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Items: 22

1.

A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease.

McArthur JG, Svenstrup N, Chen C, Fricot A, Carvalho C, Nguyen J, Nguyen P, Prachikova A, Abdulla F, Vercellotti GM, Hermine O, Edwards D, Ribeil JA, Belcher JD, Maciel TT.

Haematologica. 2019 May 30. pii: haematol.2018.213462. doi: 10.3324/haematol.2018.213462. [Epub ahead of print]

2.

Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer.

Hege KM, Bergsland EK, Fisher GA, Nemunaitis JJ, Warren RS, McArthur JG, Lin AA, Schlom J, June CH, Sherwin SA.

J Immunother Cancer. 2017 Mar 21;5:22. doi: 10.1186/s40425-017-0222-9. eCollection 2017.

3.

US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.

PMID:
28267733
4.

Production of human clotting Factor IX without toxicity in mice after vascular delivery of a lentiviral vector.

Tsui LV, Kelly M, Zayek N, Rojas V, Ho K, Ge Y, Moskalenko M, Mondesire J, Davis J, Roey MV, Dull T, McArthur JG.

Nat Biotechnol. 2002 Jan;20(1):53-7.

PMID:
11753362
5.

p27-p16 fusion gene inhibits angioplasty-induced neointimal hyperplasia and coronary artery occlusion.

Tsui LV, Camrud A, Mondesire J, Carlson P, Zayek N, Camrud L, Donahue B, Bauer S, Lin A, Frey D, Rivkin M, Subramanian A, Falotico R, Gyuris J, Schwartz R, McArthur JG.

Circ Res. 2001 Aug 17;89(4):323-8.

PMID:
11509448
6.
7.

Anti-Tumor CC49-zeta CD4 T cells possess both cytolytic and helper functions.

Patel SD, Ge Y, Moskalenko M, McArthur JG.

J Immunother. 2000 Nov-Dec;23(6):661-8.

PMID:
11186154
8.

Stability of adenoviral vectors following catheter delivery.

Tsui LV, Zayek N, Frey D, Mello C, Banik G, Falotico R, McArthur JG.

Mol Ther. 2001 Jan;3(1):122-5.

9.

p27-p16 Chimera: a superior antiproliferative for the prevention of neointimal hyperplasia.

McArthur JG, Qian H, Citron D, Banik GG, Lamphere L, Gyuris J, Tsui L, George SE.

Mol Ther. 2001 Jan;3(1):8-13.

10.

T-cell killing of heterogenous tumor or viral targets with bispecific chimeric immune receptors.

Patel SD, Moskalenko M, Tian T, Smith D, McGuinness R, Chen L, Winslow GA, Kashmiri S, Schlom J, Stanners CP, Finer MH, McArthur JG.

Cancer Gene Ther. 2000 Aug;7(8):1127-34.

11.

The p53-independent tumoricidal activity of an adenoviral vector encoding a p27-p16 fusion tumor suppressor gene.

Patel SD, Tran AC, Ge Y, Moskalenko M, Tsui L, Banik G, Tom W, Scott M, Chen L, Van Roey M, Rivkin M, Mendez M, Gyuris J, McArthur JG.

Mol Ther. 2000 Aug;2(2):161-9.

12.

Selective uptake and sustained expression of AAV vectors following subcutaneous delivery.

Donahue BA, McArthur JG, Spratt SK, Bohl D, Lagarde C, Sanchez L, Kaspar BA, Sloan BA, Lee YL, Danos O, Snyder RO.

J Gene Med. 1999 Jan-Feb;1(1):31-42.

PMID:
10738583
13.

Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure.

Moskalenko M, Chen L, van Roey M, Donahue BA, Snyder RO, McArthur JG, Patel SD.

J Virol. 2000 Feb;74(4):1761-6.

14.

Impact of chimeric immune receptor extracellular protein domains on T cell function.

Patel SD, Moskalenko M, Smith D, Maske B, Finer MH, McArthur JG.

Gene Ther. 1999 Mar;6(3):412-9.

15.

Anti-tumor activity of human T cells expressing the CC49-zeta chimeric immune receptor.

McGuinness RP, Ge Y, Patel SD, Kashmiri SV, Lee HS, Hand PH, Schlom J, Finer MH, McArthur JG.

Hum Gene Ther. 1999 Jan 20;10(2):165-73.

PMID:
10022542
16.

Induction of protective anti-tumor immunity by gene-modified dendritic cells.

McArthur JG, Mulligan RC.

J Immunother. 1998 Jan;21(1):41-7.

PMID:
9456435
17.
18.
19.

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones.

Harding FA, McArthur JG, Gross JA, Raulet DH, Allison JP.

Nature. 1992 Apr 16;356(6370):607-9.

PMID:
1313950
20.

Sequence requirements for the stimulation of gene amplification by a mammalian genomic element.

Beitel LK, McArthur JG, Stanners CP.

Gene. 1991 Jun 30;102(2):149-56.

PMID:
1874442
21.
22.

A genetic element that increases the frequency of gene amplification.

McArthur JG, Stanners CP.

J Biol Chem. 1991 Mar 25;266(9):6000-5.

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