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Items: 1 to 50 of 351

1.

Calcium Phosphate Nanoparticles-Based Systems for RNAi Delivery: Applications in Bone Tissue Regeneration.

Levingstone TJ, Herbaj S, Redmond J, McCarthy HO, Dunne NJ.

Nanomaterials (Basel). 2020 Jan 14;10(1). pii: E146. doi: 10.3390/nano10010146. Review.

2.

Acalabrutinib monotherapy in patients with Waldenström macroglobulinemia: a single-arm, multicentre, phase 2 study.

Owen RG, McCarthy H, Rule S, D'Sa S, Thomas SK, Tournilhac O, Forconi F, Kersten MJ, Zinzani PL, Iyengar S, Kothari J, Minnema MC, Kastritis E, Aurran-Schleinitz T, Cheson BD, Walter H, Greenwald D, Chen DY, Frigault MM, Hamdy A, Izumi R, Patel P, Wei H, Lee SK, Mittag D, Furman RR.

Lancet Haematol. 2019 Dec 19. pii: S2352-3026(19)30210-8. doi: 10.1016/S2352-3026(19)30210-8. [Epub ahead of print]

PMID:
31866281
3.

Moral cognition, the missing link between psychotic symptoms and acts of violence: a cross-sectional national forensic cohort study.

O'Reilly K, O'Connell P, O'Sullivan D, Corvin A, Sheerin J, O'Flynn P, Donohoe G, McCarthy H, Ambrosh D, O'Donnell M, Ryan A, Kennedy HG.

BMC Psychiatry. 2019 Dec 19;19(1):408. doi: 10.1186/s12888-019-2372-4.

4.

Molecular Analysis of Goodpasture's Disease Following Hematopoietic Stem Cell Transplant in a Pediatric Patient, Recalls the Conformeropathy of Wild-Type Anti-GBM Disease.

Gray PE, McCarthy H, Siggs OM, Saleem MA, O' Brien T, Frith K, Ziegler JB, Kitching AR, Fogo AB, Hudson BG, Pedchenko V.

Front Immunol. 2019 Nov 14;10:2659. doi: 10.3389/fimmu.2019.02659. eCollection 2019.

5.

FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer.

Annett S, Moore G, Short A, Marshall A, McCrudden C, Yakkundi A, Das S, McCluggage WG, Nelson L, Harley I, Moustafa N, Kennedy CJ, deFazio A, Brand A, Sharma R, Brennan D, O'Toole S, O'Leary J, Bates M, O'Riain C, O'Connor D, Furlong F, McCarthy H, Kissenpfennig A, McClements L, Robson T.

Br J Cancer. 2019 Nov 27. doi: 10.1038/s41416-019-0649-5. [Epub ahead of print]

PMID:
31772325
6.

Exploring the Potential of MicroRNA Let-7c as a Therapeutic for Prostate Cancer.

Mulholland EJ, Green WP, Buckley NE, McCarthy HO.

Mol Ther Nucleic Acids. 2019 Dec 6;18:927-937. doi: 10.1016/j.omtn.2019.09.031. Epub 2019 Oct 23. Review.

7.

MicroRNAs in Pancreatic Cancer: biomarkers, prognostic, and therapeutic modulators.

Daoud AZ, Mulholland EJ, Cole G, McCarthy HO.

BMC Cancer. 2019 Nov 21;19(1):1130. doi: 10.1186/s12885-019-6284-y.

8.

Delivery across the blood-brain barrier: nanomedicine for glioblastoma multiforme.

Jena L, McErlean E, McCarthy H.

Drug Deliv Transl Res. 2019 Nov 14. doi: 10.1007/s13346-019-00679-2. [Epub ahead of print] Review.

PMID:
31728942
9.

Delivery of RALA/siFKBPL nanoparticles via electrospun bilayer nanofibres: An innovative angiogenic therapy for wound repair.

Mulholland EJ, Ali A, Robson T, Dunne NJ, McCarthy HO.

J Control Release. 2019 Dec 28;316:53-65. doi: 10.1016/j.jconrel.2019.10.050. Epub 2019 Oct 30.

PMID:
31676385
10.

Solid lipid nanoparticle-based dissolving microneedles: A promising intradermal lymph targeting drug delivery system with potential for enhanced treatment of lymphatic filariasis.

Permana AD, Tekko IA, McCrudden MTC, Anjani QK, Ramadon D, McCarthy HO, Donnelly RF.

J Control Release. 2019 Dec 28;316:34-52. doi: 10.1016/j.jconrel.2019.10.004. Epub 2019 Oct 23.

11.

Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL: 5 years of follow-up from the phase 3 RESONATE-2 study.

Burger JA, Barr PM, Robak T, Owen C, Ghia P, Tedeschi A, Bairey O, Hillmen P, Coutre SE, Devereux S, Grosicki S, McCarthy H, Simpson D, Offner F, Moreno C, Dai S, Lal I, Dean JP, Kipps TJ.

Leukemia. 2019 Oct 18. doi: 10.1038/s41375-019-0602-x. [Epub ahead of print]

PMID:
31628428
12.

Nanocomposite-coated porous templates for engineered bone scaffolds: a parametric study of layer-by-layer assembly conditions.

Ziminska M, Chalanqui MJ, Chambers P, Acheson JG, McCarthy HO, Dunne NJ, Hamilton AR.

Biomed Mater. 2019 Sep 20;14(6):065008. doi: 10.1088/1748-605X/ab3b7b.

PMID:
31539364
13.

Comprehensive evaluation of a prospective Australian patient cohort with suspected genetic kidney disease undergoing clinical genomic testing: a study protocol.

Jayasinghe K, Stark Z, Patel C, Mallawaarachchi A, McCarthy H, Faull R, Chakera A, Sundaram M, Jose M, Kerr P, Wu Y, Wardrop L, Goranitis I, Best S, Martyn M, Quinlan C, Mallett AJ.

BMJ Open. 2019 Aug 5;9(8):e029541. doi: 10.1136/bmjopen-2019-029541.

14.

Incorporation of multi-walled carbon nanotubes to PMMA bone cement improves cytocompatibility and osseointegration.

Wang C, Yu B, Fan Y, Ormsby RW, McCarthy HO, Dunne N, Li X.

Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109823. doi: 10.1016/j.msec.2019.109823. Epub 2019 May 31.

PMID:
31349517
15.

Waist circumference centiles for UK South Asian children.

Shah M, Radia D, McCarthy HD.

Arch Dis Child. 2020 Jan;105(1):80-85. doi: 10.1136/archdischild-2018-315722. Epub 2019 Jul 18.

PMID:
31320360
16.

DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell antigen.

Cole G, Ali AA, McErlean E, Mulholland EJ, Short A, McCrudden CM, McCaffrey J, Robson T, Kett VL, Coulter JA, Dunne NJ, Donnelly RF, McCarthy HO.

Acta Biomater. 2019 Sep 15;96:480-490. doi: 10.1016/j.actbio.2019.07.003. Epub 2019 Jul 9.

PMID:
31299353
17.

Rapidly dissolving bilayer microneedle arrays - A minimally invasive transdermal drug delivery system for vitamin B12.

Ramöller IK, Tekko IA, McCarthy HO, Donnelly RF.

Int J Pharm. 2019 Jul 20;566:299-306. doi: 10.1016/j.ijpharm.2019.05.066. Epub 2019 May 28.

PMID:
31150773
18.

Combined Autologous Chondrocyte and Bone Marrow Mesenchymal Stromal Cell Implantation in the Knee: An 8-year Follow Up of Two First-In-Man Cases.

Wang J, Wright KT, Perry J, Tins B, Hopkins T, Hulme C, McCarthy HS, Brown A, Richardson JB.

Cell Transplant. 2019 Jul;28(7):924-931. doi: 10.1177/0963689719845328. Epub 2019 May 8.

19.

Quality of life in survivors of adult haematological malignancy.

Immanuel A, Hunt J, McCarthy H, van Teijlingen E, Sheppard ZA.

Eur J Cancer Care (Engl). 2019 Jul;28(4):e13067. doi: 10.1111/ecc.13067. Epub 2019 Apr 25.

PMID:
31020751
20.

Brain Imaging of the Cortex in ADHD: A Coordinated Analysis of Large-Scale Clinical and Population-Based Samples.

Hoogman M, Muetzel R, Guimaraes JP, Shumskaya E, Mennes M, Zwiers MP, Jahanshad N, Sudre G, Wolfers T, Earl EA, Soliva Vila JC, Vives-Gilabert Y, Khadka S, Novotny SE, Hartman CA, Heslenfeld DJ, Schweren LJS, Ambrosino S, Oranje B, de Zeeuw P, Chaim-Avancini TM, Rosa PGP, Zanetti MV, Malpas CB, Kohls G, von Polier GG, Seitz J, Biederman J, Doyle AE, Dale AM, van Erp TGM, Epstein JN, Jernigan TL, Baur-Streubel R, Ziegler GC, Zierhut KC, Schrantee A, Høvik MF, Lundervold AJ, Kelly C, McCarthy H, Skokauskas N, O'Gorman Tuura RL, Calvo A, Lera-Miguel S, Nicolau R, Chantiluke KC, Christakou A, Vance A, Cercignani M, Gabel MC, Asherson P, Baumeister S, Brandeis D, Hohmann S, Bramati IE, Tovar-Moll F, Fallgatter AJ, Kardatzki B, Schwarz L, Anikin A, Baranov A, Gogberashvili T, Kapilushniy D, Solovieva A, El Marroun H, White T, Karkashadze G, Namazova-Baranova L, Ethofer T, Mattos P, Banaschewski T, Coghill D, Plessen KJ, Kuntsi J, Mehta MA, Paloyelis Y, Harrison NA, Bellgrove MA, Silk TJ, Cubillo AI, Rubia K, Lazaro L, Brem S, Walitza S, Frodl T, Zentis M, Castellanos FX, Yoncheva YN, Haavik J, Reneman L, Conzelmann A, Lesch KP, Pauli P, Reif A, Tamm L, Konrad K, Oberwelland Weiss E, Busatto GF, Louza MR, Durston S, Hoekstra PJ, Oosterlaan J, Stevens MC, Ramos-Quiroga JA, Vilarroya O, Fair DA, Nigg JT, Thompson PM, Buitelaar JK, Faraone SV, Shaw P, Tiemeier H, Bralten J, Franke B.

Am J Psychiatry. 2019 Jul 1;176(7):531-542. doi: 10.1176/appi.ajp.2019.18091033. Epub 2019 Apr 24.

PMID:
31014101
21.

Longitudinal diffusion weighted imaging of limbic regions in patients with major depressive disorder after 6 years and partial to full remission.

Doolin K, Andrews S, Carballedo A, McCarthy H, O'Hanlon E, Tozzi L, Frodl T.

Psychiatry Res Neuroimaging. 2019 May 30;287:75-86. doi: 10.1016/j.pscychresns.2019.04.004. Epub 2019 Apr 12.

PMID:
31004996
22.

NAV-KIDS2 trial: protocol for a multi-centre, staggered randomised controlled trial of a patient navigator intervention in children with chronic kidney disease.

van Zwieten A, Caldwell P, Howard K, Tong A, Craig JC, Alexander S, Howell M, Armando TP, Hawley C, Jesudason S, Walker A, Mackie F, Kennedy S, McTaggart S, McCarthy H, Carter S, Kim S, Crafter S, Woodleigh R, Guha C, Wong G.

BMC Nephrol. 2019 Apr 18;20(1):134. doi: 10.1186/s12882-019-1325-y.

23.

FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4.

McClements L, Annett S, Yakkundi A, O'Rourke M, Valentine A, Moustafa N, Alqudah A, Simões BM, Furlong F, Short A, McIntosh SA, McCarthy HO, Clarke RB, Robson T.

BMC Cancer. 2019 Apr 11;19(1):351. doi: 10.1186/s12885-019-5500-0.

24.

Importance of sequential analysis of TP53 variation in patients with Waldenström Macroglobulinaemia.

Christian A, Davis Z, Walewska R, McCarthy H.

Br J Haematol. 2019 Aug;186(4):e73-e76. doi: 10.1111/bjh.15909. Epub 2019 Apr 9. No abstract available.

PMID:
30968394
25.

New HPLC-MS method for rapid and simultaneous quantification of doxycycline, diethylcarbamazine and albendazole metabolites in rat plasma and organs after concomitant oral administration.

Permana AD, Tekko IA, McCarthy HO, Donnelly RF.

J Pharm Biomed Anal. 2019 Jun 5;170:243-253. doi: 10.1016/j.jpba.2019.03.047. Epub 2019 Mar 26.

PMID:
30947125
26.

The Clinical Utility of the Genomic Prostate Score in Men with Very Low to Intermediate Risk Prostate Cancer.

Gaffney C, Golan R, Cantu MD, Scognamiglio T, McCarthy H, Mosquera JM, McClure TD, Barbieri CE, Robinson BD, Khani F.

J Urol. 2019 Jul;202(1):96-101. doi: 10.1097/JU.0000000000000170. Epub 2019 Jun 7.

PMID:
30933552
27.

Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues.

Gonzalez-Fernandez T, Rathan S, Hobbs C, Pitacco P, Freeman FE, Cunniffe GM, Dunne NJ, McCarthy HO, Nicolosi V, O'Brien FJ, Kelly DJ.

J Control Release. 2019 May 10;301:13-27. doi: 10.1016/j.jconrel.2019.03.006. Epub 2019 Mar 8.

PMID:
30853527
28.

Nutrition Education and Community Pharmacy: A First Exploration of Current Attitudes and Practices in Northern Ireland.

Douglas PL, McCarthy H, McCotter LE, Gallen S, McClean S, Gallagher AM, Ray S.

Pharmacy (Basel). 2019 Mar 5;7(1). pii: E27. doi: 10.3390/pharmacy7010027.

29.

Design, Formulation, and Evaluation of Novel Dissolving Microarray Patches Containing Rilpivirine for Intravaginal Delivery.

Mc Crudden MTC, Larrañeta E, Clark A, Jarrahian C, Rein-Weston A, Creelman B, Moyo Y, Lachau-Durand S, Niemeijer N, Williams P, McCarthy HO, Zehrung D, Donnelly RF.

Adv Healthc Mater. 2019 May;8(9):e1801510. doi: 10.1002/adhm.201801510. Epub 2019 Mar 6.

PMID:
30838804
30.

Hypoxia mimicking hydrogels to regulate the fate of transplanted stem cells.

Sathy BN, Daly A, Gonzalez-Fernandez T, Olvera D, Cunniffe G, McCarthy HO, Dunne N, Jeon O, Alsberg E, Donahue TLH, Kelly DJ.

Acta Biomater. 2019 Apr 1;88:314-324. doi: 10.1016/j.actbio.2019.02.042. Epub 2019 Feb 27.

PMID:
30825603
31.

Carbon dioxide and water vapor fluxes in winter wheat and tallgrass prairie in central Oklahoma.

Bajgain R, Xiao X, Basara J, Wagle P, Zhou Y, Mahan H, Gowda P, McCarthy HR, Northup B, Neel J, Steiner J.

Sci Total Environ. 2018 Dec 10;644:1511-1524. doi: 10.1016/j.scitotenv.2018.07.010. Epub 2018 Jul 23.

PMID:
30743864
32.

Interactive effects of adiposity and insulin resistance on the impaired lung function in asthmatic adults: cross-sectional analysis of NHANES data.

Sadeghimakki R, McCarthy HD.

Ann Hum Biol. 2019 Feb;46(1):56-62. doi: 10.1080/03014460.2019.1572223. Epub 2019 Mar 14.

PMID:
30712386
33.

Enhanced nanoparticle delivery exploiting tumour-responsive formulations.

Bennie LA, McCarthy HO, Coulter JA.

Cancer Nanotechnol. 2018;9(1):10. doi: 10.1186/s12645-018-0044-6. Epub 2018 Nov 21. Review.

34.

Influence of alginate backbone on efficacy of thermo-responsive alginate-g-P(NIPAAm) hydrogel as a vehicle for sustained and controlled gene delivery.

Chalanqui MJ, Pentlavalli S, McCrudden C, Chambers P, Ziminska M, Dunne N, McCarthy HO.

Mater Sci Eng C Mater Biol Appl. 2019 Feb 1;95:409-421. doi: 10.1016/j.msec.2017.09.003. Epub 2017 Sep 27.

PMID:
30573265
35.

Novel Hydrogel-Forming Microneedle Array for Intradermal Vaccination in Mice Using Ovalbumin as a Model Protein Antigen.

Courtenay AJ, Rodgers AM, McCrudden MTC, McCarthy HO, Donnelly RF.

Mol Pharm. 2019 Jan 7;16(1):118-127. doi: 10.1021/acs.molpharmaceut.8b00895. Epub 2018 Nov 27.

PMID:
30452868
36.

Design, formulation and evaluation of novel dissolving microarray patches containing a long-acting rilpivirine nanosuspension.

Mc Crudden MTC, Larrañeta E, Clark A, Jarrahian C, Rein-Weston A, Lachau-Durand S, Niemeijer N, Williams P, Haeck C, McCarthy HO, Zehrung D, Donnelly RF.

J Control Release. 2018 Dec 28;292:119-129. doi: 10.1016/j.jconrel.2018.11.002. Epub 2018 Nov 2.

37.

Development of three-dimensional printing polymer-ceramic scaffolds with enhanced compressive properties and tuneable resorption.

Zhou Z, Cunningham E, Lennon A, McCarthy HO, Buchanan F, Dunne N.

Mater Sci Eng C Mater Biol Appl. 2018 Dec 1;93:975-986. doi: 10.1016/j.msec.2018.08.048. Epub 2018 Aug 23.

PMID:
30274136
38.

Single-agent ibrutinib versus chemoimmunotherapy regimens for treatment-naïve patients with chronic lymphocytic leukemia: A cross-trial comparison of phase 3 studies.

Robak T, Burger JA, Tedeschi A, Barr PM, Owen C, Bairey O, Hillmen P, Simpson D, Grosicki S, Devereux S, McCarthy H, Coutre SE, Quach H, Gaidano G, Maslyak Z, Stevens DA, Moreno C, Gill DS, Flinn IW, Gribben JG, Mokatrin A, Cheng M, Styles L, James DF, Kipps TJ, Ghia P.

Am J Hematol. 2018 Nov;93(11):1402-1410. doi: 10.1002/ajh.25259. Epub 2018 Oct 9.

39.

Magnetic Resonance Imaging Parameters at 1 Year Correlate With Clinical Outcomes Up to 17 Years After Autologous Chondrocyte Implantation.

McCarthy HS, McCall IW, Williams JM, Mennan C, Dugard MN, Richardson JB, Roberts S.

Orthop J Sports Med. 2018 Aug 7;6(8):2325967118788280. doi: 10.1177/2325967118788280. eCollection 2018 Aug.

40.

Guideline for the treatment of chronic lymphocytic leukaemia: A British Society for Haematology Guideline.

Schuh AH, Parry-Jones N, Appleby N, Bloor A, Dearden CE, Fegan C, Follows G, Fox CP, Iyengar S, Kennedy B, McCarthy H, Parry HM, Patten P, Pettitt AR, Ringshausen I, Walewska R, Hillmen P.

Br J Haematol. 2018 Aug;182(3):344-359. doi: 10.1111/bjh.15460. Epub 2018 Jul 15. No abstract available.

PMID:
30009455
41.

Microneedle-Mediated Transdermal Delivery of Bevacizumab.

Courtenay AJ, McCrudden MTC, McAvoy KJ, McCarthy HO, Donnelly RF.

Mol Pharm. 2018 Aug 6;15(8):3545-3556. doi: 10.1021/acs.molpharmaceut.8b00544. Epub 2018 Jul 24.

PMID:
29996645
42.

Hydrogel-forming microneedles enhance transdermal delivery of metformin hydrochloride.

Migdadi EM, Courtenay AJ, Tekko IA, McCrudden MTC, Kearney MC, McAlister E, McCarthy HO, Donnelly RF.

J Control Release. 2018 Sep 10;285:142-151. doi: 10.1016/j.jconrel.2018.07.009. Epub 2018 Jul 7.

43.

Evapotranspiration and water yield of a pine-broadleaf forest are not altered by long-term atmospheric [CO2 ] enrichment under native or enhanced soil fertility.

Ward EJ, Oren R, Seok Kim H, Kim D, Tor-Ngern P, Ewers BE, McCarthy HR, Oishi AC, Pataki DE, Palmroth S, Phillips NG, Schäfer KVR.

Glob Chang Biol. 2018 Oct;24(10):4841-4856. doi: 10.1111/gcb.14363. Epub 2018 Aug 1.

PMID:
29949220
44.

Gene therapy with RALA/iNOS composite nanoparticles significantly enhances survival in a model of metastatic prostate cancer.

McCrudden CM, McBride JW, McCaffrey J, McErlean EM, Dunne NJ, Kett VL, Coulter JA, Robson T, McCarthy HO.

Cancer Nanotechnol. 2018;9(1):5. doi: 10.1186/s12645-018-0040-x. Epub 2018 Jun 1.

45.

Sustained efficacy and detailed clinical follow-up of first-line ibrutinib treatment in older patients with chronic lymphocytic leukemia: extended phase 3 results from RESONATE-2.

Barr PM, Robak T, Owen C, Tedeschi A, Bairey O, Bartlett NL, Burger JA, Hillmen P, Coutre S, Devereux S, Grosicki S, McCarthy H, Li J, Simpson D, Offner F, Moreno C, Zhou C, Styles L, James D, Kipps TJ, Ghia P.

Haematologica. 2018 Sep;103(9):1502-1510. doi: 10.3324/haematol.2018.192328. Epub 2018 Jun 7.

46.

Intradermal Delivery of a Near-Infrared Photosensitizer Using Dissolving Microneedle Arrays.

Hamdan IMN, Tekko IA, Matchett KB, Arnaut LG, Silva CS, McCarthy HO, Donnelly RF.

J Pharm Sci. 2018 Sep;107(9):2439-2450. doi: 10.1016/j.xphs.2018.05.017. Epub 2018 Jun 1.

PMID:
29864428
47.

Dissolving polymeric microneedle arrays for enhanced site-specific acyclovir delivery.

Pamornpathomkul B, Ngawhirunpat T, Tekko IA, Vora L, McCarthy HO, Donnelly RF.

Eur J Pharm Sci. 2018 Aug 30;121:200-209. doi: 10.1016/j.ejps.2018.05.009. Epub 2018 May 16.

PMID:
29777854
48.

Treatment of recurrent focal segmental glomerulosclerosis post-kidney transplantation in Australian and New Zealand children: A retrospective cohort study.

Francis A, Didsbury M, McCarthy H, Kara T.

Pediatr Transplant. 2018 Aug;22(5):e13185. doi: 10.1111/petr.13185. Epub 2018 Apr 19.

PMID:
29676031
49.

Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential.

Mennan C, Garcia J, McCarthy H, Owen S, Perry J, Wright K, Banerjee R, Richardson JB, Roberts S.

Cartilage. 2019 Oct;10(4):467-479. doi: 10.1177/1947603518769714. Epub 2018 Apr 19.

PMID:
29671342
50.

DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable microneedle system.

Cole G, Ali AA, McCrudden CM, McBride JW, McCaffrey J, Robson T, Kett VL, Dunne NJ, Donnelly RF, McCarthy HO.

Eur J Pharm Biopharm. 2018 Jun;127:288-297. doi: 10.1016/j.ejpb.2018.02.029. Epub 2018 Mar 3.

PMID:
29510205

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