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Items: 18

1.

Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole-body homeostasis.

Zhang Q, Duplany A, Moncollin V, Mouradian S, Goillot E, Mazelin L, Gauthier K, Streichenberger N, Angleraux C, Chen J, Ding S, Schaeffer L, Gangloff YG.

J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):35-53. doi: 10.1002/jcsm.12336. Epub 2018 Nov 21.

2.

The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor.

Wang H, Boussouar A, Mazelin L, Tauszig-Delamasure S, Sun Y, Goldschneider D, Paradisi A, Mehlen P.

Mol Cell. 2018 Nov 1;72(3):413-425.e5. doi: 10.1016/j.molcel.2018.08.040. Epub 2018 Oct 4.

3.

mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis.

Mazelin L, Panthu B, Nicot AS, Belotti E, Tintignac L, Teixeira G, Zhang Q, Risson V, Baas D, Delaune E, Derumeaux G, Taillandier D, Ohlmann T, Ovize M, Gangloff YG, Schaeffer L.

J Mol Cell Cardiol. 2016 Aug;97:213-25. doi: 10.1016/j.yjmcc.2016.04.011. Epub 2016 Apr 28.

PMID:
27133769
4.

Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation.

Touvier T, De Palma C, Rigamonti E, Scagliola A, Incerti E, Mazelin L, Thomas JL, D'Antonio M, Politi L, Schaeffer L, Clementi E, Brunelli S.

Cell Death Dis. 2015 Feb 26;6:e1663. doi: 10.1038/cddis.2014.595.

5.

DCC constrains tumour progression via its dependence receptor activity.

Castets M, Broutier L, Molin Y, Brevet M, Chazot G, Gadot N, Paquet A, Mazelin L, Jarrosson-Wuilleme L, Scoazec JY, Bernet A, Mehlen P.

Nature. 2011 Dec 11;482(7386):534-7. doi: 10.1038/nature10708.

PMID:
22158121
6.

Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.

Romanino K, Mazelin L, Albert V, Conjard-Duplany A, Lin S, Bentzinger CF, Handschin C, Puigserver P, Zorzato F, Schaeffer L, Gangloff YG, Rüegg MA.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20808-13. doi: 10.1073/pnas.1111448109. Epub 2011 Dec 5.

7.

Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer.

Coissieux MM, Tomsic J, Castets M, Hampel H, Tuupanen S, Andrieu N, Comeras I, Drouet Y, Lasset C, Liyanarachchi S, Mazelin L, Puisieux A, Saurin JC, Scoazec JY, Wang Q, Aaltonen L, Tanner SM, de la Chapelle A, Bernet A, Mehlen P.

Gastroenterology. 2011 Dec;141(6):2039-46. doi: 10.1053/j.gastro.2011.08.041. Epub 2011 Sep 3.

8.

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.

Risson V, Mazelin L, Roceri M, Sanchez H, Moncollin V, Corneloup C, Richard-Bulteau H, Vignaud A, Baas D, Defour A, Freyssenet D, Tanti JF, Le-Marchand-Brustel Y, Ferrier B, Conjard-Duplany A, Romanino K, Bauché S, Hantaï D, Mueller M, Kozma SC, Thomas G, Rüegg MA, Ferry A, Pende M, Bigard X, Koulmann N, Schaeffer L, Gangloff YG.

J Cell Biol. 2009 Dec 14;187(6):859-74. doi: 10.1083/jcb.200903131.

9.

Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies.

Bernet A, Mazelin L, Coissieux MM, Gadot N, Ackerman SL, Scoazec JY, Mehlen P.

Gastroenterology. 2007 Dec;133(6):1840-8. Epub 2007 Aug 2.

10.

Netrin-1 controls colorectal tumorigenesis by regulating apoptosis.

Mazelin L, Bernet A, Bonod-Bidaud C, Pays L, Arnaud S, Gespach C, Bredesen DE, Scoazec JY, Mehlen P.

Nature. 2004 Sep 2;431(7004):80-4.

11.

The dependence receptors DCC and UNC5H as a link between neuronal guidance and survival.

Mehlen P, Mazelin L.

Biol Cell. 2003 Oct;95(7):425-36. Review.

PMID:
14597260
12.

Src regulates Golgi structure and KDEL receptor-dependent retrograde transport to the endoplasmic reticulum.

Bard F, Mazelin L, Péchoux-Longin C, Malhotra V, Jurdic P.

J Biol Chem. 2003 Nov 21;278(47):46601-6. Epub 2003 Sep 15.

13.

Stress-induced disruption of colonic epithelial barrier: role of interferon-gamma and myosin light chain kinase in mice.

Ferrier L, Mazelin L, Cenac N, Desreumaux P, Janin A, Emilie D, Colombel JF, Garcia-Villar R, Fioramonti J, Bueno L.

Gastroenterology. 2003 Sep;125(3):795-804.

PMID:
12949725
14.

Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog.

Thibert C, Teillet MA, Lapointe F, Mazelin L, Le Douarin NM, Mehlen P.

Science. 2003 Aug 8;301(5634):843-6.

15.

The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment.

Thiebault K, Mazelin L, Pays L, Llambi F, Joly MO, Scoazec JY, Saurin JC, Romeo G, Mehlen P.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4173-8. Epub 2003 Mar 24.

16.

Vagally dependent protective action of calcitonin gene-related peptide on colitis.

Mazelin L, Theodorou V, Fioramonti J, Bueno L.

Peptides. 1999 Nov;20(11):1367-74.

PMID:
10612453
17.

Protective role of vagal afferents in experimentally-induced colitis in rats.

Mazelin L, Theodorou V, More J, Fioramonti J, Bueno L.

J Auton Nerv Syst. 1998 Aug 27;73(1):38-45.

PMID:
9808369
18.

Comparative effects of nonpeptide tachykinin receptor antagonists on experimental gut inflammation in rats and guinea-pigs.

Mazelin L, Theodorou V, More J, Emonds-Alt X, Fioramonti J, Bueno L.

Life Sci. 1998;63(4):293-304.

PMID:
9698038

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