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Items: 19


Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation.

Bassett EA, Tokarew N, Allemano EA, Mazerolle C, Morin K, Mears AJ, McNeill B, Ringuette R, Campbell C, Smiley S, Pokrajac NT, Dubuc AM, Ramaswamy V, Northcott PA, Remke M, Monnier PP, Potter D, Paes K, Kirkpatrick LL, Coker KJ, Rice DS, Perez-Iratxeta C, Taylor MD, Wallace VA.

Elife. 2016 Nov 8;5. pii: e16764. doi: 10.7554/eLife.16764.


Sortilin regulates sorting and secretion of Sonic hedgehog.

Campbell C, Beug S, Nickerson PE, Peng J, Mazerolle C, Bassett EA, Ringuette R, Jama FA, Morales C, Christ A, Wallace VA.

J Cell Sci. 2016 Oct 15;129(20):3832-3844. Epub 2016 Sep 15.


A Notch-Gli2 axis sustains Hedgehog responsiveness of neural progenitors and Müller glia.

Ringuette R, Atkins M, Lagali PS, Bassett EA, Campbell C, Mazerolle C, Mears AJ, Picketts DJ, Wallace VA.

Dev Biol. 2016 Mar 1;411(1):85-100. doi: 10.1016/j.ydbio.2016.01.006. Epub 2016 Feb 2.


Hedgehog regulates Norrie disease protein to drive neural progenitor self-renewal.

McNeill B, Mazerolle C, Bassett EA, Mears AJ, Ringuette R, Lagali P, Picketts DJ, Paes K, Rice D, Wallace VA.

Hum Mol Genet. 2013 Mar 1;22(5):1005-16. doi: 10.1093/hmg/dds505. Epub 2012 Nov 30.


Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1.

Haque ME, Mount MP, Safarpour F, Abdel-Messih E, Callaghan S, Mazerolle C, Kitada T, Slack RS, Wallace V, Shen J, Anisman H, Park DS.

J Biol Chem. 2012 Jun 29;287(27):23162-70. doi: 10.1074/jbc.M112.346437. Epub 2012 Apr 17.


Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.

McNeill B, Perez-Iratxeta C, Mazerolle C, Furimsky M, Mishina Y, Andrade-Navarro MA, Wallace VA.

Mol Cell Neurosci. 2012 Mar;49(3):333-40. doi: 10.1016/j.mcn.2011.12.008. Epub 2012 Jan 16.


Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina.

Cwinn MA, Mazerolle C, McNeill B, Ringuette R, Thurig S, Hui CC, Wallace VA.

J Neurosci. 2011 Mar 30;31(13):5169-80. doi: 10.1523/JNEUROSCI.5495-10.2011.


Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity.

Wall DS, Mears AJ, McNeill B, Mazerolle C, Thurig S, Wang Y, Kageyama R, Wallace VA.

J Cell Biol. 2009 Jan 12;184(1):101-12. doi: 10.1083/jcb.200805155. Epub 2009 Jan 5.


Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.

Medina CF, Mazerolle C, Wang Y, Bérubé NG, Coupland S, Gibbons RJ, Wallace VA, Picketts DJ.

Hum Mol Genet. 2009 Mar 1;18(5):966-77. doi: 10.1093/hmg/ddn424. Epub 2008 Dec 16.


[Prospects 2007 in vesical pathology. Introduction].

Allory Y, Compérat E, Mazerolle C, Sibony M.

Ann Pathol. 2008 Sep;28(4):270-1. doi: 10.1016/j.annpat.2008.06.024. Epub 2008 Sep 3. French. No abstract available. Erratum in: Ann Pathol. 2008 Dec;28(6):571.


Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells.

Dakubo GD, Beug ST, Mazerolle CJ, Thurig S, Wang Y, Wallace VA.

Brain Res. 2008 Sep 4;1228:27-42. doi: 10.1016/j.brainres.2008.06.058. Epub 2008 Jun 24.


Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye.

Dakubo GD, Mazerolle C, Furimsky M, Yu C, St-Jacques B, McMahon AP, Wallace VA.

Dev Biol. 2008 Aug 1;320(1):242-55. doi: 10.1016/j.ydbio.2008.05.528. Epub 2008 May 20.


Ciliary margin transdifferentiation from neural retina is controlled by canonical Wnt signaling.

Liu H, Xu S, Wang Y, Mazerolle C, Thurig S, Coles BL, Ren JC, Taketo MM, van der Kooy D, Wallace VA.

Dev Biol. 2007 Aug 1;308(1):54-67. Epub 2007 May 16.


Direct and indirect effects of hedgehog pathway activation in the mammalian retina.

Yu C, Mazerolle CJ, Thurig S, Wang Y, Pacal M, Bremner R, Wallace VA.

Mol Cell Neurosci. 2006 Jul;32(3):274-82.


Expression of Notch and Wnt pathway components and activation of Notch signaling in medulloblastomas from heterozygous patched mice.

Dakubo GD, Mazerolle CJ, Wallace VA.

J Neurooncol. 2006 Sep;79(3):221-7. Epub 2006 Apr 6.


Retinal ganglion cell-derived sonic hedgehog locally controls proliferation and the timing of RGC development in the embryonic mouse retina.

Wang Y, Dakubo GD, Thurig S, Mazerolle CJ, Wallace VA.

Development. 2005 Nov;132(22):5103-13. Epub 2005 Oct 19.


Abnormalities of the vitreoretinal interface caused by dysregulated Hedgehog signaling during retinal development.

Black GC, Mazerolle CJ, Wang Y, Campsall KD, Petrin D, Leonard BC, Damji KF, Evans DG, McLeod D, Wallace VA.

Hum Mol Genet. 2003 Dec 15;12(24):3269-76. Epub 2003 Oct 21.


Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development.

Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA.

Development. 2003 Jul;130(13):2967-80.


Characterization of transgene expression and Cre recombinase activity in a panel of Thy-1 promoter-Cre transgenic mice.

Campsall KD, Mazerolle CJ, De Repentingy Y, Kothary R, Wallace VA.

Dev Dyn. 2002 Jun;224(2):135-43.

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