Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 15

1.

First-in-human phase I study of pictilisib (GDC-0941), a potent pan-class I phosphatidylinositol-3-kinase (PI3K) inhibitor, in patients with advanced solid tumors.

Sarker D, Ang JE, Baird R, Kristeleit R, Shah K, Moreno V, Clarke PA, Raynaud FI, Levy G, Ware JA, Mazina K, Lin R, Wu J, Fredrickson J, Spoerke JM, Lackner MR, Yan Y, Friedman LS, Kaye SB, Derynck MK, Workman P, de Bono JS.

Clin Cancer Res. 2015 Jan 1;21(1):77-86. doi: 10.1158/1078-0432.CCR-14-0947. Epub 2014 Nov 4.

2.

The effect of MK-0524, a prostaglandin D(2) receptor antagonist, on prostaglandin D (2)-induced nasal airway obstruction in healthy volunteers.

Van Hecken A, Depré M, De Lepeleire I, Thach C, Oeyen M, Van Effen J, Laethem T, Mazina K, Crumley T, Wenning L, Gottesdiener KM, Deutsch P, Clement P, Lai E, de Hoon JN.

Eur J Clin Pharmacol. 2007 Feb;63(2):135-41. Epub 2007 Jan 3.

PMID:
17200838
3.

A study to determine the effects of food and multiple dosing on the pharmacokinetics of vorinostat given orally to patients with advanced cancer.

Rubin EH, Agrawal NG, Friedman EJ, Scott P, Mazina KE, Sun L, Du L, Ricker JL, Frankel SR, Gottesdiener KM, Wagner JA, Iwamoto M.

Clin Cancer Res. 2006 Dec 1;12(23):7039-45.

4.

Single- and multiple-dose pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, in man.

Agrawal NG, Porras AG, Matthews CZ, Rose MJ, Woolf EJ, Musser BJ, Dynder AL, Mazina KE, Lasseter KC, Hunt TL, Schwartz JI, McCrea JB, Gottesdiener KM.

J Clin Pharmacol. 2003 Mar;43(3):268-76.

PMID:
12638395
5.

Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.

Lobell RB, Liu D, Buser CA, Davide JP, DePuy E, Hamilton K, Koblan KS, Lee Y, Mosser S, Motzel SL, Abbruzzese JL, Fuchs CS, Rowinsky EK, Rubin EH, Sharma S, Deutsch PJ, Mazina KE, Morrison BW, Wildonger L, Yao SL, Kohl NE.

Mol Cancer Ther. 2002 Jul;1(9):747-58.

6.

A phase I and pharmacological study of the farnesyl protein transferase inhibitor L-778,123 in patients with solid malignancies.

Britten CD, Rowinsky EK, Soignet S, Patnaik A, Yao SL, Deutsch P, Lee Y, Lobell RB, Mazina KE, McCreery H, Pezzuli S, Spriggs D.

Clin Cancer Res. 2001 Dec;7(12):3894-903.

7.

Purification and reconstitution of a recombinant human neurokinin-1 receptor.

Mazina KE, Strader CD, Tota MR, Daniel S, Fong TM.

J Recept Signal Transduct Res. 1996 May-Jul;16(3-4):191-207.

PMID:
8897311
8.

Characterization of a fluorescent substance P analog.

Tota MR, Daniel S, Sirotina A, Mazina KE, Fong TM, Longmore J, Strader CD.

Biochemistry. 1994 Nov 8;33(44):13079-86.

PMID:
7524660
9.

Expression and solubilization of a recombinant human neurokinin-1 receptor in insect cells.

Mazina KE, Strader CD, Fong TM.

J Recept Res. 1994 Jan;14(1):63-73.

PMID:
8158583
10.

cDNA sequence and heterologous expression of the human neurokinin-3 receptor.

Huang RR, Cheung AH, Mazina KE, Strader CD, Fong TM.

Biochem Biophys Res Commun. 1992 Apr 30;184(2):966-72.

PMID:
1374246
11.

Identification of organic N-chloramines in vitro in stomach fluid from the rat after chlorination.

Scully FE Jr, Mazina KE, Ringhand HP, Chess EK, Campbell JA, Johnson JD.

Chem Res Toxicol. 1990 Jul-Aug;3(4):301-6.

PMID:
2133076
12.

(+-)-(1 alpha,2 beta,3 alpha)-9-[2,3-bis(hydroxymethyl)-cyclobutyl] guanine [(+-)-BHCG or SQ 33,054]: a potent and selective inhibitor of herpesviruses.

Field AK, Tuomari AV, McGeever-Rubin B, Terry BJ, Mazina KE, Haffey ML, Hagen ME, Clark JM, Braitman A, Slusarchyk WA, et al.

Antiviral Res. 1990 Jan;13(1):41-52.

PMID:
2159261
13.

Broad-spectrum antiviral activity of the acyclic guanosine phosphonate (R,S)-HPMPG.

Terry BJ, Mazina KE, Tuomari AV, Haffey ML, Hagen M, Feldman A, Slusarchyk WA, Young MG, Zahler R, Field AK.

Antiviral Res. 1988 Dec 1;10(4-5):235-51.

PMID:
2852486
14.

Small molecular weight organic amino nitrogen compounds in treated municipal wastewater.

Scully FE, Howell GD, Penn HH, Mazina K, Johnson JD.

Environ Sci Technol. 1988 Oct;22(10):1186-90. doi: 10.1021/es00175a010. No abstract available.

PMID:
22148613
15.

Quantitation and identification of organic N-chloramines formed in stomach fluid on ingestion of aqueous hypochlorite.

Scully FE Jr, Mazina K, Sonenshine D, Kopfler F.

Environ Health Perspect. 1986 Nov;69:259-65.

Supplemental Content

Loading ...
Support Center