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Genetic predisposition for increased red blood cell distribution width is an early risk factor for cardiovascular and renal comorbidities.

Cheng X, Mell B, Alimadadi A, Galla S, McCarthy CG, Chakraborty S, Basrur V, Joe B.

Dis Model Mech. 2020 Apr 3. pii: dmm.044081. doi: 10.1242/dmm.044081. [Epub ahead of print]


Toll-like receptor 9 regulates metabolic profile and contributes to obesity-induced benign prostatic hyperplasia in mice.

Calmasini FB, McCarthy CG, Wenceslau CF, Priviero FBM, Antunes E, Webb RC.

Pharmacol Rep. 2020 Feb;72(1):179-187. doi: 10.1007/s43440-019-00010-3. Epub 2020 Jan 8.


Microbiota are critical for vascular physiology: Germ-free status weakens contractility and induces sex-specific vascular remodeling in mice.

Edwards JM, Roy S, Tomcho JC, Schreckenberger ZJ, Chakraborty S, Bearss NR, Saha P, McCarthy CG, Vijay-Kumar M, Joe B, Wenceslau CF.

Vascul Pharmacol. 2020 Feb - Mar;125-126:106633. doi: 10.1016/j.vph.2019.106633. Epub 2019 Dec 13.


Reconstitution of autophagy ameliorates vascular function and arterial stiffening in spontaneously hypertensive rats.

McCarthy CG, Wenceslau CF, Calmasini FB, Klee NS, Brands MW, Joe B, Webb RC.

Am J Physiol Heart Circ Physiol. 2019 Nov 1;317(5):H1013-H1027. doi: 10.1152/ajpheart.00227.2019. Epub 2019 Aug 30.


Whole Genome Sequence of the Commercially Relevant Mushroom Strain Agaricus bisporus var. bisporus ARP23.

O'Connor E, McGowan J, McCarthy CGP, Amini A, Grogan H, Fitzpatrick DA.

G3 (Bethesda). 2019 Oct 7;9(10):3057-3066. doi: 10.1534/g3.119.400563.


TRPM8 channel activation triggers relaxation of pudendal artery with increased sensitivity in the hypertensive rats.

Silva DF, Wenceslau CF, Mccarthy CG, Szasz T, Ogbi S, Webb RC.

Pharmacol Res. 2019 Sep;147:104329. doi: 10.1016/j.phrs.2019.104329. Epub 2019 Jul 21.


Pangloss: A Tool for Pan-Genome Analysis of Microbial Eukaryotes.

McCarthy CGP, Fitzpatrick DA.

Genes (Basel). 2019 Jul 10;10(7). pii: E521. doi: 10.3390/genes10070521.


Targeting Endothelial Barrier Dysfunction Caused by Circulating Bacterial and Mitochondrial N-Formyl Peptides With Deformylase.

Martinez-Quinones P, Komic A, McCarthy CG, Webb RC, Wenceslau CF.

Front Immunol. 2019 Jun 6;10:1270. doi: 10.3389/fimmu.2019.01270. eCollection 2019.


Antibiotic resistomes of healthy pig faecal metagenomes.

Joyce A, McCarthy CGP, Murphy S, Walsh F.

Microb Genom. 2019 May;5(5). doi: 10.1099/mgen.0.000272. Epub 2019 May 15.


Novel Contributors and Mechanisms of Cellular Senescence in Hypertension-Associated Premature Vascular Aging.

McCarthy CG, Wenceslau CF, Webb RC, Joe B.

Am J Hypertens. 2019 Jul 17;32(8):709-719. doi: 10.1093/ajh/hpz052.


Pan-genome analyses of model fungal species.

McCarthy CGP, Fitzpatrick DA.

Microb Genom. 2019 Feb;5(2). doi: 10.1099/mgen.0.000243. Epub 2019 Feb 4.


Paying the Toll for Inflammation.

McCarthy CG, Goulopoulou S, Webb RC.

Hypertension. 2019 Mar;73(3):514-521. doi: 10.1161/HYPERTENSIONAHA.118.11782. Review. No abstract available.


Formyl peptide receptor-1 activation exerts a critical role for the dynamic plasticity of arteries via actin polymerization.

Wenceslau CF, McCarthy CG, Szasz T, Calmasini FB, Mamenko M, Webb RC.

Pharmacol Res. 2019 Mar;141:276-290. doi: 10.1016/j.phrs.2019.01.015. Epub 2019 Jan 10.


Evolutionary, structural and functional analysis of the caleosin/peroxygenase gene family in the Fungi.

Rahman F, Hassan M, Hanano A, Fitzpatrick DA, McCarthy CGP, Murphy DJ.

BMC Genomics. 2018 Dec 28;19(1):976. doi: 10.1186/s12864-018-5334-1.


Urothelial Senescence in the Pathophysiology of Diabetic Bladder Dysfunction-A Novel Hypothesis.

Klee NS, McCarthy CG, Lewis S, McKenzie JL, Vincent JE, Webb RC.

Front Surg. 2018 Dec 4;5:72. doi: 10.3389/fsurg.2018.00072. eCollection 2018.


B lymphoma Moloney murine leukemia virus insertion region 1 homolog: the Janus-faced polycomb protein that will break your heart.

McCarthy CG, Wenceslau CF, Joe B.

Am J Physiol Heart Circ Physiol. 2019 Feb 1;316(2):H257-H259. doi: 10.1152/ajpheart.00726.2018. Epub 2018 Nov 21. No abstract available.


Increase in soluble protein oligomers triggers the innate immune system promoting inflammation and vascular dysfunction in the pathogenesis of sepsis.

Komic A, Martinez-Quinones P, McCarthy CG, Webb RC, Wenceslau CF.

Clin Sci (Lond). 2018 Jul 18;132(13):1433-1438. doi: 10.1042/CS20180368. Print 2018 Jul 18. Review.


Genome analysis of the yeast Diutina catenulata, a member of the Debaryomycetaceae/Metschnikowiaceae (CTG-Ser) clade.

O'Brien CE, McCarthy CGP, Walshe AE, Shaw DR, Sumski DA, Krassowski T, Fitzpatrick DA, Butler G.

PLoS One. 2018 Jun 26;13(6):e0198957. doi: 10.1371/journal.pone.0198957. eCollection 2018.


Adopting an Orphan: How Could GRP35 Contribute to Angiotensin II-Dependent Hypertension?

McCarthy CG, Wenceslau CF.

Am J Hypertens. 2018 Aug 3;31(9):973-975. doi: 10.1093/ajh/hpy090. No abstract available.


To Be, or Nox to Be, Endoplasmic Reticulum Stress in Hypertension.

Wenceslau CF, McCarthy CG, Webb RC.

Hypertension. 2018 Jul;72(1):59-60. doi: 10.1161/HYPERTENSIONAHA.118.10940. Epub 2018 May 29. No abstract available.


Hypertension Induced Morphological and Physiological Changes in Cells of the Arterial Wall.

Martinez-Quinones P, McCarthy CG, Watts SW, Klee NS, Komic A, Calmasini FB, Priviero F, Warner A, Chenghao Y, Wenceslau CF.

Am J Hypertens. 2018 Sep 11;31(10):1067-1078. doi: 10.1093/ajh/hpy083. Review.


Toll-Like Receptor 9-Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells.

McCarthy CG, Wenceslau CF, Ogbi S, Szasz T, Webb RC.

J Pharmacol Exp Ther. 2018 Apr;365(1):60-71. doi: 10.1124/jpet.117.245746. Epub 2018 Jan 18.


Effect of myostatin deletion on cardiac and microvascular function.

Butcher JT, Ali MI, Ma MW, McCarthy CG, Islam BN, Fox LG, Mintz JD, Larion S, Fulton DJ, Stepp DW.

Physiol Rep. 2017 Dec;5(23). doi: 10.14814/phy2.13525.


Multiple Approaches to Phylogenomic Reconstruction of the Fungal Kingdom.

McCarthy CGP, Fitzpatrick DA.

Adv Genet. 2017;100:211-266. doi: 10.1016/bs.adgen.2017.09.006. Epub 2017 Nov 6.


Protein kinase Cα deletion causes hypotension and decreased vascular contractility.

Wynne BM, McCarthy CG, Szasz T, Molina PA, Chapman AB, Webb RC, Klein JD, Hoover RS.

J Hypertens. 2018 Mar;36(3):510-519. doi: 10.1097/HJH.0000000000001596.


Out of the frying pan and into the fire: damage-associated molecular patterns and cardiovascular toxicity following cancer therapy.

Klee NS, McCarthy CG, Martinez-Quinones P, Webb RC.

Ther Adv Cardiovasc Dis. 2017 Nov;11(11):297-317. doi: 10.1177/1753944717729141. Epub 2017 Sep 15. Review.


Peritoneal cavity lavage reduces the presence of mitochondrial damage associated molecular patterns in open abdomen patients.

Martinez-Quinones PA, McCarthy CG, Mentzer CJ, Wenceslau CF, Holsten SB, Webb RC, O'Malley K.

J Trauma Acute Care Surg. 2017 Dec;83(6):1062-1065. doi: 10.1097/TA.0000000000001676.


Phylogenomic Reconstruction of the Oomycete Phylogeny Derived from 37 Genomes.

McCarthy CGP, Fitzpatrick DA.

mSphere. 2017 Apr 12;2(2). pii: e00095-17. doi: 10.1128/mSphere.00095-17. eCollection 2017 Mar-Apr.


Autoimmune therapeutic chloroquine lowers blood pressure and improves endothelial function in spontaneously hypertensive rats.

McCarthy CG, Wenceslau CF, Goulopoulou S, Ogbi S, Matsumoto T, Webb RC.

Pharmacol Res. 2016 Nov;113(Pt A):384-394. doi: 10.1016/j.phrs.2016.09.008. Epub 2016 Sep 14.


Systematic Search for Evidence of Interdomain Horizontal Gene Transfer from Prokaryotes to Oomycete Lineages.

McCarthy CG, Fitzpatrick DA.

mSphere. 2016 Sep 14;1(5). pii: e00195-16. doi: 10.1128/mSphere.00195-16. eCollection 2016 Sep-Oct.


Chloroquine Suppresses the Development of Hypertension in Spontaneously Hypertensive Rats.

McCarthy CG, Wenceslau CF, Goulopoulou S, Baban B, Matsumoto T, Webb RC.

Am J Hypertens. 2017 Feb;30(2):173-181. doi: 10.1093/ajh/hpw113. Epub 2016 Sep 13.


Formyl Peptide Receptor Activation Elicits Endothelial Cell Contraction and Vascular Leakage.

Wenceslau CF, McCarthy CG, Webb RC.

Front Immunol. 2016 Aug 2;7:297. doi: 10.3389/fimmu.2016.00297. eCollection 2016.


Mitochondrial N-formyl peptides cause airway contraction and lung neutrophil infiltration via formyl peptide receptor activation.

Wenceslau CF, Szasz T, McCarthy CG, Baban B, NeSmith E, Webb RC.

Pulm Pharmacol Ther. 2016 Apr;37:49-56. doi: 10.1016/j.pupt.2016.02.005. Epub 2016 Feb 23.


Exposure to stimulatory CpG oligonucleotides during gestation induces maternal hypertension and excess vasoconstriction in pregnant rats.

Goulopoulou S, Wenceslau CF, McCarthy CG, Matsumoto T, Webb RC.

Am J Physiol Heart Circ Physiol. 2016 Apr 15;310(8):H1015-25. doi: 10.1152/ajpheart.00834.2015. Epub 2016 Feb 12.


Toll-like Receptors in the Vascular System: Sensing the Dangers Within.

Goulopoulou S, McCarthy CG, Webb RC.

Pharmacol Rev. 2016 Jan;68(1):142-67. doi: 10.1124/pr.114.010090. Review.


The toll of the gridiron: damage-associated molecular patterns and hypertension in American football.

McCarthy CG, Webb RC.

FASEB J. 2016 Jan;30(1):34-40. doi: 10.1096/fj.15-279588. Epub 2015 Aug 27. Review.


Circulating mitochondrial DNA and Toll-like receptor 9 are associated with vascular dysfunction in spontaneously hypertensive rats.

McCarthy CG, Wenceslau CF, Goulopoulou S, Ogbi S, Baban B, Sullivan JC, Matsumoto T, Webb RC.

Cardiovasc Res. 2015 Jul 1;107(1):119-30. doi: 10.1093/cvr/cvv137. Epub 2015 Apr 24.


Mitochondrial N-formyl peptides induce cardiovascular collapse and sepsis-like syndrome.

Wenceslau CF, McCarthy CG, Szasz T, Goulopoulou S, Webb RC.

Am J Physiol Heart Circ Physiol. 2015 Apr 1;308(7):H768-77. doi: 10.1152/ajpheart.00779.2014. Epub 2015 Jan 30.


Lipoxin A4 mediates aortic contraction via RHOA/RHO kinase, endothelial dysfunction and reactive oxygen species.

Wenceslau CF, McCarthy CG, Szasz T, Webb RC.

J Vasc Res. 2014;51(6):407-17. doi: 10.1159/000371490. Epub 2015 Jan 21.


Influence of acute exercise of varying intensity and duration on postprandial oxidative stress.

Canale RE, Farney TM, McCarthy CG, Bloomer RJ.

Eur J Appl Physiol. 2014 Sep;114(9):1913-24. doi: 10.1007/s00421-014-2912-z. Epub 2014 Jun 8.


Mitochondrial damage-associated molecular patterns and vascular function.

Wenceslau CF, McCarthy CG, Szasz T, Spitler K, Goulopoulou S, Webb RC; Working Group on DAMPs in Cardiovascular Disease.

Eur Heart J. 2014 May;35(18):1172-7. doi: 10.1093/eurheartj/ehu047. Epub 2014 Feb 25. Review.


Toll-like receptors and damage-associated molecular patterns: novel links between inflammation and hypertension.

McCarthy CG, Goulopoulou S, Wenceslau CF, Spitler K, Matsumoto T, Webb RC.

Am J Physiol Heart Circ Physiol. 2014 Jan 15;306(2):H184-96. doi: 10.1152/ajpheart.00328.2013. Epub 2013 Oct 25. Review.


Cissus quadrangularis reduces joint pain in exercise-trained men: a pilot study.

Bloomer RJ, Farney TM, McCarthy CG, Lee SR.

Phys Sportsmed. 2013 Sep;41(3):29-35. doi: 10.3810/psm.2013.09.2021.


Mitochondrial-derived N-formyl peptides: novel links between trauma, vascular collapse and sepsis.

Wenceslau CF, McCarthy CG, Goulopoulou S, Szasz T, NeSmith EG, Webb RC.

Med Hypotheses. 2013 Oct;81(4):532-5. doi: 10.1016/j.mehy.2013.06.026. Epub 2013 Jul 24.


High-fat feeding, but not strenuous exercise, increases blood oxidative stress in trained men.

McCarthy CG, Farney TM, Canale RE, Dessoulavy ME, Bloomer RJ.

Appl Physiol Nutr Metab. 2013 Jan;38(1):33-41. doi: 10.1139/apnm-2012-0222. Epub 2013 Jan 1.


Impact of oral ubiquinol on blood oxidative stress and exercise performance.

Bloomer RJ, Canale RE, McCarthy CG, Farney TM.

Oxid Med Cell Longev. 2012;2012:465020. doi: 10.1155/2012/465020. Epub 2012 Aug 23.


A dietary supplement containing chlorophytum borivilianum and velvet bean improves sleep quality in men and women.

McCarthy CG, Alleman RJ, Bell ZW, Bloomer RJ.

Integr Med Insights. 2012;7:7-14. doi: 10.4137/IMI.S9720. Epub 2012 Jun 19.


Absence of blood oxidative stress in trained men after strenuous exercise.

Farney TM, McCarthy CG, Canale RE, Schilling BK, Whitehead PN, Bloomer RJ.

Med Sci Sports Exerc. 2012 Oct;44(10):1855-63. doi: 10.1249/MSS.0b013e3182592575.


A finished dietary supplement stimulates lipolysis and metabolic rate in young men and women.

McCarthy CG, Farney TM, Canale RE, Alleman RJ Jr, Bloomer RJ.

Nutr Metab Insights. 2011 Dec 6;5:23-31. doi: 10.4137/NMI.S8567. Print 2012.


Biochemical and anthropometric effects of a weight loss dietary supplement in healthy men and women.

McCarthy CG, Canale RE, Alleman RJ Jr, Reed JP, Bloomer RJ.

Nutr Metab Insights. 2011 Dec 6;5:13-22. doi: 10.4137/NMI.S8566. Print 2012.

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