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Items: 17


Genome-Wide Sequencing of Cell-Free DNA Identifies Copy-Number Alterations That Can Be Used for Monitoring Response to Immunotherapy in Cancer Patients.

Jensen TJ, Goodman AM, Kato S, Ellison CK, Daniels GA, Kim L, Nakashe P, McCarthy E, Mazloom AR, McLennan G, Grosu DS, Ehrich M, Kurzrock R.

Mol Cancer Ther. 2019 Feb;18(2):448-458. doi: 10.1158/1535-7163.MCT-18-0535. Epub 2018 Dec 6.


Using Targeted Sequencing of Paralogous Sequences for Noninvasive Detection of Selected Fetal Aneuploidies.

Ellison CK, Sun Y, Hogg G, Fox J, Tao H, McCarthy E, Sagoe B, Azab MA, Mazloom AR, Tynan J, Burcham T, Kim SK, van den Boom D, Ehrich M, Jensen TJ.

Clin Chem. 2016 Dec;62(12):1621-1629. Epub 2016 Sep 30.


Clinical validation of a noninvasive prenatal test for genomewide detection of fetal copy number variants.

Lefkowitz RB, Tynan JA, Liu T, Wu Y, Mazloom AR, Almasri E, Hogg G, Angkachatchai V, Zhao C, Grosu DS, McLennan G, Ehrich M.

Am J Obstet Gynecol. 2016 Aug;215(2):227.e1-227.e16. doi: 10.1016/j.ajog.2016.02.030. Epub 2016 Feb 17.


Application of risk score analysis to low-coverage whole genome sequencing data for the noninvasive detection of trisomy 21, trisomy 18, and trisomy 13.

Tynan JA, Kim SK, Mazloom AR, Zhao C, McLennan G, Tim R, Liu L, Hannum G, Hull A, Bombard AT, Oeth P, Burcham T, van den Boom D, Ehrich M.

Prenat Diagn. 2016 Jan;36(1):56-62. doi: 10.1002/pd.4712. Epub 2015 Dec 23.


Determination of fetal DNA fraction from the plasma of pregnant women using sequence read counts.

Kim SK, Hannum G, Geis J, Tynan J, Hogg G, Zhao C, Jensen TJ, Mazloom AR, Oeth P, Ehrich M, van den Boom D, Deciu C.

Prenat Diagn. 2015 Aug;35(8):810-5. doi: 10.1002/pd.4615. Epub 2015 Jun 3.


Non-invasive prenatal chromosomal aneuploidy testing--clinical experience: 100,000 clinical samples.

McCullough RM, Almasri EA, Guan X, Geis JA, Hicks SC, Mazloom AR, Deciu C, Oeth P, Bombard AT, Paxton B, Dharajiya N, Saldivar JS.

PLoS One. 2014 Oct 7;9(10):e109173. doi: 10.1371/journal.pone.0109173. eCollection 2014.


ELK1 transcription factor linked to dysregulated striatal mu opioid receptor signaling network and OPRM1 polymorphism in human heroin abusers.

Sillivan SE, Whittard JD, Jacobs MM, Ren Y, Mazloom AR, Caputi FF, Horvath M, Keller E, Ma'ayan A, Pan YX, Chiang LW, Hurd YL.

Biol Psychiatry. 2013 Oct 1;74(7):511-9. doi: 10.1016/j.biopsych.2013.04.012. Epub 2013 May 20.


Noninvasive prenatal detection of sex chromosomal aneuploidies by sequencing circulating cell-free DNA from maternal plasma.

Mazloom AR, Džakula Ž, Oeth P, Wang H, Jensen T, Tynan J, McCullough R, Saldivar JS, Ehrich M, van den Boom D, Bombard AT, Maeder M, McLennan G, Meschino W, Palomaki GE, Canick JA, Deciu C.

Prenat Diagn. 2013 Jun;33(6):591-7. doi: 10.1002/pd.4127.


High-throughput massively parallel sequencing for fetal aneuploidy detection from maternal plasma.

Jensen TJ, Zwiefelhofer T, Tim RC, Džakula Ž, Kim SK, Mazloom AR, Zhu Z, Tynan J, Lu T, McLennan G, Palomaki GE, Canick JA, Oeth P, Deciu C, van den Boom D, Ehrich M.

PLoS One. 2013;8(3):e57381. doi: 10.1371/journal.pone.0057381. Epub 2013 Mar 6.


Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors.

Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL, Pevny L, Nicolis S, Ma'ayan A, Rendl M.

Dev Cell. 2012 Nov 13;23(5):981-94. doi: 10.1016/j.devcel.2012.10.013.


Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages.

Gautier EL, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, Helft J, Chow A, Elpek KG, Gordonov S, Mazloom AR, Ma'ayan A, Chua WJ, Hansen TH, Turley SJ, Merad M, Randolph GJ; Immunological Genome Consortium.

Nat Immunol. 2012 Nov;13(11):1118-28. doi: 10.1038/ni.2419. Epub 2012 Sep 30.


Activation of alternate prosurvival pathways accounts for acquired sunitinib resistance in U87MG glioma xenografts.

Zhou Q, Lv H, Mazloom AR, Xu H, Ma'ayan A, Gallo JM.

J Pharmacol Exp Ther. 2012 Nov;343(2):509-19. doi: 10.1124/jpet.112.196097. Epub 2012 Aug 6.


A systems approach identifies HIPK2 as a key regulator of kidney fibrosis.

Jin Y, Ratnam K, Chuang PY, Fan Y, Zhong Y, Dai Y, Mazloom AR, Chen EY, D'Agati V, Xiong H, Ross MJ, Chen N, Ma'ayan A, He JC.

Nat Med. 2012 Mar 11;18(4):580-8. doi: 10.1038/nm.2685.


Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.

Mazloom AR, Dannenfelser R, Clark NR, Grigoryan AV, Linder KM, Cardozo TJ, Bond JC, Boran AD, Iyengar R, Malovannaya A, Lanz RB, Ma'ayan A.

PLoS Comput Biol. 2011 Dec;7(12):e1002319. doi: 10.1371/journal.pcbi.1002319. Epub 2011 Dec 29.


ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments.

Lachmann A, Xu H, Krishnan J, Berger SI, Mazloom AR, Ma'ayan A.

Bioinformatics. 2010 Oct 1;26(19):2438-44. doi: 10.1093/bioinformatics/btq466. Epub 2010 Aug 13.


Mesenchymal and haematopoietic stem cells form a unique bone marrow niche.

Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS.

Nature. 2010 Aug 12;466(7308):829-34. doi: 10.1038/nature09262.


Chromatin remodeling in silico: a stochastic model for SWI/SNF.

Mazloom AR, Basu K, Mandal SS, Das SK.

Biosystems. 2010 Mar;99(3):179-91. doi: 10.1016/j.biosystems.2009.11.001. Epub 2009 Nov 27.


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