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Items: 1 to 50 of 90

1.

In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline.

Pokorna Z, Jirkovsky E, Hlavackova M, Jansova H, Jirkovska A, Lencova-Popelova O, Brazdova P, Kubes J, Sotakova-Kasparova D, Mazurova Y, Adamcova M, Vostatkova L, Holzerova K, Kolar F, Simunek T, Sterba M.

Clin Sci (Lond). 2019 Aug 27;133(16):1827-1844. doi: 10.1042/CS20190139. Print 2019 Aug 30.

PMID:
31409729
2.

[Assessing retinal photosensitivity in patients with central vision impairment using a portable perimeter (a preliminary report)].

Ermolaev AP, Erichev VP, Antonov AA, Grigoryan GL, Kotliar K, Levitsky YV, Hderi K, Mazurova YV.

Vestn Oftalmol. 2019;135(3):46-54. doi: 10.17116/oftalma201913503146. Russian.

PMID:
31393447
3.

Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings?

Lenčová-Popelová O, Jansová H, Jirkovský E, Bureš J, Jirkovská-Vávrová A, Mazurová Y, Reimerová P, Vostatková L, Adamcová M, Hroch M, Pokorná Z, Kovaříková P, Šimůnek T, Štěrba M.

Toxicology. 2016 Nov 30;372:52-63. doi: 10.1016/j.tox.2016.11.002. Epub 2016 Nov 2.

PMID:
27816693
4.

[Centrally acting cholinomimetics in the complex therapy of progressive glaucomatous optic neuropathy].

Erichev VP, Mazurova YV.

Vestn Oftalmol. 2016 Mar-Apr;132(2):33-37. doi: 10.17116/oftalma2016132233-37. Russian.

PMID:
27213795
5.

Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane.

Lenčová-Popelová O, Jirkovský E, Jansová H, Jirkovská-Vávrová A, Vostatková-Tichotová L, Mazurová Y, Adamcová M, Chládek J, Hroch M, Pokorná Z, Geršl V, Šimůnek T, Štěrba M.

J Mol Cell Cardiol. 2016 Feb;91:92-103. doi: 10.1016/j.yjmcc.2015.12.021. Epub 2015 Dec 23.

PMID:
26724189
6.

Experimental determination of diagnostic window of cardiac troponins in the development of chronic anthracycline cardiotoxicity and estimation of its predictive value.

Adamcova M, Lencova-Popelova O, Jirkovsky E, Mazurova Y, Palicka V, Simko F, Gersl V, Sterba M.

Int J Cardiol. 2015 Dec 15;201:358-67. doi: 10.1016/j.ijcard.2015.07.103. Epub 2015 Aug 4.

PMID:
26310978
7.

Transgenic rat model of Huntington's disease: a histopathological study and correlations with neurodegenerative process in the brain of HD patients.

Mazurová Y, Anderova M, Němečková I, Bezrouk A.

Biomed Res Int. 2014;2014:291531. doi: 10.1155/2014/291531. Epub 2014 Aug 3.

8.

Molecular remodeling of left and right ventricular myocardium in chronic anthracycline cardiotoxicity and post-treatment follow up.

Lenčová-Popelová O, Jirkovský E, Mazurová Y, Lenčo J, Adamcová M, Šimůnek T, Geršl V, Štěrba M.

PLoS One. 2014 May 7;9(5):e96055. doi: 10.1371/journal.pone.0096055. eCollection 2014.

9.

Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits.

Jirkovský E, Lenčová-Popelová O, Hroch M, Adamcová M, Mazurová Y, Vávrová J, Mičuda S, Šimůnek T, Geršl V, Štěrba M.

Toxicology. 2013 Sep 15;311(3):191-204. doi: 10.1016/j.tox.2013.06.012. Epub 2013 Jul 4.

PMID:
23831762
10.

The anticancer activity of alpha-tomatine against mammary adenocarcinoma in mice.

Tomsik P, Micuda S, Sucha L, Cermakova E, Suba P, Zivny P, Mazurova Y, Knizek J, Niang M, Rezacova M.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2013 Jun;157(2):153-61. doi: 10.5507/bp.2013.031. Epub 2013 May 3.

11.

Specific features of mandible structure and elemental composition in the polyphagous amphipod Acanthogammarus grewingkii endemic to Lake Baikal.

Mekhanikova IV, Andreev DS, Belozerova OY, Mikhlin YL, Lipko SV, Klimenkov IV, Akimov VV, Kargin VF, Mazurova YV, Tauson VL, Likhoshway YV.

PLoS One. 2012;7(8):e43073. doi: 10.1371/journal.pone.0043073. Epub 2012 Aug 10.

12.

Intervention of Proliferation and Differentiation of Endogenous Neural Stem Cells in the Neurodegenerative Process of Huntington's Disease Phenotype.

Mazurová Y, Gunčová I, Látr I, Rudolf E.

CNS Neurol Disord Drug Targets. 2011 Jun;10(4):486-99. Review.

PMID:
21495959
13.

Proteomic insights into chronic anthracycline cardiotoxicity.

Stěrba M, Popelová O, Lenčo J, Fučíková A, Brčáková E, Mazurová Y, Jirkovský E, Simůnek T, Adamcová M, Mičuda S, Stulík J, Geršl V.

J Mol Cell Cardiol. 2011 May;50(5):849-62. doi: 10.1016/j.yjmcc.2011.01.018. Epub 2011 Jan 31.

PMID:
21284945
14.

The neurodegenerative process in a neurotoxic rat model and in patients with Huntington's disease: histopathological parallels and differences.

Gunčová I, Látr I, Mazurová Y.

Acta Histochem. 2011 Dec;113(8):783-92. doi: 10.1016/j.acthis.2010.11.007. Epub 2010 Dec 28.

PMID:
21193226
15.

The effect of rat strain, diet composition and feeding period on the development of a nutritional model of non-alcoholic fatty liver disease in rats.

Kučera O, Garnol T, Lotková H, Staňková P, Mazurová Y, Hroch M, Bolehovská R, Roušar T, Červinková Z.

Physiol Res. 2011;60(2):317-28. Epub 2010 Nov 29.

16.

Cardiac remodeling and MMPs on the model of chronic daunorubicin-induced cardiomyopathy in rabbits.

Adamcová M, Potáčová A, Popelová O, Stěrba M, Mazurová Y, Aupperle H, Geršl V.

Physiol Res. 2010;59(5):831-6. Epub 2010 Apr 20.

17.

Cardiac biomarkers in a model of acute catecholamine cardiotoxicity.

Mladenka P, Hrdina R, Bobrovová Z, Semecky V, Vávrová J, Holecková M, Palicka V, Mazurová Y, Nachtigal P.

Hum Exp Toxicol. 2009 Oct;28(10):631-40. doi: 10.1177/0960327109350665. Epub 2009 Oct 7.

PMID:
19812120
18.

Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death.

Popelová O, Sterba M, Hasková P, Simůnek T, Hroch M, Guncová I, Nachtigal P, Adamcová M, Gersl V, Mazurová Y.

Br J Cancer. 2009 Sep 1;101(5):792-802. doi: 10.1038/sj.bjc.6605192. Epub 2009 Jul 21.

19.

The novel iron chelator, 2-pyridylcarboxaldehyde 2-thiophenecarboxyl hydrazone, reduces catecholamine-mediated myocardial toxicity.

Mladĕnka P, Kalinowski DS, Haskova P, Bobrovová Z, Hrdina R, Simůnek T, Nachtigal P, Semecký V, Vávrová J, Holeckova M, Palicka V, Mazurová Y, Jansson PJ, Richardson DR.

Chem Res Toxicol. 2009 Jan;22(1):208-17.

PMID:
19172757
20.

The effects of lactoferrin in a rat model of catecholamine cardiotoxicity.

Mladenka P, Semecký V, Bobrovová Z, Nachtigal P, Vávrová J, Holecková M, Palicka V, Mazurová Y, Hrdina R.

Biometals. 2009 Apr;22(2):353-61. doi: 10.1007/s10534-008-9172-5. Epub 2008 Nov 4.

PMID:
18982411
21.

Deferiprone does not protect against chronic anthracycline cardiotoxicity in vivo.

Popelová O, Sterba M, Simůnek T, Mazurová Y, Guncová I, Hroch M, Adamcová M, Gersl V.

J Pharmacol Exp Ther. 2008 Jul;326(1):259-69. doi: 10.1124/jpet.108.137604. Epub 2008 Apr 23.

PMID:
18434588
22.

Pyridoxal isonicotinoyl hydrazone (PIH) and its analogs as protectants against anthracycline-induced cardiotoxicity.

Simunek T, Sterba M, Popelova O, Kaiserova H, Potacova A, Adamcova M, Mazurova Y, Ponka P, Gersl V.

Hemoglobin. 2008;32(1-2):207-15. doi: 10.1080/03630260701680276.

PMID:
18274998
23.

A pilot study of matrix metalloproteinases on the model of daunorubicin-induced cardiomyopathy in rabbits.

Potácová A, Adamcová M, Sterba M, Popelová O, Simůnek T, Mazurová Y, Guncová I, Gersl V.

Acta Medica (Hradec Kralove). 2007;50(2):109-11.

24.

Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: a study of salicylaldehyde isonicotinoyl hydrazone (SIH).

Sterba M, Popelová O, Simůnek T, Mazurová Y, Potácová A, Adamcová M, Guncová I, Kaiserová H, Palicka V, Ponka P, Gersl V.

Toxicology. 2007 Jun 25;235(3):150-66. Epub 2007 Mar 24.

PMID:
17459556
25.

Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination.

Sterba M, Simůnek T, Popelová O, Potácová A, Adamcová M, Mazurová Y, Holecková M, Gersl V.

Physiol Res. 2007;56(5):535-45. Epub 2006 Dec 19.

26.

Cardioprotective effects of a novel iron chelator, pyridoxal 2-chlorobenzoyl hydrazone, in the rabbit model of daunorubicin-induced cardiotoxicity.

Sterba M, Popelová O, Simunek T, Mazurová Y, Potácová A, Adamcová M, Kaiserová H, Ponka P, Gersl V.

J Pharmacol Exp Ther. 2006 Dec;319(3):1336-47. Epub 2006 Sep 26.

PMID:
17003229
27.

Proliferation and differentiation of adult endogenous neural stem cells in response to neurodegenerative process within the striatum.

Mazurová Y, Rudolf E, Látr I, Osterreicher J.

Neurodegener Dis. 2006;3(1-2):12-8. Review.

PMID:
16909031
28.

Progressive reparative gliosis in aged hosts and interferences with neural grafts in an animal model of Huntington's disease.

Mazurová Y, Látr I, Osterreicher J, Guncová I.

Cell Mol Neurobiol. 2006 Oct-Nov;26(7-8):1423-41. Epub 2006 Jun 14.

PMID:
16773446
29.

Safety and tolerability of repeated administration of pyridoxal 2-chlorobenzoyl hydrazone in rabbits.

Sterba M, Simůnek T, Mazurová Y, Adamcová M, Popelová O, Kaplanova J, Ponka P, Gersl V.

Hum Exp Toxicol. 2005 Nov;24(11):581-9.

PMID:
16323575
30.
31.

Troponin as a marker of myocardiac damage in drug-induced cardiotoxicity.

Adamcova M, Sterba M, Simunek T, Potacova A, Popelova O, Mazurova Y, Gersl V.

Expert Opin Drug Saf. 2005 May;4(3):457-72. Review.

PMID:
15934853
32.

Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbits.

Simůnek T, Klimtová I, Kaplanová J, Sterba M, Mazurová Y, Adamcová M, Hrdina R, Gersl V, Ponka P.

Pharmacol Res. 2005 Mar;51(3):223-31.

PMID:
15661572
33.

Role of type II pneumocytes in pathogenesis of radiation pneumonitis: dose response of radiation-induced lung changes in the transient high vascular permeability period.

Osterreicher J, Pejchal J, Skopek J, Mokrỳ J, Vilasová Z, Psutka J, Vávrová J, Mazurová Y.

Exp Toxicol Pathol. 2004 Dec;56(3):181-7.

PMID:
15625787
34.

Rabbit model for in vivo study of anthracycline-induced heart failure and for the evaluation of protective agents.

Simůnek T, Klimtová I, Kaplanová J, Mazurová Y, Adamcová M, Sterba M, Hrdina R, Gersl V.

Eur J Heart Fail. 2004 Jun;6(4):377-87.

35.

Protein profiling in daunorubicin-induced cardiomyopathy.

Adamcová M, Pelouch V, Gersl V, Kaplanová J, Mazurová Y, Simůnek T, Klimtová I, Hrdina R.

Gen Physiol Biophys. 2003 Sep;22(3):411-9.

36.

A study of potential toxic effects after repeated 10-week administration of a new iron chelator--salicylaldehyde isonicotinoyl hydrazone (SIH) to rabbits.

Klimtová I, Simůnek T, Mazurová Y, Kaplanová J, Sterba M, Hrdina R, Gersl V, Adamcová M, Ponka P.

Acta Medica (Hradec Kralove). 2003;46(4):163-70.

PMID:
14965167
37.

Cardiac troponin T as an indicator of reduced left ventricular contractility in experimental anthracycline-induced cardiomyopathy.

Simůnek T, Klimtová I, Adamcová M, Gersl V, Hrdina R, Sterba M, Kaplanová J, Mazurová Y.

Cancer Chemother Pharmacol. 2003 Nov;52(5):431-4. Epub 2003 Jul 9.

PMID:
14618274
38.

The reaction of the subependymal layer of lateral brain ventricles to striatal ibotenic acid lesions in a long-term study.

Mazurová Y, Valousková V, Osterreicher J.

Acta Histochem. 2002;104(4):375-9.

PMID:
12553706
39.

Comparative study of chronic toxic effects of daunorubicin and doxorubicin in rabbits.

Klimtová I, Simůnek T, Mazurová Y, Hrdina R, Gersl V, Adamcová M.

Hum Exp Toxicol. 2002 Dec;21(12):649-57.

PMID:
12540035
40.

Effect of sodium 2,3-dimercaptopropane-1-sulphonate (DMPS) on chronic daunorubicin toxicity in rabbits: comparison with dexrazoxane.

Hrdina R, Gersl V, Klimtová I, Simůnek T, Mazurová Y, Machácková J, Adamcová M.

Acta Medica (Hradec Kralove). 2002;45(3):99-105.

PMID:
12515046
41.

[Plasma levels of troponin T in rabbits after administration of new antineoplastic agents (Oracin and Dimefluron) and daunorubicin].

Adamcová M, Machácková J, Gersl V, Hrdina R, Mazurová Y, Mĕlka M, Nobilis M.

Acta Medica (Hradec Kralove) Suppl. 2001;44(1):3-8. Czech.

PMID:
11892362
42.

New therapeutic approaches for the treatment of Huntington's disease.

Mazurová Y.

Acta Medica (Hradec Kralove). 2001;44(4):119-23. Review.

PMID:
11836846
43.

[An animal model of Huntington's disease: the development of histopathological changes within the neurotoxic lesions of the striatum in long-term surviving rats].

Mazurová Y, Osterreicher J, Valousková V.

Acta Medica (Hradec Kralove) Suppl. 2002;45(2):53-64. Czech.

PMID:
19569580
44.

Evaluation of cardiac effects of the new antineoplastic drug --dimethoxybenfluron--in the rabbit.

Machacková J, Adamcová M, Mazurová Y, Hrdina R, Nobilis M.

Physiol Res. 2001;50(5):491-9.

45.

[Effects of new antineoplastic agents (dimethoxybenflurone and Oracin) on the cardiovascular system and other parameters in the rabbit in vivo].

Machácková J, Gersl V, Adamcová M, Mazurová Y, Hrdina R, Mĕlka M, Nobilis M.

Acta Medica (Hradec Kralove) Suppl. 2000;43(2):119-38. Czech.

PMID:
11413675
46.

Cholinesterases in dexrazoxane-treated daunorubicin cardiomyopathy in rabbits.

Gersl V, Bajgar J, Hrdina R, Mazurová Y, Machácková J, Cerman J, Suba P.

Gen Physiol Biophys. 1999 Dec;18(4):335-46.

PMID:
10766032
47.

Cardiac troponin T as a marker of myocardial damage caused by antineoplastic drugs in rabbits.

Adamcová M, Gersl V, Hrdina R, Melka M, Mazurová Y, Vávrová J, Palicka V, Kokstein Z.

J Cancer Res Clin Oncol. 1999;125(5):268-74.

PMID:
10359131
48.

IGF-I in experimental daunorubicin-induced cardiomyopathy in rabbits.

Gersl V, Cerman J, Suba P, Mazurová Y, Hrdina R, Machácková J.

Hum Exp Toxicol. 1999 Mar;18(3):154-61.

PMID:
10215105
49.

Myocardial elements content and cardiac function after repeated i.v. administration of DMPS in rabbits.

Hrdina R, Gersl V, Vávrová J, Holecková M, Palicka V, Voglová J, Mazurová Y, Bajgar J.

Hum Exp Toxicol. 1998 Apr;17(4):221-4.

PMID:
9617634
50.

The effects of subchronical exposure to SO2 on biochemical and hematological parameters in guinea pigs.

Suchánková J, Gersl V, Fiala Z, Mazurová Y, Palicka V, Vávrová J, Voglová J, Visnovský P.

Acta Medica (Hradec Kralove). 1997;40(4):95-7.

PMID:
9481882

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