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Items: 1 to 50 of 127

1.

Shortened Spadin Analogs Display Better TREK-1 Inhibition, In Vivo Stability and Antidepressant Activity.

Djillani A, Pietri M, Moreno S, Heurteaux C, Mazella J, Borsotto M.

Front Pharmacol. 2017 Sep 12;8:643. doi: 10.3389/fphar.2017.00643. eCollection 2017.

2.

Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin.

Hivelin C, Béraud-Dufour S, Devader C, Abderrahmani A, Moreno S, Moha Ou Maati H, Djillani A, Heurteaux C, Borsotto M, Mazella J, Coppola T.

J Diabetes Res. 2016;2016:3142175. doi: 10.1155/2016/3142175. Epub 2016 Dec 25.

3.

Increased Brain Neurotensin and NTSR2 Lead to Weak Nociception in NTSR3/Sortilin Knockout Mice.

Devader C, Moreno S, Roulot M, Deval E, Dix T, Morales CR, Mazella J.

Front Neurosci. 2016 Nov 24;10:542. eCollection 2016.

4.

Serum sortilin-derived propeptides concentrations are decreased in major depressive disorder patients.

Devader C, Roulot M, Moréno S, Minelli A, Bortolomasi M, Congiu C, Gennarelli M, Borsotto M, Heurteaux C, Mazella J.

J Affect Disord. 2017 Jan 15;208:443-447. doi: 10.1016/j.jad.2016.10.049. Epub 2016 Nov 4.

PMID:
27838145
5.

Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation.

Béraud-Dufour S, Devader C, Massa F, Roulot M, Coppola T, Mazella J.

Int J Mol Sci. 2016 Nov 8;17(11). pii: E1860. Review.

6.

Sortilin derived propeptide regulation during adipocyte differentiation and inflammation.

Hivelin C, Mazella J, Coppola T.

Biochem Biophys Res Commun. 2017 Jan 1;482(1):87-92. doi: 10.1016/j.bbrc.2016.10.139. Epub 2016 Nov 2.

PMID:
27816451
7.

Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the "spadin" Antidepressant.

Vallée N, Lambrechts K, De Maistre S, Royal P, Mazella J, Borsotto M, Heurteaux C, Abraini J, Risso JJ, Blatteau JE.

Front Physiol. 2016 Feb 16;7:42. doi: 10.3389/fphys.2016.00042. eCollection 2016.

8.

Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation.

Etiévant A, Oosterhof C, Bétry C, Abrial E, Novo-Perez M, Rovera R, Scarna H, Devader C, Mazella J, Wegener G, Sánchez C, Dkhissi-Benyahya O, Gronfier C, Coizet V, Beaulieu JM, Blier P, Lucas G, Haddjeri N.

EBioMedicine. 2015 Jul 7;2(8):898-908. doi: 10.1016/j.ebiom.2015.06.023. eCollection 2015 Aug.

9.

In vitro and in vivo regulation of synaptogenesis by the novel antidepressant spadin.

Devader C, Khayachi A, Veyssière J, Moha Ou Maati H, Roulot M, Moreno S, Borsotto M, Martin S, Heurteaux C, Mazella J.

Br J Pharmacol. 2015 May;172(10):2604-17. doi: 10.1111/bph.13083. Epub 2015 Mar 24.

10.

Targeting two-pore domain K(+) channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept.

Borsotto M, Veyssiere J, Moha Ou Maati H, Devader C, Mazella J, Heurteaux C.

Br J Pharmacol. 2015 Feb;172(3):771-84. doi: 10.1111/bph.12953. Epub 2014 Nov 24. Review.

11.

Impairement of HT29 Cancer Cells Cohesion by the Soluble Form of Neurotensin Receptor-3.

Massa F, Devader C, Lacas-Gervais S, Béraud-Dufour S, Coppola T, Mazella J.

Genes Cancer. 2014 Jul;5(7-8):240-249.

12.

Retroinverso analogs of spadin display increased antidepressant effects.

Veyssiere J, Moha Ou Maati H, Mazella J, Gaudriault G, Moreno S, Heurteaux C, Borsotto M.

Psychopharmacology (Berl). 2015 Feb;232(3):561-74. doi: 10.1007/s00213-014-3683-2. Epub 2014 Aug 2.

13.

Focal adhesion kinase dependent activation of the PI3 kinase pathway by the functional soluble form of neurotensin receptor-3 in HT29 cells.

Massa F, Devader C, Béraud-Dufour S, Brau F, Coppola T, Mazella J.

Int J Biochem Cell Biol. 2013 May;45(5):952-9. doi: 10.1016/j.biocel.2013.01.020. Epub 2013 Feb 8.

PMID:
23395631
14.

The anti-apoptotic role of neurotensin.

Devader C, Béraud-Dufour S, Coppola T, Mazella J.

Cells. 2013 Mar 4;2(1):124-35. doi: 10.3390/cells2010124.

15.

Neurotensin and its receptors in the control of glucose homeostasis.

Mazella J, Béraud-Dufour S, Devader C, Massa F, Coppola T.

Front Endocrinol (Lausanne). 2012 Nov 26;3:143. doi: 10.3389/fendo.2012.00143. eCollection 2012.

16.

A human TREK-1/HEK cell line: a highly efficient screening tool for drug development in neurological diseases.

Moha ou Maati H, Peyronnet R, Devader C, Veyssiere J, Labbal F, Gandin C, Mazella J, Heurteaux C, Borsotto M.

PLoS One. 2011;6(10):e25602. doi: 10.1371/journal.pone.0025602. Epub 2011 Oct 14.

17.

Neurotensin-induced Erk1/2 phosphorylation and growth of human colonic cancer cells are independent from growth factors receptors activation.

Massa F, Tormo A, Béraud-Dufour S, Coppola T, Mazella J.

Biochem Biophys Res Commun. 2011 Oct 14;414(1):118-22. doi: 10.1016/j.bbrc.2011.09.034. Epub 2011 Sep 14.

PMID:
21945442
18.

Spadin as a new antidepressant: absence of TREK-1-related side effects.

Moha Ou Maati H, Veyssiere J, Labbal F, Coppola T, Gandin C, Widmann C, Mazella J, Heurteaux C, Borsotto M.

Neuropharmacology. 2012 Jan;62(1):278-88. doi: 10.1016/j.neuropharm.2011.07.019. Epub 2011 Jul 22.

PMID:
21807005
19.

Neurotensin is a regulator of insulin secretion in pancreatic beta-cells.

Béraud-Dufour S, Abderrahmani A, Noel J, Brau F, Waeber G, Mazella J, Coppola T.

Int J Biochem Cell Biol. 2010 Oct;42(10):1681-8. doi: 10.1016/j.biocel.2010.06.018. Epub 2010 Jun 30.

PMID:
20601081
20.

Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic.

Hughes FM Jr, Shaner BE, May LA, Zotian L, Brower JO, Woods RJ, Cash M, Morrow D, Massa F, Mazella J, Dix TA.

J Med Chem. 2010 Jun 24;53(12):4623-32. doi: 10.1021/jm100092s.

21.

Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

Mazella J, Pétrault O, Lucas G, Deval E, Béraud-Dufour S, Gandin C, El-Yacoubi M, Widmann C, Guyon A, Chevet E, Taouji S, Conductier G, Corinus A, Coppola T, Gobbi G, Nahon JL, Heurteaux C, Borsotto M.

PLoS Biol. 2010 Apr 13;8(4):e1000355. doi: 10.1371/journal.pbio.1000355.

22.

Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic beta-TC3 cells.

Béraud-Dufour S, Coppola T, Massa F, Mazella J.

Int J Biochem Cell Biol. 2009 Dec;41(12):2398-402.

PMID:
19891061
23.

Notch ligand-dependent gene expression in human endometrial stromal cells.

Mikhailik A, Mazella J, Liang S, Tseng L.

Biochem Biophys Res Commun. 2009 Oct 23;388(3):479-82. doi: 10.1016/j.bbrc.2009.07.037. Epub 2009 Jul 14.

PMID:
19607805
24.

Neurotensin protects pancreatic beta cells from apoptosis.

Coppola T, Béraud-Dufour S, Antoine A, Vincent JP, Mazella J.

Int J Biochem Cell Biol. 2008;40(10):2296-302. doi: 10.1016/j.biocel.2008.03.015. Epub 2008 Apr 1.

PMID:
18456542
25.

Expression of Delta-like protein 4 in the human endometrium.

Mazella J, Liang S, Tseng L.

Endocrinology. 2008 Jan;149(1):15-9. Epub 2007 Oct 4.

26.

Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2.

Sharif N, Gendron L, Wowchuk J, Sarret P, Mazella J, Beaudet A, Stroh T.

Endocrinology. 2007 May;148(5):2095-105. Epub 2007 Feb 1.

PMID:
17272399
27.

Internalization and recycling properties of neurotensin receptors.

Mazella J, Vincent JP.

Peptides. 2006 Oct;27(10):2488-92. Epub 2006 Aug 9. Review.

PMID:
16901585
28.

Progestagenic effects of tibolone are target gene-specific in human endometrial cells.

Zhang W, Mazella J, Kloosterboer HJ, Tseng L.

J Soc Gynecol Investig. 2006 Sep;13(6):459-65. Epub 2006 Jul 31.

PMID:
16879988
29.

Functional roles of the NTS2 and NTS3 receptors.

Mazella J, Vincent JP.

Peptides. 2006 Oct;27(10):2469-75. Epub 2006 Jul 26. Review.

PMID:
16872720
30.

Internalization-dependent regulation of HT29 cell proliferation by neurotensin.

Navarro V, Martin S, Mazella J.

Peptides. 2006 Oct;27(10):2502-7. Epub 2006 Jul 25.

PMID:
16870305
31.

Effects of tibolone on nuclear receptors in human endometrial cells.

Zhang W, Mazella J, Kloosterboer HJ, Tseng L.

Am J Obstet Gynecol. 2006 Jul;195(1):97-102. Epub 2006 Apr 21.

PMID:
16813748
32.

Sustained neurotensin exposure promotes cell surface recruitment of NTS2 receptors.

Perron A, Sharif N, Gendron L, Lavallée M, Stroh T, Mazella J, Beaudet A.

Biochem Biophys Res Commun. 2006 May 12;343(3):799-808. Epub 2006 Mar 20.

PMID:
16564027
33.

Design, synthesis, and evaluation of the antipsychotic potential of orally bioavailable neurotensin (8-13) analogues containing non-natural arginine and lysine residues.

Hadden MK, Orwig KS, Kokko KP, Mazella J, Dix TA.

Neuropharmacology. 2005 Dec;49(8):1149-59. Epub 2005 Aug 10.

PMID:
16095636
34.

Neurotensin and the neurotensin receptor-3 in microglial cells.

Martin S, Dicou E, Vincent JP, Mazella J.

J Neurosci Res. 2005 Aug 1;81(3):322-6. Review.

PMID:
15957186
35.

Ligand activated relaxin receptor increases the transcription of IGFBP-1 and prolactin in human decidual and endometrial stromal cells.

Tang M, Mazella J, Zhu HH, Tseng L.

Mol Hum Reprod. 2005 Apr;11(4):237-43. Epub 2005 Feb 18.

PMID:
15722441
36.
37.

[Sortilin: protein associated with multiple functions].

Mazella J, Vincent JP.

Med Sci (Paris). 2004 Jun-Jul;20(6-7):629-31. French. No abstract available.

38.

Internalization and trafficking of neurotensin via NTS3 receptors in HT29 cells.

Morinville A, Martin S, Lavallée M, Vincent JP, Beaudet A, Mazella J.

Int J Biochem Cell Biol. 2004 Nov;36(11):2153-68.

PMID:
15313463
39.

Crucial role of neuron-enriched endosomal protein of 21 kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors.

Debaigt C, Hirling H, Steiner P, Vincent JP, Mazella J.

J Biol Chem. 2004 Aug 20;279(34):35687-91. Epub 2004 Jun 7.

41.

Progesterone receptor (hPR) upregulates the fibronectin promoter activity in human decidual fibroblasts.

Tseng L, Tang M, Wang Z, Mazella J.

DNA Cell Biol. 2003 Oct;22(10):633-40.

PMID:
14611684
42.

In vitro analysis of stable, receptor-selective neurotensin[8-13] analogues.

Kokko KP, Hadden MK, Orwig KS, Mazella J, Dix TA.

J Med Chem. 2003 Sep 11;46(19):4141-8.

PMID:
12954066
43.

Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system.

Sarret P, Krzywkowski P, Segal L, Nielsen MS, Petersen CM, Mazella J, Stroh T, Beaudet A.

J Comp Neurol. 2003 Jul 7;461(4):483-505.

PMID:
12746864
44.

Involvement of the neurotensin receptor-3 in the neurotensin-induced migration of human microglia.

Martin S, Vincent JP, Mazella J.

J Neurosci. 2003 Feb 15;23(4):1198-205.

45.

Hox proteins activate the IGFBP-1 promoter and suppress the function of hPR in human endometrial cells.

Gao J, Mazella J, Tseng L.

DNA Cell Biol. 2002 Nov;21(11):819-25.

PMID:
12489992
46.

Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line.

Navarro V, Vincent JP, Mazella J.

Biochem Biophys Res Commun. 2002 Nov 15;298(5):760-4.

PMID:
12419319
47.

Porcine odorant-binding protein selectively binds to a human olfactory receptor.

Matarazzo V, Zsürger N, Guillemot JC, Clot-Faybesse O, Botto JM, Dal Farra C, Crowe M, Demaille J, Vincent JP, Mazella J, Ronin C.

Chem Senses. 2002 Oct;27(8):691-701.

PMID:
12379593
48.

Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line.

Martin S, Navarro V, Vincent JP, Mazella J.

Gastroenterology. 2002 Oct;123(4):1135-43.

PMID:
12360476
49.

Progesterone receptor activates its promoter activity in human endometrial stromal cells.

Tang M, Mazella J, Gao J, Tseng L.

Mol Cell Endocrinol. 2002 Jun 28;192(1-2):45-53.

PMID:
12088866
50.

Endometrial cell specific gene activation during implantation and early pregnancy.

Tseng L, Mazella J.

Front Biosci. 2002 Jun 1;7:d1566-74. Review.

PMID:
12045017

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