 1.


The Ax21 protein is a cell-cell signal that regulates virulence in the nosocomial pathogen Stenotrophomonas maltophilia.

McCarthy Y, Dow JM, Ryan RP.

J Bacteriol. 2011 Nov;193(22):6375-8. doi: 10.1128/JB.05949-11. Epub 2011 Sep 9. Retraction in: J Bacteriol. 2017 Apr 25;199(10 ):.


A sensor kinase recognizing the cell-cell signal BDSF (cis-2-dodecenoic acid) regulates virulence in Burkholderia cenocepacia.

McCarthy Y, Yang L, Twomey KB, Sass A, Tolker-Nielsen T, Mahenthiralingam E, Dow JM, Ryan RP.

Mol Microbiol. 2010 Sep;77(5):1220-36. doi: 10.1111/j.1365-2958.2010.07285.x.


Cell-cell signal-dependent dynamic interactions between HD-GYP and GGDEF domain proteins mediate virulence in Xanthomonas campestris.

Ryan RP, McCarthy Y, Andrade M, Farah CS, Armitage JP, Dow JM.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5989-94. doi: 10.1073/pnas.0912839107. Epub 2010 Mar 15. Erratum in: Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1303.


The cAMP receptor-like protein CLP is a novel c-di-GMP receptor linking cell-cell signaling to virulence gene expression in Xanthomonas campestris.

Chin KH, Lee YC, Tu ZL, Chen CH, Tseng YH, Yang JM, Ryan RP, McCarthy Y, Dow JM, Wang AH, Chou SH.

J Mol Biol. 2010 Feb 26;396(3):646-62. doi: 10.1016/j.jmb.2009.11.076. Epub 2009 Dec 18.


Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia.

Ryan RP, McCarthy Y, Watt SA, Niehaus K, Dow JM.

J Bacteriol. 2009 Aug;191(15):5013-9. doi: 10.1128/JB.00473-09. Epub 2009 May 29.


HD-GYP domain proteins regulate biofilm formation and virulence in Pseudomonas aeruginosa.

Ryan RP, Lucey J, O'Donovan K, McCarthy Y, Yang L, Tolker-Nielsen T, Dow JM.

Environ Microbiol. 2009 May;11(5):1126-36. doi: 10.1111/j.1462-2920.2008.01842.x. Epub 2008 Dec 17. Erratum in: Environ Microbiol. 2016 Feb;18(2):736.


The role of PilZ domain proteins in the virulence of Xanthomonas campestris pv. campestris.

McCarthy Y, Ryan RP, O'Donovan K, He YQ, Jiang BL, Feng JX, Tang JL, Dow JM.

Mol Plant Pathol. 2008 Nov;9(6):819-24. doi: 10.1111/j.1364-3703.2008.00495.x.


Sibshops: an evaluation of an interagency model.

D'Arcy F, Flynn J, McCarthy Y, O'Connor C, Tierney E.

J Intellect Disabil. 2005 Mar;9(1):43-57.


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