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Items: 16

1.

Mutagenesis of the Microcystin Tailoring and Transport Proteins in a Heterologous Cyanotoxin Expression System.

Liu T, Mazmouz R, Pearson LA, Neilan BA.

ACS Synth Biol. 2019 May 17;8(5):1187-1194. doi: 10.1021/acssynbio.9b00068. Epub 2019 May 7.

PMID:
31042359
2.

Heterologous expression and biochemical characterisation of cyanotoxin biosynthesis pathways.

Cullen A, Pearson LA, Mazmouz R, Liu T, Soeriyadi AH, Ongley SE, Neilan BA.

Nat Prod Rep. 2019 Aug 14;36(8):1117-1136. doi: 10.1039/c8np00063h. Review.

PMID:
30556569
3.

Insertions within the Saxitoxin Biosynthetic Gene Cluster Result in Differential Toxin Profiles.

Cullen A, D'Agostino PM, Mazmouz R, Pickford R, Wood S, Neilan BA.

ACS Chem Biol. 2018 Nov 16;13(11):3107-3114. doi: 10.1021/acschembio.8b00608. Epub 2018 Oct 19.

PMID:
30296060
4.

Characterization of CyrI, the hydroxylase involved in the last step of cylindrospermopsin biosynthesis: Binding studies, site-directed mutagenesis and stereoselectivity.

Mazmouz R, Essadik I, Hamdane D, Méjean A, Ploux O.

Arch Biochem Biophys. 2018 Jun 1;647:1-9. doi: 10.1016/j.abb.2018.04.007. Epub 2018 Apr 11.

PMID:
29653078
5.

An In Vitro and In Vivo Study of Broad-Range Phosphopantetheinyl Transferases for Heterologous Expression of Cyanobacterial Natural Products.

Liu T, Mazmouz R, Neilan BA.

ACS Synth Biol. 2018 Apr 20;7(4):1143-1151. doi: 10.1021/acssynbio.8b00091. Epub 2018 Mar 27.

PMID:
29562128
6.

Molecular and morphological survey of saxitoxin-producing cyanobacterium Dolichospermum circinale (Anabaena circinalis) isolated from geographically distinct regions of Australia.

Pereyra JPA, D'Agostino PM, Mazmouz R, Woodhouse JN, Pickford R, Jameson I, Neilan BA.

Toxicon. 2017 Nov;138:68-77. doi: 10.1016/j.toxicon.2017.08.006. Epub 2017 Aug 7.

PMID:
28797629
7.

Directing the Heterologous Production of Specific Cyanobacterial Toxin Variants.

Liu T, Mazmouz R, Ongley SE, Chau R, Pickford R, Woodhouse JN, Neilan BA.

ACS Chem Biol. 2017 Aug 18;12(8):2021-2029. doi: 10.1021/acschembio.7b00181. Epub 2017 Jun 7.

PMID:
28570054
8.

The genetics, biosynthesis and regulation of toxic specialized metabolites of cyanobacteria.

Pearson LA, Dittmann E, Mazmouz R, Ongley SE, D'Agostino PM, Neilan BA.

Harmful Algae. 2016 Apr;54:98-111. doi: 10.1016/j.hal.2015.11.002. Review.

PMID:
28073484
9.

Heterologous Production of Cyanobacterial Mycosporine-Like Amino Acids Mycosporine-Ornithine and Mycosporine-Lysine in Escherichia coli.

Katoch M, Mazmouz R, Chau R, Pearson LA, Pickford R, Neilan BA.

Appl Environ Microbiol. 2016 Sep 30;82(20):6167-6173. Print 2016 Oct 15.

10.

Comparative Profiling and Discovery of Novel Glycosylated Mycosporine-Like Amino Acids in Two Strains of the Cyanobacterium Scytonema cf. crispum.

D'Agostino PM, Javalkote VS, Mazmouz R, Pickford R, Puranik PR, Neilan BA.

Appl Environ Microbiol. 2016 Sep 16;82(19):5951-9. doi: 10.1128/AEM.01633-16. Print 2016 Oct 1.

11.
12.

PpiA, a surface PPIase of the cyclophilin family in Lactococcus lactis.

Trémillon N, Morello E, Llull D, Mazmouz R, Gratadoux JJ, Guillot A, Chapot-Chartier MP, Monlezun L, Solé V, Ginisty H, Poquet I.

PLoS One. 2012;7(3):e33516. doi: 10.1371/journal.pone.0033516. Epub 2012 Mar 19.

13.

The last step of the biosynthesis of the cyanotoxins cylindrospermopsin and 7-epi-cylindrospermopsin is catalysed by CyrI, a 2-Oxoglutarate-dependent iron oxygenase.

Mazmouz R, Chapuis-Hugon F, Pichon V, Méjean A, Ploux O.

Chembiochem. 2011 Apr 11;12(6):858-62. doi: 10.1002/cbic.201000726. Epub 2011 Mar 14. No abstract available.

PMID:
21404419
14.

Adaptive differentiation of Plasmodium falciparum populations inferred from single-nucleotide polymorphisms (SNPs) conferring drug resistance and from neutral SNPs.

Maïga-Ascofaré O, Le Bras J, Mazmouz R, Renard E, Falcão S, Broussier E, Bustos D, Randrianarivelojosia M, Omar SA, Aubouy A, Lepère JF, Jean-François V, Djimdé AA, Clain J.

J Infect Dis. 2010 Oct 1;202(7):1095-103. doi: 10.1086/656142.

PMID:
20726766
15.

The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506 reveals several gene clusters responsible for the biosynthesis of toxins and secondary metabolites.

Méjean A, Mazmouz R, Mann S, Calteau A, Médigue C, Ploux O.

J Bacteriol. 2010 Oct;192(19):5264-5. doi: 10.1128/JB.00704-10. Epub 2010 Jul 30.

16.

Biosynthesis of cylindrospermopsin and 7-epicylindrospermopsin in Oscillatoria sp. strain PCC 6506: identification of the cyr gene cluster and toxin analysis.

Mazmouz R, Chapuis-Hugon F, Mann S, Pichon V, Méjean A, Ploux O.

Appl Environ Microbiol. 2010 Aug;76(15):4943-9. doi: 10.1128/AEM.00717-10. Epub 2010 Jun 4.

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