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Items: 36


PDK1 Mediates NOTCH1-Mutated Head and Neck Squamous Carcinoma Vulnerability to Therapeutic PI3K/mTOR Inhibition.

Sambandam V, Frederick MJ, Shen L, Tong P, Rao X, Peng S, Singh R, Mazumdar T, Huang C, Li Q, Pickering CR, Myers JN, Wang J, Johnson FM.

Clin Cancer Res. 2019 Jun 1;25(11):3329-3340. doi: 10.1158/1078-0432.CCR-18-3276. Epub 2019 Feb 15.


Comprehensive pharmacogenomic profiling of human papillomavirus-positive and -negative squamous cell carcinoma identifies sensitivity to aurora kinase inhibition in KMT2D mutants.

Kalu NN, Mazumdar T, Peng S, Tong P, Shen L, Wang J, Banerjee U, Myers JN, Pickering CR, Brunell D, Stephan CC, Johnson FM.

Cancer Lett. 2018 Sep 1;431:64-72. doi: 10.1016/j.canlet.2018.05.029. Epub 2018 May 25.


Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.

Kalu NN, Mazumdar T, Peng S, Shen L, Sambandam V, Rao X, Xi Y, Li L, Qi Y, Gleber-Netto FO, Patel A, Wang J, Frederick MJ, Myers JN, Pickering CR, Johnson FM.

Oncotarget. 2017 Sep 21;8(49):86369-86383. doi: 10.18632/oncotarget.21174. eCollection 2017 Oct 17.


Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors.

Zhang M, Singh R, Peng S, Mazumdar T, Sambandam V, Shen L, Tong P, Li L, Kalu NN, Pickering CR, Frederick M, Myers JN, Wang J, Johnson FM.

Cancer Lett. 2017 Apr 28;392:71-82. doi: 10.1016/j.canlet.2017.01.024. Epub 2017 Jan 23.


Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations.

Peng S, Sen B, Mazumdar T, Byers LA, Diao L, Wang J, Tong P, Giri U, Heymach JV, Kadara HN, Johnson FM.

Oncotarget. 2016 Jan 5;7(1):565-79. doi: 10.18632/oncotarget.6376.


Drug-induced RAF dimerization is independent of RAS mutation status and does not lead to universal MEK dependence for cell survival in head and neck cancers.

Mazumdar T, Sen B, Wang Y, Peng S, Nicholas C, Glisson BS, Myers JN, Johnson FM.

Anticancer Drugs. 2015 Sep;26(8):835-42. doi: 10.1097/CAD.0000000000000251.


A comprehensive evaluation of biomarkers predictive of response to PI3K inhibitors and of resistance mechanisms in head and neck squamous cell carcinoma.

Mazumdar T, Byers LA, Ng PK, Mills GB, Peng S, Diao L, Fan YH, Stemke-Hale K, Heymach JV, Myers JN, Glisson BS, Johnson FM.

Mol Cancer Ther. 2014 Nov;13(11):2738-50. doi: 10.1158/1535-7163.MCT-13-1090. Epub 2014 Sep 5.


Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.

Agyeman A, Jha BK, Mazumdar T, Houghton JA.

Oncotarget. 2014 Jun 30;5(12):4492-503.


Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells.

Mazumdar T, Sandhu R, Qadan M, DeVecchio J, Magloire V, Agyeman A, Li B, Houghton JA.

PLoS One. 2013 Sep 25;8(9):e75253. doi: 10.1371/journal.pone.0075253. eCollection 2013.


Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers.

Peng S, Creighton CJ, Zhang Y, Sen B, Mazumdar T, Myers JN, Lai SY, Woolfson A, Lorenzi MV, Bell D, Williams MD, Johnson FM.

J Transl Med. 2013 Aug 27;11:198. doi: 10.1186/1479-5876-11-198. Erratum in: J Transl Med. 2014;12:67. Lai, Stephen Y [added].


Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib.

Sen B, Peng S, Tang X, Erickson HS, Galindo H, Mazumdar T, Stewart DJ, Wistuba I, Johnson FM.

Sci Transl Med. 2012 May 30;4(136):136ra70. doi: 10.1126/scitranslmed.3003513.


Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling.

Lei JT, Mazumdar T, Martinez-Moczygemba M.

J Biol Chem. 2011 Nov 18;286(46):40091-103. doi: 10.1074/jbc.M111.273482. Epub 2011 Sep 30.


The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.

Mazumdar T, DeVecchio J, Agyeman A, Shi T, Houghton JA.

Oncotarget. 2011 Aug;2(8):638-45.


Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.

Mazumdar T, Devecchio J, Agyeman A, Shi T, Houghton JA.

Cancer Res. 2011 Sep 1;71(17):5904-14. doi: 10.1158/0008-5472.CAN-10-4173. Epub 2011 Jul 11.


p300- and Myc-mediated regulation of glioblastoma multiforme cell differentiation.

Panicker SP, Raychaudhuri B, Sharma P, Tipps R, Mazumdar T, Mal AK, Palomo JM, Vogelbaum MA, Haque SJ.

Oncotarget. 2010 Aug;1(4):289-303.


Hedgehog signaling drives cellular survival in human colon carcinoma cells.

Mazumdar T, DeVecchio J, Shi T, Jones J, Agyeman A, Houghton JA.

Cancer Res. 2011 Feb 1;71(3):1092-102. doi: 10.1158/0008-5472.CAN-10-2315. Epub 2010 Dec 6.


cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.

Shi T, Mazumdar T, Devecchio J, Duan ZH, Agyeman A, Aziz M, Houghton JA.

PLoS One. 2010 Oct 1;5(10). pii: e13054. doi: 10.1371/journal.pone.0013054.


Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13).

Mazumdar T, Gorgun FM, Sha Y, Tyryshkin A, Zeng S, Hartmann-Petersen R, Jørgensen JP, Hendil KB, Eissa NT.

Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13854-9. doi: 10.1073/pnas.0913495107. Epub 2010 Jul 15.


Src kinase-mediated phosphorylation stabilizes inducible nitric-oxide synthase in normal cells and cancer cells.

Tyryshkin A, Gorgun FM, Abdel Fattah E, Mazumdar T, Pandit L, Zeng S, Eissa NT.

J Biol Chem. 2010 Jan 1;285(1):784-92. doi: 10.1074/jbc.M109.055038. Epub 2009 Oct 29.


Identification of a flavin mononucleotide module residue critical for activity of inducible nitrite oxide synthase.

Liu XD, Mazumdar T, Xu Y, Getzoff ED, Eissa NT.

J Immunol. 2009 Nov 1;183(9):5977-82. doi: 10.4049/jimmunol.0902274. Epub 2009 Oct 14.


Comparison of liposome based antigen delivery systems for protection against Leishmania donovani.

Bhowmick S, Mazumdar T, Sinha R, Ali N.

J Control Release. 2010 Jan 25;141(2):199-207. doi: 10.1016/j.jconrel.2009.09.018. Epub 2009 Oct 7.


Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection.

Bhowmick S, Mazumdar T, Ali N.

Infect Immun. 2009 Apr;77(4):1514-23. doi: 10.1128/IAI.01739-07. Epub 2009 Jan 21.


16-kDa prolactin down-regulates inducible nitric oxide synthase expression through inhibition of the signal transducer and activator of transcription 1/IFN regulatory factor-1 pathway.

Lee SH, Nishino M, Mazumdar T, Garcia GE, Galfione M, Lee FL, Lee CL, Liang A, Kim J, Feng L, Eissa NT, Lin SH, Yu-Lee LY.

Cancer Res. 2005 Sep 1;65(17):7984-92.


Leishmania promastigote membrane antigen-based enzyme-linked immunosorbent assay and immunoblotting for differential diagnosis of Indian post-kala-azar dermal leishmaniasis.

Saha S, Mazumdar T, Anam K, Ravindran R, Bairagi B, Saha B, Goswami R, Pramanik N, Guha SK, Kar S, Banerjee D, Ali N.

J Clin Microbiol. 2005 Mar;43(3):1269-77.


Management of chronic hepatitis B infection: an update.

Mazumdar TN.

J Indian Med Assoc. 2001 Jun;99(6):306-8, 310. Review.


Hepatic artery aneurysm.

Mazumdar DK, Sarkar CN, Sarkar TJ, Mazumdar TN.

J Assoc Physicians India. 1999 Nov;47(11):1127. No abstract available.


Formulation of a scoring chart for irritable bowel syndrome (IBS): a prospective study.

Mazumdar TN, Prasad KV, Bhat PV.

Indian J Gastroenterol. 1988 Apr;7(2):101-2. No abstract available.


Cholestatic jaundice--a retrospective study.

Mazumdar TN, Bhargava DK, Tandon BN, Tandon HD, Berry M.

J Assoc Physicians India. 1980 Oct;28(10):343-7. No abstract available.


A study of sporadic veno-occlusive disease of liver.

Mazumdar TN, Chandra U, Tandon HD.

J Assoc Physicians India. 1979 Jul;27(7):631-5. No abstract available.


Improved prognosis of fulminant hepatitis by a simple supportive therapeutic regimen.

Tandon BN, Sharma MP, Tandon RK, Koshy A, Narendranathan M, Mazumdar TN.

Indian J Med Res. 1978 Mar;67:401-5. No abstract available.


Hookworm duodenitis--an endoscopic and gastric secretory study.

Mazumdar TN, Tandon RK, Bajaj JS.

J Assoc Physicians India. 1978 Jan;26(1):35-40. No abstract available.


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