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Too MAD or not MAD enough: The duplicitous role of the spindle assembly checkpoint protein MAD2 in cancer.

Bates M, Furlong F, Gallagher MF, Spillane CD, McCann A, O'Toole S, O'Leary JJ.

Cancer Lett. 2019 Oct 5. pii: S0304-3835(19)30496-3. doi: 10.1016/j.canlet.2019.10.005. [Epub ahead of print]


Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients.

Ulvik A, Midttun Ø, McCann A, Meyer K, Tell G, Nygård O, Ueland PM.

Am J Clin Nutr. 2019 Sep 26. pii: nqz228. doi: 10.1093/ajcn/nqz228. [Epub ahead of print]


From Awareness to Prognosis: Ethical Implications of Uncovering Hidden Awareness in Behaviorally Nonresponsive Patients.

Graham M, Wallace E, Doherty C, McCann A, Naci L.

Camb Q Healthc Ethics. 2019 Oct;28(4):616-631. doi: 10.1017/S0963180119000550.


Exploratory analysis of covariation of microbiota-derived vitamin K and cognition in older adults.

McCann A, Jeffery IB, Ouliass B, Ferland G, Fu X, Booth SL, Tran TT, O'Toole PW, O'Connor EM.

Am J Clin Nutr. 2019 Sep 13. pii: nqz220. doi: 10.1093/ajcn/nqz220. [Epub ahead of print]


Rapid Visualization of Chemically Related Compounds Using Kendrick Mass Defect As a Filter in Mass Spectrometry Imaging.

Kune C, McCann A, Raphaël R, Arias AA, Tiquet M, Van Kruining D, Martinez PM, Ongena M, Eppe G, Quinton L, Far J, De Pauw E.

Anal Chem. 2019 Sep 25. doi: 10.1021/acs.analchem.9b03333. [Epub ahead of print]


TMAO, creatine and 1-methylhistidine in serum and urine are potential biomarkers of cod and salmon intake: a randomised clinical trial in adults with overweight or obesity.

Hagen IV, Helland A, Bratlie M, Midttun Ø, McCann A, Sveier H, Rosenlund G, Mellgren G, Ueland PM, Gudbrandsen OA.

Eur J Nutr. 2019 Aug 10. doi: 10.1007/s00394-019-02076-4. [Epub ahead of print]


Urine and plasma concentrations of amino acids and plasma vitamin status differ, and are differently affected by salmon intake, in obese Zucker fa/fa rats with impaired kidney function and in Long-Evans rats with healthy kidneys.

Drotningsvik A, Midttun Ø, Vikøren LA, McCann A, Ueland PM, Mellgren G, Gudbrandsen OA.

Br J Nutr. 2019 Aug 14;122(3):262-273. doi: 10.1017/S0007114519001284. Epub 2019 Aug 9.


Global phylogeography and ancient evolution of the widespread human gut virus crAssphage.

Edwards RA, Vega AA, Norman HM, Ohaeri M, Levi K, Dinsdale EA, Cinek O, Aziz RK, McNair K, Barr JJ, Bibby K, Brouns SJJ, Cazares A, de Jonge PA, Desnues C, Díaz Muñoz SL, Fineran PC, Kurilshikov A, Lavigne R, Mazankova K, McCarthy DT, Nobrega FL, Reyes Muñoz A, Tapia G, Trefault N, Tyakht AV, Vinuesa P, Wagemans J, Zhernakova A, Aarestrup FM, Ahmadov G, Alassaf A, Anton J, Asangba A, Billings EK, Cantu VA, Carlton JM, Cazares D, Cho GS, Condeff T, Cortés P, Cranfield M, Cuevas DA, De la Iglesia R, Decewicz P, Doane MP, Dominy NJ, Dziewit L, Elwasila BM, Eren AM, Franz C, Fu J, Garcia-Aljaro C, Ghedin E, Gulino KM, Haggerty JM, Head SR, Hendriksen RS, Hill C, Hyöty H, Ilina EN, Irwin MT, Jeffries TC, Jofre J, Junge RE, Kelley ST, Khan Mirzaei M, Kowalewski M, Kumaresan D, Leigh SR, Lipson D, Lisitsyna ES, Llagostera M, Maritz JM, Marr LC, McCann A, Molshanski-Mor S, Monteiro S, Moreira-Grez B, Morris M, Mugisha L, Muniesa M, Neve H, Nguyen NP, Nigro OD, Nilsson AS, O'Connell T, Odeh R, Oliver A, Piuri M, Prussin Ii AJ, Qimron U, Quan ZX, Rainetova P, Ramírez-Rojas A, Raya R, Reasor K, Rice GAO, Rossi A, Santos R, Shimashita J, Stachler EN, Stene LC, Strain R, Stumpf R, Torres PJ, Twaddle A, Ugochi Ibekwe M, Villagra N, Wandro S, White B, Whiteley A, Whiteson KL, Wijmenga C, Zambrano MM, Zschach H, Dutilh BE.

Nat Microbiol. 2019 Oct;4(10):1727-1736. doi: 10.1038/s41564-019-0494-6. Epub 2019 Jul 8.


Detection of pepsin and IL-8 in saliva of adult asthmatic patients.

Marshall S, McCann AJ, Samuels TL, Blair A, Bonne V, Johnston N, Koufman J.

J Asthma Allergy. 2019 May 28;12:155-161. doi: 10.2147/JAA.S205482. eCollection 2019.


Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling.

Ho M, Chen T, Liu J, Dowling P, Hideshima T, Zhang L, Morelli E, Camci-Unal G, Wu X, Tai YT, Wen K, Samur M, Schlossman RL, Mazitschek R, Kavanagh EL, Lindsay S, Harada T, McCann A, Anderson KC, O'Gorman P, Bianchi G.

Leukemia. 2019 May 29. doi: 10.1038/s41375-019-0493-x. [Epub ahead of print]


Correction: BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer.

Shields S, Conroy E, O'Grady T, McGoldrick A, Connor K, Ward MP, Useckaite Z, Dempsey E, Reilly R, Fan Y, Chubb A, Matallanas DG, Kay EW, O'Connor D, McCann A, Gallagher WM, Coppinger JA.

Oncotarget. 2019 May 3;10(33):3144. doi: 10.18632/oncotarget.26920. eCollection 2019 May 3.


Using metabolic profiling and gene expression analyses to explore molecular effects of replacing saturated fat with polyunsaturated fat-a randomized controlled dietary intervention study.

Ulven SM, Christensen JJ, Nygård O, Svardal A, Leder L, Ottestad I, Lysne V, Laupsa-Borge J, Ueland PM, Midttun Ø, Meyer K, McCann A, Andersen LF, Holven KB.

Am J Clin Nutr. 2019 May 1;109(5):1239-1250. doi: 10.1093/ajcn/nqy356.


Plasma Amino Acids and Incident Type 2 Diabetes in Patients With Coronary Artery Disease.

McCann A, Giil LM, Ulvik A, Seifert R, Rebnord EW, Pedersen ER, Svingen GFT, Meyer K, Strand E, Dankel S, Ueland PM, Nygård OK.

Diabetes Care. 2019 Jul;42(7):1225-1233. doi: 10.2337/dc18-2217. Epub 2019 Apr 29.


Effects of low doses of fish and milk proteins on glucose regulation and markers of insulin sensitivity in overweight adults: a randomised, double blind study.

Hovland IH, Leikanger IS, Stokkeland O, Waage KH, Mjøs SA, Brokstad KA, McCann A, Ueland PM, Slizyte R, Carvajal A, Mellgren G, Remman T, Høgøy I, Gudbrandsen OA.

Eur J Nutr. 2019 Apr 10. doi: 10.1007/s00394-019-01963-0. [Epub ahead of print]


Non-invasive imaging techniques for the differentiation of acute and chronic thrombosis.

Yusof NNM, McCann A, Little PJ, Ta HT.

Thromb Res. 2019 May;177:161-171. doi: 10.1016/j.thromres.2019.03.009. Epub 2019 Mar 14. Review.


Hyperglycemia and Metformin Use Are Associated With B Vitamin Deficiency and Cognitive Dysfunction in Older Adults.

Porter KM, Ward M, Hughes CF, O'Kane M, Hoey L, McCann A, Molloy AM, Cunningham C, Casey MC, Tracey F, Strain S, McCarroll K, Laird E, Gallagher AM, McNulty H.

J Clin Endocrinol Metab. 2019 Oct 1;104(10):4837-4847. doi: 10.1210/jc.2018-01791.


Methionine restriction prevents onset of type 2 diabetes in NZO mice.

Castaño-Martinez T, Schumacher F, Schumacher S, Kochlik B, Weber D, Grune T, Biemann R, McCann A, Abraham K, Weikert C, Kleuser B, Schürmann A, Laeger T.

FASEB J. 2019 Jun;33(6):7092-7102. doi: 10.1096/fj.201900150R. Epub 2019 Mar 6.


The role of pepsin in epithelia-mesenchymal transition in idiopathic subglottic stenosis.

McCann AJ, Samuels TL, Blumin JH, Johnston N.

Laryngoscope. 2019 Feb 18. doi: 10.1002/lary.27879. [Epub ahead of print]


Clarifying the mechanisms and resources that enable the reciprocal involvement of seldom heard groups in health and social care research: A collaborative rapid realist review process.

Ní Shé É, Morton S, Lambert V, Ní Cheallaigh C, Lacey V, Dunn E, Loughnane C, O'Connor J, McCann A, Adshead M, Kroll T.

Health Expect. 2019 Jun;22(3):298-306. doi: 10.1111/hex.12865. Epub 2019 Feb 6. Review.


Creating a Supportive Educational Research Culture at a Dental School by Identifying Obstacles and Solutions.

McCann AL, Schneiderman ED.

J Dent Educ. 2019 Mar;83(3):265-274. doi: 10.21815/JDE.019.027. Epub 2019 Jan 28.


The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study.

Solvang SH, Nordrehaug JE, Tell GS, Nygård O, McCann A, Ueland PM, Midttun Ø, Meyer K, Vedeler CA, Aarsland D, Refsum H, Smith AD, Giil LM.

Brain Behav Immun. 2019 Jan;75:155-162. doi: 10.1016/j.bbi.2018.10.003. Epub 2018 Oct 25.


Targeting Proteotoxic Stress in Cancer: A Review of the Role that Protein Quality Control Pathways Play in Oncogenesis.

Guang MHZ, Kavanagh EL, Dunne LP, Dowling P, Zhang L, Lindsay S, Bazou D, Goh CY, Hanley C, Bianchi G, Anderson KC, O'Gorman P, McCann A.

Cancers (Basel). 2019 Jan 9;11(1). pii: E66. doi: 10.3390/cancers11010066. Review.


Novel approach using transoral robotic surgery for resection of cervical spine chordoma.

McCann AC, Berger C, Mahmoud AF, Kuan EC, Malhotra NR, O'Malley BW Jr.

Laryngoscope. 2019 Jun;129(6):1395-1399. doi: 10.1002/lary.27489. Epub 2018 Nov 19.


USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells.

McCann AP, Smyth P, Cogo F, McDaid WJ, Jiang L, Lin J, Evergren E, Burden RE, Van Schaeybroeck S, Scott CJ, Burrows JF.

Cell Commun Signal. 2018 Nov 8;16(1):77. doi: 10.1186/s12964-018-0291-5.


Resident bacteria in breast cancer tissue: pathogenic agents or harmless commensals?

O'Connor H, MacSharry J, Bueso YF, Lindsay S, Kavanagh EL, Tangney M, Clyne M, Saldova R, McCann A.

Discov Med. 2018 Sep;26(142):93-102. Review.


An analysis of the effects of using Zolpidem and an innovative multimodal interdisciplinary team approach in prolonged disorders of consciousness (PDOC).

Delargy M, O'Connor R, McCann A, Galligan I, Cronin H, Gray D, O'Toole C.

Brain Inj. 2019;33(2):242-248. doi: 10.1080/02699052.2018.1537008. Epub 2018 Oct 31.


Atypical Form of Cervicofacial Actinomycosis Involving the Skull Base and Temporal Bone.

McCann A, Alvi SA, Newman J, Kakarala K, Staecker H, Chiu A, Villwock JA.

Ann Otol Rhinol Laryngol. 2019 Feb;128(2):152-156. doi: 10.1177/0003489418808541. Epub 2018 Oct 29. Review.


Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor.

Moustaqil M, Fontaine F, Overman J, McCann A, Bailey TL, Rudolffi Soto P, Bhumkar A, Giles N, Hunter DJB, Gambin Y, Francois M, Sierecki E.

Nucleic Acids Res. 2018 Nov 30;46(21):11381-11395. doi: 10.1093/nar/gky897.


Comparison of Modern Rigid Fixation Plating Outcomes for Segmental Mandibular Microvascular Reconstruction.

McCann AC, Shnayder Y, Przylecki WH, Kakarala K, Nazir N, Girod DA, Andrews BT.

Laryngoscope. 2019 May;129(5):1081-1086. doi: 10.1002/lary.27406. Epub 2018 Oct 3.


Adequate vitamin B12 and riboflavin status from menus alone in residential care facilities in the Lower Mainland, British Columbia.

Whitfield KC, da Silva L, Feldman F, Singh S, McCann A, McAnena L, Ward M, McNulty H, Barr SI, Green TJ.

Appl Physiol Nutr Metab. 2019 Apr;44(4):414-419. doi: 10.1139/apnm-2018-0459. Epub 2018 Sep 24.


Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process.

Calmels C, McCann A, Malphettes L, Andersen MR.

Metab Eng. 2019 Jan;51:9-19. doi: 10.1016/j.ymben.2018.09.009. Epub 2018 Sep 15.


Dietary intake of cod protein beneficially affects concentrations of urinary markers of kidney function and results in lower urinary loss of amino acids in obese Zucker fa/fa rats.

Drotningsvik A, Midttun Ø, McCann A, Ueland PM, Høgøy I, Gudbrandsen OA.

Br J Nutr. 2018 Oct;120(7):740-750. doi: 10.1017/S0007114518002076. Epub 2018 Aug 29.


Immunomodulation in the Treatment of Refractory Catastrophic Antiphospholipid Syndrome.

Nath K, McCann A.

Case Rep Hematol. 2018 Apr 1;2018:1041396. doi: 10.1155/2018/1041396. eCollection 2018.


Viromes of one year old infants reveal the impact of birth mode on microbiome diversity.

McCann A, Ryan FJ, Stockdale SR, Dalmasso M, Blake T, Ryan CA, Stanton C, Mills S, Ross PR, Hill C.

PeerJ. 2018 May 7;6:e4694. doi: 10.7717/peerj.4694. eCollection 2018.


Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles.

Jiang L, Greene MK, Insua JL, Pessoa JS, Small DM, Smyth P, McCann AP, Cogo F, Bengoechea JA, Taggart CC, Scott CJ.

J Control Release. 2018 Jun 10;279:316-325. doi: 10.1016/j.jconrel.2018.04.040. Epub 2018 Apr 25.


BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer.

Shields S, Conroy E, O'Grady T, McGoldrick A, Connor K, Ward MP, Useckaite Z, Dempsey E, Reilly R, Fan Y, Chubb A, Matallanas DG, Kay EW, O'Connor D, McCann A, Gallagher WM, Coppinger JA.

Oncotarget. 2018 Feb 28;9(21):15673-15690. doi: 10.18632/oncotarget.24590. eCollection 2018 Mar 20. Erratum in: Oncotarget. 2019 May 3;10(33):3144.


Reproducible protocols for metagenomic analysis of human faecal phageomes.

Shkoporov AN, Ryan FJ, Draper LA, Forde A, Stockdale SR, Daly KM, McDonnell SA, Nolan JA, Sutton TDS, Dalmasso M, McCann A, Ross RP, Hill C.

Microbiome. 2018 Apr 10;6(1):68. doi: 10.1186/s40168-018-0446-z.


Spontaneous retropharyngeal and mediastinal thoracic duct cyst in an infant with respiratory distress.

Bhalla V, Schrepfer T, McCann A, Nicklaus P, Reading B.

Int J Pediatr Otorhinolaryngol. 2018 Feb;105:33-35. doi: 10.1016/j.ijporl.2017.11.021. Epub 2017 Nov 23.


Effect of Area-Level Socioeconomic Deprivation on Risk of Cognitive Dysfunction in Older Adults.

McCann A, McNulty H, Rigby J, Hughes CF, Hoey L, Molloy AM, Cunningham CJ, Casey MC, Tracey F, O'Kane MJ, McCarroll K, Ward M, Moore K, Strain JJ, Moore A.

J Am Geriatr Soc. 2018 Jul;66(7):1269-1275. doi: 10.1111/jgs.15258. Epub 2018 Feb 12.


The association between MAD2 and prognosis in cancer: a systematic review and meta-analyses.

Byrne T, Coleman HG, Cooper JA, McCluggage WG, McCann A, Furlong F.

Oncotarget. 2017 Jun 8;8(60):102223-102234. doi: 10.18632/oncotarget.18414. eCollection 2017 Nov 24.


A Protocol for Improved Precision and Increased Confidence in Nanoparticle Tracking Analysis Concentration Measurements between 50 and 120 nm in Biological Fluids.

Parsons MEM, McParland D, Szklanna PB, Guang MHZ, O'Connell K, O'Connor HD, McGuigan C, Ní Áinle F, McCann A, Maguire PB.

Front Cardiovasc Med. 2017 Nov 3;4:68. doi: 10.3389/fcvm.2017.00068. eCollection 2017.


Assessing the clinical applicability of prior head imaging in patients with chronic rhinosinusitis.

Bhalla V, McCann A, Sykes K, Hoover L, Beahm DD, Chiu A.

Int Forum Allergy Rhinol. 2018 Jan;8(1):20-24. doi: 10.1002/alr.22042. Epub 2017 Nov 16.


The Impact of Community Rotations on the Cultural Competence of Dental Hygiene Students in the State of Texas.

Classe-Cutrone RA, McCann AL, Campbell PR, DeWald JP, Schneiderman ED.

J Dent Hyg. 2017 Jun;91(3):22-30.


A long and abundant non-coding RNA in Lactobacillus salivarius.

Cousin FJ, Lynch DB, Chuat V, Bourin MJB, Casey PG, Dalmasso M, Harris HMB, McCann A, O'Toole PW.

Microb Genom. 2017 Jul 17;3(9):e000126. doi: 10.1099/mgen.0.000126. eCollection 2017 Sep.


Improving Quality of Chest Radiographs After Placement of Peripherally Inserted Central Catheters.

Jones J, Meek L, Best S, McCann A, Welsh B, Hill J, Ash R.

J Infus Nurs. 2017 Nov/Dec;40(6):359-363. doi: 10.1097/NAN.0000000000000251.


Drug-Eluting Stents Versus Coronary Artery Bypass Grafts for Left Main Coronary Disease: A Meta-Analysis and Review of Randomised Controlled Trials.

Moore P, Burrage M, Garrahy P, Lim R, McCann A, Camuglia A.

Heart Lung Circ. 2018 Dec;27(12):1437-1445. doi: 10.1016/j.hlc.2017.09.008. Epub 2017 Oct 6.


Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells.

Kavanagh EL, Lindsay S, Halasz M, Gubbins LC, Weiner-Gorzel K, Guang MHZ, McGoldrick A, Collins E, Henry M, Blanco-Fernández A, O Gorman P, Fitzpatrick P, Higgins MJ, Dowling P, McCann A.

Oncogenesis. 2017 Oct 9;6(10):e388. doi: 10.1038/oncsis.2017.82.


Amino acid profile and metabolic syndrome in a male Mediterranean population: A cross-sectional study.

Ntzouvani A, Nomikos T, Panagiotakos D, Fragopoulou E, Pitsavos C, McCann A, Ueland PM, Antonopoulou S.

Nutr Metab Cardiovasc Dis. 2017 Nov;27(11):1021-1030. doi: 10.1016/j.numecd.2017.07.006. Epub 2017 Jul 25.


A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer.

O'Sullivan D, Dowling P, Joyce H, McAuley E, McCann A, Henry M, McGovern B, Barham P, Kelleher FC, Murphy J, Kennedy S, Swan N, Moriarty M, Clynes M, Larkin A.

Br J Cancer. 2017 Oct 24;117(9):1326-1335. doi: 10.1038/bjc.2017.306. Epub 2017 Sep 7.


Comparable Performance Characteristics of Plasma Thiamine and Erythrocyte Thiamine Diphosphate in Response to Thiamine Fortification in Rural Cambodian Women.

McCann A, Midttun Ø, Whitfield KC, Kroeun H, Borath M, Sophonneary P, Ueland PM, Green TJ.

Nutrients. 2017 Jun 29;9(7). pii: E676. doi: 10.3390/nu9070676.

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