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Items: 1 to 50 of 72

1.

Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.

Ashraf U, Tengo L, Le Corre L, Fournier G, Busca P, McCarthy AA, Rameix-Welti MA, Gravier-Pelletier C, Ruigrok RWH, Jacob Y, Vidalain PO, Pietrancosta N, Crépin T, Naffakh N.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10968-10977. doi: 10.1073/pnas.1901214116. Epub 2019 May 10.

PMID:
31076555
2.

MXCuBE2: the dawn of MXCuBE Collaboration.

Oscarsson M, Beteva A, Flot D, Gordon E, Guijarro M, Leonard G, McSweeney S, Monaco S, Mueller-Dieckmann C, Nanao M, Nurizzo D, Popov AN, von Stetten D, Svensson O, Rey-Bakaikoa V, Chado I, Chavas LMG, Gadea L, Gourhant P, Isabet T, Legrand P, Savko M, Sirigu S, Shepard W, Thompson A, Mueller U, Nan J, Eguiraun M, Bolmsten F, Nardella A, Milàn-Otero A, Thunnissen M, Hellmig M, Kastner A, Schmuckermaier L, Gerlach M, Feiler C, Weiss MS, Bowler MW, Gobbo A, Papp G, Sinoir J, McCarthy AA, Karpics I, Nikolova M, Bourenkov G, Schneider T, Andreu J, Cuní G, Juanhuix J, Boer R, Fogh R, Keller P, Flensburg C, Paciorek W, Vonrhein C, Bricogne G, de Sanctis D.

J Synchrotron Radiat. 2019 Mar 1;26(Pt 2):393-405. doi: 10.1107/S1600577519001267. Epub 2019 Feb 22.

3.

Structural Principles in Robo Activation and Auto-inhibition.

Barak R, Yom-Tov G, Guez-Haddad J, Gasri-Plotnitsky L, Maimon R, Cohen-Berkman M, McCarthy AA, Perlson E, Henis-Korenblit S, Isupov MN, Opatowsky Y.

Cell. 2019 Apr 4;177(2):272-285.e16. doi: 10.1016/j.cell.2019.02.004. Epub 2019 Mar 7.

PMID:
30853216
4.

Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX.

De I, Chittock EC, Grötsch H, Miller TCR, McCarthy AA, Müller CW.

Structure. 2019 Mar 5;27(3):528-536.e4. doi: 10.1016/j.str.2018.11.013. Epub 2019 Jan 10.

PMID:
30639226
5.

Calibration of rotation axes for multi-axis goniometers in macromolecular crystallography.

White KI, Bugris V, McCarthy AA, Ravelli RBG, Csankó K, Cassetta A, Brockhauser S.

J Appl Crystallogr. 2018 Sep 13;51(Pt 5):1421-1427. doi: 10.1107/S1600576718010956. eCollection 2018 Oct 1.

6.

Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.

Mendel M, Chen KM, Homolka D, Gos P, Pandey RR, McCarthy AA, Pillai RS.

Mol Cell. 2018 Sep 20;71(6):986-1000.e11. doi: 10.1016/j.molcel.2018.08.004. Epub 2018 Sep 6.

7.

ID30B - a versatile beamline for macromolecular crystallography experiments at the ESRF.

McCarthy AA, Barrett R, Beteva A, Caserotto H, Dobias F, Felisaz F, Giraud T, Guijarro M, Janocha R, Khadrouche A, Lentini M, Leonard GA, Lopez Marrero M, Malbet-Monaco S, McSweeney S, Nurizzo D, Papp G, Rossi C, Sinoir J, Sorez C, Surr J, Svensson O, Zander U, Cipriani F, Theveneau P, Mueller-Dieckmann C.

J Synchrotron Radiat. 2018 Jul 1;25(Pt 4):1249-1260. doi: 10.1107/S1600577518007166. Epub 2018 Jun 27.

8.

A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model.

Skubák P, Araç D, Bowler MW, Correia AR, Hoelz A, Larsen S, Leonard GA, McCarthy AA, McSweeney S, Mueller-Dieckmann C, Otten H, Salzman G, Pannu NS.

IUCrJ. 2018 Jan 25;5(Pt 2):166-171. doi: 10.1107/S2052252517017961. eCollection 2018 Mar 1.

9.

Robo1 Forms a Compact Dimer-of-Dimers Assembly.

Aleksandrova N, Gutsche I, Kandiah E, Avilov SV, Petoukhov MV, Seiradake E, McCarthy AA.

Structure. 2018 Feb 6;26(2):320-328.e4. doi: 10.1016/j.str.2017.12.003. Epub 2018 Jan 4.

10.

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites.

Simon B, Huart AS, Temmerman K, Vahokoski J, Mertens HD, Komadina D, Hoffmann JE, Yumerefendi H, Svergun DI, Kursula P, Schultz C, McCarthy AA, Hart DJ, Wilmanns M.

Structure. 2016 Jun 7;24(6):851-61. doi: 10.1016/j.str.2016.03.020. Epub 2016 Apr 28.

11.

PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway.

Yang Z, Chen KM, Pandey RR, Homolka D, Reuter M, Janeiro BK, Sachidanandam R, Fauvarque MO, McCarthy AA, Pillai RS.

Mol Cell. 2016 Jan 7;61(1):138-52. doi: 10.1016/j.molcel.2015.11.009. Epub 2015 Dec 6.

12.

Asymmetric ring structure of Vps4 required for ESCRT-III disassembly.

Caillat C, Macheboeuf P, Wu Y, McCarthy AA, Boeri-Erba E, Effantin G, Göttlinger HG, Weissenhorn W, Renesto P.

Nat Commun. 2015 Dec 3;6:8781. doi: 10.1038/ncomms9781.

13.

MeshAndCollect: an automated multi-crystal data-collection workflow for synchrotron macromolecular crystallography beamlines.

Zander U, Bourenkov G, Popov AN, de Sanctis D, Svensson O, McCarthy AA, Round E, Gordeliy V, Mueller-Dieckmann C, Leonard GA.

Acta Crystallogr D Biol Crystallogr. 2015 Nov;71(Pt 11):2328-43. doi: 10.1107/S1399004715017927. Epub 2015 Oct 31.

14.

Metazoan Maelstrom is an RNA-binding protein that has evolved from an ancient nuclease active in protists.

Chen KM, Campbell E, Pandey RR, Yang Z, McCarthy AA, Pillai RS.

RNA. 2015 May;21(5):833-9. doi: 10.1261/rna.049437.114. Epub 2015 Mar 16.

15.

Conducting facilities assessments. Determining where capital dollars should be invested.

McCarthy AA.

Health Facil Manage. 2014 Aug;27(8):30-4. No abstract available.

PMID:
25269329
16.

Protein assembly mediated by sulfonatocalix[4]arene.

McGovern RE, McCarthy AA, Crowley PB.

Chem Commun (Camb). 2014 Sep 18;50(72):10412-5. doi: 10.1039/c4cc04897k.

PMID:
25068633
17.

The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs.

Cora E, Pandey RR, Xiol J, Taylor J, Sachidanandam R, McCarthy AA, Pillai RS.

RNA. 2014 Jun;20(6):773-81. doi: 10.1261/rna.044701.114. Epub 2014 Apr 22.

18.

The use of a mini-κ goniometer head in macromolecular crystallography diffraction experiments.

Brockhauser S, Ravelli RB, McCarthy AA.

Acta Crystallogr D Biol Crystallogr. 2013 Jul;69(Pt 7):1241-51. doi: 10.1107/S0907444913003880. Epub 2013 Jun 15.

19.

Automatic processing of macromolecular crystallography X-ray diffraction data at the ESRF.

Monaco S, Gordon E, Bowler MW, Delagenière S, Guijarro M, Spruce D, Svensson O, McSweeney SM, McCarthy AA, Leonard G, Nanao MH.

J Appl Crystallogr. 2013 Jun 1;46(Pt 3):804-810. Epub 2013 May 15.

20.

The use of workflows in the design and implementation of complex experiments in macromolecular crystallography.

Brockhauser S, Svensson O, Bowler MW, Nanao M, Gordon E, Leal RM, Popov A, Gerring M, McCarthy AA, Gotz A.

Acta Crystallogr D Biol Crystallogr. 2012 Aug;68(Pt 8):975-84. doi: 10.1107/S090744491201863X. Epub 2012 Jul 17.

21.

A structural basis for the biosynthesis of the major chlorogenic acids found in coffee.

Lallemand LA, Zubieta C, Lee SG, Wang Y, Acajjaoui S, Timmins J, McSweeney S, Jez JM, McCarthy JG, McCarthy AA.

Plant Physiol. 2012 Sep;160(1):249-60. doi: 10.1104/pp.112.202051. Epub 2012 Jul 20.

22.

Purification, crystallization and preliminary X-ray diffraction analysis of a hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyltransferase (HCT) from Coffea canephora involved in chlorogenic acid biosynthesis.

Lallemand LA, McCarthy JG, McSweeney S, McCarthy AA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):824-8. doi: 10.1107/S1744309112019082. Epub 2012 Jun 28.

23.

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA.

Kowalinski E, Lunardi T, McCarthy AA, Louber J, Brunel J, Grigorov B, Gerlier D, Cusack S.

Cell. 2011 Oct 14;147(2):423-35. doi: 10.1016/j.cell.2011.09.039.

24.

Translation calibration of inverse-kappa goniometers in macromolecular crystallography.

Brockhauser S, White KI, McCarthy AA, Ravelli RB.

Acta Crystallogr A. 2011 May;67(Pt 3):219-28. doi: 10.1107/S0108767311004831. Epub 2011 Mar 15.

25.

Visualizing the metal-binding versatility of copper trafficking sites .

Badarau A, Firbank SJ, McCarthy AA, Banfield MJ, Dennison C.

Biochemistry. 2010 Sep 14;49(36):7798-810. doi: 10.1021/bi101064w.

PMID:
20726513
26.

MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments.

Gabadinho J, Beteva A, Guijarro M, Rey-Bakaikoa V, Spruce D, Bowler MW, Brockhauser S, Flot D, Gordon EJ, Hall DR, Lavault B, McCarthy AA, McCarthy J, Mitchell E, Monaco S, Mueller-Dieckmann C, Nurizzo D, Ravelli RB, Thibault X, Walsh MA, Leonard GA, McSweeney SM.

J Synchrotron Radiat. 2010 Sep;17(5):700-7. doi: 10.1107/S0909049510020005. Epub 2010 Jul 13.

27.

Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain.

Hinz A, Miguet N, Natrajan G, Usami Y, Yamanaka H, Renesto P, Hartlieb B, McCarthy AA, Simorre JP, Göttlinger H, Weissenhorn W.

Cell Host Microbe. 2010 Apr 22;7(4):314-23. doi: 10.1016/j.chom.2010.03.005.

28.

A decade of user operation on the macromolecular crystallography MAD beamline ID14-4 at the ESRF.

McCarthy AA, Brockhauser S, Nurizzo D, Theveneau P, Mairs T, Spruce D, Guijarro M, Lesourd M, Ravelli RB, McSweeney S.

J Synchrotron Radiat. 2009 Nov;16(Pt 6):803-12. doi: 10.1107/S0909049509035377. Epub 2009 Oct 7.

29.

Structure and functional relevance of the Slit2 homodimerization domain.

Seiradake E, von Philipsborn AC, Henry M, Fritz M, Lortat-Jacob H, Jamin M, Hemrika W, Bastmeyer M, Cusack S, McCarthy AA.

EMBO Rep. 2009 Jul;10(7):736-41. doi: 10.1038/embor.2009.95. Epub 2009 Jun 5.

30.

Structure of SRP14 from the Schizosaccharomyces pombe signal recognition particle.

Brooks MA, Ravelli RB, McCarthy AA, Strub K, Cusack S.

Acta Crystallogr D Biol Crystallogr. 2009 May;65(Pt 5):421-33. doi: 10.1107/S0907444909005484. Epub 2009 Apr 18.

PMID:
19390147
31.

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit.

Dias A, Bouvier D, Crépin T, McCarthy AA, Hart DJ, Baudin F, Cusack S, Ruigrok RW.

Nature. 2009 Apr 16;458(7240):914-8. doi: 10.1038/nature07745. Epub 2009 Feb 4.

PMID:
19194459
32.

Structural insights into the Slit-Robo complex.

Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA.

Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14923-8. Epub 2007 Sep 11.

33.

Production of Slit2 LRR domains in mammalian cells for structural studies and the structure of human Slit2 domain 3.

Morlot C, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA.

Acta Crystallogr D Biol Crystallogr. 2007 Sep;63(Pt 9):961-8. Epub 2007 Aug 17.

PMID:
17704564
34.

Cloning, expression, crystallization and preliminary X-ray analysis of the first two Ig domains from human roundabout 1 (Robo1).

Morlot C, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt 8):689-91. Epub 2007 Jul 21.

35.

Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase.

Martinez Molina D, Wetterholm A, Kohl A, McCarthy AA, Niegowski D, Ohlson E, Hammarberg T, Eshaghi S, Haeggström JZ, Nordlund P.

Nature. 2007 Aug 2;448(7153):613-6. Epub 2007 Jul 15.

PMID:
17632546
36.

The structure of two N-methyltransferases from the caffeine biosynthetic pathway.

McCarthy AA, McCarthy JG.

Plant Physiol. 2007 Jun;144(2):879-89. Epub 2007 Apr 13.

37.

Cloning, expression, crystallization and preliminary X-ray analysis of the XMT and DXMT N-methyltransferases from Coffea canephora (robusta).

McCarthy AA, Biget L, Lin C, Petiard V, Tanksley SD, McCarthy JG.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt 4):304-7. Epub 2007 Mar 12.

38.

Structure of dimeric SecA, the Escherichia coli preprotein translocase motor.

Papanikolau Y, Papadovasilaki M, Ravelli RB, McCarthy AA, Cusack S, Economou A, Petratos K.

J Mol Biol. 2007 Mar 9;366(5):1545-57. Epub 2006 Dec 23.

PMID:
17229438
39.

Plastic-embedded protein crystals.

Ravelli RB, Haselmann-Weiss U, McGeehan JE, McCarthy AA, Marquez JA, Antony C, Frangakis AS, Stranzl G.

J Synchrotron Radiat. 2007 Jan;14(Pt 1):128-32. Epub 2006 Dec 15.

PMID:
17211079
40.

Broad institute: bringing genomics to real-world medicine.

McCarthy AA.

Chem Biol. 2005 Jul;12(7):717-8. No abstract available.

41.

Advanced cell technology: embryonic-stem-cell-based regenerative medicine.

McCarthy AA.

Chem Biol. 2005 Jun;12(6):605-7. No abstract available.

42.

Dendritic NanoTechnologies, Inc.

McCarthy AA.

Chem Biol. 2005 May;12(5):499-501. No abstract available.

43.

Exelixis: integrated drug-discovery and development platform for human therapeutics.

McCarthy AA.

Chem Biol. 2005 Apr;12(4):407-8. No abstract available.

44.

Inhibitex, Inc: antibody anti-infectives.

McCarthy AA.

Chem Biol. 2005 Mar;12(3):257-9. No abstract available.

45.

Biolex, Inc.: pharmaceutical production in plants.

McCarthy AA.

Chem Biol. 2005 Feb;12(2):141-2. No abstract available.

46.

New approaches to diabetes disease control, insulin delivery, and monitoring.

McCarthy AA.

Chem Biol. 2004 Dec;11(12):1597-8. No abstract available.

47.

The genetics of autism.

McCarthy AA.

Chem Biol. 2004 Oct;11(10):1325-6. No abstract available.

PMID:
15489156
48.

Structure and function of the C-terminal domain of the polymerase cofactor of rabies virus.

Mavrakis M, McCarthy AA, Roche S, Blondel D, Ruigrok RW.

J Mol Biol. 2004 Oct 29;343(4):819-31.

PMID:
15476803
49.

When enough is too much: new strategies to treat obesity.

McCarthy AA.

Chem Biol. 2004 Aug;11(8):1025-6. No abstract available.

PMID:
15324799
50.

Polymerix corporation: polymer drugs for device and injection.

McCarthy AA.

Chem Biol. 2004 Jul;11(7):885-6. No abstract available.

PMID:
15271342

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